Correction: Mutant prion proteins increase calcium permeability of AMPA receptors, exacerbating excitotoxicity.

Abstract:

:[This corrects the article DOI: 10.1371/journal.ppat.1008654.].

journal_name

PLoS Pathog

journal_title

PLoS pathogens

authors

Ghirardini E,Restelli E,Morini R,Bertani I,Ortolan D,Perrucci F,Pozzi D,Matteoli M,Chiesa R

doi

10.1371/journal.ppat.1009174

subject

Has Abstract

pub_date

2020-12-22 00:00:00

pages

e1009174

issue

12

eissn

1553-7366

issn

1553-7374

pii

PPATHOGENS-D-20-02629

journal_volume

16

pub_type

已发布勘误
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    abstract::Pomalidomide (Pom) is an immunomodulatory drug that has efficacy against Kaposi's sarcoma, a tumor caused by Kaposi's sarcoma-associated herpesvirus (KSHV). Pom also induces direct cytotoxicity in primary effusion lymphoma (PEL), a B-cell malignancy caused by KSHV, in part through downregulation of IRF4, cMyc, and CK1...

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    authors: Holden MT,Heather Z,Paillot R,Steward KF,Webb K,Ainslie F,Jourdan T,Bason NC,Holroyd NE,Mungall K,Quail MA,Sanders M,Simmonds M,Willey D,Brooks K,Aanensen DM,Spratt BG,Jolley KA,Maiden MC,Kehoe M,Chanter N,Bentl

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  • Neutrophils use superoxide to control bacterial infection at a distance.

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  • Candida albicans white and opaque cells undergo distinct programs of filamentous growth.

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    authors: Si H,Hernday AD,Hirakawa MP,Johnson AD,Bennett RJ

    更新日期:2013-03-01 00:00:00

  • Horizontal versus familial transmission of Helicobacter pylori.

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  • TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance.

    abstract::Triggering receptor expressed on myeloid cells-1 (TREM-1) is a potent amplifier of pro-inflammatory innate immune reactions. While TREM-1-amplified responses likely aid an improved detection and elimination of pathogens, excessive production of cytokines and oxygen radicals can also severely harm the host. Studies add...

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  • A major determinant of cyclophilin dependence and cyclosporine susceptibility of hepatitis C virus identified by a genetic approach.

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  • Creating an arsenal of Adeno-associated virus (AAV) gene delivery stealth vehicles.

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    authors: Smith JK,Agbandje-McKenna M

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  • Transcriptional regulation by protein kinase A in Cryptococcus neoformans.

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  • A conserved NS3 surface patch orchestrates NS2 protease stimulation, NS5A hyperphosphorylation and HCV genome replication.

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  • Cryptosporidium Lactate Dehydrogenase Is Associated with the Parasitophorous Vacuole Membrane and Is a Potential Target for Developing Therapeutics.

    abstract::The apicomplexan, Cryptosporidium parvum, possesses a bacterial-type lactate dehydrogenase (CpLDH). This is considered to be an essential enzyme, as this parasite lacks the Krebs cycle and cytochrome-based respiration, and mainly-if not solely, relies on glycolysis to produce ATP. Here, we provide evidence that in ext...

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    authors: Lang F,Singh RK,Pei Y,Zhang S,Sun K,Robertson ES

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  • HIV-1 buds predominantly at the plasma membrane of primary human macrophages.

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    authors: Welsch S,Keppler OT,Habermann A,Allespach I,Krijnse-Locker J,Kräusslich HG

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  • Reduced accumulation of defective viral genomes contributes to severe outcome in influenza virus infected patients.

    abstract::Influenza A virus (IAV) infection can be severe or even lethal in toddlers, the elderly and patients with certain medical conditions. Infection of apparently healthy individuals nonetheless accounts for many severe disease cases and deaths, suggesting that viruses with increased pathogenicity co-circulate with pandemi...

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  • Constraints to genetic exchange support gene coadaptation in a tripartite RNA virus.

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  • Extracellular vesicles from Kaposi Sarcoma-associated herpesvirus lymphoma induce long-term endothelial cell reprogramming.

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  • A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors.

