Whole blood mRNA expression-based targets to discriminate active tuberculosis from latent infection and other pulmonary diseases.

abstract：:One of the potential antibiofilm strategies is to use lytic phages and phage-derived polysaccharide depolymerases. The idea is to uncover bacteria embedded in the biofilm matrix making them accessible and vulnerable to antibacterials and the immune system. Here we present the antibiofilm efficiency of lytic phage KP34...

journal_title：Scientific reports

authors： Latka A,Drulis-Kawa Z

更新日期：2020-11-23 00:00:00

abstract：:Atherosclerotic coronary artery disease (CAD) is the number one cause of death worldwide. The majority of CAD-induced deaths are due to the rupture of vulnerable plaques. Accurate assessment of plaques is crucial to optimize treatment and prevent death in patients with CAD. Current diagnostic techniques are often limi...

journal_title：Scientific reports

authors： Li J,Ma T,Mohar D,Steward E,Yu M,Piao Z,He Y,Shung KK,Zhou Q,Patel PM,Chen Z

更新日期：2015-12-18 00:00:00

abstract：:Human group-specific component protein (Gc protein) is a multifunctional serum protein which has three common allelic variants, Gc1F, Gc1S and Gc2 in humans. Gc1 contains an O-linked trisaccharide [sialic acid-galactose-N-acetylgalactosamine (GalNAc)] on the threonine420 (Thr420) residue and can be converted to a pote...

journal_title：Scientific reports

authors： Nabeshima Y,Abe C,Kawauchi T,Hiroi T,Uto Y,Nabeshima YI

更新日期：2020-11-05 00:00:00

abstract：:A negative correlation between body size and the latitudinal temperature gradient is well established for extant terrestrial endotherms but less so in the fossil record. Here we analyze the middle Eocene site of Geiseltal (Germany), whose record is considered to span ca. 5 Myrs of gradual global cooling, and generate ...

journal_title：Scientific reports

authors： Ring SJ,Bocherens H,Wings O,Rabi M

更新日期：2020-03-04 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Makino E,Klodnitsky H,Leonard J,Lillie J,Lund TC,Marshall J,Nietupski J,Orchard PJ,Miller WP,Phaneuf C,Tietz D,Varban ML,Donovan M,Belenki A

更新日期：2018-03-19 00:00:00

abstract：:This study aimed to investigate the basilar artery (BA) geometric changes in a longitudinal study. 154 subjects with normal vertebrobasilar arterial systems on magnetic resonance angiography were assigned into two groups: 1) non-dominant vertebral artery (VA) and 2) VA dominance. We defined the dominant VA as either t...

journal_title：Scientific reports

authors： Ngo MT,Kwak HS,Chung GH

更新日期：2020-06-01 00:00:00

abstract：:Dinosaurs thrived and reproduced in various regions worldwide, including the Arctic. In order to understand their nesting in diverse or extreme environments, the relationships between nests, nesting environments, and incubation methods in extant archosaurs were investigated. Statistical analyses reveal that species of...

journal_title：Scientific reports

authors： Tanaka K,Zelenitsky DK,Therrien F,Kobayashi Y

更新日期：2018-03-15 00:00:00

abstract：:Recent reports regarding the re-emergence of parasite sensitivity to chloroquine call for a new consideration of this drug as an interesting complementary tool in malaria elimination efforts, given its good safety profile and long half-life. A randomized (2:1), single-blind, placebo-controlled trial was conducted in M...

journal_title：Scientific reports

authors： Galatas B,Nhamussua L,Candrinho B,Mabote L,Cisteró P,Gupta H,Rabinovich R,Menéndez C,Macete E,Saute F,Mayor A,Alonso P,Bassat Q,Aide P

更新日期：2017-05-02 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) patients have poor prognosis and poor response to treatment. This is largely due to PDAC being associated with a dense and active stroma and tumor fibrosis (desmoplasia). Desmoplasia is characterized by excessive degradation and formation of the extracellular matrix (ECM) genera...

journal_title：Scientific reports

authors： Willumsen N,Ali SM,Leitzel K,Drabick JJ,Yee N,Polimera HV,Nagabhairu V,Krecko L,Ali A,Maddukuri A,Moku P,Ali A,Poulose J,Menon H,Pancholy N,Costa L,Karsdal MA,Lipton A

更新日期：2019-12-24 00:00:00

abstract：:We investigate the impact of borders on the topology of spatially embedded networks. Indeed territorial subdivisions and geographical borders significantly hamper the geographical span of networks thus playing a key role in the formation of network communities. This is especially important in scientific and technologi...

