Abstract:
RATIONALE AND OBJECTIVES:Diffusion-weighted imaging (DWI) is a noninvasive imaging technique that reflects the diffusion movement of water molecules through apparent diffusion coefficient (ADC) values. The role of DWI in predicting the histological response to neoadjuvant chemotherapy in osteosarcoma is being increasingly researched, and a systematic review and meta-analysis of this topic is urgently required to help determine the potential diagnostic value of DWI. MATERIALS AND METHODS:The present meta-analysis included 13 studies (303 patients). We divided the target population into good responders and poor responders based on tumor necrosis on histological biopsy (≥90%, good responders). The mean ADC values and ADC ratio were extracted and/or calculated for the two groups. RESULTS:The mean difference in ADC values before and after neoadjuvant chemotherapy was significantly higher in good responders than in poor responders (mean difference, 0.33; 95% confidence interval [CI], 0.18-0.49; p< 0.0001), and significant heterogeneity was present among the 10 studies that reported these values (I2 = 66%, p< 0.05). The ADC ratio was also significantly higher in good responders than in poor responders (mean difference, 28.34; 95% CI, 1.83-54.85; p = 0.04), and significant heterogeneity in ADC ratio was present among 7 studies (I2 = 97%, p< 0.05). CONCLUSION:The mean differences in ADC values and ADC ratios before and after neoadjuvant chemotherapy for osteosarcoma were significantly higher in good responders than in poor responders.
journal_name
Acad Radioljournal_title
Academic radiologyauthors
Yuan W,Yu Q,Wang Z,Huang J,Wang J,Long Ldoi
10.1016/j.acra.2020.11.013subject
Has Abstractpub_date
2020-12-29 00:00:00eissn
1076-6332issn
1878-4046pii
S1076-6332(20)30649-8pub_type
杂志文章,评审abstract:RATIONALE AND OBJECTIVES:Pulmonary atelectasis presumably promotes and facilitates lung injury. However, data are limited on its direct and remote relation to inflammation. We aimed to assess regional 2-deoxy-2-[18F]-fluoro-D-glucose (18F-FDG) kinetics representative of inflammation in atelectatic and normally aerated ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2019.12.022
更新日期:2020-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:We investigated the methodologic development of computed microtomography (CMT) for monitoring the development of osteoporosis in male Sprague-Dawley rats. METHODS:Eight rats were gastrectomized and eight rats were sham operated. Femurs, tibias, and tails were prepared, and CMT scans with spati...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(05)80487-8
更新日期:1995-09-01 00:00:00
abstract::Innovation in the field of diagnostic imaging is based primarily on the availability of new and improved equipment that opens the door for new clinical applications. Payments for these imaging procedures are subject to complex Medicare price control schemes, affecting incentives for appropriate use and innovation. Ach...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2011.04.007
更新日期:2011-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The authors compared diagnostic accuracy and callback rates with conventional screen-film mammograms and wavelet-compressed digitized images. MATERIALS AND METHODS:Sixty sets of mammograms (four views per case) were digitized at a spatial resolution of 100 microm. The images were wavelet compr...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(00)80004-5
更新日期:2000-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study explores morphological relationships and structural variability of the corpus callosum (CC), fornix (Fo), anterior (AC), and posterior commissures (PC). MATERIALS AND METHODS:These structures are extracted automatically on the midsagittal plane. The CC and Fo are modeled using best-...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2005.06.018
更新日期:2006-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Scanning parameters used in multislice computed tomographic (MSCT) coronary angiography should be adapted to patients' heart rates. The aim of this study was to evaluate the rate of success of a software-assisted scan simulation to determine optimal gantry rotation time prior to MSCT coronary a...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2008.08.016
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:There is compelling evidence that neurochemical changes measured by proton magnetic resonance spectroscopy (1H-MRS) occur at different phases of Alzheimer's disease (AD). However, the extent to which these neurochemical changes are associated with validated AD biomarkers and/or apolipoprotein (APOE) ε4 is ye...
