Psoriasis in Tigray, Ethiopia: Focusing on available treatments.

abstract：:This article presents a short summary of our current knowledge of cicatricial alopecia disease pathogenesis and the hypothetical disease mechanisms that may be involved in scarring alopecia development. Several forms of scarring alopecia likely involve targeted cytotoxic action against hair follicle cells mediated by ...

journal_title：Dermatologic therapy

authors： McElwee KJ

更新日期：2008-07-01 00:00:00

abstract：:Hand-foot syndrome (HFS) is a specific cutaneous toxicity caused by a variety of antitumor drugs. The most common drugs include capecitabine, pegylated liposomal doxorubicin and fluorouracil (PLD), tyrosine kinase inhibitor. It is a dose-limiting cutaneous toxicity of these drugs. We reported an advanced lung adenocar...

journal_title：Dermatologic therapy

authors： Ren Y,Li T,Du LY,Qiu Y,Wang SB,Lei KJ,Jia YM

更新日期：2020-03-01 00:00:00

abstract：INTRODUCTION:There are an increasing number of biologic drugs in the pipeline for treating hidradenitis suppurativa (HS). Clinical trials for these drugs usually share the same clinical selection criteria. OBJECTIVES:(a) To describe the clinical profile of HS patients receiving first-line biologic treatment in an HS c...

journal_title：Dermatologic therapy

authors： Montero-Vilchez T,Salvador-Rodriguez L,Sanchez-Diaz M,Cuenca-Barrales C,Martinez-Lopez A,Arias-Santiago S,Molina-Leyva A

更新日期：2020-11-01 00:00:00

abstract：:Nail involvement can place a significant burden on patients as a result of functional damage and psychosocial problems, leading to major repercussions on the quality of life. There is strong evidence that nail psoriasis can often be difficult to treat. We report a 69-year-old man with severe onychodystrophy, onycholys...

journal_title：Dermatologic therapy

authors： Galluzzo M,D'Adamio S,Chimenti MS,Teoli M,Bianchi L,Talamonti M

更新日期：2019-05-01 00:00:00

abstract：:Psoriasis is a chronic, systemic inflammatory disease that in the moderate to severe forms may benefit of biologics, namely TNF and IL-12/23 and IL-17 inhibitors. Loss of response, lack of response, or discontinuation due to adverse events represent a concrete therapeutic challenge for dermatologists that have to swit...

journal_title：Dermatologic therapy

authors： Damiani G,Conic RRZ,de Vita V,Costanzo A,Regazzini R,Pigatto PDM,Bragazzi NL,Pacifico A,Malagoli P

更新日期：2019-03-01 00:00:00

abstract：:Pemphigus vulgaris (PV), an autoimmune blistering disease is treated with immunosuppressive medications. As the immunosuppressive effect of rituximab, the first-line therapy of PV, lasts more than 6 months, many concerns have raised due to the ongoing novel coronavirus disease (COVID-19) pandemic. With this background...

journal_title：Dermatologic therapy

authors： Beyzaee AM,Rahmatpour Rokni G,Patil A,Goldust M

更新日期：2020-10-13 00:00:00

abstract：:Topical application of timolol cream is effective and convenient for treating superficial infantile hemangiomas. Intralesional injection of corticosteroids, such as diprospan, is useful for the treatment of superficia infantile hemangiomas without systemic side effects. We conducted a self-controlled study to investig...

journal_title：Dermatologic therapy

authors： Xu P,Yu Q,Huang H,Zhang W,Li W

更新日期：2018-05-01 00:00:00

abstract：:Intralesional methotrexate (il-MTX) has been reported as a useful therapy in keratoacanthoma (KA) and cutaneous squamous cell carcinoma (cSCC). However, the data available on the histological changes induced by this therapy are very scarce. We conducted a single center, prospective study that included 65 cases of cSCC...

journal_title：Dermatologic therapy

authors： Bergón-Sendín M,Parra-Blanco V,Pulido-Pérez A,Nieto-Benito LM,Rosell-Díaz ÁM,Suárez-Fernández R

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To explore the inhibition of the proliferation of vulvar squamous cell carcinoma (VSCC) by astragaloside IV. METHODS:MTT examined the cell proliferation of VSCC. Flow cytometry analyzed cell cycle and apoptosis. Western blot assay detected the expression of some relevant proteins. RESULTS:AS-IV reduced the ...

journal_title：Dermatologic therapy

authors： Zhao Y,Wang L,Wang Y,Dong S,Yang S,Guan Y,Wu X

更新日期：2019-07-01 00:00:00

abstract：:We report a case of Alternaria alternata cutaneous and pulmonary infection in a 62-year-old man after heart transplantation treated by azole antifungals. Alternaria spp. belong to a group of opportunistic dematiaceous fungi with worldwide distribution. The cutaneous form of the infection in human is very rare and occu...

