In vitro studies on microphage functions in chronic pyoderma vegetans.

abstract：:The penetration and permeation of the recombinant protein plasminogen activator inhibitor type 2 (PAI-2) in two formulations, one containing a penetration enhancer, into the psoriatic and uninvolved skin of eight patients with plaque-type psoriasis were investigated. Penetration and permeation of PAI-2 were measured b...

journal_title：Archives of dermatological research

authors： Gould AR,Sharp PJ,Smith DR,Stegink AJ,Chase CJ,Kovacs JC,Penglis S,Chatterton BE,Bunn CL

更新日期：2003-11-01 00:00:00

abstract：:This study was designed to investigate the proliferative activity of the buccal mucosa in healthy adult persons with regard to individual age. Punch biopsy specimens were taken from the buccal mucosa of 19 individuals (10 females, 9 males) ranging in age from 24 to 80 years, and were then examined autoradiographically...

journal_title：Archives of dermatological research

authors： Maidhof R,Hornstein OP

更新日期：1979-06-25 00:00:00

abstract：:The function of microphages has been studied in two patients with chronic pyoderma vegetans by in vitro determination of phagocytosis as well as chemotaxis. The results showed a striking decrease in the chemotactic activity of the neutrophil granulocytes, a reduced phagocytosis of Candida albicans and Staphylococcus a...

journal_title：Archives of dermatological research

authors： Djawari D,Hornstein OP

更新日期：1978-09-28 00:00:00

abstract：:In this study, a new procedure for the cultivation of dermal vascular endothelial cells from guinea pig ear lobe was established, and specific binding of [3H]mepyramine to the cultured cell membranes was demonstrated. The vascular endothelial cells were successfully isolated from the dermis of guinea pig ear lobes by ...

journal_title：Archives of dermatological research

authors： Noso N,Hide M,Nakamura K,Yamamoto S

更新日期：1990-01-01 00:00:00

abstract：:The adenylate cyclase system of an established human trichilemmoma cell line was investigated. Stimulators of human epidermal adenylate cyclase system, epinephrine, histamine, adenosine, and prostaglandin E increased cyclic AMP levels of the trichilemmoma cells. The effects of epinephrine, histamine, and adenosine wer...

journal_title：Archives of dermatological research

authors： Tsutsui M,Iizuka H,Ohkawara A,Adachi K,Kanzaki T

更新日期：1987-01-01 00:00:00

abstract：:The distribution of several markers of keratinocyte differentiation was studied in normal epidermis, basal cell carcinomas (BCCs), and squamous cell carcinomas (SCCs) using the immunoperoxidase technique on frozen sections of punch biopsy specimens. As markers a panel of chain-specific monoclonal antibodies (MoAbs) di...

journal_title：Archives of dermatological research

authors： Lavrijsen AP,Tieben LM,Ponec M,van der Schroeff JG,van Muijen GN

更新日期：1989-01-01 00:00:00

abstract：:Previous studies showed an association between various dermatological diseases and epicardial fat thickness (EFT). However, EFT, which has been accepted as a cardiometabolic risk factor in recent years, has not been studied in the context of hidradenitis suppurativa (HS). Therefore, we aimed to determine whether EFT i...

journal_title：Archives of dermatological research

authors： Alatas ET,Biteker M,Alatas OD

更新日期：2020-09-01 00:00:00

abstract：:Localized scleroderma (LoSc) is rare connective tissue disease that manifests with inflammation and fibrosis of the skin. Depending on the LoSc subtype, adjacent structures such as subcutaneous tissue, fascia, muscles, bones may be affected. The hallmark of fibrosis is tissue remodelling with excess deposition of extr...

journal_title：Archives of dermatological research

authors： Wolska-Gawron K,Bartosińska J,Krasowska D

更新日期：2020-07-01 00:00:00

abstract：:Staphylococcus aureus is a common wound-infecting organism which can interact with cells via the extracellular matrix protein fibronectin (FN). The aim of this study was to determine the effect of the FN-binding protein (FnBP) of S. aureus on the behaviour of a human skin keratinocytes cell line (UP). FN-coated plates...

journal_title：Archives of dermatological research

authors： Kintarak S,Nair SP,Speight PM,Whawell SA

更新日期：2004-11-01 00:00:00

abstract：:Thymocyte selection-associated high-mobility group box (TOX) is aberrantly expressed in cutaneous T-cell lymphomas. In a recent study, TOX expression was noted unexpectedly in the follicle center (germinal center) B-cells of reactive lymph nodes and tonsils, used as external controls. To evaluate whether TOX is also e...

