Abstract:
:Cardiovascular MRI has become an essential imaging modality in children with congenital heart disease (CHD) in the last 15-20 years. With use of appropriate sequences, it provides important information on cardiovascular anatomy, blood flow and function for initial diagnosis and post-surgical or -interventional monitoring in children. Although considered as more sophisticated and challenging than CT, in particular in neonates and infants, MRI is able to provide information on intra- and extracardiac haemodynamics, in contrast to CT. In recent years, four-dimensional (4-D) flow MRI has emerged as an additional MR technique for retrospective assessment and visualisation of blood flow within the heart and any vessel of interest within the acquired three-dimensional (3-D) volume. Its application in young children requires special adaptations for the smaller vessel size and faster heart rate compared to adolescents or adults. In this article, we provide an overview of 4-D flow MRI in various types of complex CHD in neonates and infants to demonstrate its potential indications and beneficial application for optimised individual cardiovascular assessment. We focus on its application in clinical routine cardiovascular workup and, in addition, show some examples with pathologies other than CHD to highlight that 4-D flow MRI yields new insights in disease understanding and therapy planning. We shortly review the essentials of 4-D flow data acquisition, pre- and post-processing techniques in neonates, infants and young children. Finally, we conclude with some details on accuracy, limitations and pitfalls of the technique.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Geiger J,Callaghan FM,Burkhardt BEU,Valsangiacomo Buechel ER,Kellenberger CJdoi
10.1007/s00247-020-04885-wsubject
Has Abstractpub_date
2020-12-11 00:00:00eissn
0301-0449issn
1432-1998pii
10.1007/s00247-020-04885-wpub_type
杂志文章abstract:BACKGROUND:Computed tomography (CT) is commonly used to evaluate suspected acute appendicitis. Although very effective, CT uses ionizing radiation, exposing patients to an increased risk of cancer. OBJECTIVE:This study assessed the potential for decreasing the field of view of the CT (and therefore the dose to the pat...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-016-3773-x
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:There is strong evidence that imaging with ultrasound and CT can be of substantial diagnostic value in the diagnosis of acute appendicitis in children, but there is limited information of the impact of imaging on the management of these patients and its possible effect on surgical findings. OBJECTIVE:We stu...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050023
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVE:The unicameral bone cyst (UBC) is a common cystic bone lesion seen in children. We review and summarize its MR findings, focusing on their appearance following contrast enhancement, and correlating them to known histologic features of UBC. SUBJECTS AND METHODS:A retrospective review of 20 cases (13 boys, 7 g...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470000258
更新日期:2000-08-01 00:00:00
abstract::Sakoda complex is a rare but distinct combination of birth defects consisting of a basal cephalocele, agenesis of the corpus callosum, and midline cleft lip/palate. It has been reported in association with ophthalmologic abnormalities, cognitive deficits and severe epilepsy. Here we describe both prenatal and postnata...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-019-04491-5
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Structural size in the neonatal brain is of clinical importance. Cranial ultrasonography (cUS) is the primary method used for evaluating the neonatal brain and it is important to know whether linear measurements made using this technique are accurate. OBJECTIVE:To compare linear measurements of different ce...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-007-0485-2
更新日期:2007-07-01 00:00:00
abstract:: ...
journal_title:Pediatric radiology
pub_type: 评论,信件
doi:10.1007/s00247-019-04341-4
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Nusinersen, the only treatment approved by the United States Food and Drug Administration for spinal muscular atrophy (SMA), is delivered intrathecally. Many children with SMA have extensive spinal instrumentation and deformities, often precluding the use of standard approaches for gaining intrathecal access...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-017-4031-6
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Infantile Blount disease is a developmental condition characterized by disorganized endochondral ossification in the medial aspect of the proximal tibial physis. OBJECTIVE:To describe the MR imaging abnormalities in the proximal tibia, distal femur, menisci and ligaments of children with infantile Blount di...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-013-2686-1
更新日期:2013-10-01 00:00:00
abstract::The objective of this study was to compare the quality of conventional and helical computed tomography (CT) images in children unable to breath-hold. Sixteen patients (age range 1.1-7.5 years) underwent both conventional and helical chest CT on a General Electric HiSpeed Advantage scanner at a mean study interval of 3...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02021699
更新日期:1995-01-01 00:00:00
abstract::Rib fractures are a common skeletal manifestation of non-accidental injury (NAI) in infants and young children and are generally considered to be highly specific for abuse. There are, however, relatively few descriptions of fractures involving the costochondral junctions in NAI. We present three children (two boys, on...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050436
更新日期:1998-09-01 00:00:00
abstract::There are few descriptions of the magnetic resonance (MR) appearance of hyperfunctioning adrenocortical tumours, particularly those occurring in childhood. We studied five patients, two girls and three boys, aged 6-14.3 years, presenting with clinical syndromes of adrenocortical hyperfunction. The diagnoses were Cushi...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01396204
更新日期:1996-11-01 00:00:00
abstract::A 4-month-old boy presented with persistent gross hematuria. At ultrasonography, a 3.5-cm echogenic mass with posterior shadowing and tumor vascularity was detected within the right renal pelvis. Precontrast CT showed a slightly hyperattenuating mass in the renal pelvis. At MRI the mass was heterogeneously hypointense...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-013-2855-2
更新日期:2014-05-01 00:00:00
abstract::One hundred and ten children, ages 6 days to 14 years, were investigated for vesicoureteral reflux (VUR) using ultrasound before voiding cystourethrography (VCU). Sonographically a VUR was assumed if a retrovesical dilated ureter and/or an increase of the separation of the central renal echo complex (CRC) could be det...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02343428
