Distribution of LHRH in the rat and mouse brain with special reference to the tanycytes.

Abstract:

:The distribution of luteinizing hormone-releasing hormone (LHRH) was studied in the rat and mouse brain by means of light and electron microscopic immunohistochemistry using the peroxidase-antiperoxidase method. An immunoreactive product to LHRH antiserum was found near the blood vessels of the vascular organ of the lamina terminalis. In the arcuate nucleus-median eminence region, an immunoreactive material occurred bilaterally in the hypothalamic tissue around the tuberoinfundibular sulci. Electron microscopy revealed that immunoreactive fibers observed light microscopically contain numerous granules 100--130 nm in diameter. No immunoreactive product was located in the tanycytes of the median eminence, the perikarya of hypothalamic neurons, and the parenchyma of several circumventricular organs (subfornical organ, subcommissural organ, pineal organ, area postrema).

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

Nozaki M,Taketani Y,Minaguchi H,Kigawa T,Kobayashi H

doi

10.1007/BF00233914

subject

Has Abstract

pub_date

1979-03-19 00:00:00

pages

195-212

issue

2

eissn

0302-766X

issn

1432-0878

journal_volume

197

pub_type

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