COVID-19 Outbreak and Presymptomatic Transmission in Pilgrim Travelers Who Returned to Korea from Israel.

Abstract:

BACKGROUND:On February 21, 2020, 2 coronavirus disease 2019 (COVID-19) cases in pilgrim travelers from Korea to Israel were identified. We investigated the source of infection, clinical features of COVID-19, and transmission potential of presymptomatic and asymptomatic cases. METHODS:All 39 pilgrim travelers were aggressively tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Their clinical features and possible source of infection were investigated by interview and review of their medical records. Ten confirmed cases without symptoms at the first sampling dates were selected for follow-up reverse transcription polymerase chain reaction tests. RESULTS:Of 39 pilgrim travelers, 30 (77%) were positive for SARS-CoV-2. Among the 30 positive COVID-19 cases, 4 (13%) were asymptomatic. Available follow-up cycle threshold values from 10 cases gradually increased over time and were lower during the presymptomatic period than during the postsymptomatic period. Out of 328 contacts related to the COVID-19 cases in the pilgrim travelers, 22 additional cases (7%) were confirmed with SARS-CoV-2 infections. Three tertiary cases were identified to be transmitted by presymptomatic secondary cases. CONCLUSION:To prevent transmission of COVID-19, we need to focus on presymptomatic and asymptomatic cases, and massive testing for SARS-CoV-2 is required. More research about the possibility of presymptomatic transmission over 2 days before symptom onset is required.

journal_name

J Korean Med Sci

authors

Park JH,Jang JH,Lee K,Yoo SJ,Shin H

doi

10.3346/jkms.2020.35.e424

subject

Has Abstract

pub_date

2020-12-14 00:00:00

pages

e424

issue

48

eissn

1011-8934

issn

1598-6357

pii

35.e424

journal_volume

35

pub_type

杂志文章
  • Effect of small hairpin RNA targeting endothelin-converting enzyme-1 in monocrotaline-induced pulmonary hypertensive rats.

    abstract::The purpose of this study was to investigate the therapeutic effects of small hairpin RNA (shRNA) targeting endothelin-converting enzyme (ECE)-1 in monocrotaline (MCT)-induced pulmonary hypertensive rats. Ninty-four Sprague-Dawley rats were divided into three groups: control (n = 24), MCT (n = 35) and shRNA (n = 35). ...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2012.27.12.1507

    authors: Son JS,Kim KC,Kim BK,Cho MS,Hong YM

    更新日期:2012-12-01 00:00:00

  • Breastfeeding Knowledge, Attitude, and Practice among White-Collar and Blue-Collar Workers in Indonesia.

    abstract:BACKGROUND:Working status is identified as a major risk factor of poor breastfeeding practices among workers. This study aimed to evaluate the knowledge, attitude, and factors associated with breastfeeding practice among white-collar and blue-collar workers in Indonesia. METHODS:A cross-sectional study was performed i...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2019.34.e284

    authors: Basrowi RW,Sulistomo AW,Adi NP,Widyahening IS,Vandenplas Y

    更新日期:2019-11-25 00:00:00

  • Rapid increase of health care utilization and cost due to benign prostatic hyperplasia in Korean men: retrospective population-based analysis using the Health Insurance Review and Assessment service data.

    abstract::Using the Korean public health insurance database, we analyzed patients diagnosed as benign prostatic hyperplasia (BPH) from 2004 to 2008. Age and year-specific amount and seasonal variation of hospital visits (HV), duration of treatment (DT), the total and per capita amount of insurance payment (TAIP, PCIP) were eval...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2015.30.2.180

    authors: Son H,Park J,Song SH,Kang JY,Hong SK,Lee HM,Kim SH,Park BJ,Lee HL,Lee KS

    更新日期:2015-02-01 00:00:00

  • Hallervorden-Spatz syndrome in two siblings diagnosed by the clinical features and magnetic resonance imaging (MRI).

