当前位置： SCI文献检索 > NEUROIMAGE期刊下所有文献 > A ventral striatal prediction error signal in human fear extinction learning.

A ventral striatal prediction error signal in human fear extinction learning.

Abstract：

:Animal studies have shown that the prediction error (PE) signal that drives fear extinction learning is encoded by phasic activity of midbrain dopamine (DA) neurons. Thus, the extinction PE resembles the appetitive PE that drives reward learning. In humans, fear extinction learning is less well understood. Using computational neuroimaging, a previous study from our group reported hemodynamic activity in the left ventral putamen, a subregion of the ventral striatum (VS), to correlate with a PE function derived from a formal associative learning model. The activity was modulated by genetic variation in a DA-related gene. To conceptually replicate and extend this finding, we here asked whether an extinction PE (EPE) signal in the left ventral putamen can also be observed when genotype information is not taken into account. Using an optimized experimental design for model estimation, we again observed EPE-related activity in the same striatal region, indicating that activation of this region is a feature of human extinction learning. We further observed significant EPE signals across wider parts of the VS as well as in frontal cortical areas. These results may suggest that the prediction errors during extinction learning are available to larger parts of the brain, as has also been observed in human neuroimaging studies of reward PE signaling. Conclusive evidence that the human EPE signal is of DAergic nature is still outstanding.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Thiele M,Yuen KSL,Gerlicher AVM,Kalisch R

doi

10.1016/j.neuroimage.2020.117709

subject

Has Abstract

pub_date

2021-01-15 00:00:00

pages

117709

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(20)31194-0

journal_volume

229

pub_type

杂志文章

相关文献

NEUROIMAGE文献大全
  • A cross-validated cytoarchitectonic atlas of the human ventral visual stream.

    abstract：:The human ventral visual stream consists of several areas that are considered processing stages essential for perception and recognition. A fundamental microanatomical feature differentiating areas is cytoarchitecture, which refers to the distribution, size, and density of cells across cortical layers. Because cytoarc...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.02.040

    authors： Rosenke M,Weiner KS,Barnett MA,Zilles K,Amunts K,Goebel R,Grill-Spector K

    更新日期：2018-04-15 00:00:00

  • Localization of extended brain sources from EEG/MEG: the ExSo-MUSIC approach.

    abstract：:We propose a new MUSIC-like method, called 2q-ExSo-MUSIC (q ≥ 1). This method is an extension of the 2q-MUSIC (q ≥ 1) approach for solving the EEG/MEG inverse problem, when spatially-extended neocortical sources ("ExSo") are considered. It introduces a novel ExSo-MUSIC principle. The novelty is two-fold: i) the parame...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2011.01.054

    authors： Birot G,Albera L,Wendling F,Merlet I

    更新日期：2011-05-01 00:00:00

  • Brain imaging signatures of the relationship between epidermal nerve fibers and heat pain perception.

    abstract：:Although the small-diameter primary afferent fibers in the skin promptly respond to nociceptive stimuli and convey sensory inputs to the central nervous system, the neural signatures that underpin the relationship between cutaneous afferent fibers and pain perception remain elusive. We combined skin biopsy at the late...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.08.021

    authors： Tseng MT,Kong Y,Chiang MC,Chao CC,Tseng WY,Hsieh ST

    更新日期：2015-11-15 00:00:00

  • Left hemisphere lateralization for lexical and acoustic pitch processing in Cantonese speakers as revealed by mismatch negativity.

    abstract：:For nontonal language speakers, speech processing is lateralized to the left hemisphere and musical processing is lateralized to the right hemisphere (i.e., function-dependent brain asymmetry). On the other hand, acoustic temporal processing is lateralized to the left hemisphere and spectral/pitch processing is latera...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.02.080

    authors： Gu F,Zhang C,Hu A,Zhao G

    更新日期：2013-12-01 00:00:00

  • Waxholm space: an image-based reference for coordinating mouse brain research.

    abstract：:We describe an atlas of the C57BL/6 mouse brain based on MRI and conventional Nissl histology. Magnetic resonance microscopy was performed on a total of 14 specimens that were actively stained to enhance tissue contrast. Images were acquired with three different MR protocols yielding contrast dependent on spin lattice...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.06.067

    authors： Johnson GA,Badea A,Brandenburg J,Cofer G,Fubara B,Liu S,Nissanov J

    更新日期：2010-11-01 00:00:00

  • First demonstration of in vivo mapping for regional brain monoacylglycerol lipase using PET with [11C]SAR127303.