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  • Influence of an immunodominant herpes simplex virus type 1 CD8+ T cell epitope on the target hierarchy and function of subdominant CD8+ T cells.

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    更新日期:2017-12-04 00:00:00

  • Cooperation between Epstein-Barr virus immune evasion proteins spreads protection from CD8+ T cell recognition across all three phases of the lytic cycle.

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    authors: Abdelrahman Y,Ouellette SP,Belland RJ,Cox JV

    更新日期:2016-08-30 00:00:00

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  • The virulence protein SopD2 regulates membrane dynamics of Salmonella-containing vacuoles.

    abstract::Salmonella enterica serovar Typhimurium is a Gram-negative bacterial pathogen causing gastroenteritis in humans and a systemic typhoid-like illness in mice. The capacity of Salmonella to cause diseases relies on the establishment of its intracellular replication niche, a membrane-bound compartment named the Salmonella...

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    authors: Schroeder N,Henry T,de Chastellier C,Zhao W,Guilhon AA,Gorvel JP,Méresse S

    更新日期:2010-07-15 00:00:00

  • A systematic map of genetic variation in Plasmodium falciparum.

    abstract::Discovering novel genes involved in immune evasion and drug resistance in the human malaria parasite, Plasmodium falciparum, is of critical importance to global health. Such knowledge may assist in the development of new effective vaccines and in the appropriate use of antimalarial drugs. By performing a full-genome s...

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    authors: Kidgell C,Volkman SK,Daily J,Borevitz JO,Plouffe D,Zhou Y,Johnson JR,Le Roch K,Sarr O,Ndir O,Mboup S,Batalov S,Wirth DF,Winzeler EA

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  • Anopheles gambiae PGRPLC-mediated defense against bacteria modulates infections with malaria parasites.

    abstract::Recognition of peptidoglycan (PGN) is paramount for insect antibacterial defenses. In the fruit fly Drosophila melanogaster, the transmembrane PGN Recognition Protein LC (PGRP-LC) is a receptor of the Imd signaling pathway that is activated after infection with bacteria, mainly Gram-negative (Gram-). Here we demonstra...

    journal_title:PLoS pathogens

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    doi:10.1371/journal.ppat.1000542

    authors: Meister S,Agianian B,Turlure F,Relógio A,Morlais I,Kafatos FC,Christophides GK

    更新日期:2009-08-01 00:00:00

  • Competent but complex communication: The phenomena of pheromone-responsive plasmids.

    abstract::Enterococci are robust gram-positive bacteria that are found in a variety of surroundings and that cause a significant number of healthcare-associated infections. The genus possesses a high-efficiency pheromone-responsive plasmid (PRP) transfer system for genetic exchange that allows antimicrobial-resistance determina...

    journal_title:PLoS pathogens

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    doi:10.1371/journal.ppat.1008310

    authors: Sterling AJ,Snelling WJ,Naughton PJ,Ternan NG,Dooley JSG

    更新日期:2020-04-02 00:00:00

  • Trichodysplasia spinulosa-Associated Polyomavirus Uses a Displaced Binding Site on VP1 to Engage Sialylated Glycolipids.

    abstract::Trichodysplasia spinulosa-associated Polyomavirus (TSPyV) was isolated from a patient suffering from trichodysplasia spinulosa, a skin disease that can appear in severely immunocompromised patients. While TSPyV is one of the five members of the polyomavirus family that are directly linked to a human disease, details a...

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    doi:10.1371/journal.ppat.1005112

    authors: Ströh LJ,Gee GV,Blaum BS,Dugan AS,Feltkamp MC,Atwood WJ,Stehle T

    更新日期:2015-08-24 00:00:00

  • Proteome-wide analysis of CD8+ T cell responses to EBV reveals differences between primary and persistent infection.

    abstract::Human herpesviruses are antigenically rich agents that induce strong CD8+T cell responses in primary infection yet persist for life, continually challenging T cell memory through recurrent lytic replication and potentially influencing the spectrum of antigen-specific responses. Here we describe the first lytic proteom...

    journal_title:PLoS pathogens

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    doi:10.1371/journal.ppat.1007110

    authors: Forrest C,Hislop AD,Rickinson AB,Zuo J

    更新日期:2018-09-24 00:00:00