    abstract::Hallervorden-Spatz syndrome (HSS) is a heredodegenerative disorder characterized by both progressive pyramidal and extrapyramidal signs, dysarthric speech, and mental deterioration. No diagnostic biochemical test is yet available, and diagnosis of HSS can be confirmed only at autopsy by the characteristic neuropatholo...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1993.8.5.329

    authors: Kim DW,Choi Y,Kim KJ,Ko TS,Hwang YS,Kim IW

    更新日期:1993-10-01 00:00:00

  • A practical protocol for titrating "optimal" PEEP in acute lung injury: recruitment maneuver and PEEP decrement.

    abstract::This study was conducted to evaluate the effectiveness and safety of a practical protocol for titrating positive end-expiratory pressure (PEEP) involving recruitment maneuver (RM) and decremental PEEP. Seventeen consecutive patients with acute lung injury who underwent PEEP titration were included in the analysis. Aft...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2003.18.3.349

    authors: Suh GY,Kwon OJ,Yoon JW,Park SJ,Ham HS,Kang SJ,Koh WJ,Chung MP,Kim HJ

    更新日期:2003-06-01 00:00:00

  • Comparison of ertapenem and ceftriaxone therapy for acute pyelonephritis and other complicated urinary tract infections in Korean adults: a randomized, double-blind, multicenter trial.

    abstract::The efficacy and safety of ertapenem, 1 g once daily, were compared with that of ceftriaxone, 2 g once daily, for the treatment of adults with acute pyelonephritis (APN) and complicated urinary tract infections (cUTIs) in a prospective, multicenter, double-blinded, randomized study. After ≥ 3 days of parenteral study ...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.3346/jkms.2012.27.5.476

    authors: Park DW,Peck KR,Chung MH,Lee JS,Park YS,Kim HY,Lee MS,Kim JY,Yeom JS,Kim MJ

    更新日期:2012-05-01 00:00:00

  • Delays in Isolating Patients Admitted to Hospital with Pulmonary Tuberculosis in Korea.

    abstract:BACKGROUND:Delays in isolating patients admitted to hospital with active pulmonary tuberculosis (PTB) can contribute to nosocomial transmission; however, in Korea, patients with clinically diagnosed PTB are not routinely isolated while awaiting microbiological confirmation of the diagnosis. We aimed to assess the exten...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2019.34.e270

    authors: Heo DH,Seo JW,Kim JH,Chun JY,Jun KI,Kang CK,Moon SM,Song KH,Choe PG,Park WB,Bang JH,Kim ES,Park SW,Kim NJ,Oh MD,Kim HB

    更新日期:2019-11-11 00:00:00

  • Bizarre leiomyoma of the scrotum.

    abstract::Scrotal leiomyomas with atypical bizarre nuclei are rare, which might be misdiagnosed as malignant tumor. We describe a case of scrotal bizarre leiomyoma in a 65-yr-old man. The tumor was a 1 cm-sized, well circumscribed, oval mass arising from the tunica dartos muscle. Histologically, it was formed by whorling bundle...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2003.18.3.452

    authors: Kim NR,Sung CO,Han J

    更新日期:2003-06-01 00:00:00

  • Changes of Epidemiological Characteristics of Japanese Encephalitis Viral Infection and Birds as a Potential Viral Transmitter in Korea.

    abstract::Japanese encephalitis (JE) cases have been increasingly reported recently especially in Seoul and its vicinity. Pigs are known as amplifying host of JE virus (JEV), but do not play an important role in these recent events because pig-breeding is not common in Seoul. The distribution and the density of migratory birds ...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2018.33.e70

    authors: Bae W,Kim JH,Kim J,Lee J,Hwang ES

    更新日期:2018-02-26 00:00:00

  • Decreased gastric proliferation of foveolar epithelial cells after the eradication of Helicobacter pylori.

