Efficacy of Hemostatic Gauzes in a Swine Model of Prolonged Field Care with Limb Movement.

Abstract:

INTRODUCTION:Prolonged field care for junctional wounds is challenging and involves limb movement to facilitate transport. No studies to date have explored the efficacy of gauze products to limit rebleeding in these scenarios. MATERIALS AND METHODS:We randomly assigned 48 swine to QuikClot Combat Gauze, ChitoGauze, NuStat Tactical, or Kerlix treatment groups (12 each) and then inflicted a severe groin injury by utilizing a modified Kheirabadi model of a 6-mm femoral artery punch followed by unrestricted bleeding for 60 seconds. We reassessed rebleed following limb movement at 30 minutes of stabilization and 4 hours after stabilization. RESULTS:Swine treated with Combat Gauze proved to have the lowest incidence of rebleeding, and conversely, NuStat Tactical had the highest incidence of rebleeding at wounds after limb movement. Importantly, rebleeds occurred at a rate of 25%-58% across all swine treatment groups at 30 minutes postinjury and 0%-42% at 270 minutes postinjury demonstrating that limb movements universally challenge hemostatic junctional wounds. CONCLUSIONS:Our findings highlight the difficulty of controlling hemorrhage from junctional wounds with hemostatic gauze in the context of prolonged field care and casualty transport. Our research can guide selection of hemorrhage control gauze when patients have prolonged field extraction or difficult transport. Our data demonstrates the frequency of junctional wound rebleeding after movement and thus the importance of frequent patient reassessment.

journal_name

Mil Med

journal_title

Military medicine

authors

Landers GD,Townsend C,Gaspary M,Kachur R,Thorne B,Stuart S,Henao J,Zarow GJ,Natarajan R,Boboc M

doi

10.1093/milmed/usaa403

subject

Has Abstract

pub_date

2021-01-25 00:00:00

pages

384-390

issue

Suppl 1

eissn

0026-4075

issn

1930-613X

pii

6119467

journal_volume

186

pub_type

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