Abstract:
:Animal testing is crucial in situations when research on humans is not allowed because of unknown health risks and ethical concerns. The current project aims to develop reporting guidelines exclusively for animal studies in Endodontology, using an established consensus-based methodology. The guidelines have been named: Preferred Reporting Items for Animal Studies in Endodontology (PRIASE) 2021. Nine individuals (PD, VN, AK, PM, MN, JF, EP, JJ and SJ), including the project leaders (PD, VN) formed a steering committee. The steering committee developed a novel checklist by adapting and integrating their animal testing and peer review experience with the Animals in Research: Reporting In Vivo Experiments (ARRIVE) guidelines and also the Clinical and Laboratory Images in Publications (CLIP) principles. A PRIASE Delphi Group (PDG) and PRIASE Online Meeting Group (POMG) were also formed. Thirty-one PDG members participated in the online Delphi process and achieved consensus on the checklist items and flowchart that were used to formulate the PRIASE guidelines. The novel PRIASE 2021 guidelines were discussed with the POMG on 9 September 2020 via a Zoom online video call attended by 21 individuals from across the globe and seven steering committee members. Following the discussions, the guidelines were modified and then piloted by several authors whilst writing a manuscript involving research on animals. The PRIASE 2021 guidelines are a checklist consisting of 11 domains and 43 individual items together with a flowchart. The PRIASE 2021 guidelines are focused on improving the methodological principles, reproducibility and quality of animal studies in order to enhance their reliability as well as repeatability to estimate the effects of endodontic treatments and usefulness for guiding future clinical studies on humans.
journal_name
Int Endod Jjournal_title
International endodontic journalauthors
Nagendrababu V,Kishen A,Murray PE,Nekoofar MH,de Figueiredo J,Priya E,Jayaraman J,Pulikkotil SJ,Camilleri J,Rm S,Dummer Pdoi
10.1111/iej.13477subject
Has Abstractpub_date
2021-01-15 00:00:00eissn
0143-2885issn
1365-2591pub_type
杂志文章,评审abstract::Rectified turpentine oil can be used to soften or dissolve gutta-percha in the root canal space to facilitate endodontic retreatment or preparation of space for a post. For endodontic retreatment, the turpentine oil can be heated to 71 degrees C which significantly increases its ability to dissolve gutta-percha. For r...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.1996.tb01167.x
更新日期:1996-03-01 00:00:00
abstract::In an effort to simulate the infected dental root canal, bacteria were enclosed in polyethylene tubes that were subcutaneously implanted into rats. Four different bacterial combinations, selected from nine oral species, were tested. The contents of 144 inoculated and implanted 'root canals' were analysed after 2 and 4...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.1989.tb00931.x
更新日期:1989-11-01 00:00:00
abstract:AIMS:To investigate and compare views on management of deep caries and the exposed pulp by Endodontic Society members in Ireland (Irish Endodontic Society [IES]) and Italy (Accademia Italiana di Endodonzia [AIE]). Further aims were to investigate the influence of patient-related factors (age, symptoms) and operator-rel...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.13418
更新日期:2020-09-24 00:00:00
abstract:AIM:To evaluate the effect of irrigation with 5% sodium hypochlorite (NaOCl) alone and in conjunction with 17% ethylenediaminetetraacetic acid (EDTA) on tooth surface strain (TSS) and to analyse the influence of irrigation time, root morphology and dentine thickness. METHODOLOGY:Thirty-six single-rooted pre-molars wit...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2009.01655.x
更新日期:2010-03-01 00:00:00
abstract:AIM:The aim of this study was to determine the shaping ability of Quantec LX nickel-titanium rotary instruments in simulated root canals. METHODOLOGY:Forty simulated canals consisting of four different shapes in terms of angle and position of curvature were prepared with Quantec LX instruments. Sequential still images...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1046/j.1365-2591.2000.00311.x
更新日期:2000-07-01 00:00:00
abstract::Thorough knowledge of anatomical complexities of the root canal system has a direct impact on the effectiveness of canal preparation and filling, and is an essential prerequisite for successful root canal treatment. A wide range of complex variations in root canal anatomy exists, including root canal configuration typ...
