Isolation and partial purification of Lantana (Lantana camara L.) toxins.

Abstract:

:A partially purified toxin fraction and lantadene A were obtained from Lantana camara L. leaves by batch extraction, column chromatography and fractional crystallization. Toxicity was tested in guinea pigs. The total number of chemical entities in the partially purified toxin preparation was 7, the 2 major ones being lantadene A and lantadene B. Lantadene A was nontoxic in itself. Likewise, another fraction containing lantadene A, lantadene B and 3 more components with higher polarity was found to be nontoxic. The toxic component(s) are different from lantadene A/B but appear to resemble them very closely.

journal_name

Toxicol Lett

journal_title

Toxicology letters

authors

Sharma OP,Dawra RK,Makkar HP

doi

10.1016/0378-4274(87)90153-6

subject

Has Abstract

pub_date

1987-07-01 00:00:00

pages

165-72

issue

2

eissn

0378-4274

issn

1879-3169

pii

0378-4274(87)90153-6

journal_volume

37

pub_type

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