Abstract:
BACKGROUND:This meta-analysis aimed to evaluate the prognostic value of the systemic inflammation response index (SIRI) in malignancy based on existing evidence. METHODS:We searched for relevant literature published in the electronic databases PubMed, Web of Science, Cochrane Library, and Embase before April 10, 2020. Hazard ratios (HR) and corresponding 95% confidence intervals (CI) were calculated and pooled to evaluate the relationship between SIRI and malignancy outcomes. RESULTS:We included 14 articles, describing 6,035 patients. Our findings revealed that patients with high SIRI had worse overall survival (OS) (HR = 2.20, 95% CI: 1.85-2.62, P < .001), disease-free survival (DFS) (HR: 1.92, 95% CI: 1.49-2.48, P < .001), time-to-progression (TTP) (HR: 2.00, 95% CI: 1.55-2.58, P < .001), progression-free survival (PFS) (HR: 1.73, 95% CI: 1.38-2.16, P < .001), cancer-specific survival (CSS) (HR: 3.57, 95% CI: 2.25-5.68, P < 0.001), disease-specific survival (DSS) (HR: 1.99, 95% CI: 1.46 - 2.72, P < .001), and metastasis-free survival (MFS) (HR: 2.26, 95% CI: 1.28-3.99, P = .005) than patients with low SIRI. The correlation between SIRI and OS did not change in a subgroup analysis. Meta-regression indicated that heterogeneity may be related to differences in primary therapy strategies. Sensitivity analysis suggested that our results were reliable. CONCLUSIONS:SIRI could be used as a useful predictor of poor prognosis during malignancy treatment.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Wei L,Xie H,Yan Pdoi
10.1097/MD.0000000000023486subject
Has Abstractpub_date
2020-12-11 00:00:00pages
e23486issue
50eissn
0025-7974issn
1536-5964pii
00005792-202012110-00061journal_volume
99pub_type
杂志文章,meta分析相关文献
MEDICINE文献大全abstract:UNLABELLED:Tubulointerstitial fibrosis and tubular atrophy play a crucial role in the pathogenesis of chronic kidney disease (CKD). They are also major determinants in chronic kidney disease development and progression in patients with primary renal diseases characterized by persistent or recurrent proteinuria. The pur...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001746
更新日期:2015-10-01 00:00:00
abstract:INTRODUCTION:Cardiac myxomas are the most frequent primary cardiac tumor in adults. The incidence in pediatric patients is extremely low. Heavy calcification of an atrial myxoma is uncommon in children. CASE PRESENTATION:An 18-month-old boy was admitted for a significant precordial systolic murmur. Transthoracic echoc...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011073
更新日期:2018-06-01 00:00:00
abstract::The effect of intracranial internal carotid artery (ICA) calcification on cognitive impairment is uncertain. Our objective was to investigate whether intracranial ICA calcification is a significant cognitive predictor for cognitive impairment. Global cognition and degrees of intracranial ICA calcification of 579 subje...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001546
更新日期:2015-09-01 00:00:00
abstract::Meckel diverticulum is the most prevalent congenital abnormality of the gastrointestinal tract in children. The aim of this study was to review and analyze clinical data on the diagnosis and management of Meckel diverticulum in pediatric patients. The records of 102 pediatric patients (<14 years old) who underwent sur...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007760
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:No systematic review has been published in English of Dengzhanxixin (DZXX) injection for cerebral infarction. The aim of this systematic review was to assess the effects and safety of DZXX injection for cerebral infarction. METHODS:Eight databases were searched from their inception. Randomized controlled tr...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000007674
更新日期:2017-08-01 00:00:00
abstract:PURPOSE:To find out whether the intramedullary fixations are superior to the extramedullary fixations in treating unstable femoral intertrochanteric fractures (UFIFs). METHODS:The meta-analysis of randomized controlled trials (RCTs) was conducted by searching the PubMed, Cochrane Library, and Embase databases to evalu...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000017010
更新日期:2019-09-01 00:00:00
abstract:ABSTRACT:The International Society on Thrombosis and Haemostasis (ISTH) scoring system has been used for diagnosing overt disseminated intravascular coagulation (DIC). However, the cut-off points of fibrin-related markers remain unclear. The ability of the ISTH DIC score and Multiple Organ Dysfunction (MODS) score to p...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000023831
更新日期:2020-12-24 00:00:00
