The toxic and teratogenic effects of selected organophosphorus compounds on the embryos of three species of amphibians.

Abstract:

:The toxic and teratogenic effects of 4 organophosphorus compounds (phenyl saliginen cyclic phosphate (PSCP), leptophos-oxon (LPTO), tri-o-tolyl phosphate (TOTP), and paraoxon (PXN] were investigated in the embryos of 3 species of frogs. Developmental abnormalities were observed in surviving embryos of each of the 3 species following exposure to PSCP at concentrations as low as 500 ppb for 24 h. LPTO, while being toxic to gray treefrog embryos at concentrations as low as 2.2 ppm, did not induce developmental abnormalities. TOTP and PXN were neither toxic nor teratogenic at concentrations of 10 ppm and 100 ppm respectively.

journal_name

Toxicol Lett

journal_title

Toxicology letters

authors

Fulton MH,Chambers JE

doi

10.1016/0378-4274(85)90163-8

subject

Has Abstract

pub_date

1985-08-01 00:00:00

pages

175-80

issue

2-3

eissn

0378-4274

issn

1879-3169

pii

0378-4274(85)90163-8

journal_volume

26

pub_type

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