Effect of indomethacin on intestinal water transport in salmonella-infected rhesus monkeys.

abstract：:Vibrio cholerae normally inhabits aquatic habitats but can cause a severe diarrheal illness in humans. Its arsenal of virulence factors includes a secreted hemagglutinin (HA) protease. An HA protease-deficient mutant of V. cholerae was isolated and designated E7946 mpc. E7946 mpc was found to contain a point mutation ...

journal_title：Infection and immunity

authors： Vance RE,Zhu J,Mekalanos JJ

更新日期：2003-05-01 00:00:00

abstract：:Yersinia pestis causes bubonic, pneumonic, and septicemic plague, diseases that are rapidly lethal to most mammals, including humans. Plague develops as a consequence of bacterial neutralization of the host's innate immune response, which permits uncontrolled growth and causes the systemic hyperactivation of the infla...

journal_title：Infection and immunity

authors： Dhariwala MO,Olson RM,Anderson DM

更新日期：2017-10-18 00:00:00

abstract：:Salmonella enterica serovar Enteritidis is a major cause of food-borne diseases associated with consumption of shell eggs. Clinical isolates of S. enterica serovar Enteritidis exhibit a wide spectrum of virulence in mice. A highly virulent isolate (SE2472) was previously shown to be more resistant in vitro than other ...

journal_title：Infection and immunity

authors： Lu S,Killoran PB,Fang FC,Riley LW

更新日期：2002-02-01 00:00:00

abstract：:We studied interleukin-1 (IL-1) secretion by rat peritoneal exudate macrophages stimulated with purified toxic shock syndrome toxin-1 (TSST-1). TSST-1 was observed to be a more potent inducer of IL-1 than was endotoxin. The induction of IL-1 secretion by TSST-1 was not blocked by polymyxin B but could be blocked by mo...

journal_title：Infection and immunity

authors： Beezhold DH,Best GK,Bonventre PF,Thompson M

更新日期：1987-12-01 00:00:00

abstract：:A dextranase preparation (AD17) partially purified from a culture liquor of Spicaria violacea strain IFO 6120 significantly inhibited the formation of artifcial dental plaque on a steel wire or on an extracted tooth surface. Changes in the surface morphology of Streptococcus mutans cells due to AD17 action were studie...

journal_title：Infection and immunity

authors： Hamada S,Mizuno J,Murayama Y,Ooshima Y,Masuda N

更新日期：1975-12-01 00:00:00

abstract：:By using a suckling mouse assay, heat-stable enterotoxin (ST) was purified from the culture filtrate of Yersinia enterocolitica isolated from a diarrheal patient. The purification procedures involve ultrafiltration with an Amicon HIP-10 hollow fiber, ethanol fractionation, protamine sulfate treatment, diethylaminoethy...

journal_title：Infection and immunity

authors： Okamoto K,Inoue T,Ichikawa H,Kawamoto Y,Miyama A

更新日期：1981-02-01 00:00:00

abstract：:Spleen cell cultures from guinea pigs given legionella pneumophila vaccine in complete Freund adjuvant or as a sublethal infection were inhibited in their migration activity in vitro when incubated with specific antigen. Both direct and indirect migration inhibition assays revealed sensitization of the guinea pigs to ...

journal_title：Infection and immunity

authors： Friedman H,Widen R,Lee I,Klein T

更新日期：1983-09-01 00:00:00

abstract：:The virulence of Neisseria gonorrhoeae for chicken embryos can be modified in a predictable manner by the addition of microbial siderophores to the inoculum. "Meningobactin" and "gonobactin," siderophores isolated from iron-limited cultures of meningococci and gonococci, respectively, enhance the virulence of the rela...

journal_title：Infection and immunity

authors： Finkelstein RA,Yancey RJ

更新日期：1981-05-01 00:00:00

abstract：:Hydrogen sulfide (H(2)S) is a major metabolic end product detected in deep periodontal pockets that is produced by resident periodontopathic microbiota associated with the progression of periodontitis. Treponema denticola, a member of the subgingival biofilm at disease sites, produces cystalysin, an enzyme that catabo...

journal_title：Infection and immunity

authors： Chu L,Dong Z,Xu X,Cochran DL,Ebersole JL

更新日期：2002-03-01 00:00:00

abstract：:Escherichia coli isolates from patients with bacteriuria of pregnancy were compared by PCR with isolates from patients with community-acquired cystitis for the presence of established virulence determinants. The strains from patients with bacteriuria of pregnancy were less likely to carry genes for P-family, S-family,...

