Spontaneous abortions and malformations in the offspring of nurses exposed to anaesthetic gases, cytostatic drugs, and other potential hazards in hospitals, based on registered information of outcome.

Abstract:

:Nurses working in selected departments of general hospitals in Finland were collected from a central register on health personnel in Finland. Using the Hospital Discharge Register and the Register of Congenital Malformations, case nurses were selected who had had a spontaneous abortion (N = 217) or a malformed child (N = 46) between the years 1973 and 1979. Controls consisted of three nurses who had had a normal birth; the control nurses were matched for age and hospital of employment. Information on exposure in the first trimester of pregnancy was sought through the head nurses of the hospitals. No significant increase in risk of spontaneous abortion or of malformation was observed after exposure to anaesthetic gases (odds ratio for spontaneous abortion 1.2), sterilising gases and soaps, or x-rays. Handling of cytostatic drugs did not affect the frequency of spontaneous abortion but was associated with malformations in the offspring. The odds ratio, based on eight cases, was 4.7 (p = 0.02) when the logistic model was adopted. The results suggest that the exposures investigated, other than cytostatic drugs, do not cause a strong reproductive risk. Further studies are needed, particularly on cytostatic drugs.

authors

Hemminki K,Kyyrönen P,Lindbohm ML

doi

10.1136/jech.39.2.141

subject

Has Abstract

pub_date

1985-06-01 00:00:00

pages

141-7

issue

2

eissn

0143-005X

issn

1470-2738

journal_volume

39

pub_type

杂志文章
  • Birth weight is inversely associated with coronary heart disease in post-menopausal women: findings from the British women's heart and health study.

    abstract:OBJECTIVES:(1) To assess the association between birth weight and coronary heart disease (CHD) risk in a cohort of post-menopausal women, (2) to determine the combined effects of birth weight and adult body mass index on CHD, (3) to assess the role of insulin resistance as a mediating factor in the associations. DESIG...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.58.2.120

    authors: Lawlor DA,Davey Smith G,Ebrahim S

    更新日期:2004-02-01 00:00:00

  • Coronary artery bypass graft surgery: socioeconomic inequalities in access and in 30 day mortality. A population-based study in Rome, Italy.

    abstract:OBJECTIVES:To evaluate whether coronary artery bypass graft (CABG) surgery is equally provided among different socioeconomic status (SES) groups in accordance with need. To estimate the association between SES and mortality occurring 30 days after CABG surgery. DESIGN:Individual socioeconomic index assigned with respe...

    journal_title:Journal of epidemiology and community health

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1136/jech.54.12.930

    authors: Ancona C,Agabiti N,Forastiere F,Arcà M,Fusco D,Ferro S,Perucci CA

    更新日期:2000-12-01 00:00:00

  • Impact of the 2008 global financial crisis on the health of Canadians: repeated cross-sectional analysis of the Canadian Community Health Survey, 2007-2013.

    abstract:BACKGROUND:Despite a clear impact on the Canadian economy, little is known about the subsequent health impacts of the 2008 global financial crisis (GFC) in this country. This study fills this gap in knowledge by conducting a repeated cross-sectional analysis of the Canadian Community Health Survey (CCHS). METHODS:Data...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2016-207661

    authors: Nour S,Labonté R,Bancej C

    更新日期:2017-04-01 00:00:00

  • Assessing the validity of recent estimates of problematic drug use in England.

    abstract:BACKGROUND:The Home Office has recently published estimates which, for the first time, provide a "robust national estimate" of the number of problematic drug users in England. The 2004/05 and 2005/06 estimates are the highest estimates ever produced for England and coincide with the highest ever government annual expen...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.2008.076844

    authors: Frisher M,Forsyth A

    更新日期:2009-01-01 00:00:00

  • Housing and respiratory health at older ages.

    abstract:BACKGROUND:A large proportion of the population of England live in substandard housing. Previous research has suggested that poor-quality housing, particularly in terms of cold temperatures, mould, and damp, poses a health risk, particularly for older people. The present study aimed to examine the association between h...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2012-201458

    authors: Webb E,Blane D,de Vries R

    更新日期:2013-03-01 00:00:00

  • External validation, repeat determination, and precision of risk estimation in misclassified exposure data in epidemiology.

