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Effects of changes in infusion rate versus glucose concentration on absorption in infant miniature pig small intestine.

Abstract：

:The effect of changes in the rate of infusion versus glucose concentration on glucose, water, and sodium absorption was studied in 20 infant miniature pigs using the single-pass small intestinal perfusion technique. During infusions of glucose loads of up to 75.0 mumol/min, glucose absorption increased similarly whether rate of infusion or glucose concentration was increased. Beyond 75.0 mumol/min, glucose absorption was not altered by changes in infusion rate, but was enhanced by increases in glucose concentration (slope of rate vs. concentration, p less than 0.0001). Net water and sodium absorption were similar in the two groups except for a decrease at the highest glucose concentration (rate vs. concentration at 187.5 mumol/min, p less than 0.05). A glucose concentration of 112.5 mM resulted in maximal glucose, water, and sodium absorption.

journal_name

Gastroenterology

journal_title

Gastroenterology

authors

Shulman RJ,Lifschitz CH

doi

10.1016/0016-5085(88)90245-4

subject

Has Abstract

pub_date

1988-03-01 00:00:00

pages

722-5

issue

3

eissn

0016-5085

issn

1528-0012

pii

0016-5085(88)90245-4

journal_volume

94

pub_type

杂志文章

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