Simulating thoughts to measure and study internal attention in mental health.

Abstract:

:Our mind's eye and the role of internal attention in mental life and suffering has intrigued scholars for centuries. Yet, experimental study of internal attention has been elusive due to our limited capacity to control the timing and content of internal stimuli. We thus developed the Simulated Thoughts Paradigm (STP) to experimentally deliver own-voice thought stimuli that simulate the content and experience of thinking and thereby experimental study of internal attentional processes. In independent experiments (N = 122) integrating STP into established cognitive-experimental tasks, we found and replicated evidence that emotional reactivity to negative thoughts predicts difficulty disengaging internal attention from, as well as biased selective internal attention of, those thoughts; these internal attention processes predict cognitive vulnerability (e.g., negative repetitive thinking) which thereby predict anxiety and depression. Proposed methods and findings may have implications for the study of information processing and attention in mental health broadly and models of internal attentional (dys)control in cognitive vulnerability and mental health more specifically.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Amir I,Ruimi L,Bernstein A

doi

10.1038/s41598-021-81756-w

subject

Has Abstract

pub_date

2021-01-26 00:00:00

pages

2251

issue

1

issn

2045-2322

pii

10.1038/s41598-021-81756-w

journal_volume

11

pub_type

杂志文章
  • Differential Scanning Fluorimetry provides high throughput data on silk protein transitions.

    abstract::Here we present a set of measurements using Differential Scanning Fluorimetry (DSF) as an inexpensive, high throughput screening method to investigate the folding of silk protein molecules as they abandon their first native melt conformation, dehydrate and denature into their final solid filament conformation. Our fir...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep05625

    authors: Vollrath F,Hawkins N,Porter D,Holland C,Boulet-Audet M

    更新日期:2014-07-09 00:00:00

  • Evidence of a Causal Role for mid-Ventrolateral Prefrontal Cortex Based Functional Networks in Retrieving High-Fidelity Memory.

    abstract::Functional neuroimaging studies have implicated regions of both ventrolateral prefrontal cortex (VLPFC) and angular gyrus in processes associated with retrieving goal-relevant information, which increases the fidelity and richness of long-term memory (LTM). To further investigate the roles of these cortical regions as...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-33164-w

    authors: Wais PE,Montgomery O,Stark CEL,Gazzaley A

    更新日期:2018-10-05 00:00:00

  • De Novo Design of Potent, Insecticidal Synthetic Mimics of the Spinosyn Macrolide Natural Products.

    abstract::New insect pest control agents are needed to meet the demands to feed an expanding global population, to address the desire for more environmentally-friendly insecticide tools, and to fill the loss of control options in some crop-pest complexes due to development of insecticide resistance. The spinosyns are a highly e...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-22894-6

    authors: Crouse GD,Demeter DA,Samaritoni G,McLeod CL,Sparks TC

    更新日期:2018-03-20 00:00:00

  • The Dynamics of Nanoparticle-enhanced Fluid Displacement in Porous Media - A Pore-scale Study.

    abstract::This work provides new insights into the dynamics of silica nanoparticle-based removal of organic fluids (here oil) from naturally occurring porous media. We have used 4D (time-resolved 3D) imaging at pore-scale using X-ray computed micro-tomography (μCT) technique. The captured 3D tomographic time-series data reveal ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-29569-2

    authors: Pak T,Archilha NL,Mantovani IF,Moreira AC,Butler IB

    更新日期:2018-07-24 00:00:00

  • The Generalization of Auditory Accommodation to Altered Spectral Cues.

    abstract::The capacity of healthy adult listeners to accommodate to altered spectral cues to the source locations of broadband sounds has now been well documented. In recent years we have demonstrated that the degree and speed of accommodation are improved by using an integrated sensory-motor training protocol under anechoic co...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-11981-9

    authors: Watson CJG,Carlile S,Kelly H,Balachandar K

    更新日期:2017-09-14 00:00:00

  • Author Correction: Carbon nanotubes promote cell migration in hydrogels.

    abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

    journal_title:Scientific reports

    pub_type: 已发布勘误

    doi:10.1038/s41598-020-62443-8

    authors: Ravanbakhsh H,Bao G,Mongeau L

    更新日期:2020-03-24 00:00:00

  • Genomic and phenotypic analysis of Vavilov's historic landraces reveals the impact of environment and genomic islands of agronomic traits.

