Abstract:
:The inaugural "Microbiome for Mars" virtual workshop took place on July 13, 2020. This event assembled leaders in microbiome research and development to discuss their work and how it may relate to long-duration human space travel. The conference focused on surveying current microbiome research, future endeavors, and how this growing field could broadly impact human health and space exploration. This report summarizes each speaker's presentation in the order presented at the workshop.
journal_name
Microbiomejournal_title
Microbiomeauthors
LaPelusa M,Donoviel D,Branzini SE,Carlson PE Jr,Culler S,Cheema AK,Kaddurah-Daouk R,Kelly D,de Cremoux I,Knight R,Krajmalnik-Brown R,Mayo SL,Mazmanian SK,Mayer EA,Petrosino JF,Garrison Kdoi
10.1186/s40168-020-00951-5subject
Has Abstractpub_date
2021-01-04 00:00:00pages
2issue
1issn
2049-2618pii
10.1186/s40168-020-00951-5journal_volume
9pub_type
杂志文章相关文献
Microbiome文献大全abstract:BACKGROUND:Microorganisms have long been associated with oxic and anoxic degradation of hydrocarbons in oil reservoirs and oil production facilities. While we can readily determine the abundance of microorganisms in the reservoir and study their activity in the laboratory, it has been challenging to resolve what microb...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-017-0392-1
更新日期:2018-01-05 00:00:00
abstract:BACKGROUND:Bacterial vaginosis (BV), the most common vaginal condition of reproductive-aged women, is associated with a highly diverse and heterogeneous microbiota. Here we present a proof-of-principle analysis to uncover the function of the microbiota using meta-RNA-seq to uncover genes and pathways that potentially d...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/2049-2618-1-12
更新日期:2013-04-12 00:00:00
abstract:BACKGROUND:Taxonomic profiles of vaginal microbial communities can be sorted into a discrete number of categories termed community state types (CSTs). This approach is advantageous because collapsing a hyper-dimensional taxonomic profile into a single categorical variable enables efforts such as data exploration, epide...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-020-00934-6
更新日期:2020-11-23 00:00:00
abstract::Following publication of the original article [1], the authors reported an error in Figure 1 and a text on page 13. In Figure 1, some areas are missing and the correct figure is presented here. On page 13, the sentence should be updated to the following (change has been indicated in bold italics). ...
journal_title:Microbiome
pub_type: 已发布勘误
doi:10.1186/s40168-019-0763-x
更新日期:2019-11-14 00:00:00
abstract:BACKGROUND:Periodontitis is an infectious and inflammatory disease of polymicrobial etiology that can lead to the destruction of bones and tissues that support the teeth. The management of chronic periodontitis (CP) relies heavily on elimination or at least control of known pathogenic consortia associated with the dise...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/2049-2618-2-32
更新日期:2014-08-26 00:00:00
abstract:BACKGROUND:Sub-therapeutic antibiotics are widely used as growth promoters in the poultry industry; however, the resulting antibiotic resistance threatens public health. A plant-derived growth promoter, Macleaya cordata extract (MCE), with effective ingredients of benzylisoquinoline alkaloids, is a potential alternativ...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-018-0590-5
更新日期:2018-11-27 00:00:00
abstract:BACKGROUND:Dental plaque is composed of hundreds of bacterial taxonomic units and represents one of the most diverse and stable microbial ecosystems associated with the human body. Taxonomic composition and functional capacity of mature plaque is gradually shaped during several stages of community assembly via processe...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-018-0591-4
更新日期:2018-12-06 00:00:00
abstract:BACKGROUND:The human gut microbiome performs important functions in human health and disease. A classic example for host-gut microbial co-metabolism is host biosynthesis of primary bile acids and their subsequent deconjugation and transformation by the gut microbiome. To understand these system-level host-microbe inter...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-019-0689-3
更新日期:2019-05-15 00:00:00
abstract:BACKGROUND:This proof-of-principle study examines whether postnatal, low-dose exposure to environmental chemicals modifies the composition of gut microbiome. Three chemicals that are widely used in personal care products-diethyl phthalate (DEP), methylparaben (MPB), triclosan (TCS)-and their mixture (MIX) were administ...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-016-0173-2
更新日期:2016-06-14 00:00:00
abstract:BACKGROUND:The interplay between hosts and their associated microbiome is now recognized as a fundamental basis of the ecology, evolution, and development of both players. These interdependencies inspired a new view of multicellular organisms as "metaorganisms." The goal of the Collaborative Research Center "Origin and...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-019-0743-1
