A comparison of the efficacy and safety of traditional Chinese medicine external treatment for the knee osteoarthritis: A protocol for systematic review and network meta-analysis.

Abstract:

BACKGROUND:Knee osteoarthritis (KOA), also known as degenerative osteoarthritis, is a common and frequently occurring disease in orthopedics with cartilage degeneration as the pathogenic cause and articular bone hyperplasia as the sign. Many studies have confirmed that KOA can be effectively treated by traditional Chinese medicine (TCM) external treatment. So we take advantage of the method of network meta-analysis to systematically compare the efficacy and safety of different types of TCM external treatment for the KOA. METHODS:We will research on external treatment of KOA by traditional Chinese medicine using randomized controlled trials (RCTs) in search database (EMBASE, PubMed, Web of Science, Chinese National Knowledge Infrastructure [CNKI], Weipu database [VIP], Wanfang, and China BioMedical Literature [CBM]). The data and evidence obtained will be processed using Stata 15.0 and WinBUGS 1.4.3. RESULTS:We will evaluate the efficacy and safety of traditional Chinese medicine external treatment for the knee osteoarthritis in this study. CONCLUSION:This study will provide a new regimen for KOA treatment. It has extremely high reference value. INPLASY REGISTRATION NUMBER:INPLASY2020120001. DOI NUMBER:: 10.37766/inplasy2020.12.0001.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Song X,Wang Z,Zhang P,Zhao M,Yang L,Zhang W

doi

10.1097/MD.0000000000024115

subject

Has Abstract

pub_date

2021-01-08 00:00:00

pages

e24115

issue

1

eissn

0025-7974

issn

1536-5964

pii

00005792-202101080-00056

journal_volume

100

pub_type

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