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Leishmania braziliensis: cell surface differences in promastigotes of pathogenic and nonpathogenic strains.

Abstract：

:A comparative study of cell surface characteristics of pathogenic and nonpathogenic promastigotes of Leishmania braziliensis, NR and LBY strains, respectively, was carried out by means of concanavalin A agglutination and labeling with concanavalin A-fluorescein isothiocyanate, concanavalin A-ferritin, and cationized ferritin. Cytochemical examination showed cell surface differences in lectin receptors and negative charge moieties in the two strains of L. braziliensis. The pathogenic NR strain agglutinated with low concentrations of concanavalin A and presented abundant lectin-binding and cationized ferritin-binding surface labeling. The nonpathogenic LBY strain neither agglutinated when incubated with concanavalin A, bound lectins, or cationized ferritin at the cell surface.

journal_name

Exp Parasitol

journal_title

Experimental parasitology

authors

Ayesta C,Argüello C,Hernández AG

doi

10.1016/0014-4894(85)90071-2

subject

Has Abstract

pub_date

1985-04-01 00:00:00

pages

185-91

issue

2

eissn

0014-4894

issn

1090-2449

pii

0014-4894(85)90071-2

journal_volume

59

pub_type

杂志文章

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