abstract::The study aim is to compare anal intraepithelial neoplasia (AIN) progression and regression rates in a cytology inception cohort to estimates based on the subcohort referred for ≥1 high-resolution anoscopies (HRAs).A cytology-based retrospective cohort was assembled including the anal cytology histories and invasive a...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001476
更新日期:2015-09-01 00:00:00
abstract:BACKGROUND:Dry eye disease is a common eye disease mainly manifests with eye fatigue, foreign body sensation, dry and astringent eyes and other symptoms. Growing evidence shows that qiming granule may have beneficial effects on the clinical treatment of dry eye disease. However, no systematic review and meta-analysis c...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000017121
更新日期:2019-09-01 00:00:00
abstract::The benefits of an anesthesia pre-operative evaluation clinic (APEC) based on outpatients are well described in previous literatures. In the majority of hospitals in South Korea, preoperative anesthetic evaluation for surgical patients is limited to hospitalized patients on the day before surgery. Thus, we would like ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017634
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Chronic pelvic inflammatory disease (CPID) is a difficult-to-treat gynaecological disorder, which has complex etiologies, among married women. In recent years, moxibustion has gradually shown its clinical advantages and been more and more widely used In China. The protocol is try to synthesize and assess the...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021925
更新日期:2020-08-28 00:00:00
abstract:BACKGROUND:This review aims to evaluate the effectiveness and safety of acupuncture treatment for reducing opioid consumption in patients with chronic pain. METHODS:We will search the following electronic databases from their inception to November 2019: MEDLINE, EMBASE, the Cochrane Central Register of Controlled Tria...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000018237
更新日期:2019-12-01 00:00:00
abstract::The occurrence of anastomotic leakage (AL) remains a major concern in the early postoperative stage. Because of the relatively high morbidity and mortality of AL in patients with laparoscopic low rectal cancer who receive an anterior resection, a fecal diverting method is usually introduced. The Valtrac™-secured intra...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000224
更新日期:2014-12-01 00:00:00
abstract::Atrial fibrillation (AF), the most common cardiac arrhythmia, is a major risk factor for thromboembolic events, especially ischemic stroke. Catheter ablation is an effective method to maintain sinus rhythm in patients with AF. Although some observational studies have shown a relatively lower stroke rate after catheter...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000008479
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Primary immunoglobulin light chain amyloidosis (AL amyloidosis) is a plasma cell disorder which mainly affects heart, kidneys, liver, and peripheral nervous system. Cases of atypical AL amyloidosis presented as spontaneous vertebral compression fractures have been rarely reported, and data about the manageme...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000004603
更新日期:2016-09-01 00:00:00
abstract:RATIONALE:The occurrence of bleeding and hematoma from bone metastasis of hepatocellular carcinoma (HCC) is extremely rare. PATIENT CONCERNS:We present a case of scapular metastasis of HCC in a 69-year-old man who presented with acute bleeding and hematoma. DIAGNOSES:Chest computed tomography showed a large hematoma ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008736
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:Perimenopausal insomnia (PI) is one of the most common complaints in women. Acupuncture is used to treat PI increasingly considering its less side effect. The subject of this study is to explore the effectiveness and safety of acupuncture for PI. METHODS:All the randomized controlled trials(RCT) literatures...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000011083
更新日期:2018-06-01 00:00:00
abstract::The aim of this study was to explore the impact of 3% hypertonic saline (HS) intragastric administration for patients who underwent upper gastrointestinal surgery.During the postoperative period, 3% HS has been suggested as a means to improve the intestinal edema and reduce gastrointestinal complications.The medical r...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006121
更新日期:2017-03-01 00:00:00
abstract:RATIONALE:Transforaminal epidural steroid injection (TFESI) is a conservative method to treat back pain due to radiculopathy. However, epidural hematoma can occur after the procedure by various mechanisms, which can cause serious complications. PATIENT CONCERNS:An 82-year-old man with spinal stenosis was treated with ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016654
