Abstract:
:Infection of cultured cells with herpes simplex virus (HSV) results in the transcriptional induction of a small number of cellular genes. Although the majority of such genes are dependent upon viral protein synthesis for their induction, a small minority are not. These genes are induced by events occurring prior to the onset of viral protein synthesis, in particular by binding of the virus to the cell surface and cellular entry of the virion. The significance of such cellular gene induction early in viral infection is discussed in terms of virus-cell interaction in general and the mechanism of transformation by HSV in particular.
journal_name
Nucleic Acids Resjournal_title
Nucleic acids researchauthors
Kemp LM,Preston CM,Preston VG,Latchman DSdoi
10.1093/nar/14.23.9261subject
Has Abstractpub_date
1986-12-09 00:00:00pages
9261-70issue
23eissn
0305-1048issn
1362-4962journal_volume
14pub_type
杂志文章abstract::The 'regions' method for multisequence alignment used in the previously reported program MALIGN has been generalized to include recursive refinement so that unaligned portions between two regions at the current level of resolution can be handled with increased resolution. Additionally, there is incorporated a limiting...
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journal_title:Nucleic acids research
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pub_type: 杂志文章
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更新日期:1994-10-11 00:00:00
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journal_title:Nucleic acids research
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journal_title:Nucleic acids research
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更新日期:2003-01-01 00:00:00
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journal_title:Nucleic acids research
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journal_title:Nucleic acids research
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