Abstract:
Introduction:Defecation is a complex process that is difficult to study and analyze. Objectives:Here, we present new analytical tools to calculate frictional force and tension during expulsion of the Fecobionics simulated stool in human subjects. Methods:The 12-cm-long Fecobionics device contained pressure sensors, motion processor units for measurement of orientation and bending, and impedance rings for measurement of cross-sectional areas. Eight normal subjects defecated Fecobionics. The bending angle of the device, frictional force between the device and the surrounding tissue, and the stretch tensions were calculated. Results:The bending angle and pressures changed during expulsion with the maximum pressure recorded at the rear. The averaged circumferential tension, longitudinal tension and friction force in each subject were associated with the front-rear pressure difference (r > 0.7, p < 0.005). The peak circumferential tension, longitudinal tension, and friction force immediately before expulsion of the rear were significantly higher compared to when the front entered the anal canal (F = 164.7, p < 0.005; F = 152.1, p < 0.005; F = 71.4, p < 0.005; respectively.). Conclusion:This study shows that Fecobionics obtained reliable data under physiological conditions. Mechanical features such as frictional force and stretch tensions were assessable during Fecobionics expulsion.
journal_name
J Adv Resjournal_title
Journal of advanced researchauthors
Sun D,Liao D,Chen SC,Wong C,Wah Leung W,Futaba K,Mak T,Ng S,Gregersen Hdoi
10.1016/j.jare.2020.07.002subject
Has Abstractpub_date
2020-07-11 00:00:00pages
245-254eissn
2090-1232issn
2090-1224pii
S2090-1232(20)30161-2journal_volume
28pub_type
杂志文章abstract::The present study aimed to develop the predictive models of average tool-workpiece interface temperature in hard turning of AISI 1060 steels by coated carbide insert. The Response Surface Methodology (RSM) and Artificial Neural Network (ANN) were employed to predict the temperature in respect of cutting speed, feed ra...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2016.05.004
更新日期:2016-11-01 00:00:00
abstract::This work aimed to evaluate the analgesic efficacy of intra-articular injection of magnesium sulphate (4%) compared with equivalent volume of bupivacaine (0.5%) after outpatient knee arthroscopic meniscectomy. Forty patients were randomly assigned to two groups. Group M (n = 20) received intra-articular magnesium sulp...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2012.07.001
更新日期:2013-07-01 00:00:00
abstract::The freshwater Testudine species have gained importance in recent years, as most of their population is threatened due to exploitation for delicacy and pet trade. In this regard, Lissemys punctata, a freshwater terrapin, predominantly distributed in Asian countries has gained its significance for the study. A pilot st...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2017.10.007
更新日期:2017-11-21 00:00:00
abstract::This review covers a summary of the literature data published on the chemistry of bis-hydrazonoyl halides over the last four decades. The biological activities of some of the bis-heterocyclic compounds obtained from these bis-hydrazonoyl halides are also reviewed and discussed. ...
journal_title:Journal of advanced research
pub_type: 杂志文章,评审
doi:10.1016/j.jare.2016.09.001
更新日期:2016-11-01 00:00:00
abstract::Breast cancer (BC) incidence is progressively increasing in Egypt. However, there is insufficient knowledge of the acquired somatic mutations in Egyptian BC patients which limit our understanding of its progression. To the best of our knowledge, this is the first Egyptian cohort to sequence a multiple-gene panel of ca...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2020.04.001
更新日期:2020-04-03 00:00:00
abstract::In this paper, we studied the progression of shallow water waves relevant to the variable coefficient Korteweg-de Vries (vcKdV) equation. We investigated two kinds of cases: when the dispersion and nonlinearity coefficients are proportional, and when they are not linearly dependent. In the first case, it was shown tha...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2014.02.004
更新日期:2015-07-01 00:00:00
abstract::Inflammatory breast cancer (IBC) is a highly metastatic and fatal form of breast cancer. In fact, IBC is characterized by specific morphological, phenotypic, and biological properties that distinguish it from non-IBC. The aggressive behavior of IBC being more common among young women and the low survival rate alarmed ...