更新日期:2019-09-14 00:00:00
abstract:BACKGROUND:Otitis media (OM) imposes a great burden of disease in indigenous populations around the world, despite a variety of treatment and prevention programs. Improved understanding of the pathogenesis of OM in indigenous populations is required to advance treatment and reduce prevalence. We conducted a systematic ...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-018-0577-2
更新日期:2018-11-05 00:00:00
abstract:BACKGROUND:The photic zone of aquatic habitats is subjected to strong physicochemical gradients. To analyze the fine-scale variations in the marine microbiome, we collected seven samples from a single offshore location in the Mediterranean at 15 m depth intervals during a period of strong stratification, as well as two...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-018-0513-5
更新日期:2018-07-10 00:00:00
abstract::Chronic inflammation represents one of the most consistent biologic features of aging. However, the precise etiology of persistent low-grade increases in inflammation remains unclear. Recent evidence suggests that the gut microbiome may play a key role in age-related inflammation. Indeed, several studies have indicate...
journal_title:Microbiome
pub_type: 杂志文章,评审
doi:10.1186/s40168-017-0296-0
更新日期:2017-07-14 00:00:00
abstract:BACKGROUND:Clostridium difficile infection (CDI) is the leading infectious cause of nosocomial diarrhea. Hospitalized patients are at increased risk of developing CDI because they are exposed to C. difficile spores through contact with the hospital environment and often receive antibiotics and other medications that ca...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-016-0156-3
更新日期:2016-03-14 00:00:00
abstract:BACKGROUND:In previous studies, the gram-positive firmicute genus Paenibacillus was found with significant abundances in nests of wild solitary bees. Paenibacillus larvae is well-known for beekeepers as a severe pathogen causing the fatal honey bee disease American foulbrood, and other members of the genus are either s...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-018-0614-1
更新日期:2018-12-22 00:00:00
abstract:BACKGROUND:Intestinal microbiota restoration can be achieved by complementing a subject's perturbed microbiota with that of a healthy donor. Recurrent Clostridioides difficile infection (rCDI) is one key application of such treatment. Another emerging application of interest is reducing antibiotic-resistant genes (ARGs...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-020-00907-9
更新日期:2020-08-31 00:00:00
abstract:BACKGROUND:Microorganisms comprise the majority of living organisms on our planet. For many years, exploration of the composition of microbial communities has been performed through the PCR-based study of the small subunit rRNA gene due to its high conservation across the domains of life. The application of this method...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-018-0442-3
更新日期:2018-03-27 00:00:00
abstract:BACKGROUND:The use of culture-independent nucleic acid techniques, such as ribosomal RNA gene cloning library analysis, has unveiled the tremendous microbial diversity that exists in natural environments. In sharp contrast to this great achievement is the current difficulty in cultivating the majority of bacterial spec...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/2049-2618-1-4
更新日期:2013-01-09 00:00:00
abstract:BACKGROUND:Polycyclic aromatic hydrocarbons (PAHs) are of environmental and public health concerns and contribute to adverse skin attributes such as premature skin aging and pigmentary disorder. However, little information is available on the potential roles of chronic urban PAH pollutant exposure on the cutaneous micr...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-020-00874-1
更新日期:2020-06-26 00:00:00
abstract:BACKGROUND:Wastewater treatment plants (WWTPs) are recognized as hotspots for horizontal gene transfer (HGT) of antibiotic resistance genes (ARGs). Despite our understanding of the composition and distribution of ARGs in WWTPs, the genetic location, host, and fate of ARGs remain largely unknown. RESULTS:In this study,...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-019-0663-0
更新日期:2019-03-21 00:00:00
abstract:BACKGROUND:Alterations of gut microbiota are associated with colorectal cancer (CRC) in different populations and several bacterial species were found to contribute to the tumorigenesis. The potential use of gut microbes as markers for early diagnosis has also been reported. However, cohort specific noises may distort ...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-018-0451-2
更新日期:2018-04-11 00:00:00
abstract::Following publication of the original article [1], the authors reported an error in Fig. 2. The original Fig. 2 has been incorrectly replaced with the Supplementary Fig. 2. The correct Fig. 2 is presented here. ...