    abstract:STUDY OBJECTIVE:The aim was to quantify the difference in precision of risk estimates in epidemiology between the situations where misclassification of exposure is corrected for by external validation and where it is corrected for by internal repeat measurement. Precision was measured in terms of the expected width of ...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.46.6.620

    authors: Duffy SW,Maximovitch DM,Day NE

    更新日期:1992-12-01 00:00:00

  • Seroconversion and seroreversion in IgG antibodies to Helicobacter pylori: a serology based prospective cohort study.

    abstract:STUDY OBJECTIVES:To assess the incidence of seroconversion and seroreversion in IgG antibodies to Helicobacter pylori within a 11 year observation period using these events as markers for acquisition and loss of the infection, respectively. DESIGN:Population based prospective cohort study. SETTING:Northern part of Co...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.54.6.444

    authors: Rosenstock S,Jørgensen T,Andersen L,Bonnevie O

    更新日期:2000-06-01 00:00:00

  • Induced abortions, miscarriages, and tobacco smoking as risk factors for secondary infertility.

    abstract:STUDY OBJECTIVE:The aim was to determine whether induced abortions could increase the risk of secondary infertility. DESIGN:This was a case-control study; cases were women with secondary infertility, individually matched to two controls who were currently pregnant. Each participant was interviewed by one of two medica...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.47.1.36

    authors: Tzonou A,Hsieh CC,Trichopoulos D,Aravandinos D,Kalandidi A,Margaris D,Goldman M,Toupadaki N

    更新日期:1993-02-01 00:00:00

  • Social influences on trajectories of self-rated health: evidence from Britain, Germany, Denmark and the USA.

    abstract:BACKGROUND:This study investigates social inequalities in self-rated health dynamics for working-aged adults in four nations, representing distinct welfare regime types. The aims are to describe average national trajectories of self-rated health over a 7-year period, identify social determinants of cross-sectional and ...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.2009.091199

    authors: Sacker A,Worts D,McDonough P

    更新日期:2011-02-01 00:00:00

  • Association of age and social class with suicide among men in Great Britain.

    abstract:STUDY OBJECTIVE:The aim was to investigate suicide and "undetermined" deaths by age, economic activity status, and social class in Great Britain among males of working age. DESIGN:The study was a cross sectional analysis of Registrar General's data for England and Wales around 1981, repeated for around 1971, and for S...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.45.3.195

    authors: Kreitman N,Carstairs V,Duffy J

    更新日期:1991-09-01 00:00:00

  • Leukaemia and childhood cancer in twins.

    abstract::Data from the United Kingdom on childhood leukaemia and childhood cancer in twins and from the United States on leukaemia in twins are analysed by a new method. The method distinguishes determinants occurring before the stage of pregnancy corresponding with the cleavage of MZ pairs, from determinants occurring after t...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.38.1.12

    authors: Knox EG,Marshall T,Barling R

    更新日期:1984-03-01 00:00:00

  • Using 'amenable mortality' as indicator of healthcare effectiveness in international comparisons: results of a validation study.

    abstract:BACKGROUND AND STUDY AIMS:There is widespread consensus on the need for better indicators of the effectiveness of healthcare. We carried out an analysis of the validity of amenable mortality as an indicator of the effectiveness of healthcare, focusing on the potential use in routine surveillance systems of between-coun...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2012-201471

    authors: Mackenbach JP,Hoffmann R,Khoshaba B,Plug I,Rey G,Westerling R,Pärna K,Jougla E,Alfonso J,Looman C,McKee M

    更新日期:2013-02-01 00:00:00

  • Prognosis of falls in old people at home.

    abstract::One hundred and twenty-five people aged 65 and over in the Birmingham area who fell at home were followed up for one year after the fall had been reported by the general practitioner. They were compared with 125 control subjects matched for age and sex and drawn from the same doctors' lists. Two months after the fall,...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.35.3.200

    authors: Wild D,Nayak US,Isaacs B

    更新日期:1981-09-01 00:00:00

  • Insulin treated diabetes mellitus: causes of death determined from record linkage of population based registers in Leicestershire, UK.

    abstract:STUDY OBJECTIVE:Analyses of causes of mortality in people with diabetes using data form death certificates mentioning diabetes provide unreliable estimates of mortality. Under-recording of diabetes as a cause on death certificates has been widely reported, ranging from 15-60%. Using a population based register on peopl...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.49.6.570

    authors: Raymond NT,Langley JD,Goyder E,Botha JL,Burden AC,Hearnshaw JR

    更新日期:1995-12-01 00:00:00

  • Is the human sex ratio at birth a sentinel health indicator that is associated with HIV/AIDS and tuberculosis prevalences in the 21st century?

