Abstract:
:The products of six unidentified reading frames of human mitochondrial DNA are precipitated from a mitochondrial lysate by antibodies against highly purified native beef heart NADH-ubiquinone oxidoreductase (complex I). These products are enriched greatly in a human submitochondrial fraction enriched in NADH-Q1 and NADH-K3Fe(CN)6 oxidoreductase activities. We conclude that the six reading frames encode components of the respiratory-chain NADH dehydrogenase.
journal_name
Naturejournal_title
Natureauthors
Chomyn A,Mariottini P,Cleeter MW,Ragan CI,Matsuno-Yagi A,Hatefi Y,Doolittle RF,Attardi Gdoi
10.1038/314592a0subject
Has Abstractpub_date
1985-04-18 00:00:00pages
592-7issue
6012eissn
0028-0836issn
1476-4687journal_volume
314pub_type
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