journal_title:Academic radiology
pub_type: 杂志文章,评审
doi:10.1016/j.acra.2020.06.006
更新日期:2020-07-07 00:00:00
abstract:RATIONALE AND OBJECTIVES:To investigate the relationship between apparent diffusion coefficient (ADC) values and the Ki-67 staining index (Ki-67 SI), a tumor proliferation marker, in prostate cancer (PCa). MATERIALS AND METHODS:Forty-three patients with PCa and thirty-six patients with benign prostatic hyperplasia (BP...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2013.09.007
更新日期:2013-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Diffusion tensor tractography (DTT) for neural fibers of the head-and-neck region at 3T has not been reported. The purpose of this study was to evaluate the feasibility of using DTT for visualizing neural fibers in the head-and-neck region at 3T and to explore the use of this method in patients...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2009.01.019
更新日期:2009-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Renovascular smooth muscle contractility, an important factor in contrast media-induced nephrotoxicity, depends on intracellular Ca2+ concentration, which is composed of extracellular Ca2+ influx and intracellular Ca2+ release. These factors were investigated in contrast media-induced renal vas...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(96)80298-4
更新日期:1996-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Emphysema is a hallmark of chronic obstructive pulmonary disease. The primary aim of this study was to investigate inter- and intraobserver agreement of visual assessment of mild emphysema in low-dose multidetector computed tomography of subjects in the pilot SCAPIS in order to certify consiste...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2019.06.019
更新日期:2020-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Abdominal radiologists actively participated and provided subspecialty radiologic expertise in a multidisciplinary gastrointestinal cancer clinic that served a tertiary referral center. The purpose of this study was to evaluate the feasibility and nonradiologists' opinions of this new approach ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(98)80564-3
更新日期:1998-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To compare the results of two software-based methods, Quantra and Volpara, for volumetric breast composition assessment. MATERIALS AND METHODS:Four hundred forty-five normal, bilateral, two-view, digital mammograms were included. Breast volume (BV), fibroglandular tissue volume (FTV), and perc...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2014.12.003
更新日期:2015-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of the study was to evaluate the impact of the latest coronary computed tomography angiography (CCTA) techniques allowing a radiation- and contrast-sparing protocol on image quality in unselected patients referred for exclusion of suspected coronary artery disease (CAD). MATERIALS AND ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2016.03.015
更新日期:2016-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The American Association of Academic Chief Residents in Radiology annually surveys residency programs on a variety of issues related to residency training. The survey results allow individual programs to compare features of their programs with national averages and to gauge trends in radiology ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(98)80288-2
更新日期:1998-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Sodium and proton magnetic resonance imaging (23Na/1H-MRI) have shown that muscle and skin can store Na+ without water. In chronic renal failure and in heart failure, Na+ mobilization occurs, but is variable depending on age, dialysis vintage, and other features. Na+ storage depots have not bee...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2017.03.012
更新日期:2017-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of this study was to describe a simple bootstrap approach for estimating sensitivity, specificity, and the area under the receiver operating characteristic curve for multisite test outcome data. MATERIALS AND METHODS:The performance of bootstrap estimates was evaluated and compared...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(00)80381-5
更新日期:2000-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to investigate the subjective similarity for pairs of images with various abnormal patterns of diffuse interstitial lung disease on thin-section computed tomography by experienced radiologists to explore a basis for selecting similar images to assist radiologists' inte...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2008.10.016
更新日期:2009-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study aimed to determine the appropriate body mass index (BMI)-dependent noise index (NI) setting in computed tomography pulmonary angiography (CTPA) with automatic tube current modulation with adaptive statistical iterative reconstruction (ASiR). MATERIALS AND METHODS:A total of 480 pati...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2016.07.018
更新日期:2016-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Emerging alternative metrics leverage social media and other online platforms to provide immediate measures of biomedical articles' reach among diverse public audiences. We aimed to compare traditional citation and alternative impact metrics for articles in popular general radiology journals. ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2016.11.019
更新日期:2017-07-01 00:00:00
abstract::Technologic advances have resulted in the expansion of web-based conferencing and education. While historically video-conferencing has been used for didactic educational sessions, we present its novel use in virtual radiology read-outs in the face of the COVID-19 pandemic. Knowledge of key aspects of set-up, implement...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.04.028
更新日期:2020-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study's aims were to depict changes in cartilage quality after surgical intervention using magnetic resonance (MR) examination and in content of glycosaminoglycans chains (GAGs) after two types of surgeries - chondral defect treatment by microfractures and scaffold implantation in combinat...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2020.05.030
更新日期:2020-06-30 00:00:00
abstract:RATIONALE AND OBJECTIVES:No single method is generally accepted for evaluating the accuracy of breast biopsy techniques before their clinical implementation. The purpose of this study was to test a new process for evaluating biopsy techniques by using it in the evaluation of a prototype three-dimensional ultrasound (US...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)80331-8
更新日期:2002-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The addition of digital breast tomosynthesis (DBT) to digital screening mammography (DM) has been shown to decrease recall rates and improve cancer detection rates, but there is a lack of data regarding the impact of DBT on rates of short-term follow-up. We assessed possible changes in performa...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2016.10.001
更新日期:2017-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVE:Abnormal neurodevelopment may play a role in the pathophysiology of schizophrenia. We used deformation-based morphometry to examine voxel-wise age-related changes in patients with schizophrenia compared with healthy brains. MATERIALS AND METHODS:We used a set of skull-stripped brains from an im...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2004.06.009
更新日期:2005-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Extraintestinal abnormalities visible without contrast material on abdominal radiographs are reported less frequently when contrast examinations are performed. Gaze dwell time was used to determine whether this difference is due to failure by observers to scan plain-film regions of contrast stu...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(96)80271-6
更新日期:1996-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:We sought to evaluate the diagnostic performance of an artificial neural network (ANN) and binary logistic regression (BLR) in differentiating malignant from benign thyroid nodules on ultrasonography. MATERIALS AND METHODS:Two experienced radiologists, who were unaware of the histopathological...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2007.12.022
更新日期:2008-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Obscure gastrointestinal bleeding (OGIB) is the bleeding from the gastrointestinal tract without definite source that persists and recurs after a negative endoscopic evaluation. The study aimed to systematically evaluate the diagnostic accuracy of computed tomography enterography on OGIB detect...
journal_title:Academic radiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.acra.2017.09.001
更新日期:2018-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of this study was to evaluate the accuracy of ultrasound (US)-guided fine-needle aspiration (FNA), with radiographic follow-up or surgical excision, in conjunction with on-site cytopathologic support in the management of nonpalpable breast lesions. MATERIALS AND METHODS:The finding...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/S1076-6332(03)80501-9
更新日期:2001-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To prospectively analyze the correlation between parameters of liver perfusion from technetium99m-macroaggregates of albumin (99mTc-MAA) single photon emission computed tomography (SPECT) with those obtained from dynamic CT perfusion in patients with primary or metastatic liver malignancy. MAT...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2011.12.015
更新日期:2012-05-01 00:00:00