Induction of mitotic crossing over in Saccharomyces cerevisiae by breakdown products of dimethylnitrosamine, diethylnitrosamine, 1-naphthylamine and 2-naphthylamine formed by an in vitro hydroxylation system.

abstract：:The adaptive character of inversion polymorphism in Drosophila subobscura is well established. The O(ST) and O(3+4) chromosomal arrangements of this species differ by two overlapping inversions that arose independently on O(3) chromosomes. Nucleotide variation in eight gene regions distributed along inversion O(3) was...

journal_title：Genetics

authors： Munté A,Rozas J,Aguadé M,Segarra C

更新日期：2005-03-01 00:00:00

abstract：:As an ancient segmental tetraploid, the maize (Zea mays L.) genome contains large numbers of paralogs that are expected to have diverged by a minimum of 10% over time. Nearly identical paralogs (NIPs) are defined as paralogous genes that exhibit > or = 98% identity. Sequence analyses of the "gene space" of the maize i...

journal_title：Genetics

authors： Emrich SJ,Li L,Wen TJ,Yandeau-Nelson MD,Fu Y,Guo L,Chou HH,Aluru S,Ashlock DA,Schnable PS

更新日期：2007-01-01 00:00:00

abstract：:Injury triggers regeneration of axons and dendrites. Research has identified factors required for axonal regeneration outside the CNS, but little is known about regeneration triggered by dendrotomy. Here, we study neuronal plasticity triggered by dendrotomy and determine the fate of complex PVD arbors following laser ...

journal_title：Genetics

authors： Oren-Suissa M,Gattegno T,Kravtsov V,Podbilewicz B

更新日期：2017-05-01 00:00:00

abstract：:Twelve mutations affecting nuclear migration, a major developmental phase in Schizophyllum commune, display a complex pattern of complementation and recombination. They are expressed only when a genetic factor controlling this phase of development, the B incompatibility factor, is operative. All twelve mutations are l...

journal_title：Genetics

authors： Dubovoy C

更新日期：1976-03-01 00:00:00

abstract：:Salient features of recombination at ARG4 of Saccharomyces provoke a variation of the double-strand-break repair (DSBR) model that has the following features: (1) Holliday junction cutting is biased in favor of strands upon which DNA synthesis occurred during formation of the joint molecule (this bias ensures that cut...

journal_title：Genetics

authors： Foss HM,Hillers KJ,Stahl FW

更新日期：1999-10-01 00:00:00

abstract：:Sister-chromatid exchanges (SCE) were studied in allium cepa L. meristematic cells at the second and third divisions after BrdUrd-substitution during just the first or during the second and third cycles, respectively. The observed SCE nonreciprocal/reciprocal ratios detected at the third division in both experiments, ...

journal_title：Genetics

authors： Schvartzman JB,Cortés F,González-Fernández A,Gutiérrez C,López-Sáez JF

更新日期：1979-08-01 00:00:00

abstract：:One of the key factors contributing to the success of a quantitative trait locus (QTL) mapping experiment is the precision with which QTL positions can be estimated. We show, using simulations, that QTL mapping precision for an experimental cross can be increased by the use of a genotypically selected sample of indivi...

journal_title：Genetics

authors： Xu Z,Zou F,Vision TJ

更新日期：2005-05-01 00:00:00

abstract：:Amoebae of the Colonia (CL) strain, which normally produce plasmodia in clones, are shown to cross with mt3 and mt4 amoebae under appropriate conditions. Strains carrying mt3 and mt4 in a CL genetic background were constructed and used in the genetic analysis of mutants isolated in CL. ...

journal_title：Genetics

authors： Adler PN,Holt CE

更新日期：1974-12-01 00:00:00

abstract：:Evolutionary models appropriate for analyzing nucleotide sequences that are subject to constraints on secondary structure are developed. The models consider the evolution of pairs of nucleotides, and they incorporate the effects of base-pairing constraints on nucleotide substitution rates by introducing a new paramete...

journal_title：Genetics

authors： Muse SV

更新日期：1995-03-01 00:00:00

abstract：:Two strains of Drosophila melanogaster derived from different geographical localities were subjected to selection for fast and slow developmental rate. Four enzyme polymorphisms were monitored for their response to such selection. Significant changes in allele frequencies were effected for the alphaGpdh and 6Pgd polym...