    abstract::Increased epithelial cell proliferation is associated with an increased risk of gastric carcinoma. Helicobacter pylori infection is an established risk factor for gastric cancer and the organism has recently been classified as a group I carcinogen by an IARC working group. In this study, we describe differences in gas...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1997.12.5.421

    authors: Jang TJ,Lee JI,Kim JR,Kim DH,Bae SH

    更新日期:1997-10-01 00:00:00

  • Prevalence and Duration of Acute Loss of Smell or Taste in COVID-19 Patients.

    abstract::Initially, acute loss of smell (anosmia) and taste (ageusia) was not considered important symptoms for coronavirus disease 2019 (COVID-19). To determine the prevalence of these symptoms and to evaluate their diagnostic significance, we (approximately 150 physicians of the Daegu Medical Association) prospectively colle...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2020.35.e174

    authors: Lee Y,Min P,Lee S,Kim SW

    更新日期:2020-05-11 00:00:00

  • Invasive cystic hypersecretory carcinoma of the breast: a case report.

    abstract::Cystic hypersecretory lesions of the breast are rare. These breast lesions include cystic hypersecretory hyperplasia (CHH), atypical CHH, and cystic hypersecretory carcinoma (CHC). The characteristic features are dilated ducts and cysts filled with thyroid colloid-like eosinophilic secretion. Only seven cases of invas...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2004.19.1.149

    authors: Lee JS,Lee YJ

    更新日期:2004-02-01 00:00:00

  • Clinical characteristics of acute viral lower respiratory tract infections in hospitalized children in Seoul, 1996-1998.

    abstract::This study was performed to investigate the etiologic agents, age distribution, clinical manifestations and seasonal occurrence of acute viral lower respiratory tract infections in children. We confirmed viral etiologies using nasopharyngeal aspirates in 237 patients of the ages of 15 years or younger who were hospita...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1999.14.4.405

    authors: Ahn KM,Chung SH,Chung EH,Koh YJ,Nam SY,Kim JH,Son JA,Park JY,Lee NY,Lee SI

    更新日期:1999-08-01 00:00:00

  • Imipenem-resistant Pseudomonas aeruginosa: risk factors for nosocomial infections.

    abstract::The aim of this study was to determine the risk factors for nosocomial infections of imipenem-resistant Pseudomonas aeruginosa (IRPA). A prospective case-control study was performed at a tertiary care hospital in Ankara from January to December 2004. The patients with nosocomial P. aeruginosa infection were included i...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2008.23.6.982

    authors: Onguru P,Erbay A,Bodur H,Baran G,Akinci E,Balaban N,Cevik MA

    更新日期:2008-12-01 00:00:00

  • Erratum: correction of 1.3 investigators in supplementary materials.

    abstract::[This corrects the article on p. 1308 in vol. 29, PMID: 25246752.]. ...

    journal_title:Journal of Korean medical science

    pub_type: 已发布勘误

    doi:10.3346/jkms.2015.30.1.118

    authors: Park JH,LOCAT Group.

    更新日期:2015-01-01 00:00:00

  • Psychological Status and Associated Factors among Korean Cancer Survivors: a Cross-Sectional Analysis of the Fourth & Fifth Korea National Health and Nutrition Examination Surveys.

    abstract::It is important to assess psychological distress after a diagnosis for cancer survivors, a population with a high risk for psychological distress. The aim of this study is to assess psychological distress among cancer survivors and to clarify the associated factors. In this cross-sectional analysis, data were obtained...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2016.31.7.1105

    authors: Choi KH,Park SM

    更新日期:2016-07-01 00:00:00

  • Clear-cell chondrosarcoma--a case report.

    abstract::Clear-cell chondrosarcoma, a recently specified entity, is a low-grade malignant tumor and has characteristic clinical, roentgenographic and pathologic findings which separate it from conventional chondrosarcoma and other benign tumors. Therefore, correct diagnosis is important from the viewpoint of both prognosis and...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.1989.4.3.155

    authors: Lee SD,Ahn GH,Chi JG,Ham EK

    更新日期:1989-09-01 00:00:00

  • Donor specific response of estrogen and progesterone on cultured human melanocytes.

