Species specificity and lack of production of STb enterotoxin by Escherichia coli strains isolated from humans with diarrheal illness.

abstract：:An inactivated oral enterotoxigenic Escherichia coli (ETEC) vaccine against ETEC diarrhea was given to 25 adult Swedish volunteers. The vaccine consisted of formalin-killed E. coli bacteria expressing the most common colonization factor antigens (CFAs), i.e., CFA/I, -II, and -IV, and recombinantly produced cholera B s...

journal_title：Infection and immunity

authors： Ahrén C,Jertborn M,Svennerholm AM

更新日期：1998-07-01 00:00:00

abstract：:Borrelia burgdorferi, the Lyme disease-causing spirochete, can persistently infect its vertebrate hosts for years. B. burgdorferi is often found associated with host connective tissue, where it interacts with components of the extracellular matrix, including fibronectin. Some years ago, a borrelial surface protein, na...

journal_title：Infection and immunity

authors： Brissette CA,Bykowski T,Cooley AE,Bowman A,Stevenson B

更新日期：2009-07-01 00:00:00

abstract：:Surface proteins in gram-positive bacteria are frequently required for virulence, and many are attached to the cell wall by sortase enzymes. Bacteria frequently encode more than one sortase enzyme and an even larger number of potential sortase substrates that possess an LPXTG-type cell wall sorting signal. In order to...

journal_title：Infection and immunity

authors： Comfort D,Clubb RT

更新日期：2004-05-01 00:00:00

abstract：:Mycoplasma penetrans adhered to cultured human cells, forming clusters that localized to specific areas of the host cell surface. Adherence and cluster formation were inhibited by anti-M. penetrans antibodies, suggesting the involvement of specific adhesin-receptor interactions. Ultrastructural studies showed that aft...

journal_title：Infection and immunity

authors： Girón JA,Lange M,Baseman JB

更新日期：1996-01-01 00:00:00

abstract：:Mononuclear phagocytes provide the major habitat of intracellular bacteria, including Mycobacterium tuberculosis and Mycobacterium bovis. The capacity of B-cell stimulatory factor 2 (interleukin-6 [IL-6]) to activate tuberculostatic functions was investigated by using murine bone marrow-derived macrophages (BMM phi). ...

journal_title：Infection and immunity

authors： Flesch IE,Kaufmann SH

更新日期：1990-01-01 00:00:00

abstract：:Enterococcus faecalis is a highly stress resistant opportunistic pathogen. The intrinsic ruggedness of this bacterium is supposed to be the basis of its capacity to colonize the hostile environments of hospitals and to cause several kinds of infections. We show in this work that general resistance to very different en...

journal_title：Infection and immunity

authors： Rana NF,Sauvageot N,Laplace JM,Bao Y,Nes I,Rincé A,Posteraro B,Sanguinetti M,Hartke A

更新日期：2013-08-01 00:00:00

abstract：:Intracellular multiplication of virulent Legionella pneumophila serogroup 1 was inhibited by human monocyte-derived macrophages activated by a glycoprotein extract of Klebsiella pneumoniae, RU 41.740. Macrophage cultures were infected with L. pneumophila in the presence of immune antibodies on day 7 of culture. Extrac...

journal_title：Infection and immunity

authors： Rajagopalan P,Dournon E,Vildé JL,Pocidalo JJ

更新日期：1987-09-01 00:00:00

abstract：:In this study we have characterized the association of a polysaccharide-deficient, lipid-rich lipopolysaccharide (LPS) with rabbit erythrocytes (RaRBC). With polymyxin B sulfate-mediated hemolysis as a probe, we have shown that Salmonella minnesota R595 LPS interacts with RaRBC in two distinguishable steps. The first ...

journal_title：Infection and immunity

authors： Carr C Jr,Morrison DC

更新日期：1984-02-01 00:00:00

abstract：:Group A streptococcal cell walls inhibited phagocytosis of polystyrene latex particles by rat peritoneal macrophages in vitro. This inhibition was not accompanied by a measurable loss of cell viability. Group D streptococcal cell walls were relatively ineffective in altering phagocytosis. The effectiveness of group A ...

journal_title：Infection and immunity

authors： Smialowicz RJ,Schwab JH

更新日期：1978-04-01 00:00:00

abstract：:Apical membrane antigen 1 (AMA1) is expressed on the surfaces of Plasmodium falciparum merozoites and is thought to play an important role in the invasion of erythrocytes by malaria parasites. To select for peptides that mimic conformational B-cell epitopes on AMA1, we screened a phage display library of >10(8) indivi...

journal_title：Infection and immunity

authors： Casey JL,Coley AM,Anders RF,Murphy VJ,Humberstone KS,Thomas AW,Foley M

更新日期：2004-02-01 00:00:00

abstract：:Serum from rabbits immunized with either heat-killed or live nonencapsulated Staphylococcus aureus failed further to enhance phagocytosis and intracellular killing of the homologous organism by either normal rabbit polymorphonuclear leukocytes or monocytes, when compared with normal rabbit serum. These immune sera did...