journal_title：Archives of dermatological research

authors： Schrader AM,Jansen PM,Willemze R

更新日期：2016-08-01 00:00:00

abstract：:The fetal development of Merkel cells-neuroendocrine cells of the skin - has been a matter of debate for a long time. Recent results have helped to confirm their intraepidermal development in humans. Simple epithelial cytokeratins (CK) nos. 8, 18, 19 and 20 are well established markers at the light microscopic level. ...

journal_title：Archives of dermatological research

authors： Moll I,Zieger W,Schmelz M

更新日期：1996-04-01 00:00:00

abstract：:The cellular DNA ploidy of 30 cases of malignant melanoma was measured by 4',6-diamidino-2-phenylindole-DNA (DAPI-DNA) microfluorometry. DNA histograms and DNA index values were compared among melanomas of different cell morphology. Epithelioid cell melanomas often showed greater DNA aneuploidy than spindle cell melan...

journal_title：Archives of dermatological research

authors： Chi HI,Uyeda Y,Umebayashi Y,Otsuka F

更新日期：1993-01-01 00:00:00

abstract：:Based on reports suggesting aberrant cell-mediated immunity and altered infiltration of immunocompetent cells into the skin in psoriasis, we studied the stimulation of T cells by autologous non-T mononuclear leukocytes (autologous mixed lymphocyte reaction, AMLR) and by epidermal cells isolated from lesional and clini...

journal_title：Archives of dermatological research

authors： Schopf RE,Hoffmann A,Jung M,Morsches B,Bork K

更新日期：1986-01-01 00:00:00

abstract：:When determined in vitro, the SPF of certain commercial sunscreen products can be lower than the SPF indicated on the label. The study of the composition of this type of product enabled us to note that the majority contained substances reputed to have anti-inflammatory properties. This effect is shown by inhibiting th...

journal_title：Archives of dermatological research

authors： Couteau C,Chauvet C,Paparis E,Coiffard LJ

更新日期：2012-12-01 00:00:00

abstract：:Three per cent boric acid incorporated in an anhydrous, water-emulsifying ointment causes no increase of boron levels in blood and urine during a period of 1-9 days after a single topical application. The same amount of boric acid incorporated in a water-based jelly does cause an increase in blood and urine levels, be...

journal_title：Archives of dermatological research

authors： Stüttgen G,Siebel T,Aggerbeck B

更新日期：1982-01-01 00:00:00

abstract：:The goal of this study is to investigate commercially available cosmetics (foundations, skin care creams) which also claim to include a sun protection factor (SPF). Are these products, which are not considered sunscreen products, helpful or could they be harmful? Using an in vitro method, we tested the effectiveness o...

journal_title：Archives of dermatological research

authors： Séhédic D,Hardy-Boismartel A,Couteau C,Coiffard LJ

更新日期：2009-09-01 00:00:00

abstract：:We investigated the effect of interferon-gamma (IFN-gamma) on skin equivalents. Keratinocytes from involved and uninvolved skin from psoriatic subjects and from healthy subjects were grown on preproduced dermal equivalents (DE) containing fibroblasts from healthy skin or psoriatic lesions. Healthy keratinocytes were a...

journal_title：Archives of dermatological research

authors： Fransson J,Shen Q,Scheynius A,Hammar H

更新日期：1996-12-01 00:00:00

abstract：:Vitiligo is an acquired clinical conundrum, characterized by white areas on the skin due to loss of functional melanocytes. Various studies demonstrated that vitiligo is associated with fewer risk of skin cancer but no exact molecular explanation for this interesting observation has been described. This article review...

journal_title：Archives of dermatological research

authors： Feily A,Pazyar N

更新日期：2011-11-01 00:00:00

abstract：:Glycerol, widely used as humectant, is known to protect against irritants and to accelerate recovery of irritated skin. However, most studies were done with topical formulations (i.e. emulsions) containing glycerol in relatively high amounts, preventing drawing conclusions from direct effects. In this study, acute che...

journal_title：Archives of dermatological research

authors： Atrux-Tallau N,Romagny C,Padois K,Denis A,Haftek M,Falson F,Pirot F,Maibach HI

更新日期：2010-08-01 00:00:00

abstract：:Langerhans cells appear to be critical for IgE-mediated allergen capture and presentation in human atopic dermatitis. The present study sought to determine whether epidermal (i.e Langerhans cells) and dermal dendritic cells in the skin of dogs with atopic dermatitis are hyperplastic and expressed surface IgE. Frozen s...

journal_title：Archives of dermatological research

authors： Olivry T,Moore PF,Affolter VK,Naydan DK

更新日期：1996-09-01 00:00:00

abstract：:Enhanced susceptibility to viral infections has been reported repeatedly in atopic dermatitis (AD). A difference in the capacity to produce interferons (IFN) in response to viral antigens may be the cause. In the present study we investigated the in vitro IFN production of leukocytes from AD patients in response to di...