journal_title：Scientific reports

authors： Cerina F,Chessa A,Pammolli F,Riccaboni M

更新日期：2014-04-01 00:00:00

abstract：:Global exponential increase in levels of Photovoltaic (PV) module waste is an increasing concern. The purpose of this study is to investigate if there is energy value in the polymers contained within first-generation crystalline silicon (c-Si) PV modules to help contribute positively to recycling rates and the circula...

journal_title：Scientific reports

authors： Farrell C,Osman AI,Zhang X,Murphy A,Doherty R,Morgan K,Rooney DW,Harrison J,Coulter R,Shen D

更新日期：2019-03-27 00:00:00

abstract：:Mutations in the TGFβR2 gene have been associated with a life threatening risk of aortic dissection but no arrhythmic death has been previously reported. Two young females carrying a TGFβR2 mutation, initially diagnosed as Marfan syndrome or Loeys Dietz syndrome, presented sudden death with autopsy ruling out dissecti...

journal_title：Scientific reports

authors： Extramiana F,Milleron O,Elbitar S,Uccellini A,Langeois M,Spentchian M,Delorme G,Arnoult F,Denjoy I,Bouleti C,Fressart V,Iserin F,Maison-Blanche P,Abifadel M,Leenhardt A,Boileau C,Jondeau G

更新日期：2018-08-29 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is one of the most common respiratory diseases. Yihuo Huatan Formula (YHF), as a proven Chinese Herbal Medicine (CHM), has been verified to be effective in the treatment of stable COPD through years' of practice. Nevertheless, its working mechanism is still unclear. We soug...

journal_title：Scientific reports

authors： Zhang XW,Liu W,Jiang HL,Mao B

更新日期：2019-09-17 00:00:00

abstract：:The Turin Shroud is traditionally considered to be the burial cloth in which the body of Jesus Christ was wrapped after his death approximately 2000 years ago. Here, we report the main findings from the analysis of genomic DNA extracted from dust particles vacuumed from parts of the body image and the lateral edge use...

journal_title：Scientific reports

authors： Barcaccia G,Galla G,Achilli A,Olivieri A,Torroni A

更新日期：2015-10-05 00:00:00

abstract：:We wanted to determine whether subjective sleep disturbance was associated with serum glycated hemoglobin (HbA1c) in people with type 2 diabetes mellitus. In total, 944 randomly-selected people with diabetes completed the Chinese version of the Pittsburgh Sleep Quality Index (PSQI). Participants' glycaemia was assesse...

journal_title：Scientific reports

authors： Xu C,Zhang P,Xiang Q,Chang G,Zhang M,Zhang L,Li T,Qiao C,Qin Y,Lou P

更新日期：2019-10-03 00:00:00

abstract：:Urban water supplies are critical to the growth of the city and the wellbeing of its citizens. However, these supplies can be vulnerable to hydrological extremes, such as droughts and floods, especially if they are the main source of water for the city. Maintaining these supplies and preparing for future conditions is...

journal_title：Scientific reports

authors： Obringer R,Nateghi R

更新日期：2018-03-26 00:00:00

abstract：:Aquaculture has become imperative to cover the demands for dietary animal protein. Simultaneously, it has to overcome prejudices from excessive use of antibiotics and environmental impacts. Natural supplements are traditionally applied orally. In this study, we demonstrated another pathway: the gills. Humic substances...

journal_title：Scientific reports

authors： Lieke T,Steinberg CEW,Pan B,Perminova IV,Meinelt T,Knopf K,Kloas W

更新日期：2021-01-08 00:00:00

abstract：:All-inorganic visibly-transparent energy-harvesting clear laminated glass windows are the most practical solution to boosting building-integrated photovoltaics (BIPV) energy outputs significantly while reducing cooling- and heating-related energy consumption in buildings. By incorporating luminophore materials into la...

journal_title：Scientific reports

authors： Alghamedi R,Vasiliev M,Nur-E-Alam M,Alameh K

更新日期：2014-10-16 00:00:00

abstract：:For N indistinguishable bosons or fermions impinged on a M-port Haar-random unitary network the average probability to count n 1, … n r particles in a small number r ≪ N of binned-together output ports takes a Gaussian form as N ≫ 1. The discovered Gaussian asymptotic law is the well-known asymptotic law for distingui...

journal_title：Scientific reports

authors： Shchesnovich VS

更新日期：2017-02-16 00:00:00

abstract：:Stimuli presented at short temporal delays before functional magnetic resonance imaging (fMRI) can have a robust impact on the organization of synchronous activity in resting state networks. This presents an opportunity to investigate how sensory, affective and cognitive stimuli alter functional connectivity in rodent...