journal_title：Infection and immunity

authors： Shayegani M

更新日期：1970-12-01 00:00:00

abstract：:Antibodies against mumps virus have been studied by using immunoglobulin class-specific indicators labeled with (125)I in the radioimmunoassay (RIA) procedure. The immunoglobulins in paired acute and convalescent sera were allowed to react with mumps virus in a solid-phase RIA system. Class-specific immunoglobulin ind...

journal_title：Infection and immunity

authors： Daugharty H,Warfield DT,Hemingway WD,Casey HL

更新日期：1973-03-01 00:00:00

abstract：:The lipooligosaccharide (LOS) present in the outer membrane of Haemophilus ducreyi is likely a virulence factor for this sexually transmitted pathogen. An open reading frame in H. ducreyi 35000 was found to encode a predicted protein that had 87% identity with the protein product of the gmhA (isn) gene of Haemophilus ...

journal_title：Infection and immunity

authors： Bauer BA,Stevens MK,Hansen EJ

更新日期：1998-09-01 00:00:00

abstract：:Hybridomas secreting monoclonal antibodies against an apparent strain-specific cell surface antigen of Neisseria gonorrhoeae were produced. Spleen cells from BALB/c mice immunized with whole gonococci were fused with mouse myeloma cell line Sp2/0, and hybrid cells were selected in culture. One hybridoma that secreted ...

journal_title：Infection and immunity

authors： Nachamkin I,Cannon JG,Mittler RS

更新日期：1981-05-01 00:00:00

abstract：:Nontypeable Haemophilus influenzae (NTHi) causes repeated respiratory infections in patients with chronic lung diseases. These infections are characterized by a brisk inflammatory response which results in the accumulation of polymorphonucleated cells in the lungs and is dependent on the expression and secretion of pr...

journal_title：Infection and immunity

authors： Clemans DL,Bauer RJ,Hanson JA,Hobbs MV,St Geme JW 3rd,Marrs CF,Gilsdorf JR

更新日期：2000-08-01 00:00:00

abstract：:To test the importance of lipopolysaccharide (LPS) and adhesin as major antigens in vaccination against rabbit enteropathogenic Escherichia coli (EPEC)-like E. coli O103 infection, we used two nonpathogenic wild-type strains to immunize rabbits at weaning. One of these strains (C127) harbors the O103 LPS but does not ...

journal_title：Infection and immunity

authors： Milon A,Esslinger J,Camguilhem R

更新日期：1992-07-01 00:00:00

abstract：:Genomic DNA fingerprint analysis was performed on 39 Staphylococcus aureus and 28 Enterococcus faecalis endophthalmitis isolates collected from multiple clinical centers. Among 21 S. aureus genomic DNA fingerprint patterns identified, five clonotypes were recovered from multiple unrelated patients and accounted for 58...

journal_title：Infection and immunity

authors： Booth MC,Hatter KL,Miller D,Davis J,Kowalski R,Parke DW,Chodosh J,Jett BD,Callegan MC,Penland R,Gilmore MS

更新日期：1998-01-01 00:00:00

abstract：:The attachment of radioisotope-labeled Mycoplasma pneumoniae to hamster tracheal rings in organ culture was examined by radioautography and liquid scintillation counting. Radioautographs of individual rings exposed for 8 h to (3H) thymidine-labeled virulent M. pneumoniae revealed a dense extracellular collection of em...

journal_title：Infection and immunity

authors： Powell DA,Hu PC,Wilson M,Collier AM,Baseman JB

更新日期：1976-03-01 00:00:00

abstract：:A monoclonal antibody (MAb) was raised against Shiga toxin 2 (Stx2) of Escherichia coli O157:H7. MAb VTm1.1 belonged to the immunoglobulin G1 subclass and had a kappa light chain, and it could neutralize the cytotoxic activity of Stx2 and variants derived from patient strains but not that of variants derived from anim...

journal_title：Infection and immunity

authors： Nakao H,Kiyokawa N,Fujimoto J,Yamasaki S,Takeda T

更新日期：1999-11-01 00:00:00

abstract：:Exposure of hamster tracheal rings in organ culture to virulent Mycoplasma pneumoniae organisms leads to alterations in macromolecular biosynthesis and metabolic activity of the respiratory epithelial cells. Avirulent organisms derived from the same parent strain do not produce these effects. During the course of infe...

journal_title：Infection and immunity

authors： Hu PC,Collier AM,Baseman JB

更新日期：1975-04-01 00:00:00

abstract：:Reinfection of immune mice with Leishmania major elicits a secondary gamma interferon (IFN-gamma) response to which specific CD8+ T cells are essential. We have shown previously that specific CD8+ T cells from reinfected immune mice release substantially higher levels of IFN-gamma, a cytokine essential for the efficie...