更新日期:2019-07-01 00:00:00
abstract:RATIONALE:Nivolumab is a monoclonal IgG antibody blocking programmed death receptor-1 (PD1), leading to restoration of the natural T-cell-mediated immune response against the cancer cells. However, it also causes plenty of autoimmune-related adverse events, which often involves endocrine system. PATIENT CONCERNS:A 54-...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000008426
更新日期:2017-11-01 00:00:00
abstract::Deep sternal wound infection is a severe complication after open heart surgery. According to the different severity and dimensions of the deep sternal wound infection, the treatment method is different. In this study, we aimed to describe our experience with the rectus abdominis myocutaneous flap for large sternal wou...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006391
更新日期:2017-04-01 00:00:00
abstract::Primary oculocerebral non-Hodgkin lymphoma (NHL) of the immunocompetent patient is associated with significant morbidity and mortality, but early diagnosis and follow-up may improve prognosis. The eye, anatomically and embryologically part of the central nervous system (CNS), can be the primary site of the lymphomatou...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/01.md.0000134850.35118.46
更新日期:2004-07-01 00:00:00
abstract::We created a model to predict the development of liver carcinogenesis in patients with chronic hepatitis B (CHB) undergoing entecavir (ETV) therapy and to validate the accuracy using an independent dataset.A total of 328 CHB subjects were analyzed. Subjects were randomly assigned into 2 groups: the training group (n =...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004832
更新日期:2016-09-01 00:00:00
abstract::The aim of the study was to evaluate the efficacy custom 3D-printed osteosynthesis plates in the treatment of intercondylar humeral fractures.Thirteen patients with distal intercondylar humeral fractures were randomized to undergo surgery using either conventional plates (n = 7) or 3D-printed plates (n = 6) at our ins...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000002461
更新日期:2016-01-01 00:00:00
abstract:INTRODUCTION:This study is a prospective, assessor-blinded, parallel-group, randomized controlled pilot trial to explore the effectiveness of 12-week adjuvant moxibustion therapy for arthralgia in menopausal females at stage I to III breast cancer on aromatase inhibitor (AI) administration, compared with those receivin...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000017260
更新日期:2019-09-01 00:00:00
abstract::Laparoscopic inguinal herniorrhaphy has been well established for the management of primary and recurrent inguinal hernias. Single-incision laparoscopic surgery (SILS) has now been accepted as a less invasive alternative to conventional laparoscopic surgery. However, commercially available access devices for SILS had ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021787
更新日期:2020-08-21 00:00:00
abstract::Few studies have yet investigated the possible association between high-density lipoprotein cholesterol (HDL-C) and kidney function in elderly patients with primary hypertension. Accordingly, the aim of the present study was to evaluate the relationship between HDL-C and kidney function in elderly hypertension. A tota...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000651
更新日期:2015-04-01 00:00:00
abstract::Signet ring cell carcinoma (SRC) is a poorly differentiated cancer of the stomach. Generally, poorly differentiated cancer is believed to show poor prognosis and aggressive behavior. Recently, however, there is debate on the aggressiveness of SRC in early gastric cancer (EGC). We therefore studied postoperation biopsi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007532
更新日期:2017-08-01 00:00:00
abstract:RATIONALE:Insignifificant, asymmetrical or lack of labial tubercle often occurs after cleft lip surgery due to improper treatment of vermilion tissue. Especially in the cases of bilateral cleft lip, because of short front lip and insuffificient vermilion tissue, the median vermilion depression often occurs after surger...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016161
更新日期:2019-07-01 00:00:00
abstract:RATIONALE:Diffuse large B-cell lymphoma (DLBCL) and extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) belong to Non-Hodgkin's lymphoma (NHL). DLBCL rarely involves the orbit. MALT lymphomas, which account for 8.0% of NHLs, rarely involve parotid gland, trachea and bronchus. PATIENT C...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010845
更新日期:2018-05-01 00:00:00