journal_title：Scientific reports

authors： Pompilus M,Colon-Perez LM,Grudny MM,Febo M

更新日期：2020-11-16 00:00:00

abstract：:Recently, the organic functionalization of polyoxometalates (POMs) has drawn increasing interest, and an easy and effective route to achieve organic derivatives is of great importance. Herein, the first reported synthesis of a tosyl ester derivative of the polyoxometalate (Bu4N)2[V6O13{(OCH2)3CCH2SO3C7H4}2]·2.5CH3CN (...

journal_title：Scientific reports

authors： Jia H,Li Q,Bayaguud A,She S,Huang Y,Chen K,Wei Y

更新日期：2017-10-02 00:00:00

abstract：:Graphene, a honeycomb lattice of carbon atoms ruled by tight-binding interaction, exhibits extraordinary electronic properties due to the presence of Dirac cones within its band structure. These intriguing singularities have naturally motivated the discovery of their classical analogues. In this work, we present a gen...

journal_title：Scientific reports

authors： Yves S,Lemoult F,Fink M,Lerosey G

更新日期：2017-11-10 00:00:00

abstract：:Although plants are essentially sessile in nature, these organisms are very much in tune with their environment and are capable of a variety of movements. This may come as a surprise to many non-botanists, but not to Charles Darwin, who reported that plants do produce movements. Following Darwin's specific interest on...

journal_title：Scientific reports

authors： Guerra S,Peressotti A,Peressotti F,Bulgheroni M,Baccinelli W,D'Amico E,Gómez A,Massaccesi S,Ceccarini F,Castiello U

更新日期：2019-11-12 00:00:00

abstract：:Phosphoinositide-3 kinase (PI3K) signaling is important for the survival of numerous cell types and class IA of PI3K is specifically required for the development of B cells but not for T cell development. Here, we show that class IA PI3K-mediated signals induce the expression of the transcription factor Pax5, which pl...

journal_title：Scientific reports

authors： Abdelrasoul H,Werner M,Setz CS,Okkenhaug K,Jumaa H

更新日期：2018-01-22 00:00:00

abstract：:The strong age dependency of neonatal systemic infection with Escherichia coli K1 can be replicated in the neonatal rat. Gastrointestinal (GI) colonization of two-day-old (P2) rats leads to invasion of the blood within 48 h of initiation of colonization; pups become progressively less susceptible to infection over the...

journal_title：Scientific reports

authors： Birchenough GM,Dalgakiran F,Witcomb LA,Johansson ME,McCarthy AJ,Hansson GC,Taylor PW

更新日期：2017-03-06 00:00:00

abstract：:Panax ginseng (GS) and Veratrum nigrum (VN) are representative of incompatible pairs in "eighteen antagonistic medicaments" that have been recorded in the Chinese medicinal literature for over 2,000 years. However, evidence linking interference effects with combination use is scare. Based on the estrogen-like effect o...

journal_title：Scientific reports

authors： Xu Y,Ding J,An JN,Qu YK,Li X,Ma XP,Zhang YM,Dai GJ,Lin N

更新日期：2016-05-27 00:00:00

abstract：:Diatoms are among the most diverse eukaryotic microorganisms on Earth, they are responsible for a large fraction of primary production in the oceans and can be found in different habitats. Pseudo-nitzschia are marine planktonic diatoms responsible for blooms in coastal and oceanic waters. We analyzed the transcriptome...

journal_title：Scientific reports

authors： Di Dato V,Musacchia F,Petrosino G,Patil S,Montresor M,Sanges R,Ferrante MI

更新日期：2015-07-20 00:00:00

abstract：:Seagrass meadows are among the four most productive marine ecosystems in the world. Zostera japonica (Z. japonica) is the most widely distributed species of seagrass in China. However, there is no reference genome or transcriptome available for Z. japonica, impeding progress in functional genomic and molecular ecology...

journal_title：Scientific reports

authors： Chen S,Qiu G,Yang M

更新日期：2019-10-10 00:00:00

abstract：:In the cochlea, mammals maintain a uniquely high endolymphatic potential (EP), which is not observed in other vertebrate groups. However, a high [K+] is always present in the inner ear endolymph. Here, we show that Kir4.1, which is required in the mammalian stria vascularis to generate the highly positive EP, is absen...

journal_title：Scientific reports

authors： Wilms V,Köppl C,Söffgen C,Hartmann AM,Nothwang HG

更新日期：2016-09-29 00:00:00

abstract：:Methylated non-CpGs (mCpH; H means A, C, and T) have emerged as key epigenetic marks in mammalian embryonic stem cells (ESCs) and neurons, regulating cell type-specific functions. In these two cell types, mCpHs show distinct motifs and correlations to transcription that could be a key in understanding the cell type-sp...

journal_title：Scientific reports

authors： Lee JH,Park SJ,Nakai K

更新日期：2017-09-12 00:00:00