journal_title：Genetics

authors： Cavener DR

更新日期：1983-09-01 00:00:00

abstract：:We have examined the effects of prolonged histidine deprivation on the reversion of Salmonella typhimurium histidine auxotrophs containing either hisG46, a missense mutation (CTC----CCC), or hisG428, an ochre mutation (CAA----TAA). Both of these mutants can revert to His+ via intragenic and extragenic mechanisms. Wher...

journal_title：Genetics

authors： Prival MJ,Cebula TA

更新日期：1992-10-01 00:00:00

abstract：:A mutant strain of Chlamydomonas reinhardi which is UV sensitive as a result of a single-gene chromosomal mutation has also been found to exhibit reduced recombination. In crosses homozygous for the mutant allele, a reduction in recombination frequency was demonstrated in two different linkage groups and in three diff...

journal_title：Genetics

authors： Rosen H,Ebersold WT

更新日期：1972-06-01 00:00:00

abstract：:The noncanonical Frizzled/planar cell polarity (PCP) pathway regulates establishment of polarity within the plane of an epithelium to generate diversity of cell fates, asymmetric, but highly aligned structures, or to orchestrate the directional migration of cells during convergent extension during vertebrate gastrulat...

journal_title：Genetics

authors： Dollar G,Gombos R,Barnett AA,Sanchez Hernandez D,Maung SM,Mihály J,Jenny A

更新日期：2016-03-01 00:00:00

abstract：:The RNA polymerase II (Pol-II) holoenzyme, responsible for messenger RNA production, typically consists of 10-12 subunits. Our laboratory previously demonstrated that maternally deposited, long, noncoding, template RNAs are essential for programmed genome rearrangements in the ciliate Oxytricha trifallax. Here we show...

journal_title：Genetics

authors： Khurana JS,Wang X,Chen X,Perlman DH,Landweber LF

更新日期：2014-07-01 00:00:00

abstract：:We recently described a yeast assay suitable for genetic screening in which simple religation nonhomologous end-joining (NHEJ) and single-strand annealing (SSA) compete for repair of an I-SceI-created double-strand break. Here, the required allele has been introduced into an array of 4781 MATa deletion mutants and eac...

journal_title：Genetics

authors： Wilson TE

更新日期：2002-10-01 00:00:00

abstract：:At pH 6.8, a substantial fraction of recombinant colonies obtained from conjugation with an HfrH donor contained multiple recombinant classes in a single colony (polygenotype colony). In contrast, when the conjugation was performed at pH 7.6, the number of polygenotypic colonies was drastically reduced, and the recomb...

journal_title：Genetics

authors： Ou JT

更新日期：1975-07-01 00:00:00

abstract：:Active endogenous transposable elements, useful tools for gene isolation, have not been reported from any legume species. An active transposable element was suggested to reside in the W4 locus that governs flower color in soybean. Through biochemical and molecular analyses of several revertants of the w4-m allele, we ...

journal_title：Genetics

authors： Xu M,Brar HK,Grosic S,Palmer RG,Bhattacharyya MK

更新日期：2010-01-01 00:00:00

abstract：:The transmission of transposed Ac elements in progeny derived by self-pollination of ten transformed tomato plants has been examined by Southern hybridization analysis. We show that six of these primary transformants have transmitted a transposed Ac to at least one progeny. One of the families was segregating for at l...

journal_title：Genetics

authors： Belzile F,Lassner MW,Tong Y,Khush R,Yoder JI

更新日期：1989-09-01 00:00:00

abstract：:To investigate the regulation of Drosophila melanogaster behavior by biogenic amines, we have exploited the broad requirement of the vesicular monoamine transporter (VMAT) for the vesicular storage and exocytotic release of all monoamine neurotransmitters. We used the Drosophila VMAT (dVMAT) null mutant to globally ab...

journal_title：Genetics

authors： Chen A,Ng F,Lebestky T,Grygoruk A,Djapri C,Lawal HO,Zaveri HA,Mehanzel F,Najibi R,Seidman G,Murphy NP,Kelly RL,Ackerson LC,Maidment NT,Jackson FR,Krantz DE