journal_title：Infection and immunity

authors： Müller I,Kropf P,Louis JA,Milon G

更新日期：1994-06-01 00:00:00

abstract：:Two inbred mouse strains, derived from feral founders, are susceptible to experimental leishmaniasis due to Leishmania major and support a disease of a severity intermediate between those observed in strains C57BL/6 and BALB/c. Mice of the MAI strain develop a severe, nonhealing, but nonfatal disease with no resistanc...

journal_title：Infection and immunity

authors： Babay BE,Louzir H,Kebaïer C,Boubaker S,Dellagi K,Cazenave PA

更新日期：2004-08-01 00:00:00

abstract：:The adhesion of K21a, K26, K36, and K50 capsulated Klebsiella strains to ileocecal (HCT-8) and bladder (T24) epithelial cell lines was significantly lower than that of their corresponding spontaneous noncapsulated variants K21a/3, K26/1, K36/3, and K50/3, respectively. Internalization of the bacteria by both epithelia...

journal_title：Infection and immunity

authors： Sahly H,Podschun R,Oelschlaeger TA,Greiwe M,Parolis H,Hasty D,Kekow J,Ullmann U,Ofek I,Sela S

更新日期：2000-12-01 00:00:00

abstract：:The adherence protein (P1 protein) of Mycoplasma pneumoniae was purified by electroelution and cleaved with cyanogen bromide. The resulting peptides were separated by two-dimensional electrophoresis. Spots reacting in Western immunoblots with two attachment-inhibiting monoclonal antibodies were isolated, and the amino...

journal_title：Infection and immunity

authors： Jacobs E,Gerstenecker B,Mader B,Huang CH,Hu PC,Halter R,Bredt W

更新日期：1989-03-01 00:00:00

abstract：:Arg-gingipains are extracellular cysteine proteases produced by the gram-negative periodontal pathogen Porphyromonas gingivalis and are encoded by rgpA and rgpB. Three Arg-gingipains, heterodimeric high-molecular-mass Arg-gingipain HRgpA comprising the alpha-catalytic chain and the beta-adhesin chain, the monomeric so...

journal_title：Infection and immunity

authors： Rangarajan M,Hashim A,Aduse-Opoku J,Paramonov N,Hounsell EF,Curtis MA

更新日期：2005-08-01 00:00:00

abstract：:Deoxyribonucleic acid (DNA) base composition, as measured by guanine plus cytosine (G + C) content, was determined in 17 strains of Sporothrix schenckii and Ceratocystis species. The average G + C content for S. schenckii was 54.7 +/- 0.2 mol%. No strain of Ceratocystis, with the exception of C. minor, gave values for...

journal_title：Infection and immunity

authors： Mendonça-Hagler LC,Travassos LR,Lloyd KO,Phaff HJ

更新日期：1974-05-01 00:00:00

abstract：:gammaG-globulin from nonimmunized rabbits and from rabbits immunized with various bacteria reacted in the immunofluorescence technique with protein A-containing Staphylococcus aureus. Pepsin digestion of most immunoglobulin preparations eliminated the reaction, thus showing that the Fc fragment is involved and that th...

journal_title：Infection and immunity

authors： Forsgren A,Forsum U

更新日期：1970-10-01 00:00:00

abstract：:Helicobacter pylori is an important human pathogen that causes gastritis and is strongly associated with gastric ulcers, gastric adenocarcinomas, and mucosa-associated lymphoid tissue lymphomas. In response to H. pylori, interleukin-8 (IL-8) is secreted from host cells to attract components of the innate and adaptive ...

journal_title：Infection and immunity

authors： Torok AM,Bouton AH,Goldberg JB

更新日期：2005-03-01 00:00:00

abstract：:The theoretic basis for developing conjugate vaccines, to induce immunoglobulin G (IgG) lipopolysaccharide (LPS) antibodies for the prevention of shigellosis, has been described (J. B. Robbins, C.-Y. Chu, and R. Schneerson, Clin. Infect. Dis. 15:346-361, 1992). The O-specific polysaccharides (O-SPs) of Shigella dysent...

journal_title：Infection and immunity

authors： Taylor DN,Trofa AC,Sadoff J,Chu C,Bryla D,Shiloach J,Cohen D,Ashkenazi S,Lerman Y,Egan W

更新日期：1993-09-01 00:00:00

abstract：:Alveolar bone resorption can be induced in specific-pathogen-free mice by oral infection with Porphyromonas gingivalis (P. J. Baker, R. T. Evans, and D. C. Roopenian, Arch. Oral Biol. 39:1035-1040, 1994). Here we used a mouse strain, C57BL/6J, which is relatively resistant to P. gingivalis-induced bone loss to examine...

journal_title：Infection and immunity

authors： Baker PJ,DuFour L,Dixon M,Roopenian DC

更新日期：2000-06-01 00:00:00