journal_title：Infection and immunity

authors： Graham JC,Leathart JB,Keegan SJ,Pearson J,Bint A,Gally DL

更新日期：2001-02-01 00:00:00

abstract：:Gram-negative bacterial pathogens utilize virulence-associated secretion systems to inject, or translocate, effector proteins into host cells to manipulate cellular processes and promote bacterial replication. However, translocated bacterial products are sensed by nucleotide binding domain and leucine-rich repeat-cont...

journal_title：Infection and immunity

authors： Zwack EE,Feeley EM,Burton AR,Hu B,Yamamoto M,Kanneganti TD,Bliska JB,Coers J,Brodsky IE

更新日期：2017-09-20 00:00:00

abstract：:Expression of ace (adhesin to collagen of Enterococcus faecalis), encoding a virulence factor in endocarditis and urinary tract infection models, has been shown to increase under certain conditions, such as in the presence of serum, bile salts, urine, and collagen and at 46 °C. However, the mechanism of ace/Ace regula...

journal_title：Infection and immunity

authors： Roh JH,Singh KV,La Rosa SL,Cohen AL,Murray BE

更新日期：2015-01-01 00:00:00

abstract：:The results of this study show that recombinant interleukin-8 (IL-8) enhances the intracellular killing of Mycobacterium fortuitum by human granulocytes. This chemokine did not stimulate the phagocytosis of M. fortuitum by granulocytes at various bacterium-to-cell ratios. The killing process was not affected by the NA...

journal_title：Infection and immunity

authors： Nibbering PH,Pos O,Stevenhagen A,Van Furth R

更新日期：1993-08-01 00:00:00

abstract：:The yields of exotoxin A in Pseudomonas aeruginosa cultures were influenced by the concentration of iron in the culture media. When the iron concentration of the culture media was increased from 0.05 to 1.5 microgram/ml, there was at least a 90% decrease in exotoxin A (measured both by enzymatic activity and by mouse ...

journal_title：Infection and immunity

authors： Bjorn MJ,Iglewski BH,Ives SK,Sadoff JC,Vasil ML

更新日期：1978-03-01 00:00:00

abstract：:Vitamin D is an important regulator of the expression of antimicrobial peptides, and vitamin D deficiency is associated with respiratory infections. Regulating expression of antimicrobial peptides, such as the human cathelicidin antimicrobial peptide 18 (hCAP18)/LL-37, by vitamin D in bronchial epithelial cells requir...

journal_title：Infection and immunity

authors： Schrumpf JA,van Sterkenburg MA,Verhoosel RM,Zuyderduyn S,Hiemstra PS

更新日期：2012-12-01 00:00:00

abstract：:Neutrophils are the main inflammatory cell present in lesions involving the central nervous system (CNS) during human and murine listeriosis. In this study, administration of the neutrophil-depleting monoclonal antibody RB6-8C5 during experimental murine listeriosis facilitated the multiplication of Listeria monocytog...

journal_title：Infection and immunity

authors： López S,Marco AJ,Prats N,Czuprynski CJ

更新日期：2000-08-01 00:00:00

abstract：:The chromosomal iroBCDEN gene cluster first described for Salmonella enterica is involved in the uptake of catecholate-type siderophore compounds. An orthologous gene cluster has recently been detected in Escherichia coli strains which cause extraintestinal disease. This E. coli iroBCDEN gene cluster has an impact on ...

journal_title：Infection and immunity

authors： Sorsa LJ,Dufke S,Heesemann J,Schubert S

更新日期：2003-06-01 00:00:00

abstract：:Leishmaniae are protozoans which, depending upon both the host and parasite species, can cause either a healing or nonhealing infection. While C57BL/10 mice are able to heal following infection with Leishmania major, they fail to heal following infection with Leishmania amazonensis. In order to address the role of Th1...

journal_title：Infection and immunity

authors： Afonso LC,Scott P

更新日期：1993-07-01 00:00:00

abstract：:Antimicrobial peptides (AMPs), such as β-defensins and cathelicidins, are essential components of innate and adaptive immunity owing to their extensive multifunctional activities. However, their role in fungal infection in vivo remains elusive. In this study, we investigated the protective effect of murine β-defensin ...

journal_title：Infection and immunity

authors： Kolar SS,Baidouri H,Hanlon S,McDermott AM

更新日期：2013-08-01 00:00:00

abstract：:Group A streptococci isolated from skin adhere in greater numbers to human skin epithelial cells than to cells obtained from buccal mucosa whereas streptococci isolated from a throat tend to adhere in greater numbers to buccal epithelial cells than to skin epithelial cells in vitro. M protein-producing strains of grou...