    abstract：:Monoacylglycerol lipase (MAGL) is a main regulator of the endocannabinoid system within the central nervous system (CNS). Recently, [11C]SAR127303 was developed as a promising radioligand for MAGL imaging. In this study, we aimed to quantify regional MAGL concentrations in the rat brain using positron emission tomogra...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2018.05.015

    authors： Yamasaki T,Mori W,Zhang Y,Hatori A,Fujinaga M,Wakizaka H,Kurihara Y,Wang L,Nengaki N,Ohya T,Liang SH,Zhang MR

    更新日期：2018-08-01 00:00:00

  • Searching for behavior relating to grey matter volume in a-priori defined right dorsal premotor regions: Lessons learned.

    abstract：:Recently, we showed that the functional heterogeneity of the right dorsal premotor (PMd) cortex could be better understood by dividing it into five subregions that showed different behavioral associations according to task-based activations studies. The present study investigated whether the revealed behavioral profil...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.05.053

    authors： Genon S,Wensing T,Reid A,Hoffstaedter F,Caspers S,Grefkes C,Nickl-Jockschat T,Eickhoff SB

    更新日期：2017-08-15 00:00:00

  • Specialisation in Broca's region for semantic, phonological, and syntactic fluency?

    abstract：:The literature suggests that that semantic and phonological fluency tasks selectively activate left Brodmann's area (BA) 45 and 44, respectively, in Broca's speech region. We used functional MRI to test this hypothesis. Subjects performed a semantic and a phonological fluency task. In addition, a syntactic fluency tas...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.01.009

    authors： Heim S,Eickhoff SB,Amunts K

    更新日期：2008-04-15 00:00:00

  • Characterization of the cortical myeloarchitecture with inhomogeneous magnetization transfer imaging (ihMT).

    abstract：BACKGROUND:Myelin specific imaging techniques to characterize white matter in demyelinating diseases such as multiple sclerosis (MS) have become an area of increasing focus. Gray matter myelination is an important marker of cortical microstructure, and its impairment is relevant in progressive MS. However, its assessme...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2020.117442

    authors： Munsch F,Varma G,Taso M,Girard O,Guidon A,Duhamel G,Alsop DC

    更新日期：2021-01-15 00:00:00

  • Distinct representations for facial identity and changeable aspects of faces in the human temporal lobe.

    abstract：:The neural system underlying face perception must represent the unchanging features of a face that specify identity, as well as the changeable aspects of a face that facilitate social communication. However, the way information about faces is represented in the brain remains controversial. In this study, we used fMR a...

    journal_title：NeuroImage

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.neuroimage.2004.07.060

    authors： Andrews TJ,Ewbank MP

    更新日期：2004-11-01 00:00:00

  • Brain default-mode network dysfunction in addiction.

    abstract：:Aberrant patterns of brain functional connectivity in the default mode network (DMN) have been observed across different classes of substance use disorder (SUD) and are associated with craving and relapse. In addicted individuals resting functional connectivity (RSFC) of the anterior DMN, which participates in attribu...

    journal_title：NeuroImage

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuroimage.2019.06.036

    authors： Zhang R,Volkow ND

    更新日期：2019-10-15 00:00:00

  • Comparison of [(11)C]-(R)-PK 11195 and [(11)C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker.

    abstract：UNLABELLED:Ten percent of humans lack specific binding of [(11)C]PBR28 to 18 kDa translocator protein (TSPO), a biomarker for inflammation. "Non-binders" have not been reported using another TSPO radioligand, [(11)C]-(R)-PK 11195, despite its use for more than two decades. This study asked two questions: (1) What is th...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.11.056

    authors： Kreisl WC,Fujita M,Fujimura Y,Kimura N,Jenko KJ,Kannan P,Hong J,Morse CL,Zoghbi SS,Gladding RL,Jacobson S,Oh U,Pike VW,Innis RB

    更新日期：2010-02-15 00:00:00

  • The effect of gender on planning: An fMRI study using the Tower of London task.

    abstract：:Since the introduction of brain mapping, evidences of functional gender differences have been corroborating previous behavioral and neuropsychological results showing a sex-specific brain organization. We investigated gender differences in brain activation during the performance of the Tower of London (TOL) task which...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.07.022

    authors： Boghi A,Rasetti R,Avidano F,Manzone C,Orsi L,D'Agata F,Caroppo P,Bergui M,Rocca P,Pulvirenti L,Bradac GB,Bogetto F,Mutani R,Mortara P