journal_title:International endodontic journal
pub_type: 杂志文章,评审
doi:10.1111/iej.12800
更新日期:2018-02-01 00:00:00
abstract:AIM:To compare the push-out bond strength exhibited by root fillings performed with either C-Point and Endosequence® BC sealer™ (BC Sealer) or gutta-percha and AH Plus® after the instrumentation of oval canals with either the Self-Adjusting File (SAF) System or WaveOne (WO) reciprocating file. METHODOLOGY:Eighty extra...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.12455
更新日期:2016-04-01 00:00:00
abstract::The short-term tissue responses to two potential root-end filling materials, a light-cured glass ionomer cement (Vitrebond) and a reinforced zinc oxide-eugenol cement (Kalzinol), were compared with that to amalgam using a previously devised experimental model. In 24 premolar teeth of beagle dogs (47 roots), a collecti...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1046/j.1365-2591.1997.00077.x
更新日期:1997-07-01 00:00:00
abstract:AIM:To identify the suitable ratio of alternative radiopacifiers to impart the necessary radiopacity to calcium silicate cements (CSC) and assess the purity of the radiopacifying agents. METHODOLOGY:Alternative radiopacifying materials for incorporation into CSC included barium sulphate, titanium oxide, zinc oxide, go...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2009.01621.x
更新日期:2010-01-01 00:00:00
abstract::The use of a resin-based glass ionomer as an endodontic sealer was studied in vitro. The root canals of extracted single-rooted human teeth with mature apices were prepared using a stepback technique. Subsequently, the smear layer was removed with 40% citric acid and the canals obturated using lateral condensation of ...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.1992.tb01156.x
更新日期:1992-09-01 00:00:00
abstract::An in-vitro investigation was performed to assess the extent of apical microleakage in simulated canals in clear resin blocks. Four different methods of producing dye penetration were employed: passive dye penetration alone, centrifugation alone, vacuum plus passive dye penetration, and increased pressure plus passive...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.1996.tb01362.x
更新日期:1996-05-01 00:00:00
abstract::The effect of temperature of plasticization on the sealing ability of Thermafil obturators was evaluated. Forty-eight canals in roots of extracted human mandibular molar teeth were divided into four groups of 12. The root canals had curvatures of less than 25 degrees, as determined using the Schneider technique. Four ...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.1994.tb00227.x
更新日期:1994-01-01 00:00:00
abstract:AIM:To compare periapical health using samples from prehistoric and historic periods until the present day, and to emphasize the major risk indicators for apical periodontitis (AP). METHODOLOGY:A comparative survey to assess periapical health was performed on five samples (525 individuals) drawn from different periods...
journal_title:International endodontic journal
pub_type: 历史文章,杂志文章
doi:10.1111/j.1365-2591.2005.00905.x
更新日期:2005-05-01 00:00:00
abstract:AIM:To determine factors that may influence treatment outcome and healing time following root canal treatment. METHODOLOGY:Root filled and restored teeth by pre-doctoral students were included in this study. Teeth/roots were followed-up regularly, and treatment outcome was evaluated at every follow-up appointment (hea...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.12429
更新日期:2016-01-01 00:00:00
abstract:AIM:To report on the use of cone beam computed tomography (CBCT) in the diagnosis and management of dens invaginatus. SUMMARY:Chronic apical periodontitis of an invaginated maxillary lateral incisor was diagnosed in a patient suffering from hypodontia and awaiting active orthodontic therapy. Loss of the tooth would ha...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2011.01866.x
更新日期:2011-05-01 00:00:00
abstract:AIM:To investigate in vitro the cytocompatibility of the calcium silicate-containing endodontic sealers MTA Fillapex and TotalFill BC Sealer on human periodontal ligament stem cells (hPDLSCs) by assaying their biological responses and compare them with that observed when using an epoxy resin-based sealer (AH Plus). ME...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.12596
更新日期:2017-01-01 00:00:00
abstract::During the past few decades several authors have perpetuated the notion that nearly half of all periapical lesions are radicular cysts. A few studies, based on meticulous serial sectioning of periapical lesions retrieved in toto, have shown that the actual incidence of radicular cyst is only about 15% of all periapica...
journal_title:International endodontic journal
pub_type: 杂志文章,评审
doi:10.1046/j.1365-2591.1998.00146.x
更新日期:1998-05-01 00:00:00
abstract:AIM:To present examples of radiographic image reconstructions in endodontic treatment, to discuss the potential problems arising from the use of image processing software and to mention some current methods to prevent such counterfeit utilization of digital endodontic radiographs. SUMMARY:Conventional Ultra-Speed peri...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.0143-2885.2004.00780.x
更新日期:2004-03-01 00:00:00
abstract:AIM:To report on a novel method to instrument a dilacerated double-curved mandibular premolar. SUMMARY:A 45-year-old female was referred suffering from diffuse pain emanating from the mandibular right quadrant. The second premolar (tooth 45) was diagnosed with symptomatic irreversible pulpitis. The radiographic examin...