    abstract::The Vavilov Institute of Plant Genetic Resources (VIR), in St. Petersburg, Russia, houses a unique genebank, with historical collections of landraces. When they were collected, the geographical distribution and genetic diversity of most crops closely reflected their historical patterns of cultivation established over ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-05087-5

    authors: Plekhanova E,Vishnyakova MA,Bulyntsev S,Chang PL,Carrasquilla-Garcia N,Negash K,Wettberg EV,Noujdina N,Cook DR,Samsonova MG,Nuzhdin SV

    更新日期:2017-07-06 00:00:00

  • Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface.

    abstract::The mechanism by which the HIV-1 MPER epitope is recognized by the potent neutralizing antibody 10E8 at membrane interfaces remains poorly understood. To solve this problem, we have optimized a 10E8 peptide epitope and analyzed the structure and binding activities of the antibody in membrane and membrane-like environm...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep38177

    authors: Rujas E,Caaveiro JM,Partida-Hanon A,Gulzar N,Morante K,Apellániz B,García-Porras M,Bruix M,Tsumoto K,Scott JK,Jiménez MÁ,Nieva JL

    更新日期:2016-12-01 00:00:00

  • Dynamical transitions during the collapse of inertial holes.

    abstract::At the center of a collapsing hole lies a singularity, a point of infinite curvature where the governing equations break down. It is a topic of fundamental physical interest to clarify the dynamics of fluids approaching such singularities. Here, we use scaling arguments supported by high-fidelity simulations to analyz...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-50956-w

    authors: Lu J,Corvalan CM

    更新日期:2019-10-10 00:00:00

  • Aspirin might reduce the incidence of pancreatic cancer: A meta-analysis of observational studies.

    abstract::Although there is evidence that non-steroidal anti-inflammatory drugs (NSAIDs) might be able to prevent pancreatic cancer, the findings from epidemiological studies have been inconsistent. In this paper, we conducted a meta-analysis of observational studies to examine this possibility. We searched PubMed and Embase fo...

    journal_title:Scientific reports

    pub_type: 杂志文章,meta分析

    doi:10.1038/srep15460

    authors: Zhang YP,Wan YD,Sun YL,Li J,Zhu RT

    更新日期:2015-10-21 00:00:00

  • Modeling the binding of diverse ligands within the Ah receptor ligand binding domain.

    abstract::The Ah receptor (AhR) is a ligand-dependent transcription factor belonging to the basic helix-loop-helix Per-Arnt-Sim (bHLH-PAS) superfamily. Binding to and activation of the AhR by a variety of chemicals results in the induction of expression of diverse genes and production of a broad spectrum of biological and toxic...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-47138-z

    authors: Giani Tagliabue S,Faber SC,Motta S,Denison MS,Bonati L

    更新日期:2019-07-23 00:00:00

  • Deciphering host lysosome-mediated elimination of Plasmodium berghei liver stage parasites.

    abstract::Liver stage Plasmodium parasites reside in a parasitophorous vacuole (PV) that associates with lysosomes. It has previously been shown that these organelles can have beneficial as well as harmful effects on the parasite. Yet it is not clear how the association of lysosomes with the parasite is controlled and how inter...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-44449-z

    authors: Niklaus L,Agop-Nersesian C,Schmuckli-Maurer J,Wacker R,Grünig V,Heussler VT

    更新日期:2019-05-28 00:00:00

  • Contribution of BH3-domain and Transmembrane-domain to the Activity and Interaction of the Pore-forming Bcl-2 Proteins Bok, Bak, and Bax.

    abstract::Central to intrinsic apoptosis signaling is the release of cytochrome c from mitochondria, which depends on the pro-apoptotic effector proteins Bax, Bak or Bok. These pore-forming effector proteins share four Bcl-2 homology (BH) domains, a functionally essential and conserved sequence of hydrophobic amino acids in the...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-30603-6

    authors: Stehle D,Grimm M,Einsele-Scholz S,Ladwig F,Johänning J,Fischer G,Gillissen B,Schulze-Osthoff K,Essmann F

    更新日期:2018-08-20 00:00:00

  • NLRX1 accelerates cisplatin-induced ototoxity in HEI-OC1 cells via promoting generation of ROS and activation of JNK signaling pathway.

    abstract::Nucleotide-binding domain and leucine-rich-repeat-containing family member X1 (NLRX1), located in mitochondria, can recognize cytoplasmic pattern recognition receptors and is tightly related to reactive oxygen species (ROS) production, mitochondrial function, apoptosis and inflammation. The present study was designed ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep44311

    authors: Yin H,Sun G,Yang Q,Chen C,Qi Q,Wang H,Li J

    更新日期:2017-03-13 00:00:00

  • Soliton-induced relativistic-scattering and amplification.

