The effect of L-asparaginase on lipid metabolism during induction chemotherapy of childhood lymphoblastic leukaemia.

abstract：:Respiratory and arousal responses to mild hypoxia (15% oxygen in nitrogen) were recorded in 18 healthy infants and 33 infants who had sustained severe sleep related apnoeic events (ALTE). Respiratory movements and transcutaneous gas pressures (tcPO2 and tcPCO2) were continuously monitored during the 10 min test. The c...

journal_title：European journal of pediatrics

authors： Milerad J,Hertzberg T,Wennergren G,Lagercrantz H

更新日期：1989-04-01 00:00:00

abstract：UNLABELLED:To assess the efficacy of a serotonin re-uptake inhibitor, sertraline hydrochloride, in preventing recurrent neurocardiogenic syncope, we studied 15 patients (10 female; mean age 12.9 +/- 2 years) with positive head-upright tilt test and resistant to standard pharmacotherapy, atenolol or disopyramide. The pa...

journal_title：European journal of pediatrics

authors： Lenk M,Alehan D,Ozme S,Celiker A,Ozer S

更新日期：1997-10-01 00:00:00

abstract：UNLABELLED:We describe the case of a 6-year-old girl brought to the emergency department for the sudden onset of anticholinergic syndrome after the ingestion of a few home-made partially debittered lupine beans. She complained of blurry vision, headache, photophobia and nausea. No specific treatment was needed, and the...

journal_title：European journal of pediatrics

authors： Daverio M,Cavicchiolo ME,Grotto P,Lonati D,Cananzi M,Da Dalt L

更新日期：2014-12-01 00:00:00

abstract：UNLABELLED:Click-evoked oto-acoustic emissions (CEOAE) are acoustic responses produced by the inner ear, reflecting functional auditory integrity. We studied both the success rate of the CEOAE method and the CEOAE presence in preterm infants during their stay at the Neonatal Intensive Care Unit (NICU), by analysis of t...

journal_title：European journal of pediatrics

authors： Brienesse P,Maertzdorf WJ,Anteunis LJ,Manni JJ,Blanco CE

更新日期：1998-12-01 00:00:00

abstract：:In our clinic the decision on whether to continue with dietary treatment of phenylketonuria or not is left to each adolescent and adult patient after the advantages and disadvantages, as discussed in this paper, of continuing diet have been presented to them. As a result 61 of 132 patients have stopped diet or decline...

journal_title：European journal of pediatrics

authors： Brenton DP,Tarn AC,Cabrera-Abreu JC,Lilburn M

更新日期：1996-07-01 00:00:00

abstract：:Following a description of the genetic aspects of the human histocompatibility antigens system HLA and its principle typing methods, this paper reviews the relationship between HLA antigens, transplantation immunology and certain diseases. In particular, the role of the lymphocyte-defined antigens of the HLA-D system ...

journal_title：European journal of pediatrics

authors： Passarge E,Valentine-Thon E

更新日期：1980-03-01 00:00:00

abstract：:This study was conducted to assess the clinical spectrum, management, and outcome of SARS-CoV-2-related multisystem inflammatory syndrome in children (MIS-C). We reviewed medical records of children with MIS-C diagnosis seen at the Children's Hospital of Michigan in Detroit between April and June 2020. Thirty-three ch...

journal_title：European journal of pediatrics

authors： Abdel-Haq N,Asmar BI,Deza Leon MP,McGrath EJ,Arora HS,Cashen K,Tilford B,Charaf Eddine A,Sethuraman U,Ang JY

更新日期：2021-01-16 00:00:00

abstract：:The molecular polymorphism and quantitative levels of serum vitamin D-binding protein (DBP) were ascertained in a group of preterm, full-term and hypocalcaemic full-term newborn infants. The serum concentration of DBP is not influenced by phenotype and increases with fetal age from the 32nd-33rd week of gestation unti...

journal_title：European journal of pediatrics

authors： Auconi P,Biagini R,Colarizi P,Luciano R,Pascali VL,Rastelli D,Tortorolo G

更新日期：1985-09-01 00:00:00

abstract：:To increase our knowledge of the clonal relationship of leukaemia relapse, the genotypes and phenotypes of ten children with acute lymphoblastic leukaemia (ALL) were examined at initial diagnosis and relapse. Seven patients were phenotyped as common ALL, two as mixed, and one as T-cell ALL (T-ALL). Comparative analyse...

journal_title：European journal of pediatrics

authors： Raghavachar A,Ludwig WD,Bartram CR

更新日期：1988-06-01 00:00:00

abstract：:Histochemical and immunohistochemical studies performed in only a few cases of sinus histiocytosis with massive lymphoadenopathy (SHML) indicated that SHML cells belong to the macrophage--histiocyte system, though their exact origin is still uncertain. We analyzed the morphological, antigenic and enzymatic characteris...