更新日期：2013-01-01 00:00:00

abstract：:Data are presented for 2,393 progeny from a number of crosses related to a study in ecological genetics of the Burnsi and Kandiyohi polymorphisms in natural populations of the leopard frog, Rana pipiens. No significant differences in viability were found between wild-type homozygotes (+/+) and Burnsi heterozygotes (B/...

journal_title：Genetics

authors： Merrell DJ

更新日期：1972-01-01 00:00:00

abstract：:Homolog recombination and unequal sister chromatid recombination were monitored in rad1-1/rad1-1 diploid yeast cells deficient for excision repair, and in control cells, RAD1/rad1-1, after exposure to UV irradiation. In a rad1-1/rad1-1 diploid, UV irradiation stimulated much more sister chromatid recombination relativ...

journal_title：Genetics

authors： Kadyk LC,Hartwell LH

更新日期：1993-03-01 00:00:00

abstract：:Rare genetic variants have recently been studied for genome-wide associations with human complex diseases. Existing rare variant methods are based on the hypothesis-testing framework that predefined variant sets need to be tested separately. The power of those methods is contingent upon accurate selection of variants ...

journal_title：Genetics

authors： Zhang Y,Ghosh S,Hakonarson H

更新日期：2014-11-01 00:00:00

abstract：:Telomeric restriction fragments were genetically mapped to a previously described linkage map of Magnaporthe grisea, using RFLPs identified by a synthetic probe. (TTAGGG)3. Frequent rearrangement of telomeric sequences was observed in progeny isolates creating a potential for misinterpretation of data. Therefore a con...

journal_title：Genetics

authors： Farman ML,Leong SA

更新日期：1995-06-01 00:00:00

abstract：:Isogenic lines, in which chromosomes sampled from natural populations of C. melanogaster are substituted into a common genetic background, were used to detect and partially characterize autosomal factors that affect the activities of the two pentose phosphate pathway enzymes, glucose 6-phosphate dehydrogenase (G6PD) a...

journal_title：Genetics

authors： Laurie-Ahlberg CC,Williamson JH,Cochrane BJ,Wilton AN,Chasalow FI

更新日期：1981-09-01 00:00:00

abstract：:BTB-zinc finger transcription factors play many important roles in metazoan development. In these proteins, the BTB domain is critical for dimerization and for recruiting cofactors to target genes. Identification of these cofactors is important for understanding how BTB-zinc finger proteins influence transcription. He...

journal_title：Genetics

authors： Howell K,Arur S,Schedl T,Sundaram MV

更新日期：2010-04-01 00:00:00

abstract：:According to theory, F(2) hybrid breakdown (lethality or sterility) is due to incompatibilities between interacting genes of the different species (i.e., the breaking up of coadapted gene complexes). Detection of such incompatibilities is particularly straightforward in haplodiploid species, because virgin F(1) hybrid...

journal_title：Genetics

authors： Gadau J,Page RE Jr,Werren JH

更新日期：1999-12-01 00:00:00

abstract：:Temporally spaced genetic data allow for more accurate inference of population genetic parameters and hypothesis testing on the recent action of natural selection. In this work, we develop a novel likelihood-based method for jointly estimating selection coefficient and allele age from time series data of allele freque...

journal_title：Genetics

authors： He Z,Dai X,Beaumont M,Yu F

更新日期：2020-10-01 00:00:00

abstract：:The primary structures of peptides may be adapted for efficient synthesis as well as proper function. Here, the Saccharomyces cerevisiae genome sequence, DNA microarray expression data, tRNA gene numbers, and functional categorizations of proteins are employed to determine whether the amino acid composition of peptide...

journal_title：Genetics

authors： Akashi H

更新日期：2003-08-01 00:00:00

abstract：:We introduce an approach to revealing the likelihood of different population histories that utilizes an explicit model of sequence evolution for the DNA segment under study. Based on a phylogenetic tree reconstruction method we show that a Tamura-Nei model with heterogeneous mutation rates is a fair description of the...

journal_title：Genetics

authors： Weiss G,von Haeseler A

更新日期：1998-07-01 00:00:00

abstract：:An extending axon growth cone is subjected to attractant and repellent cues. It is not clear how these growth cones discriminate the two opposing forces and select their projection paths. Here, we report that in the Drosophila nerve cord the growth cones of longitudinal tracts are subjected to attraction by the Netrin...

journal_title：Genetics

authors： Bhat KM

更新日期：2005-05-01 00:00:00