    abstract::The mechanisms of estrogen and progesterone in human cutaneous pigmentation are largely unknown. The molecular identification of estrogen receptor (ER) and progesterone receptor (PR) in the human melanocytes is of great importance to understand the mechanisms. We performed immunocytochemistry analysis and demonstrated...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2002.17.1.58

    authors: Im S,Lee ES,Kim W,On W,Kim J,Lee M,Kang WH

    更新日期:2002-02-01 00:00:00

  • A phase III, randomized, double-blind, matched-pairs, active-controlled clinical trial and preclinical animal study to compare the durability, efficacy and safety between polynucleotide filler and hyaluronic acid filler in the correction of crow's feet: a

    abstract::The Rejuran® is a new filler product made from purified polynucleotides. Here we present data from an animal study and a clinical trial to examine the durability, efficacy and safety of the Rejuran® on crow's feet. For the animal study, 25 mice were divided into three groups: Group 1 received phosphate buffered saline...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章,随机对照试验,收录出版

    doi:10.3346/jkms.2014.29.S3.S201

    authors: Pak CS,Lee J,Lee H,Jeong J,Kim EH,Jeong J,Choi H,Kim B,Oh S,Kim I,Heo CY

    更新日期:2014-11-01 00:00:00

  • MERS-CoV Infection in a Pregnant Woman in Korea.

    abstract::Middle East respiratory syndrome (MERS) is a lethal respiratory disease - caused by MERS-coronavirus (MERS-CoV) which was first identified in 2012. Especially, pregnant women can be expected as highly vulnerable candidates for this viral infection. In May 2015, this virus was spread in Korea and a pregnant woman was c...

    journal_title:Journal of Korean medical science

    pub_type:

    doi:10.3346/jkms.2017.32.10.1717

    authors: Jeong SY,Sung SI,Sung JH,Ahn SY,Kang ES,Chang YS,Park WS,Kim JH

    更新日期:2017-10-01 00:00:00

  • Legislative Issues in Disclosing Financial Conflicts of Interest to Participants in Biomedical Research: Effectiveness and Methodology.

    abstract::This research focuses on the analysis regarding disclosure of financial conflicts of interest (FCOI) after Gelsinger v. University of Pennsylvania (Penn). The main legal issue was that the participants did not have enough opportunity to make an autonomous decision about participating in the research because he was not...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章,评审

    doi:10.3346/jkms.2017.32.12.1910

    authors: Kim JS

    更新日期:2017-12-01 00:00:00

  • Transcatheter closure of fenestration with detachable coils after the Fontan operation.

    abstract::We report our experience in 13 patients who underwent transcatheter closure of Fontan fenestration with the Cook detachable coils. These patients underwent the extracardiac type Fontan operation with a short conduit fenestration (n=7) or lateral tunnel type with a punch-hole fenestration (n=6). Fenestration closure wa...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2006.21.5.859

    authors: Kim SH,Kang IS,Huh J,Lee HJ,Yang JH,Jun TG

    更新日期:2006-10-01 00:00:00

  • A case of human cyclosporiasis causing traveler's diarrhea after visiting Indonesia.

    abstract::This is the first case of human cyclosporiasis reported in Korea. We detected the oocyst of Cyclospora cayetanensis from a 14-yr old girl who complained of persistent diarrhea after traveling to Indonesia. Round oocysts sized about 8 to 9 m with wrinkle on the wall were found in modified acid fast stained stool specim...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2003.18.5.738

    authors: Yu JR,Sohn WM

    更新日期:2003-10-01 00:00:00

  • Sphingosine 1-phosphate triggers apoptotic signal for B16 melanoma cells via ERK and caspase activation.

