Abstract:
:Eighty-two cases of primary neoplasms of the spine, diagnosed and treated at the University of Iowa, were reviewed in an attempt to identify features of diagnostic and prognostic importance, and to evaluate the effectiveness of surgical treatment with respect to survival. Thirty-one benign and 51 malignant tumors were identified. The mean follow-up in benign lesions was 9.7 years and 3.8 years in malignant lesions. Plain roentgenograms demonstrated the spinal lesion in 81 of 82 cases (99%). All spinal segments were involved, the cervical spine least frequently. Malignancy proved to be associated with an older age at diagnosis, a higher incidence of neurologic deficit, and a higher incidence of occurrence in the vertebral body. Five-year survival for patients with benign tumors was 86%, with no significant relationship between type of surgery and survival. Five-year survival in malignant lesions did correlate with the extent of initial surgery and with the tumor type. Five-year survival in patients undergoing curettage for malignancy was nil, in those undergoing incomplete resection, 18.7%, and in patients having complete excision, 75%. Plain anteroposterior and lateral roentgenograms should be obtained as a screening study in patients with persistent or atypical back pain or neurologic signs. CT scanning, myelography, and magnetic resonance imaging studies may be utilized to establish the physical margins of the lesion and to evaluate cord impingement. Surgical extirpation should be attempted whenever possible in malignant and benign aggressive lesions. In this series, the prolonged survival seen with complete excision justifies an aggressive surgical approach to the treatment of these tumors.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Spine (Phila Pa 1976)journal_title
Spineauthors
Weinstein JN,McLain RFdoi
10.1097/00007632-198711000-00004subject
Has Abstractpub_date
1987-11-01 00:00:00pages
843-51issue
9eissn
0362-2436issn
1528-1159journal_volume
12pub_type
杂志文章相关文献
SPINE文献大全abstract::Thirty patients with myelographic shortening of a single nerve root sheath without indentation of the dural sac were studied by CT. Lateral disc herniation was diagnosed by CT in 18 patients. The myelograms of these patients were considered suspicious of disc herniation in three patients, uncertain in seven, and misin...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198606000-00020
更新日期:1986-06-01 00:00:00
abstract:STUDY DESIGN:We performed a retrospective study of spinal roentgenograms of a large cohort of patients suffering from osteogenesis imperfecta. OBJECTIVE:To determine the prevalence of vertebral pars defects (spondylolysis) in patients with osteogenesis imperfecta. SUMMARY OF BACKGROUND DATA:Patients suffering from os...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181a39646
更新日期:2009-06-01 00:00:00
abstract:STUDY DESIGN:A prospective assessment, performed using the Health Status Questionnaire, of the outcomes for 28 patients with cervical radiculopathy treated with one- or two-level anterior cervical discectomy and fusion. OBJECTIVE:To assess patient outcome using the Health Status Questionnaire after one- or two-level a...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-200004010-00007
更新日期:2000-04-01 00:00:00
abstract:STUDY DESIGN:In this study, data are presented that provide the surgeon with additional information about the internal structure of the thoracic pedicle, which is especially useful for pedicle screw fixation in the thoracic spine. OBJECTIVES:To quantify the internal structure of the pedicle in the thoracic spine. SUM...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199602010-00002
更新日期:1996-02-01 00:00:00
abstract::Two examples of a marked defect of the corner of the vertebral body adjacent to an intervertebral disk herniation are presented. The prevalence of this finding was assessed in 43 randomly selected patients with disk herniation (at 46 levels). None of these patients had such marked vertebral defects (moderate changes a...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199301000-00016
更新日期:1993-01-01 00:00:00
abstract:STUDY DESIGN:Recall of the informed consent process in patients undergoing adult spinal deformity surgery and their family members was investigated prospectively. OBJECTIVE:To quantify the percentage recall of the most common complications discussed during the informed consent process in adult spinal deformity surgery...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000000964
更新日期:2015-07-15 00:00:00
abstract:STUDY DESIGN:A cell-based assay was developed to identify asymptomatic children at risk of developing idiopathic scoliosis (IS) and to stratify IS patients at an earlier stage in order to better predict their clinical outcome. Clinical validation of this assay was performed by testing IS patients at different stages, h...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181cf39ff