    abstract::Solitons are of fundamental importance in photonics due to applications in optical data transmission and also as a tool for investigating novel phenomena ranging from light generation at new frequencies and wave-trapping to rogue waves. Solitons are also moving scatterers: they generate refractive index perturbations ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep00932

    authors: Rubino E,Lotti A,Belgiorno F,Cacciatori SL,Couairon A,Leonhardt U,Faccio D

    更新日期:2012-01-01 00:00:00

  • Coronary micro-computed tomography angiography in mice.

    abstract::Coronary computed tomography angiography is an established technique in clinical practice and a valuable tool in the diagnosis of coronary artery disease in humans. Imaging of coronaries in preclinical research, i.e. in small animals, is very difficult due to the high demands on spatial and temporal resolution. Mice e...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-73735-4

    authors: Sawall S,Beckendorf J,Amato C,Maier J,Backs J,Vande Velde G,Kachelrieß M,Kuntz J

    更新日期:2020-10-08 00:00:00

  • Redox balance, metabolic fingerprint and physiological characterization in contrasting North East Indian rice for Aluminum stress tolerance.

    abstract::Aluminum (Al) toxicity is a serious problem for rice crop productivity in acidic soils worldwide. The present work was conducted to look out for the alteration in ROS homeostasis; metabolic fingerprint; and morphology in two contrasting Indica rice cultivars of North East India (NE India) to Al toxicity. Al stress led...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-45158-3

    authors: Awasthi JP,Saha B,Panigrahi J,Yanase E,Koyama H,Panda SK

    更新日期:2019-06-18 00:00:00

  • Respiratory tract infections among French Hajj pilgrims from 2014 to 2017.

    abstract::Respiratory tract infections (RTIs) are common among Hajj pilgrims, but risk factors for RTIs and respiratory pathogen acquisition during the Hajj are not clearly identified. Based on previous studies, most frequent pathogens acquired by Hajj pilgrims were investigated: rhinovirus, human coronaviruses, influenza virus...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-54370-0

    authors: Hoang VT,Ali-Salem S,Belhouchat K,Meftah M,Sow D,Dao TL,Ly TDA,Drali T,Ninove L,Yezli S,Alotaibi B,Raoult D,Parola P,Pommier de Santi V,Gautret P

    更新日期:2019-11-28 00:00:00

  • Author Correction: Inter-ocular and inter-visit differences in ocular biometry and refractive outcomes after cataract surgery.

    abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

    journal_title:Scientific reports

    pub_type: 已发布勘误

    doi:10.1038/s41598-020-75647-9

    authors: Choi HS,Yoo HS,An Y,Yoon SY,Park SP,Kim YK

    更新日期:2020-10-29 00:00:00

  • Neuroprotective effects of a Coeloglossum viride var. Bracteatum extract in vitro and in vivo.

    abstract::The excessive release and accumulation of glutamate in the brain is known to be associated with excitotoxicity. CE, an extract derived from the plant Coeloglossum viride var. Bracteatum, exerted neuroprotective effects against amyloid toxicity and oxidative stress in cortical neurons. The aims of this study are to exa...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-08957-0

    authors: Pan RY,Ma J,Wu HT,Liu QS,Qin XY,Cheng Y

    更新日期:2017-08-23 00:00:00

  • Application of a Limit-Cycle Oscillator Model for Prediction of Circadian Phase in Rotating Night Shift Workers.

    abstract::Practical alternatives to gold-standard measures of circadian timing in shift workers are needed. We assessed the feasibility of applying a limit-cycle oscillator model of the human circadian pacemaker to estimate circadian phase in 25 nursing and medical staff in a field setting during a transition from day/evening s...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-47290-6

    authors: Stone JE,Aubert XL,Maass H,Phillips AJK,Magee M,Howard ME,Lockley SW,Rajaratnam SMW,Sletten TL

    更新日期:2019-07-30 00:00:00

  • Author Correction: Early‑life short‑term environmental enrichment counteracts the effects of stress on anxiety‑like behavior, brain‑derived neurotrophic factor and nuclear translocation of glucocorticoid receptors in the basolateral amygdala.

    abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

    journal_title:Scientific reports

    pub_type: 已发布勘误

    doi:10.1038/s41598-020-74322-3

    authors: Hegde A,Suresh S,Mitra R

    更新日期:2020-10-06 00:00:00

  • Metabolomics of Eothenomys miletus from five Hengduan Mountains locations in summer.

