[Problems in the evaluation of contraceptives (author's transl)].

Abstract:

:For the evaluation of the effectiveness of contraceptives the Life Table method is at present the best method. It is a disadvantage that the original method of Tietze & Potter was restricted to the evaluation of intra-uterine contraception devices. A Belgian team is now in the process of developing a modified life table method for the evaluation of the effectiveness and the side effects of oral contraceptives. The reference to the Pearl-index for the effectiveness of contraceptives is unclear and in the way in which it is at present used scientifically untenable. :The Pearl Index and the Life-Table Method, used to evaluate contraceptive methods, are discussed. The Pearl Index is based on "patient error", a concept no longer valid. Also, there is no figure to serve as an absolute basis for the Index, as it is based on the possible number of pregnancies in 1200 unprotected cycles. This figure ranges from 40 to 90 in the literature. The Life-Table Method correlates the occurrence of pregnancies and side effects in consecutive months of contraceptive use, and considers such events separately from discontinuations. Thus, it can be used to relate the occurrence of side effects to length of contraceptive use. It must be used, however, on material from at least 50 patients to give significant results. The Life-Table Method also uses socioeconomic data in its analysis and eliminates patient error. It is preferable to the Pearl Index but has so far been developed only for determining the effectiveness of IUDs.

authors

Beckmann M,Dame WR,Beller FK

subject

Has Abstract

pub_date

1978-08-01 00:00:00

pages

640-2

issue

8

eissn

0016-5751

issn

1438-8804

journal_volume

38

pub_type

临床试验,杂志文章
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  • [Significance of 17-hydroxyprogesterone for the diagnosis of ovulation].

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