更新日期:2010-06-01 00:00:00
abstract:STUDY DESIGN:Retrospective analysis. OBJECTIVE:To compare radiographical analysis and clinical outcomes of spinal osteotomy techniques, including Smith-Petersen osteotomy (SPO), pedicle subtraction osteotomy (PSO), and vertebral column resection (VCR), and analyze the relationship between preoperative evaluation and p...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000000728
更新日期:2015-03-01 00:00:00
abstract:STUDY DESIGN:A descriptive cadaveric study. OBJECTIVE:To investigate the anatomy and innervation of the uncovertebral joint to determine if it is synovial in nature and capable of generating pain. SUMMARY OF BACKGROUND DATA:There is controversy with regard to the anatomic and histological makeup of the uncovertebral ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e31819b2b5d
更新日期:2009-05-20 00:00:00
abstract::In a random, controlled laboratory study, pedicle screws placed in human cadaveric vertebrae were axially loaded to failure. Three repair methods were tested. Use of low pressure polymethylmethacrylate yielded 149% of the original pullout strength, milled bone yielded 70% of the initial pullout strength, and matchstic...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199402000-00017
更新日期:1994-02-01 00:00:00
abstract:STUDY DESIGN:This is a retrospective analysis of 30 pediatric deformity surgeries. OBJECTIVE:The purpose of this study was to evaluate the accuracy of neuromonitoring in comparison to postoperative computed tomography scans for pedicle screw position. SUMMARY OF BACKGROUND DATA:Triggered electromyography potentials i...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181b3f467
更新日期:2010-01-15 00:00:00
abstract::Twenty-one with symptomatic cervical spondylosis or nonspecific neck pain were given an amnesic dose of diazepam before manipulation of the cervical spine. Eighteen patients served as controls and also received diazepam but no manipulation. Results were obtained in a randomized, double-blind fashion. Statements of out...
journal_title:Spine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007632-198211000-00003
更新日期:1982-11-01 00:00:00
abstract:STUDY DESIGN:A prospective study in two groups of patients selected randomly. OBJECTIVES:To determine whether keeping the outer and inner cortices of the ilium intact, while obtaining bone graft, would result in reduced postoperative bleeding and less postoperative pain. SUMMARY OF BACKGROUND DATA:Donor site complica...
journal_title:Spine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007632-200007010-00018
更新日期:2000-07-01 00:00:00
abstract:STUDY DESIGN:Case report. OBJECTIVE:To report a case of false-negative intraoperative motor-evoked potentials (MEP) that developed paraplegia after surgery. SUMMARY OF BACKGROUND DATA:Although several false-negative results have been reported with somatosensory-evoked potentials, there is no report noted with MEP. Th...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/BRS.0b013e3181b40d4f
更新日期:2009-11-15 00:00:00
abstract:STUDY DESIGN:Case report. OBJECTIVES:To report 2 unusual cases of Pseudomonas aeruginosa epidural abscesses and cervical osteomyelitis after routine dental extractions and to review relevant literature. SUMMARY OF BACKGROUND DATA:Pseudomonas aeruginosa is a rare cause of cervical osteomyelitis in patients after denta...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/BRS.0b013e31816c9120
更新日期:2008-04-20 00:00:00
abstract:STUDY DESIGN:Retrospective study. OBJECTIVE:Evaluate the relationship among the neurologic status, the Thoracolumbar Injury Classification System (TLICS) score, and the Magerl/AO classification system. SUMMARY OF THE BACKGROUND DATA:A wide range of classification schemes for thoracic and lumbar spine trauma have been...
journal_title:Spine
pub_type: 杂志文章,多中心研究
doi:10.1097/BRS.0b013e3181c95047
更新日期:2011-01-01 00:00:00
abstract:STUDY DESIGN:Prospective cross-sectional measurement study. OBJECTIVE:To determine the ability of the Scoliosis Research Society (SRS)-22 questionnaire to discriminate among management and scoliosis severity subgroups and to correlate with internal and external measures of curve severity. SUMMARY OF BACKGROUND DATA:I...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181af28bf
更新日期:2009-10-15 00:00:00
abstract:STUDY DESIGN:A pragmatic cluster randomized controlled trial in primary care. OBJECTIVE:The aim of this study was to estimate the clinical effectiveness and cost-effectiveness of a cognitive-based education program on patients with subacute or chronic low back pain (LBP) in primary care, compared to usual treatment, p...