    更新日期：2006-11-15 00:00:00

  • Layer-specific response properties of the human lateral geniculate nucleus and superior colliculus.

    abstract：:The human LGN and SC consist of distinct layers, but their layer-specific response properties remain poorly understood. In this fMRI study, we characterized visual response properties of the magnocellular (M) and parvocellular (P) layers of the human LGN, as well as at different depths in the SC. Results show that fMR...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.02.025

    authors： Zhang P,Zhou H,Wen W,He S

    更新日期：2015-05-01 00:00:00

  • A functional anatomy of anticipatory anxiety.

    abstract：:Anticipatory anxiety is a complex combination of a future-oriented cognitive state, negative affect, and autonomic arousal. A dual-task paradigm of anticipation of electric shocks and a motor-learning task was used to examine the changes in neural patterns of activation associated with modulation of the cognitive stat...

    journal_title：NeuroImage

    pub_type： 临床试验,杂志文章

    doi：10.1006/nimg.1999.0407

    authors： Chua P,Krams M,Toni I,Passingham R,Dolan R

    更新日期：1999-06-01 00:00:00

  • Size and probability of rewards modulate the feedback error-related negativity associated with wins but not losses in a monetarily rewarded gambling task.

    abstract：:Feedback error-related negativity (fERN) has been referred to as a negative deflection in the event related potential (ERP), which distinguishes between wins and losses in terms of expected and unexpected outcomes. Some studies refer to the "expected outcome" as the probability to win vs. to lose, and others as expect...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.03.031

    authors： San Martín R,Manes F,Hurtado E,Isla P,Ibañez A

    更新日期：2010-07-01 00:00:00

  • High-resolution fluorescence microscopy of myelin without exogenous probes.

    abstract：:Myelin is a critical element of the central and peripheral nervous systems of all higher vertebrates. Any disturbance in the integrity of the myelin sheath interferes with the axon's ability to conduct action potentials. Thus, the study of myelin structure and biochemistry is critically important. Accurate and even st...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.10.050

    authors： Christensen PC,Brideau C,Poon KW,Döring A,Yong VW,Stys PK

    更新日期：2014-02-15 00:00:00

  • Characterizing function-structure relationships in the human visual system with functional MRI and diffusion tensor imaging.

    abstract：:A key objective in neuroscience is to improve our understanding of the relationship between brain function and structure. We investigated this in the posterior visual pathways of healthy volunteers by applying functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) with tractography. The optic ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2003.11.022

    authors： Toosy AT,Ciccarelli O,Parker GJ,Wheeler-Kingshott CA,Miller DH,Thompson AJ

    更新日期：2004-04-01 00:00:00

  • Attention-dependent changes of activation and connectivity in dichotic listening.

    abstract：:Functional studies of auditory spatial attention generally report enhanced neural responses in auditory cortical regions. However, activity in regions of the spatial attentional network as described in the visual modality is not consistently observed. Data analysis limitations due to oppositely lateralized activity de...

    journal_title：NeuroImage

    pub_type： 临床试验,杂志文章

    doi：

    authors： Lipschutz B,Kolinsky R,Damhaut P,Wikler D,Goldman S

    更新日期：2002-10-01 00:00:00

  • BOLD correlates of EMG spectral density in cortical myoclonus: description of method and case report.

    abstract：:The recording of electrophysiological data during BOLD fMRI is highly challenging but provides the opportunity to develop a more thorough account of brain function than either modality alone. To develop new techniques in this area has often required the study of pathological electrophysiological measures because such ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.04.183

    authors： Richardson MP,Grosse P,Allen PJ,Turner R,Brown P

    更新日期：2006-08-15 00:00:00

  • Functional MRI evidence for disparate developmental processes underlying intelligence in boys and girls.

    abstract：:Previous research has shown evidence for sex differences in the neuroanatomical bases for intelligence in adults. Possible differences in the neuroanatomical correlates of intelligence and their developmental trajectories between boys and girls were investigated using functional MRI (fMRI). A large cohort of over 300 ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.01.010

    authors： Schmithorst VJ,Holland SK

    更新日期：2006-07-01 00:00:00

  • Development of the default-mode network during childhood and adolescence: A longitudinal resting-state fMRI study.