更新日期:1984-01-01 00:00:00
abstract::Mid-cervical kyphosis in diastrophic dysplasia (DD) with cord compression and weakness has been recognized for the last three decades. A strikingly similar situation exists in Larsen's syndrome (LS), an otherwise unrelated problem of weakness with lay joints and dislocations with typical facies. Forty patients with DD...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02010328
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Single-shot fast spin echo (SSFSE) is particularly appealing in pediatric patients because of its motion robustness. However radiofrequency energy deposition at 3 tesla forces long pauses between slices, leading to longer scans, longer breath-holds and more between-slice motion. OBJECTIVE:We sought to learn...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-014-3227-2
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Internal hernias are uncommon in children and their clinical and imaging findings have not been widely addressed. OBJECTIVE:To determine the spectrum of clinical and imaging findings of internal hernia (IH) in children and to highlight diagnostic features. MATERIALS AND METHODS:Review of clinical, imaging ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-011-2158-4
更新日期:2011-12-01 00:00:00
abstract::The authors present a case of cervical chordoma which manifested in a 5-year-old boy as a dumbbell-shaped epidural tumor without bone destruction. Both CT and MRI demonstrated tumor features suggesting this diagnosis, which was confirmed by histology. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01403709
更新日期:1996-01-01 00:00:00
abstract::Cystic fibrosis (CF) is a multiorgan disease caused by mutation of the CF transmembrane conductance regulator (CFTR) gene. Obstructive lung disease is the predominant cause of morbidity and mortality; thus, most efforts to improve outcomes are directed toward slowing or halting lung-disease progression. Current therap...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-005-1445-3
更新日期:2005-08-01 00:00:00
abstract::Hypertension due to transplant renal artery stenosis was treated with percutaneous transluminal angioplasty (PTA) in 6 children. 8 angioplasties were performed and the follow-up period varied between 3 and 66 months (average 23 months). The stenoses were located at the site of anastomosis in 4 children and distal to t...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02012999
更新日期:1992-01-01 00:00:00
abstract::Developmental stenosis of the cervical spine results in a reduction of the caliber of the cervical spinal canal that is greatest in the anteroposterior dimensions. This usually becomes symptomatic in adults when a myelopathy may result from compression of the cervical cord by small osteophytes or by hyperextension inj...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02388241
更新日期:1987-01-01 00:00:00
abstract::Rapidly involuting congenital hemangioma (RICH) is a recently recognized entity in which the vascular tumor is fully developed at birth and undergoes rapid involution. Angiographic findings in two infants with congenital hemangioma are reported and compared with a more common postnatal infantile hemangioma and a conge...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-002-0726-3
更新日期:2003-01-01 00:00:00
abstract::Necrotizing enterocolitis (NEC) is associated with considerable morbidity and mortality in infants. The diagnosis relies heavily upon radiographic and clinical features. Failure to accurately diagnose NEC is associated with a risk of complications and death, however overdiagnosis also causes both morbidity and mortali...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02395755
更新日期:1988-01-01 00:00:00
abstract::We present the MRI findings in a case of subcutaneous fat necrosis of the newborn. To our knowledge, the MRI findings of this entity have not been reported. Subcutaneous fat necrosis of the newborn is an uncommon, benign process in full-term infants. Hypercalcemia may be a potentially life-threatening complication of ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050696
更新日期:1999-10-01 00:00:00
abstract::Automatic exposure control (AEC) is particularly well-suited for pediatric CT scanning. However the importance of the localizer scan portion of exams that relies on AEC is frequently underestimated. This paper explains in detail several crucial aspects of the localizer and their effect on the subsequent cross-sectiona...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-014-3140-8
更新日期:2014-10-01 00:00:00
abstract:PURPOSE:To describe the CT features of complicated pleural tuberculosis in children and to define the use of CT in children with pleural tuberculosis. MATERIALS AND METHODS:The CT findings in 11 children with complicated pleural tuberculosis were retrospectively analysed. CT was performed to evaluate persistent pleura...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050561
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND:Traditionally, every patient with an acute scrotum needed surgical exploration for definitive exclusion of testicular torsion. OBJECTIVE:In this study, we aimed to evaluate the improved accuracy in clinical diagnosis with colour Doppler Ultrasonography (US) added to normal clinical assessment. MATERIALS AN...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-005-1411-0
更新日期:2005-06-01 00:00:00
abstract::Contrast-enhanced ultrasound (CEUS) and diffusion-weighted imaging (DWI) are safe, repeatable imaging techniques. The aim of this paper is to discuss the advantages, technical factors and possible clinical applications of these imaging tools in focal renal lesions in children. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-019-04552-9
更新日期:2020-02-01 00:00:00
abstract::A case of gastro-oesophageal intussusception was reported in 1840 by Von Rokitanski: this is rare, with only two other cases having been reported. In our patient the gastro-oesophageal intussusception followed Nissen fundoplication. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02019667
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:The classic metaphyseal lesion (CML) is highly specific for non-accidental trauma in infants. While the radiographic findings are well documented, there is little literature on the ultrasound (US) appearance. OBJECTIVE:To evaluate US findings in CMLs identified on radiographs. MATERIAL AND METHODS:This ins...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-019-04373-w
更新日期:2019-06-01 00:00:00
abstract::The anatomical anomalies that characterize septo-optic-dysplasia (deMorsier Syndrome) are variable and often subtle. We report imaging studies of nine patients with septo-optic-dysplasia which provide radiologic and ultrasonographic clues to this disorder. In addition, we propose that cerebral schizencephaly may be a ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02388642
更新日期:1989-01-01 00:00:00