Prazosin for nightmares in serious illness.

Abstract:

:Nightmares can be a distressing symptom in patients living with serious illness. Prazosin, a selective alpha-1 adrenergic antagonist, has been suggested to treat nightmares, with most data supporting its use in post-traumatic stress disorder (PTSD). We present the case of a 60-year-old woman with metastatic breast cancer who experienced healthcare-associated nightmares following hospitalisation. She did not meet diagnostic criteria for PTSD. Atypical antipsychotics and benzodiazepines were ineffective in controlling her nightmares, resulting in referral to our outpatient palliative medicine clinic. Prazosin was initiated alongside interdisciplinary psychosocial support, resulting in rapid resolution of her nightmares. To our knowledge, this is the first case to report on use of prazosin to manage nightmares in the outpatient palliative medicine setting.

authors

Santivasi W,Taylor E,Christensen A,Strand J

doi

10.1136/bmjspcare-2020-002594

subject

Has Abstract

pub_date

2021-01-27 00:00:00

eissn

2045-435X

issn

2045-4368

pii

bmjspcare-2020-002594

pub_type

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