journal_title:Microbiome
pub_type: 杂志文章,已发布勘误
doi:10.1186/s40168-020-00829-6
更新日期:2020-04-06 00:00:00
abstract:BACKGROUND:Dental calculus, calcified oral plaque biofilm, contains microbial and host biomolecules that can be used to study historic microbiome communities and host responses. Dental calculus does not typically accumulate as much today as historically, and clinical oral microbiome research studies focus primarily on ...
journal_title:Microbiome
pub_type: 历史文章,杂志文章
doi:10.1186/s40168-019-0717-3
更新日期:2019-07-06 00:00:00
abstract:BACKGROUND:The microbial populations of the human intestinal tract and their relationship to specific diseases have been extensively studied during the last decade. However, the characterization of the human bile microbiota as a whole has been hampered by difficulties in accessing biological samples and the lack of ade...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-019-0712-8
更新日期:2019-07-04 00:00:00
abstract:BACKGROUND:The degree to which host genetic variation can modulate microbial communities in humans remains an open question. Here, we performed a genetic mapping study of the microbiome in two accessible upper airway sites, the nasopharynx and the nasal vestibule, during two seasons in 144 adult members of a founder po...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-016-0227-5
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Archaea are one of the least-studied members of the gut-dwelling autochthonous microbiota. Few studies have reported the dominance of methanogens in the archaeal microbiome (archaeome) of the human gut, although limited information regarding the diversity and abundance of other archaeal phylotypes is availab...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-020-00894-x
更新日期:2020-08-04 00:00:00
abstract:BACKGROUND:Gastrointestinal mucosal injury (mucositis), commonly affecting the oral cavity, is a clinically significant yet incompletely understood complication of cancer chemotherapy. Although antineoplastic cytotoxicity constitutes the primary injury trigger, the interaction of oral microbial commensals with mucosal ...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-019-0679-5
更新日期:2019-04-25 00:00:00
abstract:BACKGROUND:Bacterial predation is an important selective force in microbial community structure and dynamics. However, only a limited number of predatory bacteria have been reported, and their predatory strategies and evolutionary adaptations remain elusive. We recently isolated a novel group of bacterial predators, Br...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-020-00902-0
更新日期:2020-08-31 00:00:00
abstract:BACKGROUND:Fecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridium difficile infection and shows promise for treating other medical conditions associated with intestinal dysbioses. However, we lack a sufficient understanding of which microbial populations successfully colonize the rec...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-017-0270-x
更新日期:2017-05-04 00:00:00
abstract:BACKGROUND:High-throughput amplicon sequencing spanning conserved portions of microbial genomes (16s rRNA and ITS) was used in the present study to describe the endophytic microbiota associated with three apple varieties, "Royal Gala," "Golden Delicious," and "Honey Crisp," and two rootstocks, M.9 and M.M.111. The obje...
journal_title:Microbiome
pub_type: 杂志文章
doi:10.1186/s40168-018-0403-x
更新日期:2018-01-27 00:00:00