journal_title：Dermatologic therapy

authors： Sečníková Z,Jůzlová K,Vojáčková N,Kazakov DV,Hošková L,Fialová J,Džambová M,Hercogová J

更新日期：2014-05-01 00:00:00

abstract：:Tinea pedis affects the life quality distinctly and patients those with a prolonged disease often resort to non-medical methods. We sought to evaluate patients' knowledge about tinea pedis and approaches to the non-pharmacological agents. A cross-sectional study was conducted on 152 patients with tinea pedis who answe...

journal_title：Dermatologic therapy

authors： Kara Polat A,Akın Belli A,Göre Karaali M,Koku Aksu AE

更新日期：2020-11-01 00:00:00

abstract：:Skin cancers are the most common type of cancer. Nonmelanoma skin cancers (NMSCs) are more common than melanoma. Although the mortality rate is low, cancer word can be frightening for patients. Surgery is the main treatment. As skin cancers are most commonly located on the face, undesirable cosmetic results can occur ...

journal_title：Dermatologic therapy

authors： Çetinarslan T,Evrenos MK,Bilaç C,Özyurt B,Türel Ermertcan A

更新日期：2020-11-01 00:00:00

abstract：:Acitretin has been used off-label for years to treat chronic hand eczema, but acitretin is less often prescribed as alitretinoïne was approved. This study evaluates both retinoids in a daily practice cohort of patients with severe chronic hand eczema in terms of drug survival and reasons for discontinuation. Patients ...

journal_title：Dermatologic therapy

authors： Politiek K,Christoffers WA,Coenraads PJ,Schuttelaar MA

更新日期：2016-09-01 00:00:00

abstract：:The recent EAACI/GA2 LEN/EDF/WAO guidelines recommend omalizumab (anti-IgE) for the management of patients aged ≥12 years with chronic urticaria unresponsive to high-doses second-generation H1 -antihistamines (antiH1 ). However, there is little published information on the success of omalizumab for such a treatment in...

journal_title：Dermatologic therapy

authors： Passanisi S,Arasi S,Caminiti L,Crisafulli G,Salzano G,Pajno GB

更新日期：2020-07-01 00:00:00

abstract：:The objective of our study was to describe the effectiveness and safety of oral dutasteride (OD) for male androgenetic alopecia in real clinical practice. A retrospective, monocentric, and descriptive study was designed. Male patients with androgenetic alopecia that had received OD for at least 12 months were included...

journal_title：Dermatologic therapy

authors： Vañó-Galván S,Saceda-Corralo D,Moreno-Arrones OM,Rodrigues-Barata R,Morales C,Gil-Redondo R,Bernárdez-Guerra C,Hermosa-Gelbard Á,Jaén-Olasolo P

更新日期：2020-01-01 00:00:00

abstract：:Malignant melanoma accounts for 80% of deaths due to skin cancer. Its incidence is globally increasing. However, melanoma mortality seems to be decreasing. The aim of this study was to analyze mortality rates due to melanoma in Andalusia between 1979 and 2018. Deaths due to melanoma and mid-year population in Andalusi...

journal_title：Dermatologic therapy

authors： Ortiz-Álvarez J,Durán-Romero AJ,Hernández-Rodríguez JC,Sendín-Martin M,Conejo-Mir J,Pereyra-Rodriguez JJ

更新日期：2020-12-26 00:00:00

abstract：:Neutrophilic folliculitis is an often overlooked chronic condition characterized by a monomorphic eruption of "sterile" papulopustules. Neutrophilic folliculitis is often refractory to conventional treatment with topical and systemic antibiotics or isotretinoin. We report a case of severe pustular neutrophilic follicu...

journal_title：Dermatologic therapy

authors： Sand FL,Thomsen SF

更新日期：2015-03-01 00:00:00

abstract：:It is not common for dermatologists to use intravenous antibiotics in daily practice. However, there are several serious infections that may come to the attention of a dermatologist because of cutaneous signs and symptoms. It is important for dermatologists to be familiar with the presenting symptoms, various stages o...

journal_title：Dermatologic therapy

authors： Sambrano B,Gordon R,Mays R,Lapolla W,Scheinfeld N

更新日期：2012-01-01 00:00:00

abstract：:In the past decade, the expanded use of targeted anticancer drugs has significantly prolonged survival in patients treated for a variety of cancers. Despite their increased specificity, agents such as epidermal growth factor receptor inhibitors (EGFRIs), BRAF inhibitors, and targeted immunotherapies have commonly been...