journal_title:Journal of advanced research
pub_type: 杂志文章,评审
doi:10.1016/j.jare.2013.06.004
更新日期:2014-09-01 00:00:00
abstract::The optimization of a novel programmable data-flow crypto processor dedicated to security applications is considered. An architecture based on assigning basic functional units to four synchronous regions was proposed in a previous work. In this paper, the problem of selecting the number of synchronous regions and the ...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2017.11.002
更新日期:2017-11-04 00:00:00
abstract::We describe the case of a patient with prostate cancer, ascites, omental and bone metastases, an extremely rare clinical variant that warrants further investigation, and review the relevant literature. ...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2014.05.002
更新日期:2015-05-01 00:00:00
abstract::The isotope effects of neodymium in Nd-glycolate ligand exchange system were studied by using ion exchange chromatography. The separation coefficients of neodymium isotopes, ε's, were calculated from the observed isotopic ratios at the front and rear boundaries of the neodymium adsorption band. The values of separatio...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2012.03.003
更新日期:2013-03-01 00:00:00
abstract::LncRNA (Long non-coding RNA) ZFAS1 (zinc finger antisense 1) functions as the oncogene in multiple cancers, including gastric cancer. However, its function and underlying mechanism in the GCA (gastric cardia adenocarcinoma), the most aggressive type of gastric cancer, remain unknown. We demonstrated here that the LncR...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2020.06.006
更新日期:2020-06-24 00:00:00
abstract::This paper studies the active damping of the oscillations of lightly damped linear systems whose parameters are indeterminate or may change through time. Systems with an arbitrary number of vibration modes are considered. Systems described by partial differential equations, that yield an infinite number of vibration m...
journal_title:Journal of advanced research
pub_type: 杂志文章,评审
doi:10.1016/j.jare.2020.06.008
更新日期:2020-06-20 00:00:00
abstract::Limited progress has been made in the quest to identify both selective and non-toxic T-type calcium channel blocking compounds. The present research work was directed toward slaking the same by identifying the selective three dimensional (3D) pharmacophore map for T-type calcium channel blockers (CCBs). Using HipHop m...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2016.09.004
更新日期:2016-11-01 00:00:00
abstract::The present study investigates the entrapment of terbinafine hydrochloride (TH) in ethosomal vesicles via unsonicated and sonication method. Carbopol 934P was incorporated in the best formulation, F6, obtained by sonication method. The formulated ethosomal gel obtained as such i.e. F6(∗) was exploited to achieve a zer...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2016.03.003
更新日期:2016-05-01 00:00:00
abstract::Alpha-Synuclein (aSyn) is a chameleon-like protein. Its overexpression and intracellular deposition defines neurodegenerative α-synucleinopathies including Parkinson's disease. Whether aSyn up-regulation is the cause or the protective reaction to α-synucleinopathies remains unresolved. Remarkably, the accumulation of ...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2020.01.009
更新日期:2020-01-22 00:00:00
abstract::A combination of gel-casting and polymeric foam infiltration methods is used in this study to prepare porous bodies of hydroxyapatite (HA), to provide a better control over the microstructures of samples. These scaffolds were prepared by impregnating a body of porous polyurethane foam with slurry containing HA powder,...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2015.06.006
更新日期:2016-03-01 00:00:00
abstract::Genetic disorders have been shown to co-occur in individual patient. A Thai boy with features of osteogenesis imperfecta (OI) and combined pituitary hormone deficiency (CPHD) was identified. The causative mutations were investigated by whole exome and Sanger sequencing. Pathogenicity and pathomechanism of the variants...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2019.10.006
更新日期:2019-10-21 00:00:00
abstract::The study question was whether the use of high-viscosity glass-ionomer with chlorhexidine (HVGIC/CHX) for the Atraumatic Restorative Treatment (ART) prepared cavities could achieve a higher restoration survival percentage and be more effective for preventing dentine carious lesions adjacent to the restoration than the...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2019.01.015
更新日期:2019-01-31 00:00:00
abstract::Adenosine is implicated in the modulation of cardiovascular responses either at the peripheral or at central level in experimental animals. However, there are no dedicated reviews on the involvement of adenosine in mediating the hypotensive response of centrally administered clonidine in general and specifically in ao...