journal_title：European journal of pediatrics

authors： Paulli M,Locatelli F,Kindl S,Boveri E,Facchetti F,Porta F,Rosso R,Nespoli L,Magrini U

更新日期：1992-09-01 00:00:00

abstract：:Congenital diaphragmatic eventration (CDE) and congenital diaphragmatic hernia (CDH) with or without hernia sac are three different types of congenital diaphragmatic malformations, which this study evaluates. All surgically treated patients with CDE or Bochdalek type CDH between 2000 and 2016 were included in this ret...

journal_title：European journal of pediatrics

authors： Heiwegen K,van Heijst AF,Daniels-Scharbatke H,van Peperstraten MC,de Blaauw I,Botden SM

更新日期：2020-06-01 00:00:00

abstract：:Mid-aortic syndrome is characterized by narrowing of the abdominal aorta, usually with the involvement of renal arteries and other visceral branches. The combination of the presence of an abdominal bruit, diminished or absent pulsations of the lower extremities, and a blood pressure discrepancy between upper and lower...

journal_title：European journal of pediatrics

authors： ten Dam K,van der Palen RL,Tanke RB,Schreuder MF,de Jong H

更新日期：2013-03-01 00:00:00

abstract：:This was a retrospective study documenting all pacemaker implantations (PMIs) secondary to postoperative atrioventricular block. A total of 26 patients were included between 2011 and 2020. The incidence rate was 1.8%, with a median follow-up time of 4.5 years. At the time of the initial PMI, the median weight was 5 kg...

journal_title：European journal of pediatrics

authors： Ebrahim MA,Ashkanani HK,Alramzi RS,Malhas ZI,Al-Bahrani M,Sadek AA,Elsayed MA,Lyubomudrov VG

更新日期：2020-12-01 00:00:00

abstract：:The triad of adrenocortical insufficiency with alacrima and achalasia is an unusual disease entity in paediatrics. The association of autonomic and peripheral neuropathies has more commonly been reported in older individuals. We describe four children (two siblings) with this disorder, aged between 3 and 6 years at di...

journal_title：European journal of pediatrics

authors： Gazarian M,Cowell CT,Bonney M,Grigor WG

更新日期：1995-01-01 00:00:00

abstract：UNLABELLED:Periventricular leucomalacia is a condition that causes lifelong disability and considerable economic burden. It occurs in premature infants of less than 32 weeks gestation due to their unique anatomical features. The white matter of these infants is poorly vascularised and contains oligodendrocyte progenito...

journal_title：European journal of pediatrics

authors： Blumenthal I

更新日期：2004-08-01 00:00:00

abstract：:The phenylalanine hydroxylase (PAH) deficiency trait is heterogeneous with a continuum of metabolic phenotypes ranging from classical phenylketonuria (PKU) to mild hyperphenylalaninaemia (MHP). More than 200 mutations in the PAH gene are associated with PAH deficiency. From theoretical considerations or in vitro expre...

journal_title：European journal of pediatrics

authors： Güttler F,Guldberg P

更新日期：1996-07-01 00:00:00

abstract：:Clinically visible corneal opacities were observed in a patient with an extremely severe form of mucopolysaccharidosis II. In a second patient with an unusually mild form of mucopolysaccharidosis II, discrete corneal opacities were detected by slit-lamp examination. Thus clear corneae can no longer be regarded as a ha...

journal_title：European journal of pediatrics

authors： Spranger J,Cantz M,Gehler J,Liebaers I,Theiss W

更新日期：1978-08-17 00:00:00

abstract：INTRODUCTION:Reduced concentrations of glucose-6-phospate dehydrogenase (G6PD) render erythrocytes susceptible to hemolysis under conditions of oxidative stress. In favism, the ingestion of fava beans induces an oxidative stress to erythrocytes, leading to acute hemolysis. DISCUSSION:The simultaneous occurrence of met...

journal_title：European journal of pediatrics

authors： Schuurman M,van Waardenburg D,Da Costa J,Niemarkt H,Leroy P

更新日期：2009-07-01 00:00:00

abstract：UNLABELLED:In a Swiss screening programme for detection of congenital adrenal hyperplasia (CAH), 27 of over 120,000 newborns examined from 1992 to 1994 were further studied because of persistingly high 17 alpha hydroxyprogesterone (17OHP). Out of 27, 11 were later confirmed to have CAH by specific gas chromatography of...

journal_title：European journal of pediatrics

authors： Lange-Kubini K,Zachmann M,Kempken B,Torresani T

更新日期：1996-11-01 00:00:00

abstract：:Urinary tract infection (UTI) is a common bacterial infection among infants and children. Predicting which children with upper UTI will develop long-term sequelae remains difficult. We aimed at evaluating the predictive value of urine concentrations of interleukin-6 (UIL-6) and interleukin-8 (UIL-8) in subsequent rena...