journal_title:Spine
pub_type: 杂志文章,随机对照试验
doi:10.1097/BRS.0000000000001268
更新日期:2016-03-01 00:00:00
abstract:STUDY DESIGN:This retrospective study analyzes the timing of spinal metastases and the survivability of patients with cancer after the detection of spinal metastases. OBJECTIVE:To evaluate the timing of spinal metastases in primary lesions and the survivability of patients with metastatic spinal tumors. SUMMARY OF BA...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199609150-00017
更新日期:1996-09-15 00:00:00
abstract:STUDY DESIGN:A systematic review of the literature including statistical meta-analysis. OBJECTIVES:To evaluate published methods of the test of Lasègue or straight leg raising test and the cross straight leg raising test by using a recently developed criteria list and to summarize and explore reasons for variation in ...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/00007632-200005010-00016
更新日期:2000-05-01 00:00:00
abstract:STUDY DESIGN:Two thousand consecutive idiopathic scoliosis records and radiographs were reviewed for coronal pattern typing and categorization, based on Scoliosis Research Society definitions of the apical vertebra. Apical frequency was determined for each of the patterns identified, and represents a database from a la...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199806150-00016
更新日期:1998-06-15 00:00:00
abstract:STUDY DESIGN:Analysis of the patients with spinal missile injury (SMI). OBJECTIVE:Choosing the optimum treatment for SMI with respect to bullet trajectory, evaluation of surgical indications, and timing of surgical intervention. SUMMARY OF BACKGROUND DATA:A few guidelines were reported for the management of SMI. But ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e31818579a7
更新日期:2008-09-15 00:00:00
abstract:STUDY DESIGN:An experimental study of healthy subjects' trunk muscle responses to force perturbations at differing angles and steady state efforts. OBJECTIVES:To determine whether increased preactivation of muscles was associated with decreased likelihood of muscular activation in response to a transient force perturb...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-200008010-00015
更新日期:2000-08-01 00:00:00
abstract:STUDY DESIGN:A cross-sectional study. OBJECTIVE:To identify facet tropism as one of the possible risk factors leading to vertebral rotatory subluxation (VRS). SUMMARY OF BACKGROUND DATA:VRS has been considered as one of the prognostic factors for degenerative scoliosis. Although several risk factors of VRS, including...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000000494
更新日期:2014-12-15 00:00:00
abstract:STUDY DESIGN:Retrospective study. OBJECTIVE:To determine whether postoperative pseudarthrosis can be predicted from specific preoperative radiograph measurements. SUMMARY OF BACKGROUND DATA:Various factors reportedly influence the occurrence of pseudarthrosis after anterior cervical discectomy and fusion (ACDF). Howe...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000002219
更新日期:2017-12-01 00:00:00
abstract:STUDY DESIGN:Systematic Review. OBJECTIVES:To assess the effects of massage therapy for nonspecific low back pain. SUMMARY OF BACKGROUND DATA:Low back pain is one of the most common and costly musculoskeletal problems in modern society. Proponents of massage therapy claim it can minimize pain and disability, and spee...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181ad7bd6
更新日期:2009-07-15 00:00:00
abstract:STUDY DESIGN:retrospective review. OBJECTIVE:to determine if Anterior/Posterior Combined approach spine surgery is associated with an increased risk of pulmonary embolism (PE) compared to Posterior Only approach surgery. SUMMARY OF BACKGROUND DATA:combined anterior/posterior approach spine surgery is associated with ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181cb4717
更新日期:2011-01-15 00:00:00
abstract:STUDY DESIGN:A case report of Trichosporon asahii spondylodiscitis. OBJECTIVE:To report the first case of T. asahii spondylodiscitis that developed in a healthy woman at the site of an open lumbar discectomy. SUMMARY OF BACKGROUND DATA:Trichosporon is a genus of basidiomycetous yeasts that is common in nature and a m...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181642a7c
更新日期:2008-02-15 00:00:00
abstract:STUDY DESIGN:Clinical, neuroradiologic, and neurophysiologic description of 21 patients with compressive cervical spondylotic myelopathy (CCSM). OBJECTIVE:To describe the utility of cutaneous silent periods (CSPs) for functional evaluation of mild CCSM. SUMMARY OF BACKGROUND DATA:Electroneurography, electromyography,...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e31818f8be3
更新日期:2009-01-01 00:00:00
abstract:STUDY DESIGN:Prospective randomized comparison of anterior lumbar interbody fusion (ALIF) plus transpedicular instrumentation plus posterolateral fusion (PLF) (360 degrees fusion) to ALIF plus transpedicular instrumentation without PLF (270 degrees fusion). OBJECTIVES:To compare the clinical outcomes, costs, and utili...
journal_title:Spine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007632-200105150-00019
更新日期:2001-05-15 00:00:00