Abstract:
:The effect of oligosaccharide carrying lipids on membrane fluidity has been investigated. Gangliosides GM1 and GQ1 were reconstituted into phosphatidylcholine bilayer membranes at low concentrations (less than 5 mol%). A strong fluidizing effect was observed leading to a suppression of the phase transition temperature. This was most pronounced with highly sialylated gangliosides. Ca2+ reverses the effect due to phase separation phenomena. We assume a hydrophilic lipid-lipid interaction in accordance with previously studied glycoprotein-lipid interactions.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Ollmann M,Galla HJdoi
10.1016/0014-5793(85)80214-3subject
Has Abstractpub_date
1985-01-01 00:00:00pages
173-6issue
1eissn
0014-5793issn
1873-3468pii
0014-5793(85)80214-3journal_volume
179pub_type
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