journal_title:Journal of advanced research
pub_type: 杂志文章,评审
doi:10.1016/j.jare.2014.12.005
更新日期:2015-05-01 00:00:00
abstract::This paper reveals and analyzes the frequency bifurcation phenomena in the fractional-order inductive power transfer (FOIPT) system with series-series compensation topology. Using fractional calculus theory and electric circuit theory, the circuit model of the series-series compensated FOIPT system is first proposed, ...
journal_title:Journal of advanced research
pub_type: 杂志文章,评审
doi:10.1016/j.jare.2020.04.010
更新日期:2020-04-24 00:00:00
abstract::The aim of this work is to present numerical treatments to a complex order fractional nonlinear one-dimensional problem of Burgers' equations. A new parameter σ ...
journal_title:Journal of advanced research
pub_type: 杂志文章,评审
doi:10.1016/j.jare.2020.04.007
更新日期:2020-05-15 00:00:00
abstract::The clinical manifestations of schistosomiasis pass by acute, sub acute and chronic stages that mirror the immune response to infection. The later includes in succession innate, TH1 and TH2 adaptive stages, with an ultimate establishment of concomitant immunity. Some patients may also develop late complications, or su...
journal_title:Journal of advanced research
pub_type: 杂志文章,评审
doi:10.1016/j.jare.2013.01.005
更新日期:2013-09-01 00:00:00
abstract::Clinical assessment of functional disability is an integral part of management in patients with low back pain (LBP). The range of spinal motion is one of LBP disability measure. The aim of this study was to investigate the validity of spinal range of motion as a predictable measure of disability and to analyze the int...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2012.01.002
更新日期:2013-01-01 00:00:00
abstract::Peyronie's disease is characterized by fibrous plaque formation of the tunica albuginea, causing penile deformity and fertility problems. The aim of the present study was to investigate alterations in the extracellular matrix in Peyronie's disease. The study used tissues collected by surgical procedure from individual...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2017.06.004
更新日期:2017-07-01 00:00:00
abstract::This study was carried out to investigate the prevalence and monthly intensity of Rhinoestrus (R) spp. among donkeys slaughtered at Giza Zoo abattoir, Egypt. A total of 144 donkeys were examined at postmortem through two visits per month from January 2010 to December 2010. All donkeys were infested with one or more la...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2014.12.003
更新日期:2015-11-01 00:00:00
abstract::Aluminum (Al) is an element widely distributed in soils, even though Al3+ is one of the most detrimental cations to plant growth. The effect of nitric oxide (NO) precursors on indole-3-acetic acid (IAA) flow towards roots upon Al treatment is herein reported using two Triticum aestivum (wheat) cultivars with recognize...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2018.08.002
更新日期:2018-08-30 00:00:00
abstract::Transplanted neural stem cells promote neural tissue regeneration and functional recovery primarily by releasing paracrine factors. Exosomes act as important secreted paracrine molecules to deliver therapeutic agents involved in cellular functions. Here, we focused on the role of exosomes (hNSC-Exo) derived from human...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2020.05.017
更新日期:2020-05-25 00:00:00
abstract::The paper presents an analysis of roadway factors and posted speed limits that affect the operating speed at multi-lane highways in Egypt. Field data on multi-lane highways in Egypt are used in this investigation. The analysis considers two categories of highways. The first consists of two desert roads (Cairo-Alexandr...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2012.08.014
更新日期:2013-11-01 00:00:00
abstract::Inflammation and oxidative stress are two faces of one coin in end stage renal disease patients (ESRD) on maintenance hemodialysis. Their interconnection induces anemia complicated with erythropoietin hyporesponsiveness. The biochemical bases behind the resistance to erythropoietin therapy with frequent hemoglobinemia...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2016.02.004
更新日期:2016-05-01 00:00:00
abstract::This paper presents a fast and simple method for human action recognition. The proposed technique relies on detecting interest points using SIFT (scale invariant feature transform) from each frame of the video. A fine-tuning step is used here to limit the number of interesting points according to the amount of details...
journal_title:Journal of advanced research
pub_type: 杂志文章
doi:10.1016/j.jare.2013.11.007
更新日期:2015-03-01 00:00:00