    abstract：:The default-mode network (DMN) is a set of functionally connected regions that play crucial roles in internal cognitive processing. Previous resting-state fMRI studies have demonstrated that the intrinsic functional organization of the DMN undergoes remarkable reconfigurations during childhood and adolescence. However...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2020.117581

    authors： Fan F,Liao X,Lei T,Zhao T,Xia M,Men W,Wang Y,Hu M,Liu J,Qin S,Tan S,Gao JH,Dong Q,Tao S,He Y

    更新日期：2021-02-01 00:00:00

  • Understanding the functional neuroanatomy of acquired prosopagnosia.

    abstract：:One of the most remarkable disorders following brain damage is prosopagnosia, the inability to recognize faces. While a number of cases of prosopagnosia have been described at the behavioral level, the functional neuroanatomy of this face recognition impairment, and thus the brain regions critically involved in normal...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.09.051

    authors： Sorger B,Goebel R,Schiltz C,Rossion B

    更新日期：2007-04-01 00:00:00

  • Identifying population differences in whole-brain structural networks: a machine learning approach.

    abstract：:Models of whole-brain connectivity are valuable for understanding neurological function, development and disease. This paper presents a machine learning based approach to classify subjects according to their approximated structural connectivity patterns and to identify features which represent the key differences betw...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.01.019

    authors： Robinson EC,Hammers A,Ericsson A,Edwards AD,Rueckert D

    更新日期：2010-04-15 00:00:00

  • Role of the human retrosplenial cortex/parieto-occipital sulcus in perspective priming.

    abstract：:The ability to imagine the world from a different viewpoint is a fundamental competence for spatial reorientation and for imagining what another individual sees in the environment. Here, we investigated the neural bases of such an ability using functional magnetic resonance imaging. Healthy participants detected targe...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2015.10.040

    authors： Sulpizio V,Committeri G,Lambrey S,Berthoz A,Galati G

    更新日期：2016-01-15 00:00:00

  • Voxel-based morphometry to detect brain atrophy in progressive mild cognitive impairment.

    abstract：:Recent research has shown an increased rate of conversion to dementia in subjects with mild cognitive impairment (MCI) compared to controls. However, there are no specific methods to predict who will later develop dementia. In the present study, 22 controls and 56 MCI subjects were followed on average for 37 months (m...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2007.06.016

    authors： Hämäläinen A,Tervo S,Grau-Olivares M,Niskanen E,Pennanen C,Huuskonen J,Kivipelto M,Hänninen T,Tapiola M,Vanhanen M,Hallikainen M,Helkala EL,Nissinen A,Vanninen R,Soininen H

    更新日期：2007-10-01 00:00:00

  • Decoding the direction of auditory motion in blind humans.

    abstract：:Accurate processing of nonvisual stimuli is fundamental to humans with visual impairments. In this population, moving sounds activate an occipito-temporal region thought to encompass the equivalent of monkey area MT+, but it remains unclear whether the signal carries information beyond the mere presence of motion. To ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.04.266

    authors： Wolbers T,Zahorik P,Giudice NA

    更新日期：2011-05-15 00:00:00

  • Orbitofrontal reward sensitivity and impulsivity in adult attention deficit hyperactivity disorder.

    abstract：:Impulsivity symptoms of adult attention deficit hyperactivity disorder (ADHD) such as increased risk taking have been linked with impaired reward processing. Previous studies have focused on reward anticipation or on rewarded executive functioning tasks and have described a striatal hyporesponsiveness and orbitofronta...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2011.12.011

    authors： Wilbertz G,van Elst LT,Delgado MR,Maier S,Feige B,Philipsen A,Blechert J

    更新日期：2012-03-01 00:00:00

  • Reduced visual processing capacity in sleep deprived persons.

    abstract：:Multiple experiments have found sleep deprivation to lower task-related parietal and extrastriate visual activation, suggesting a reduction of visual processing capacity in this state. The perceptual load theory of attention (Lavie, 1995) predicts that our capacity to process unattended distractors will be reduced by ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.12.057

    authors： Kong D,Soon CS,Chee MW

    更新日期：2011-03-15 00:00:00

  • Double dissociation between action-driven and perception-driven conflict resolution invoking anterior versus posterior brain systems.

    abstract：:The ability to select and integrate relevant information in the presence of competing irrelevant information can be enhanced by advance information to direct attention and guide response selection. Attentional preparation can reduce perceptual and response conflict, yet little is known about the neural source of confl...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.06.058

    authors： Schulte T,Müller-Oehring EM,Vinco S,Hoeft F,Pfefferbaum A,Sullivan EV

    更新日期：2009-11-01 00:00:00