journal_title:International endodontic journal
pub_type:
doi:10.1111/iej.12610
更新日期:2017-02-01 00:00:00
abstract:AIM:To engineer systems using polyisoprene (PI) or polycaprolactone (PCL) and nanometric bioactive glass 45S5 (BG) that could create a hydroxyapatite interface and thus ultimately make the use of an endodontic sealer unnecessary. METHODOLOGY:Different composites using PI or PCL as matrix material were prepared with BG...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2010.01772.x
更新日期:2010-11-01 00:00:00
abstract:AIM:To report the management of an iatrogenic incident in which an endodontic file was swallowed accidentally and passed into the gastrointestinal tract. SUMMARY:A 51-year-old male swallowed a 21 mm, size 30 endodontic file during root canal treatment without rubber dam. In the absence of clinical complications, the p...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2008.01392.x
更新日期:2008-07-01 00:00:00
abstract:AIM:To determine the bacterial microbiota in root canals associated with persistent apical periodontitis and their relationship with the clinical characteristics of patients using next-generation sequencing (NGS). METHODOLOGY:Bacterial samples from root canals associated with teeth having persistent apical periodontit...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.12953
更新日期:2018-12-01 00:00:00
abstract:AIM:To investigate differences in the root canal morphology of permanent mandibular molar teeth at various ages. METHODOLOGY:Four hundred and eighty permanent mandibular first and second molars were examined. First and second molars were divided into six and five groups, respectively, according to the age of the patie...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2008.01428.x
更新日期:2008-10-01 00:00:00
abstract:AIM:To determine the influence of filling technique and root canal area on the percentage of gutta-percha (PGP) in laterally compacted root fillings. METHODOLOGY:Sixty extracted canine teeth were accessed and the root canals instrumented to the same size. They were then divided in three groups and filled with laterall...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2009.01575.x
更新日期:2009-08-01 00:00:00
abstract:AIM:To evaluate the therapeutic effect of Simvastatin on apical periodontitis in rats by assessing the osteoblast production of receptor activator of nuclear factor-Kappa B Ligand (RANKL) and Osteoprotegerin (OPG) cytokines that are essential for bone resorption. METHODOLOGY:Twenty-five healthy 8- to 10-week-old male ...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.12101
更新日期:2013-11-01 00:00:00
abstract::Irrigation solutions and intracanal medicaments are used within the root canal to clean and aid in disinfecting the dentinal walls. Although these materials are intended to be contained within the root canal, they invariably contact the periapical tissues, either through inadvertent extrusion through the apex or leach...
journal_title:International endodontic journal
pub_type: 杂志文章,评审
doi:10.1046/j.1365-2591.2003.00631.x
更新日期:2003-02-01 00:00:00
abstract:AIM:The purpose was to present the frequency of periapical healing in first and second/third mandibular molars, after root-end resections sealed with a dentine-bonded resin composite. METHODOLOGY:Root-end sealing of resected mandibular molar roots was made with dentine-bonded composite (Gluma-Retroplast) as a cover on...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1046/j.1365-2591.2001.00383.x
更新日期:2001-06-01 00:00:00
abstract::This study was conducted to evaluate the efficacy of the antibacterial activity of Ca(OH)2 and a sustained-release device containing chlorhexidine (SRD) in both sterilization and prevention of secondary infection of the root canal system. Bovine root dentine specimens previously incubated with Streptococcus faecalis w...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.1992.tb00944.x
更新日期:1992-01-01 00:00:00
abstract:AIM:To describe the successful non-surgical endodontic management of a permanent maxillary lateral incisor tooth with four root canals. SUMMARY:Aberrant morphology of root canals can occur in any tooth, including maxillary lateral incisors. In the presented case, clinical examination and radiographs clearly depicted t...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2011.01984.x
更新日期:2012-04-01 00:00:00
abstract:AIM:To report the use of cone beam computed tomography in the assessment of external cervical resorption lesions. SUMMARY:Asymptomatic external cervical resorption lesions were diagnosed radiographically in two patients. Clinical examination in both cases was unremarkable. Cone beam computed tomography scans revealed ...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2007.01247.x
更新日期:2007-09-01 00:00:00