    abstract:BACKGROUND:A reduction in sex ratio at live birth has been proposed as a sentinel health indicator that can be used to monitor the health of populations. OBJECTIVE:To test the hypothesis that a lower sex ratio is associated with adverse national population health using the prevalences of HIV and tuberculosis as measur...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2011-200744

    authors: Shifotoka A,Fogarty AW

    更新日期:2013-04-01 00:00:00

  • Years of life lost due to encounters with law enforcement in the USA, 2015-2016.

    abstract:BACKGROUND:To inform discussions on rates, burden and priority-setting in relation to police violence, we quantified the number and rate of years of life lost (YLLs) due to police violence by race/ethnicity and age in the USA, 2015-2016. METHODS:We used data on the number of deaths due to police violence from 'The Cou...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2017-210059

    authors: Bui AL,Coates MM,Matthay EC

    更新日期:2018-08-01 00:00:00

  • Learning lessons from past mistakes: how can Health in All Policies fulfil its promises?

    abstract::The Ottawa Charter has exerted a great deal of influence on the public health debate and on health promotion practices over the last 25 years. The Charter shifted the main focus from individual risk behaviours to social determinants of health, and introduced innovative strategies such as participatory processes and em...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.2010.110437

    authors: Bacigalupe A,Esnaola S,Martín U,Zuazagoitia J

    更新日期:2010-06-01 00:00:00

  • Examining the effect of residential change on intimate partner violence risk.

    abstract:OBJECTIVES:To examine the relationship between residential change and a woman's subsequent risk of intimate partner violence (IPV), whether by a past or a new offender, a relationship that has not been prospectively examined to date. DESIGN:A dynamic cohort of women who recently changed residence (movers) was compared...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.2006.047084

    authors: Waltermaurer E,McNutt LA,Mattingly MJ

    更新日期:2006-11-01 00:00:00

  • Projections of cervical cancer mortality and incidence in New Zealand: the possible impact of screening.

    abstract:STUDY OBJECTIVE:The aim was to estimate the likely burden of cervical cancer in New Zealand over the next two decades, according to whether cervical screening services are made more effective. DESIGN:The study was based on national mortality and incidence data for the periods 1954-87 and 1954-86, respectively. An age-...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.46.4.373

    authors: Cox B,Skegg DC

    更新日期:1992-08-01 00:00:00

  • Leisure time exercise and personal circumstances in the working age population: longitudinal analysis of the British household panel survey.

    abstract:OBJECTIVES:Investigate the impact of social, economic, and family circumstances on participation in weekly leisure time exercise. DESIGN:Longitudinal regression analysis of the British household panel survey. PARTICIPANTS:9473 people (4521 men and 4952 women) giving 27,881 person years of responses across eight years...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.2005.041194

    authors: Popham F,Mitchell R

    更新日期:2006-03-01 00:00:00

  • Prevalence of overweight and obesity in East and West German children in the decade after reunification: population-based series of cross-sectional studies.

    abstract:OBJECTIVE:To analyse time trends in overweight and obesity from 1991 to 2000 in samples of German children and to test the hypothesis of a trend difference between the samples from East and West Germany during this time period. DESIGN:Repeated cross-sectional studies using data of 35,434 five to seven-year-old childre...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.2007.062117

    authors: Apfelbacher CJ,Cairns J,Bruckner T,Möhrenschlager M,Behrendt H,Ring J,Krämer U

    更新日期:2008-02-01 00:00:00

  • Incapacity for work in elective orthopaedic surgery: a study of occurrence and the probability of returning to work after treatment.

    abstract:STUDY OBJECTIVE:The extent to which patients undergoing elective surgery for orthopaedic disorders were incapacitated for work while they were on the waiting list and whether they were able to return to work after surgery were studied. DESIGN:This was a prospective cohort study of patients admitted to hospital for ele...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.47.5.388

    authors: Rossvoll I,Benum P,Bredland TR,Solstad K,Arntzen E,Jørgensen S

    更新日期:1993-10-01 00:00:00

  • Reported health, lifestyles, and use of health care of first generation immigrants in The Netherlands: do socioeconomic factors explain their adverse position?