journal_title：Dermatologic therapy

authors： Fischer A,Rosen AC,Ensslin CJ,Wu S,Lacouture ME

更新日期：2013-03-01 00:00:00

abstract：:The world is facing a viral pandemic of a new coronavirus called COVID-19. Pentoxifylline is a methyl-xanthine derivative and it inhibits the phosphodiesterase IV (PDE IV). This drug is known for its unique features as an immunomodulatory and anti-inflammatory agent, also it could have antiviral affects. This is a sco...

journal_title：Dermatologic therapy

authors： Seirafianpour F,Mozafarpoor S,Fattahi N,Sadeghzadeh-Bazargan A,Hanifiha M,Goodarzi A

更新日期：2020-07-01 00:00:00

abstract：:Tumor necrosis-alpha (TNF-alpha) has been implicated in many forms of inflammation and is an end-stage product of the inflammatory cytokine cascade. It is an inducer of inflammation and is involved in many cutaneous and systemic inflammatory diseases. The development of agents that block the effects of TNF-alpha has a...

journal_title：Dermatologic therapy

authors： Jackson JM

更新日期：2007-07-01 00:00:00

abstract：:The efficacy and safety of efalizumab in the treatment of moderate-to-severe chronic psoriasis has been established in studies of up to 3 years' duration. This study aims to describe the efficacy of up to 15 months' treatment with efalizumab and the convenience of therapy in patients with moderate-to-severe chronic pl...

journal_title：Dermatologic therapy

authors： Toth DP,Papp K,Gratton D

更新日期：2008-11-01 00:00:00

abstract：:This is the first report of a case of porocarcinoma that was successfully treated with maxacalcitol and imiquimod. ...

journal_title：Dermatologic therapy

authors： Nagasawa T,Hirata A,Niiyama S,Enomoto Y,Fukuda H

更新日期：2019-03-01 00:00:00

abstract：:There are many developmental abnormalities that may appear in the neonate and in infants when critical steps in embryogenesis fail. These steps are often not fatal but can lead to significant morbidity for those patients affected. A logical approach is needed in addressing both the diagnostic and therapeutic issues th...

journal_title：Dermatologic therapy

authors： Farvolden D,Sweeney SM,Wiss K

更新日期：2005-03-01 00:00:00

abstract：:Prayer marks are asymptomatic callosities resulting from repeated, extended pressure, and friction exerted on bony prominences when praying on hard ground. A 41-year-old woman with ulcerative colitis treated with infliximab was referred to our clinic due to skin changes on her feet that were suspected to be drug erupt...

journal_title：Dermatologic therapy

authors： Fosse N,Rast AC,Kammermann A,Sonderegger J,Navarini A,Goldust M,Brandt O,Mueller SM

更新日期：2020-01-01 00:00:00

abstract：:Acrodermatitis continua of Hallopeau (ACH) is a rare pustular psoriasis variant refractory to many conventional treatments. We report the successful treatment with secukinumab of a patient with a long history of ACH with marked onychodystrophy with frank pustulosis on the nail bed and with accompanying arthritis. Bloc...

journal_title：Dermatologic therapy

authors： Galluzzo M,D'Adamio S,Teoli M,Bianchi L,Talamonti M

更新日期：2019-05-01 00:00:00

abstract：:Psoriasis is an inflammatory, immune-mediated cutaneous disorder that has recently been recognized as systemic disease that is associated with multiple comorbidities such as depression, obesity, and the metabolic syndrome. The metabolic syndrome is the constellation of abdominal obesity, dyslipidemia, hypertension and...

journal_title：Dermatologic therapy

authors： Alsufyani MA,Golant AK,Lebwohl M

更新日期：2010-03-01 00:00:00

abstract：:Objective of this open, noninterventional, noncontrolled study was to investigate the tolerability and performance of a woad extract containing cream in subjects with dry, pruritic skin after twice daily application over 2 weeks. Assessments included sensorial characteristics, skin condition, pruritus (numeric rating ...

journal_title：Dermatologic therapy

authors： Forner C,Zeidler C,Stein P,Stössel E,Wefelmeier L,Peukert N,Isermann D,Ständer S

更新日期：2019-07-01 00:00:00

abstract：:Cyclosporine A (CYA) belongs to calcineurin inhibitor family, which has the ability to selectively suppress T cells. Owing to its immune-modulatory effects, it had been in use for graft vs host diseases and organ transplant rejection for many years, but in dermatology, it was first approved for use in 1997 in the trea...

journal_title：Dermatologic therapy

authors： Amber T,Tabassum S

更新日期：2020-11-01 00:00:00

abstract：:Lupus miliaris disseminates faciei (LMDF) is a rare inflammatory dermatosis characterized by an asymptomatic papular eruption in the central face, of which the etiology and pathogenesis are not clear. There is a lack of standard treatment recommendations, especially for severe cases. Here we report a new case of succe...

journal_title：Dermatologic therapy

authors： Yin S,Sun L

更新日期：2020-03-01 00:00:00