Abstract:
BACKGROUND:Active principles from natural sources, in the form of extracts and natural compounds, provide an infinite number of bioactive compounds with consummate disposal of chemical diversity. These compounds and active principles are of utmost importance in the discovery of drugs of biological origin particularly, from plants. OBJECTIVE:Development of resourceful technology for the isolation and extraction of bioactive compounds of medicinal importance is considered as an important task for researchers. There are a number of extraction, isolation, and characterization techniques currently utilized; however, most are laborious and use toxic chemicals and huge quantities of raw materials with a very low output. There are a number of abiotic and biotic factors that affects the quality and the quantity of plants bioactive compounds. Considering this the objectives of the current review is to discuss the various extraction and characterization techniques used to isolate the essential bioactive compounds from three plant species and the biotic and abiotic factors that affects the quantity and quality of the plants secondary metabolites. METHODS:Many advanced technologies have been developed and tested for extraction, characterization, and their capacity for high yield products, and those requiring less application of toxic solvents are investigated continuously. CONCLUSION:In this context, the present review summarizes the different types of extraction and characterization techniques utilized commercially by the food, drug, and pharmaceutical industries for better output and environmentally- and healthbenefiting products with special reference to three industrially important plants: Leonotis leonurus (L.) R.Br. (Lamiaceae) and Santalum album L. (Santalaceae) and Aloe vera (L.) Burm. f. (Aloaceae or Asphodelaceae).
journal_name
Curr Pharm Biotechnoljournal_title
Current pharmaceutical biotechnologyauthors
Das G,Patra JK,Kang SS,Shin HSdoi
10.2174/1389201022666210122125854subject
Has Abstractpub_date
2021-01-22 00:00:00eissn
1389-2010issn
1873-4316pii
CPB-EPUB-113571pub_type
杂志文章abstract::Hepatocellular carcinoma (HCC) represents the third cause of cancer-related death. Because HCC is multi-centric with time, excluding the few transplanted patients, sooner or later it becomes untreatable with loco-regional therapies and, until some years ago, it was not responsive to systemic therapies. In 2005 a rando...
journal_title:Current pharmaceutical biotechnology
pub_type: 杂志文章
doi:10.2174/138920111794295855
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abstract:BACKGROUND:Enterotoxigenic Escherichia coli (ETEC) is the main cause of fatal diarrhea in piglets during the first week of life and over the time of weaning. Pathogenesis of ETEC-causing diarrhea involves intestinal colonization mediated by fimbriae. Although, both IgY and egg yolk phosvitin (PV) possess antimicrobial ...
journal_title:Current pharmaceutical biotechnology
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journal_title:Current pharmaceutical biotechnology
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journal_title:Current pharmaceutical biotechnology
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journal_title:Current pharmaceutical biotechnology
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更新日期:2014-01-01 00:00:00
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journal_title:Current pharmaceutical biotechnology
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journal_title:Current pharmaceutical biotechnology
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更新日期:2015-01-01 00:00:00
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journal_title:Current pharmaceutical biotechnology
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journal_title:Current pharmaceutical biotechnology
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journal_title:Current pharmaceutical biotechnology
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journal_title:Current pharmaceutical biotechnology
pub_type: 杂志文章,评审
doi:10.2174/138920105775159304
更新日期:2005-12-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.2174/1389201020666181227150829
更新日期:2018-01-01 00:00:00
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更新日期:2020-01-01 00:00:00
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更新日期:2019-01-01 00:00:00
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journal_title:Current pharmaceutical biotechnology
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更新日期:2000-12-01 00:00:00
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journal_title:Current pharmaceutical biotechnology
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更新日期:2012-05-01 00:00:00
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journal_title:Current pharmaceutical biotechnology
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更新日期:2012-06-01 00:00:00
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journal_title:Current pharmaceutical biotechnology
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更新日期:2020-09-27 00:00:00
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journal_title:Current pharmaceutical biotechnology
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更新日期:2012-09-01 00:00:00
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更新日期:2016-01-01 00:00:00
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journal_title:Current pharmaceutical biotechnology
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更新日期:2011-02-01 00:00:00
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journal_title:Current pharmaceutical biotechnology
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更新日期:2019-01-01 00:00:00
abstract::Pulmonary fibrosis is an unremitting degenerative lung disease that has an associated high mortality. The major pathological features include the growth of fibroblasts, emergence of myofibroblasts and their production of extracellular matrix that distorts the peripheral lung tissue and impairs respiratory function. Ef...
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doi:10.2174/138920111798281045
更新日期:2011-09-01 00:00:00