Selective dissolution of AuCu and AuAg alloys in vitro and in vivo.

abstract：:The present in vitro study investigates the cellular interaction of primary human osteoblasts with human and bovine solvent dehydrated cancellous bone (SDCB) discs. These are bio-implants from solvent dehydrated, gamma-irradiated preserved human and bovine cancellous bone, pre-treated to remove all cells, genetic comp...

journal_title：Biomaterials

authors： Trentz OA,Hoerstrup SP,Sun LK,Bestmann L,Platz A,Trentz OL

更新日期：2003-09-01 00:00:00

abstract：:Multi-layered poly(glycerol-sebacate) (PGS) scaffolds with controlled pore microarchitectures were fabricated, combined with heart cells, and cultured with perfusion to engineer contractile cardiac muscle constructs. First, one-layered (1L) scaffolds with accordion-like honeycomb shaped pores and elastomeric mechanica...

journal_title：Biomaterials

authors： Park H,Larson BL,Guillemette MD,Jain SR,Hua C,Engelmayr GC Jr,Freed LE

更新日期：2011-03-01 00:00:00

abstract：:In spite of good prospects for bone morphogenetic proteins (BMP) applications, an ideal carrier system for BMPs has not yet been identified. The purpose of this study was to evaluate the osteogenic effect of a fibrin-fibronectin sealing system (FFSS) combined with beta-tricalcium phosphate (beta-TCP) as a carrier syst...

journal_title：Biomaterials

authors： Hong SJ,Kim CS,Han DK,Cho IH,Jung UW,Choi SH,Kim CK,Cho KS

更新日期：2006-07-01 00:00:00

abstract：:Two new formulations of bioactive glasses were used as coatings on titanium alloy (TiAl6V4) implants for prosthetic applications in the orthopaedic field. The biocompatibility of these bioglasses, as well as their osteoconductive properties, were assessed by employing primary cultures of human osteoblasts. A nonbioact...

journal_title：Biomaterials

authors： Oliva A,Salerno A,Locardi B,Riccio V,Della Ragione F,Iardino P,Zappia V

更新日期：1998-06-01 00:00:00

abstract：:The development of artificial microstructures suited for interfacing of peripheral nerves is not only relevant for basic neurophysiological research but also for future prosthetic approaches. Aim of the present study was to provide a detailed analysis of axonal sprouting and reactive tissue changes after implantation ...

journal_title：Biomaterials

authors： Klinge PM,Vafa MA,Brinker T,Brandis A,Walter GF,Stieglitz T,Samii M,Wewetzer K

更新日期：2001-09-01 00:00:00

abstract：:This study is concerned with the effect of dual implantation of calcium and phosphorus upon the structure, corrosion resistance and biocompatibility of titanium. The ions were implanted in sequence, first Ca and then P, both at a dose of 10(17) ions/cm2 at a beam energy of 25 keV. Transmission electron microscopy was ...

journal_title：Biomaterials

authors： Krupa D,Baszkiewicz J,Kozubowski JA,Barcz A,Sobczak JW,Biliński A,Lewandowska-Szumieł M,Rajchel B

更新日期：2005-06-01 00:00:00

abstract：:The use of artificial tissues in regenerative medicine is limited due to hypoxia. As a strategy to overcome this drawback, we have shown that photosynthetic biomaterials can produce and provide oxygen independently of blood perfusion by generating chimeric animal-plant tissues during dermal regeneration. In this work,...

journal_title：Biomaterials

authors： Chávez MN,Schenck TL,Hopfner U,Centeno-Cerdas C,Somlai-Schweiger I,Schwarz C,Machens HG,Heikenwalder M,Bono MR,Allende ML,Nickelsen J,Egaña JT

更新日期：2016-01-01 00:00:00

abstract：:This article is a review of recent developments of polymer-related stents mainly employed in the coronary arteries, including polymer-coated stents, biostable stents and biodegradable stents. Polymer paving is covered as well. The problems with the stents currently investigated and the development of new stents are di...

journal_title：Biomaterials

authors： Peng T,Gibula P,Yao KD,Goosen MF

更新日期：1996-04-01 00:00:00

abstract：:Delivery of polynucleotide-based therapeutics into target cells involves interactions with glycosaminoglycan chains that are located on cell membrane milieu. Mechanisms governing glycosaminoglycan-mediated changes in the nanoparticulate structures of polymer-polynucleotide complexes are unknown, and cannot be fully el...

journal_title：Biomaterials

authors： Meneksedag-Erol D,Tang T,Uludağ H

更新日期：2018-02-01 00:00:00

abstract：:Poly(ether-ether-ketone) (PEEK) has been used as a load bearing orthopaedic implant material with clinical success. All of the orthopaedic applications contain stress concentrations (notches) in their design; however, little work has been done to examine the fatigue behavior of PEEK in the presence of a notch. This wo...

