Abstract:
:Morphological changes in the disconnected neuro-intermediate lobe were studied in the lizard, Anolis carolinensis from the 2nd to the 14th post-operative day using a threefold aldehyde fixative (Rodríguez, 1969). Two phases of colour change capacity were exhibited: Phase I started immediately after the transection, lasted for 6 days (mean) and was characterised by an excessive MSH release (brown skin). This phase proceeded gradually into Phase II, designated by an interruption by the MSH release (green skin). The degenerative processes and final elimination of neurons in the disconnected neural lobe propagate in a rostro-caudal direction from the transected area. The aminergic fibres (Type II) disappear within 2 days postoperatively, whereas the degeneration continues for more than 10 days in the peptidergic fibres (Type III, IV and V). The glia cells (ependyma and pituicytes) serve as very active macrophages, engulfing fragments of axons already affected by autolysis and transferring them into glial lysosomes. No apparent morphological changes occur in the shift from Phase I to II. The great majority of the secretory cells of the intermediate lobe are not affected by degenerative processes and appear to be markedly activated by the stalk transection. They exhibit numerous mitochondria, well-developed Golgi complexes forming numerous Golgi vesicles and extensive parallel cisternae of the rough endoplasmic reticulum, sometimes forming large intracisternal droplets (7 micron in diameter). Numerous pale vacuoles are seen, especially toward the intact capillaries, suggesting their coupling to the MSH release by extension of the active membrane area toward the perivascular septum. The number of these vacuoles is very markedly reduced in Phase II (no release), whereas the formation of new granules seems to proceed in early stages. The interruption of the MSH release implies a successive refilling of gradually growing secretory granules and a concomitant reduction in the development of the synthetic apparatus. Mechanisms probably involved in the control of the synthesis and release of MSH are discussed.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Larsson L,Rodriguez EM,Meurling Pdoi
10.1007/BF00237724subject
Has Abstractpub_date
1979-06-08 00:00:00pages
1-23issue
1eissn
0302-766Xissn
1432-0878journal_volume
199pub_type
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journal_title:Cell and tissue research
pub_type: 杂志文章,评审
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journal_title:Cell and tissue research
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journal_title:Cell and tissue research
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journal_title:Cell and tissue research
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pub_type: 杂志文章,已发布勘误
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journal_title:Cell and tissue research
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journal_title:Cell and tissue research
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journal_title:Cell and tissue research
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journal_title:Cell and tissue research
pub_type: 杂志文章,评审
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journal_title:Cell and tissue research
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journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
pub_type: 杂志文章
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更新日期:1981-01-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
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更新日期:1994-07-01 00:00:00
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journal_title:Cell and tissue research
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journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
pub_type: 杂志文章,评审
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journal_title:Cell and tissue research
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doi:10.1007/BF00328009
更新日期:1992-11-01 00:00:00
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journal_title:Cell and tissue research
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00234326
更新日期:1979-11-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
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更新日期:1982-01-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219726
更新日期:1976-04-28 00:00:00
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journal_title:Cell and tissue research
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doi:10.1007/BF00236448
更新日期:1980-01-01 00:00:00
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journal_title:Cell and tissue research
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更新日期:2020-01-01 00:00:00
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journal_title:Cell and tissue research
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更新日期:1996-07-01 00:00:00
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journal_title:Cell and tissue research
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更新日期:2001-04-01 00:00:00