    abstract::Climatic characteristics of Hengduan Mountains region were diverse, and Eothenomys miletus was a native species throughout this region. To investigate adaptive strategies of E. miletus to environmental factors in different locations in this region, five locations were selected, including Deqin (DQ), Xianggelila (XGLL)...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-51493-2

    authors: Zhang HJ,Wang ZK,Zhu WL

    更新日期:2019-10-17 00:00:00

  • Comparing Sanger sequencing and high-throughput metabarcoding for inferring photobiont diversity in lichens.

    abstract::The implementation of HTS (high-throughput sequencing) approaches is rapidly changing our understanding of the lichen symbiosis, by uncovering high bacterial and fungal diversity, which is often host-specific. Recently, HTS methods revealed the presence of multiple photobionts inside a single thallus in several lichen...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-26947-8

    authors: Paul F,Otte J,Schmitt I,Dal Grande F

    更新日期:2018-06-05 00:00:00

  • ZFP226 is a novel artificial transcription factor for selective activation of tumor suppressor KIBRA.

    abstract::KIBRA has been suggested as a key regulator of the hippo pathway, regulating organ size, cell contact inhibition as well as tissue regeneration and tumorigenesis. Recently, alterations of KIBRA expression caused by promotor methylation have been reported for several types of cancer. Our current study aimed to design a...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-22600-6

    authors: Schelleckes K,Schmitz B,Lenders M,Mewes M,Brand SM,Brand E

    更新日期:2018-03-09 00:00:00

  • Impedance-based analysis of Natural Killer cell stimulation.

    abstract::The use of impedance-based label free cell analysis is increasingly popular and has many different applications. Here, we report that a real-time cell analyzer (RTCA) can be used to study the stimulation of Natural Killer (NK) cells. Engagement of NK cells via plate-bound antibodies directed against different activati...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-23368-5

    authors: Fasbender F,Watzl C

    更新日期:2018-03-21 00:00:00

  • Bioelectronic interfaces by spontaneously organized peptides on 2D atomic single layer materials.

    abstract::Self-assembly of biological molecules on solid materials is central to the "bottom-up" approach to directly integrate biology with electronics. Inspired by biology, exquisite biomolecular nanoarchitectures have been formed on solid surfaces. We demonstrate that a combinatorially-selected dodecapeptide and its variants...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep33778

    authors: Hayamizu Y,So CR,Dag S,Page TS,Starkebaum D,Sarikaya M

    更新日期:2016-09-22 00:00:00

  • Microsecond time-resolved energy-dispersive EXAFS measurement and its application to film the thermolysis of (NH₄)₂[PtCl₆].

    abstract::Microsecond (μs) time-resolved extended X-ray absorption fine structure spectroscopy (EXAFS) has been developed using an energy-dispersive EXAFS (EDE) setup equipped with a silicon Quantum Detector ULTRA. The feasibility was investigated with a prototypical thermally driven redox reaction, the thermal decomposition of...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep01018

    authors: Kong Q,Baudelet F,Han J,Chagnot S,Barthe L,Headspith J,Goldsbrough R,Picca FE,Spalla O

    更新日期:2012-01-01 00:00:00

  • Validation of the Drug Abuse Screening Test (DAST-10): A study on illicit drug use among Chinese pregnant women.

    abstract::We assessed the Chinese version of the Drug Abuse Screening Test (DAST-10) for identifying illicit drug use during pregnancy among Chinese population. Chinese pregnant women attending their first antenatal visit or their first unbooked visit to the maternity ward were recruited during a 4-month study period in 2011. T...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep11420

    authors: Lam LP,Leung WC,Ip P,Chow CB,Chan MF,Ng JW,Sing C,Lam YH,Mak WL,Chow KM,Chin RK

    更新日期:2015-06-19 00:00:00

  • Performance of Deep Learning Architectures and Transfer Learning for Detecting Glaucomatous Optic Neuropathy in Fundus Photographs.

    abstract::The ability of deep learning architectures to identify glaucomatous optic neuropathy (GON) in fundus photographs was evaluated. A large database of fundus photographs (n = 14,822) from a racially and ethnically diverse group of individuals (over 33% of African descent) was evaluated by expert reviewers and classified ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-35044-9

    authors: Christopher M,Belghith A,Bowd C,Proudfoot JA,Goldbaum MH,Weinreb RN,Girkin CA,Liebmann JM,Zangwill LM

    更新日期:2018-11-12 00:00:00