journal_title：Biomaterials

authors： Sobieraj MC,Murphy JE,Brinkman JG,Kurtz SM,Rimnac CM

更新日期：2010-12-01 00:00:00

abstract：:The poor biocompatibility of metallic coronary stents which leads to un-satisfying restenosis rates is mainly caused by contact activation of blood cells, smooth muscle cells and endothelial cells. Mimicking a metal surface with a biocompatible coating that actively suppresses mechanisms leading to restenosis may over...

journal_title：Biomaterials

authors： Lahann J,Klee D,Pluester W,Hoecker H

更新日期：2001-04-01 00:00:00

abstract：:The overwhelming majority of drugs exert their pharmacological effects after reaching their target sites of action, however, these target sites are mainly located in the cytosol or intracellular organelles. Consequently, delivering drugs to the specific organelle is the key to achieve maximum therapeutic effects and m...

journal_title：Biomaterials

authors： Chen Z,Zhang L,Song Y,He J,Wu L,Zhao C,Xiao Y,Li W,Cai B,Cheng H,Li W

更新日期：2015-06-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) have gained increasing attention as a potential approach for the treatment of bone injuries due to their multi-lineage differentiation potential and also their ability to recognize and home to damaged tissue sites, secreting bioactive factors that can modulate the immune system and enhanc...

journal_title：Biomaterials

authors： Bunpetch V,Zhang ZY,Zhang X,Han S,Zongyou P,Wu H,Hong-Wei O

更新日期：2019-03-01 00:00:00

abstract：:In mammalian embryos, cortical interneurons travel long distances among complex three-dimensional tissues before integrating into cortical circuits. Several molecular guiding cues involved in this migration process have been identified, but the influence of physical parameters remains poorly understood. In the present...

journal_title：Biomaterials

authors： Leclech C,Renner M,Villard C,Métin C

更新日期：2019-09-01 00:00:00

abstract：:Polypyrrole (PPy) is a conducting polymer and is obtained electrochemically on an electrode such as indium-tin oxide (ITO). In this study, in order to develop a novel cell-culture system which makes it possible to communicate with cultured mammalian cells, bovine adrenal chromaffin cells were cultured on PPy-coated IT...

journal_title：Biomaterials

authors： Aoki T,Tanino M,Sanui K,Ogata N,Kumakura K

更新日期：1996-10-01 00:00:00

abstract：:Topographical features on the nanometer scale are known to influence cellular behavior. The response of specific cell types to various types of surface structures is currently still being investigated. Alumina ceramics play an important role as biomaterials, e.g., in medical and dental applications. In this study, we ...

journal_title：Biomaterials

authors： Wittenbrink I,Hausmann A,Schickle K,Lauria I,Davtalab R,Foss M,Keller A,Fischer H

更新日期：2015-09-01 00:00:00

abstract：:One of the potential factors that may affect the results of mesenchymal stem cell (MSC)-based therapy is the age of donors and recipients. However, there have been no controlled studies to investigate the influence of skeletal maturity on the MSC-based repair of cartilage. The purpose of this study was to compare the ...

journal_title：Biomaterials

authors： Shimomura K,Ando W,Tateishi K,Nansai R,Fujie H,Hart DA,Kohda H,Kita K,Kanamoto T,Mae T,Nakata K,Shino K,Yoshikawa H,Nakamura N

更新日期：2010-11-01 00:00:00

abstract：:The release rate of mercury from a conventional, a dispersed phase or a spherical high copper content amalgam under static conditions in stimulated or artificial saliva has been measured and found to decrease approximately exponentially with time. A higher initial release rate was observed for mercury in stimulated sa...

journal_title：Biomaterials

authors： Brune D

更新日期：1985-09-01 00:00:00

abstract：:Exosomes have emerged as appealing candidate therapeutic agents and delivery nanoplatforms due to their endogenous features and unique biological properties. However, obstacles such as low isolation yield, considerable complexity and potential safety concerns, and inefficient drug payload substantially hamper their th...

journal_title：Biomaterials

authors： Lu M,Huang Y

更新日期：2020-03-02 00:00:00

abstract：:Local signals from tissue-specific extracellular matrix (ECM) microenvironments, including matrix adhesive ligand, mechanical elasticity and micro-scale geometry, are known to instruct a variety of stem cell differentiation processes. Likewise, these signals converge to provide multifaceted, mechanochemical cues for h...

journal_title：Biomaterials

authors： Floren M,Tan W

更新日期：2015-08-01 00:00:00

abstract：:Collagen fibers are essential components of tissues, which are highly conserved across the animal kingdom and could be extremely useful in tissue engineering. The formation of these macromolecular fibers depends on molecular interactions-based self-assembly of the basic building blocks of collagen called tropocollagen...