    abstract::The bioactive sphingolipid metabolite sphingosine 1-phosphate (S1P), recently was reported to induce apoptosis of some cancer cells and neurons, although it generally known to exert mitogenic and antiapoptotic effects. In this study, we investigated the effects of S1P on the cell growth, melanogenesis, and apoptosis o...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2007.22.2.298

    authors: Shin JH,Choi GS,Kang WH,Myung KB

    更新日期:2007-04-01 00:00:00

  • Seroprevalence of Opsonophagocytic Antibodies against Serotype Ia, Ib, II, III, and V Group B Streptococcus among Korean Population.

    abstract:BACKGROUND:Invasive Streptococcus agalactiae (group B streptococcus, GBS) infection most commonly occurs in infants; however, cases of GBS infection in adults, particularly in the elderly with significant underlying diseases, are being increasingly reported. We analyzed the serotype specific opsonophagocytic antibodies...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2018.33.e127

    authors: Lee JH,Kim HW,Kim KH

    更新日期:2018-04-16 00:00:00

  • Cowden's disease--a report on the first case in Korea and literature review.

    abstract::Cowden's disease, or multiple hamartoma syndrome, is an uncommon condition with characteristic mucocutaneous lesions associated with abnormalities of the breast, thyroid, and gastrointestinal tract. We describe a 32-year-old man with oral mucosal papillomatosis and plantar hyperkeratosis as a definite case of Cowden's...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章,评审

    doi:10.3346/jkms.1997.12.6.570

    authors: Lee HR,Moon YS,Yeom CH,Kim KW,Chun JY,Kim HK,Choi HS,Kim DK,Chung TS

    更新日期:1997-12-01 00:00:00

  • Pertussis seroprevalence in korean adolescents and adults using anti-pertussis toxin immunoglobulin G.

    abstract::This study was conducted to evaluate age-specific seroprevalence of pertussis in Korea and to formulate a strategy to prevent and reduce the incidence of pertussis. Residual serum samples of healthy adolescents and adults 11 yr of age or older were collected between July 2012 and December 2012, and anti-pertussis toxi...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2014.29.5.652

    authors: Lee SY,Han SB,Bae EY,Kim JH,Kang JH,Park YJ,Ma SH

    更新日期:2014-05-01 00:00:00

  • Atypical pathogens as etiologic agents in hospitalized patients with community-acquired pneumonia in Korea: a prospective multi-center study.

    abstract::Local epidemiologic data on the etiologies of patients hospitalized with community-acquired pneumonia (CAP) is needed to develop guidelines for clinical practice. This study was conducted prospectively to determine the proportion of atypical bacterial pathogens in adults patients hospitalized with CAP in Korea between...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章,多中心研究

    doi:10.3346/jkms.2006.21.4.602

    authors: Sohn JW,Park SC,Choi YH,Woo HJ,Cho YK,Lee JS,Sim HS,Kim MJ

    更新日期:2006-08-01 00:00:00

  • Rising incidence of hip fracture in Gwangju City and Chonnam Province, Korea.

    abstract::The purpose of study was to determine the incidence of hip fracture in 2001, to compare this with that of 1991, and to identify possible causes of change. Patients aged 50 yr or more living in Gwangju City and Chonnam Province, Korea, and who sustained a fracture of the hip during 2001 were investigated. Only patients...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2005.20.4.655

    authors: Rowe SM,Song EK,Kim JS,Lee JY,Park YB,Bae BH,Hur CI

    更新日期:2005-08-01 00:00:00

  • Trends in deceased organ donation and utilization in Korea: 2000-2009.

    abstract::Continuous efforts have been made by the organ donation and transplantation community in Korea to increase organ donation by the deceased. The authors detailed trends of organ donation and utilization over the past 10 yr using data provided by the KONOS. The yearly number of deceased donors has grown gradually since 2...

    journal_title:Journal of Korean medical science

    pub_type: 杂志文章

    doi:10.3346/jkms.2010.25.8.1122

    authors: Min SI,Kim SY,Park YJ,Min SK,Kim YS,Ahn C,Kim SJ,Ha J

    更新日期:2010-08-01 00:00:00