Clinical assessment of synbiotics for treating chronic kidney disease: A protocol for systematic review and meta-analysis.

Abstract:

BACKGROUND:This research aims to evaluate the efficacy and safety of synbiotics for treating chronic kidney disease. METHODS:Related articles written in English were sourced from EMBASE, PubMed, Cochrane Library, and China National Knowledge Infrastructure. These articles were used in the evaluation of the effect of synbiotics for treating chronic kidney disease. The extent of the relationship was assessed by calculating the pooled risk ratio, mean differences or standardized mean difference along with the equivalent 95% confidence intervals. The risk of bias introduced through each study was considered by adopting the Cochrane Risk of Bias Tool. Suitable statistical research methods were utilized for the synthesis of the data. The RevMan 5.3 software was used to conduct all statistical analysis. RESULTS:The final results of the current study is due to be included in a peer-reviewed journal. CONCLUSION:The final remarks of the current study will be useful evidence for determining whether synbiotics is an effective and safe therapeutic method for treating chronic kidney disease. OSF REGISTRATION NUMBER:DOI 10.17605/OSF.IO/UASF4 (https://osf.io/uasf4/).

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Li XJ,Lu YY,Wang Y

doi

10.1097/MD.0000000000022993

subject

Has Abstract

pub_date

2020-12-04 00:00:00

pages

e22993

issue

49

eissn

0025-7974

issn

1536-5964

pii

00005792-202012040-00017

journal_volume

99

pub_type

杂志文章,meta分析

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