journal_title：Biomaterials

authors： Krishnamoorthy N,Yacoub MH,Yaliraki SN

更新日期：2011-10-01 00:00:00

abstract：:Driven by the clinical need for a strong tissue adhesive with elastomeric material properties, a departure from legacy crosslinking chemistries was sought as a multipurpose platform for tissue mending. A fresh approach to bonding wet substrates has yielded a synthetic biomaterial that overcomes the drawbacks of free-r...

journal_title：Biomaterials

authors： Djordjevic I,Pokholenko O,Shah AH,Wicaksono G,Blancafort L,Hanna JV,Page SJ,Nanda HS,Ong CB,Chung SR,Chin AYH,McGrouther D,Choudhury MM,Li F,Teo JS,Lee LS,Steele TWJ

更新日期：2020-11-01 00:00:00

abstract：:Human (h) pluripotent stem cells (PSC) such as embryonic stem cells (ESC) can be directed into cardiomyocytes (CMs), representing a potential unlimited cell source for disease modeling, cardiotoxicity screening and myocardial repair. Although the electrophysiology of single hESC-CMs is now better defined, their multi-...

journal_title：Biomaterials

authors： Wang J,Chen A,Lieu DK,Karakikes I,Chen G,Keung W,Chan CW,Hajjar RJ,Costa KD,Khine M,Li RA

更新日期：2013-11-01 00:00:00

abstract：:Nanotherapeutics have been investigated for years, but only modest survival benefits were observed clinic. This is partially attributed to the short and rapid elimination of nanodrug after intravenous administration. In this study, a long circulation single wall carbon nanotube (SWCNT) complex was successfully fabrica...

journal_title：Biomaterials

authors： Xie L,Wang G,Zhou H,Zhang F,Guo Z,Liu C,Zhang X,Zhu L

更新日期：2016-10-01 00:00:00

abstract：:Bone defects caused by fractures or cancer-mediated destruction are debilitating. Chitosan is commonly used in scaffold matrices for bone healing, but rarely as a free drug. We demonstrate that free chitosan promotes osteoblast proliferation and osteogenesis in mesenchymal stem cells, increases osteopontin and collage...

journal_title：Biomaterials

authors： Tan ML,Shao P,Friedhuber AM,van Moorst M,Elahy M,Indumathy S,Dunstan DE,Wei Y,Dass CR

更新日期：2014-09-01 00:00:00

abstract：:Disruption of peripheral nerves due to trauma is a frequently occurring clinical problem. Gaps in the nerve are bridged by guiding the regenerating nerves along autologous grafts or artificial guides. This review gives an overview on the different methods of nerve repair techniques. Conventional suturing techniques ar...

journal_title：Biomaterials

authors： IJkema-Paassen J,Jansen K,Gramsbergen A,Meek MF

更新日期：2004-04-01 00:00:00

abstract：:Poly(epsilon-caprolactone) (PCL) was dissolved in four solvent systems, chloroform, tetrahydrofuran, acetone and ethyl acetate, and cast onto glass Petri dishes. The surface properties of the resulting films were investigated. The extent to which their properties were determined by the solvent used in each case was qu...

journal_title：Biomaterials

authors： Tang ZG,Black RA,Curran JM,Hunt JA,Rhodes NP,Williams DF

更新日期：2004-08-01 00:00:00

abstract：:Osteomyelitis characterized by an inflammatory response often leads to bone loss and the spread of bacterial infection to surrounding soft tissues. To overcome the side effects induced by the systemic antibiotic treatment for osteomyelitis, recent investigations have explored the use of antibiotic-loaded undegradable ...

journal_title：Biomaterials

authors： Peng KT,Chen CF,Chu IM,Li YM,Hsu WH,Hsu RW,Chang PJ

更新日期：2010-07-01 00:00:00

abstract：:The systemic administration of immunosuppressive and anti-inflammatory drugs is routinely employed in organ transplantation to minimize graft rejection and improve graft survival. Localized drug delivery has the potential to improve transplant outcomes by providing sustained exposure to efficacious drug concentrations...

journal_title：Biomaterials

authors： Chang CA,Akinbobuyi B,Quintana JM,Yoshimatsu G,Naziruddin B,Kane RR

更新日期：2018-03-01 00:00:00

abstract：:The aminohexyl derivative of the copolymer of 2-hydroxyethyl methacrylate and ethylene dimethacrylate (p(HEMA)-Hex) in the form of regular spherical particles was used as a polymeric carrier for chemically sorbed methotrexate (MTX). The effect of the washed p(HEMA)-Hex-MTX carrier on the morphological structure of don...

journal_title：Biomaterials

authors： Horák D,Svec F,Adamyan A,Titova M,Skuba N,Voronkova O,Trostenyuk N,Vishnevskii V,Gumargalieva K

更新日期：1992-01-01 00:00:00