journal_title：European journal of pediatrics

authors： Renata Y,Jassar H,Katz R,Hochberg A,Nir RR,Klein-Kremer A

更新日期：2013-06-01 00:00:00

abstract：:Portal hypertension was observed in a 17-year-old girl with urticaria pigmentosa since 2 months of age. Liver biopsies showed portal and sinusoidal infiltration with mast cells although spleen biopsies showed only fibrosis. CONCLUSION. Portal hypertension is a complication of systemic mastocytosis that can lead to dea...

journal_title：European journal of pediatrics

authors： Fonga-Djimi HS,Gottrand F,Bonnevalle M,Farriaux JP

更新日期：1995-10-01 00:00:00

abstract：UNLABELLED:Aldosterone synthase (P450c11AS) deficiency is a rare autosomal recessive disorder, presenting with severe salt-losing in early infancy. It is caused by inactivating mutations of the CYP11B2 gene. Here, we describe three unrelated Asian patients who have clinical and hormonal features compatible with aldoste...

journal_title：European journal of pediatrics

authors： Klomchan T,Supornsilchai V,Wacharasindhu S,Shotelersuk V,Sahakitrungruang T

更新日期：2012-10-01 00:00:00

abstract：:We updated our 2010 systematic review on the efficacy of probiotics in the treatment of constipation in children. The MEDLINE, EMBASE, and Cochrane Library databases; clinical trial registries; and reference lists of included studies were searched to February 2017 for randomized controlled trials (RCTs) performed in c...

journal_title：European journal of pediatrics

authors： Wojtyniak K,Szajewska H

更新日期：2017-09-01 00:00:00

abstract：:We studied the effects of an alginate compound (Gaviscon) on the frequency and the duration of gastroesophageal reflux (GOR) episodes in children. Twenty infants and children with characteristic symptoms of GOR were divided at random into two groups which were given either Gaviscon (ten patients, mean age: 21 months) ...

journal_title：European journal of pediatrics

authors： Buts JP,Barudi C,Otte JB

更新日期：1987-03-01 00:00:00

abstract：UNLABELLED:Patients diagnosed with intracranial teratoma are at risk for developing a recurrent malignant germ cell tumor. We describe a 14-year-old boy initially diagnosed with a mature teratoma in the pineal region that recurred as a metastatic beta-human chorionic gonadotropin (βHCG)-secreting germ cell tumor 3 year...

journal_title：European journal of pediatrics

authors： Cardellicchio S,Farina S,Buccoliero AM,Agresti B,Genitori L,de Martino M,Fangusaro J,Sardi I

更新日期：2014-08-01 00:00:00

abstract：:Paraneoplastic manifestations are signs and symptoms observed in patients with cancer, distant from the tumour or its metastases and not caused by invasion, obstruction or bulk mass. In children with cancer, paraneoplastic manifestations are rare and distinct from those observed in adults. Knowledge about paraneoplast...

journal_title：European journal of pediatrics

authors： de Graaf JH,Tamminga RY,Kamps WA

更新日期：1994-11-01 00:00:00

abstract：:Cardiac function is impaired in adults or children with hypothyroidism and it can be reversed by levothyroxine (L-T(4)) substitution therapy. However, only a few studies are available on left and right ventricular function in neonates with congenital hypothyroidism (CH), most of which were performed with standard echo...

journal_title：European journal of pediatrics

authors： Mao S,Wang Y,Jiang G,Zhao Z

更新日期：2007-12-01 00:00:00

abstract：:Cerebral blood flow velocities (CBFV) were measured by the pulsed Doppler method in 41 infants of smoking mothers and in 59 apparently healthy control infants. Although gestational age, birth weight, and systolic blood pressure were lower in infants exposed to tobacco smoke prenatally, systolic (65 +/- 11 vs. 47 +/- 1...

journal_title：European journal of pediatrics

authors： Abdul-Khaliq H,Segerer H,Luck W,Obladen M

更新日期：1993-03-01 00:00:00

abstract：:Chronic lung disease of prematurity (CLD) is a common respiratory disorder of preterm infants. At autopsy, fibroblast proliferation, and components of the extracellular matrix, including collagen and fibronectin, are markedly increased in the lungs of infants who die from CLD. Examination of broncho-alveolar fluid sug...

journal_title：European journal of pediatrics

authors： Kotecha S

更新日期：1996-08-01 00:00:00

abstract：:This review deals with podocyte proteins that play a significant role in the structure and function of the glomerular filter. Genetic linkage studies has identified several genes involved in the development of nephrotic syndrome and contributed to the understanding of the pathophysiology of glomerular proteinuria and/...

journal_title：European journal of pediatrics

authors： Löwik MM,Groenen PJ,Levtchenko EN,Monnens LA,van den Heuvel LP

更新日期：2009-11-01 00:00:00