    abstract:OBJECTIVE:Differences in health, lifestyles, and use of health care between groups of varying ethnic origin can have important implications for preventive and curative health care. This paper studies whether socioeconomic factors explain ethnic differences in these outcomes. DESIGN:Data on health status, lifestyles, a...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.52.5.298

    authors: Reijneveld SA

    更新日期:1998-05-01 00:00:00

  • Auditing and improving notification and chemoprophylaxis in bacterial meningitis.

    abstract:STUDY OBJECTIVE:The aim was to audit, against agreed standards, the control of bacterial meningitis, in particular completeness of notification and appropriateness of distribution of chemoprophylaxis to contacts; and to implement appropriate changes and monitor their impact. DESIGN:The first phase involved determinati...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.46.4.329

    authors: Harvey I,Kaul S,Peters TJ

    更新日期:1992-08-01 00:00:00

  • Impact of perceived control on all-cause and cardiovascular disease mortality in three urban populations of Central and Eastern Europe: the HAPIEE study.

    abstract:BACKGROUND:Inverse associations between perceived control and cardiovascular disease (CVD) have been reported in studies from Western Europe and the USA. To assess this relationship across different populations, we investigated the association between perceived control and all-cause and CVD mortality in three populatio...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2017-208992

    authors: Kozela M,Pająk A,Micek A,Besala A,Kubinova R,Malyutina S,Tamosiunas A,Pikhart H,Peasey A,Nikitin Y,Marmot M,Bobak M

    更新日期:2017-08-01 00:00:00

  • Cost and health consequences of reducing the population intake of salt.

    abstract:STUDY OBJECTIVE:The aim was to estimate health and economic consequences of interventions aimed at reducing the daily intake of salt (sodium chloride) by 6 g per person in the Norwegian population. Health promotion (information campaigns), development of new industry food recipes, declaration of salt content in food an...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.54.9.697

    authors: Selmer RM,Kristiansen IS,Haglerod A,Graff-Iversen S,Larsen HK,Meyer HE,Bonaa KH,Thelle DS

    更新日期:2000-09-01 00:00:00

  • Children at risk: measuring racial/ethnic disparities in potential exposure to air pollution at school and home.

    abstract:STUDY OBJECTIVE:This paper addresses the environmental justice implications of children's health by exploring racial/ethnic disparities in potential exposure to air pollution, based on both school and home locations of children and three different types of pollution sources, in Orange County, Florida, USA. METHODS:Usi...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.2006.054130

    authors: Chakraborty J,Zandbergen PA

    更新日期:2007-12-01 00:00:00

  • Antonovsky's sense of coherence scale and its relation with quality of life: a systematic review.

    abstract::The aim of this paper is to synthesise findings on the salutogenic concept, sense of coherence (SOC), and its correlation with quality of life (QoL). This study is descriptive and analytic, with a systematic integration of the contemporary knowledge base on the salutogenic research published in 1992-2003. This review ...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章,评审

    doi:10.1136/jech.2006.056028

    authors: Eriksson M,Lindström B

    更新日期:2007-11-01 00:00:00

  • Educational inequalities in blood pressure and cholesterol screening in nine European countries.

    abstract:BACKGROUND:To perform the first European overview of educational inequalities in the use of blood pressure and cholesterol screening. METHODS:Data were obtained on the use of screening services according to educational level from nationally representative cross-sectional surveys in Belgium, Czech Republic, Denmark, Es...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech-2011-200273

    authors: Rodin D,Stirbu I,Ekholm O,Dzurova D,Costa G,Mackenbach JP,Kunst AE

    更新日期:2012-11-01 00:00:00

  • Changes in tuberculosis notification rates in the white ethnic group in England and Wales between 1953 and 1983.

    abstract::Since the early 1960s notification rates for tuberculosis in England and Wales for the whole population have been influenced by high rates in certain ethnic groups. Using data based on country of birth from the British (Thoracic and) Tuberculosis Association surveys of 1965 and 1971, and based on ethnic origin from th...

    journal_title:Journal of epidemiology and community health

    pub_type: 杂志文章

    doi:10.1136/jech.42.4.370

    authors: Springett VH,Darbyshire JH,Nunn AJ,Sutherland I

    更新日期:1988-12-01 00:00:00