journal_title：Archives of dermatological research

authors： Kapp A,Gillitzer R,Kirchner H,Schöpf E

更新日期：1987-01-01 00:00:00

abstract：:This study probes the extent of coupling between the reversal of epidermal hyperproliferation induced by essential fatty acid (EFA) deficiency in guinea pigs, the hydrolysis of epidermal phosphatidylinositol 4,5-bisphosphate (PtdIns4,5P2), and the rapid formation of inositol triphosphate (InsP3). Our data revealed tha...

journal_title：Archives of dermatological research

authors： Tang W,Ziboh VA

更新日期：1988-01-01 00:00:00

abstract：:The injured skin produces a number of mediators that directly or indirectly modulate cell chemotaxis, migration, proliferation, and angiogenesis. Components of the kinin pathway including the kinin B1 receptor (B1R) have been found to occur in the human skin, but information about its role on keratinocyte biology is s...

journal_title：Archives of dermatological research

authors： Mejia AJ,Matus CE,Pavicic F,Concha M,Ehrenfeld P,Figueroa CD

更新日期：2015-11-01 00:00:00

abstract：:Myotonic muscular dystrophy (MMD) is caused by an abnormal function of RNA-binding proteins (RBP) resulting in DNA spliceopathy. A case of a patient, with MMD multiple basal and squamous cell carcinomas and dysplastic nevi, is described. The association between MMD and non-melanoma skin cancer has been reported before...

journal_title：Archives of dermatological research

authors： Zemtsov A

更新日期：2010-04-01 00:00:00

abstract：:The effects of acidic and basic fibroblast growth factors (aFGF and bFGF, respectively) on proliferation and differentiation of cultured hair apparatus cells were examined using bovine pituitary extract (BPE)-free media. The importance of FGFs as growth factors in BPE was also examined. Both FGFs and BPE stimulated ce...

journal_title：Archives of dermatological research

authors： Tanigaki-Obana N,Ito M

更新日期：1994-01-01 00:00:00

abstract：:The mechanistic target of rapamycin (mTOR) is involved in the regulation of cellular growth, proliferation, lipid synthesis, and protein translation. The mTOR pathway involves two complexes: the mechanistic target of rapamycin complex 1 (mTORC1) and the mechanistic target of rapamycin complex 2 (mTORC2). Both mTOR com...

journal_title：Archives of dermatological research

authors： Leo MS,Sivamani RK

更新日期：2014-12-01 00:00:00

abstract：:Splenopentin (SP-5: Arg-Lys-Glu-Val-Tyr), a pentapeptide corresponding to the residues 32-36 of the splenic hormone splenin, increases dose-dependently the number of bone marrow colonies (M and GM colonies). Therefore, we tested the stimulatory effect of SP-5 on the recruitment of epidermal Langerhans cells in skin de...

journal_title：Archives of dermatological research

authors： Gruner S,Diezel W,Strunk D,Zwirner A,Sönnichsen N,Anhalt GJ

更新日期：1990-01-01 00:00:00

abstract：:Marie Unna Hereditary Hypotrichosis 1 (MUHH1; OMIM 146550), a rare monogenic condition characterized by the development of sparse, twisted hair or complete hair loss, is the consequence of mutations located in the hairless (HR) gene. We have identified a 68-year-old Hungarian woman affected by alopecia universalis and...

journal_title：Archives of dermatological research

authors： Farkas K,Nagy N,Kinyó A,Kemény L,Széll M

更新日期：2012-10-01 00:00:00

abstract：:Sphingosylphosphorylcholine (SPC) has been reported to stimulate wound healing by its potent mitogenic effect. Fibronectin (FN) is a cell-adhesion protein that plays an important role in cell migration and collagen deposition during wound healing. In order to elucidate further the mechanism involved in the accelerated...

journal_title：Archives of dermatological research

authors： Suhr KB,Tsuboi R,Seo EY,Piao YJ,Lee JH,Park JK,Ogawa H

更新日期：2003-01-01 00:00:00

abstract：:Vitiliginous patients undergoing photochemotherapy with TMP were less susceptible to a sun burn. To investigate this point, the MED for UV-B was measured before, 2 h, and 24 h after oral intake of TMP in 10 healthy volunteers. There was an increase of MED when UV exposure had taken place 2 h after TMP intake (P < 0.01...

journal_title：Archives of dermatological research

authors： Agache PG,Coupez L

更新日期：1980-01-01 00:00:00