journal_title：Infection and immunity

authors： Alkan M,Ofek I,Beachey EH

更新日期：1977-11-01 00:00:00

abstract：:YopE is a virulence factor that is secreted into host cells infected by Yersinia species. The YopE C-terminal domain has GTPase-activating protein (GAP) activity. The YopE N-terminal domain contains an epitope that is an immunodominant CD8(+) T cell antigen during primary infection of C57BL/6 mice with Yersinia pseudo...

journal_title：Infection and immunity

authors： Zhang Y,Mena P,Romanov G,Bliska JB

更新日期：2014-07-01 00:00:00

abstract：:Calprotectin, an S100 calcium-binding protein with broad-spectrum antimicrobial activity in vitro, is expressed in neutrophils, monocytes, and gingival keratinocytes. In periodontitis, calprotectin appears upregulated and is detected at higher levels in gingival crevicular fluid and tissue specimens. How calprotectin ...

journal_title：Infection and immunity

authors： Nisapakultorn K,Ross KF,Herzberg MC

更新日期：2001-07-01 00:00:00

abstract：:V beta 10(+) and V beta 14(+) T cells were selectively increased 7 to 14 days following infection in the lungs of naive mice infected with Histoplasma capsulatum. Following secondary challenge of immune mice, V beta 1(+) and V beta 8.1(+) cells were sporadically increased. Elimination of V beta 10(+) and V beta 14(+) ...

journal_title：Infection and immunity

authors： Deepe GS Jr,Gibbons RS,Ward SR

更新日期：2002-03-01 00:00:00

abstract：:Otitis media developed in 67% of chinchillas inoculated intranasally with type 7 Streptococcus pneumoniae and influenza A virus. Only 4% of chinchillas inoculated with influenza alone and 21% of chinchillas inoculated with S. pneumoniae alone developed otitis media. Among the chinchillas that developed otitis media af...

journal_title：Infection and immunity

authors： Giebink GS,Berzins IK,Marker SC,Schiffman G

更新日期：1980-11-01 00:00:00

abstract：:Protection against cholera has been correlated with the level of serum vibriocidal antibodies. The specificity of these vibriocidal antibodies was mostly to the lipopolysaccharide (LPS). We synthesized conjugates of detoxified LPS with cholera toxin (CT) and other proteins in order to elicit serum LPS antibodies with ...

journal_title：Infection and immunity

authors： Gupta RK,Szu SC,Finkelstein RA,Robbins JB

更新日期：1992-08-01 00:00:00

abstract：:We found that serum samples from patients with different clinical forms of American cutaneous leishmaniasis (ACL) contained immunoglobulin G and immunoglobulin M antibodies which reacted with laminin but not with various other purified connective tissue components, such as collagen types I, III, IV, and V and fibronec...

journal_title：Infection and immunity

authors： Avila JL,Rojas M,Rieber M

更新日期：1984-01-01 00:00:00

abstract：:The host immune response plays an important role in the onset and progression of cerebral malaria (CM). The complement system is an essential component of the innate immune response to malaria, and its activation generates the anaphylatoxin C5a. To test the hypothesis that C5a signaling contributes to the pathogenesis...

journal_title：Infection and immunity

authors： Kim H,Erdman LK,Lu Z,Serghides L,Zhong K,Dhabangi A,Musoke C,Gerard C,Cserti-Gazdewich C,Liles WC,Kain KC

更新日期：2014-01-01 00:00:00

abstract：:Two glucosyltransferase genes from Streptococcus mutans GS-5, gtfB and gtfC, have been previously isolated and sequenced in this laboratory. In the present communication a third gtf gene, gtfD, was isolated and characterized. Isolation of the gene involved a novel procedure utilizing the integration plasmid pVA891. A ...

journal_title：Infection and immunity

authors： Hanada N,Kuramitsu HK

更新日期：1989-07-01 00:00:00

abstract：:Shiga toxin-producing Escherchia coli (STEC) comprises a group of attaching and effacing (A/E) enteric pathogens of animals and humans. Natural and experimental infection of calves with STEC may result in acute enteritis or subclinical infection, depending on serotype- and host-specific factors. To quantify intestinal...

journal_title：Infection and immunity

authors： Stevens MP,Marchès O,Campbell J,Huter V,Frankel G,Phillips AD,Oswald E,Wallis TS

更新日期：2002-02-01 00:00:00

abstract：:Free lipid A of Bordetella pertussis, Neisseria meningitidis, and Escherichia coli lipopolysaccharide (LPS) was prepared by hydrolysis in acetate buffer (pH 4.5); in addition, lipid A from B. pertussis and E. coli was prepared by hydrolysis in mineral acid (HCl). The precipitates obtained were purified by extraction m...

journal_title：Infection and immunity

authors： Caroff M,Cavaillon JM,Fitting C,Haeffner-Cavaillon N

更新日期：1986-11-01 00:00:00