Abstract:
OBJECTIVE:To investigate the association between xerogenic medication use and tooth wear among American adults and whether this association can be explained by subjective oral dryness. METHODS:We used data from 3578 adults who participated in the National Health and Nutritional Examination Survey (NHANES). Tooth wear was clinically determined using the modified Tooth Wear Index. Information on xerogenic medication use, subjective oral dryness (amount of saliva in mouth and feeling the mouth dry when eating) and potential confounders (sociodemographic factors, dental insurance coverage, gastroesophageal reflux disease medication use and soft drinks intake) were self-reported. The associations among xerogenic medication use, subjective oral dryness and tooth wear were assessed in regression models adjusting for confounders. RESULTS:Adults taking xerogenic medication had greater odds of reporting too little amount of saliva and feeling the mouth dry when eating. In addition, participants taking one and multiple (two or more) xerogenic medications had, respectively, 1.53 (95 % CI: 1.01-2.32) and 1.44 (95 % CI: 0.62-3.33) greater odds of having tooth wear than those taking no xerogenic medications. In a regression model including all explanatory variables, the association of xerogenic medication use with tooth wear was fully attenuated whereas subjective oral dryness (amount of saliva in mouth but not feeling the mouth dry when eating) remained positively associated with prevalence of tooth wear. Similar findings were obtained with long-term use of xerogenic medication (in the past month and for three or more years). CONCLUSION:Current (last month) use of xerogenic medication was associated with the presence of tooth wear. This association was accounted for by subjective indicators of oral dryness. CLINICAL SIGNIFICANCE:Dentists should be familiar with the possible connection between patient's medical prescription and tooth wear. Changing prescriptions to non-xerogenic alternatives, whenever possible, could improve patients' oral condition. The findings also suggest that patients may recognise, through the perception of dry mouth, when medication is placing them at risk.
journal_name
J Dentjournal_title
Journal of dentistryauthors
Alwaheidi HAA,O'Toole S,Bernabé Edoi
10.1016/j.jdent.2020.103542subject
Has Abstractpub_date
2020-12-01 00:00:00pages
103542eissn
0300-5712issn
1879-176Xpii
S0300-5712(20)30290-6journal_volume
104pub_type
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journal_title:Journal of dentistry
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abstract:INTRODUCTION:Tooth surface loss (TSL) is an increasingly recognised problem. We are therefore seeing an increase in the number and complexity of in vitro studies investigating factors that modify effects at the tooth surface. AIM:The aim of this paper is to provide a narrative review that illustrates the more commonly...
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abstract::In the present study Class II resin composite restorations were placed under in vivo and in vitro conditions. For the in vivo part. Class II preparations were cut in teeth destined for extraction for orthodontic reasons. The preparations were completed with the gingival margin in enamel and restored using six differen...
journal_title:Journal of dentistry
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doi:10.1016/0300-5712(93)90026-m
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journal_title:Journal of dentistry
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更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:Untreated dental caries in children remains a public health challenge in poor communities. OBJECTIVES:This prospective controlled clinical trial investigated the effectiveness of a new anti-caries agent, Nano Silver Fluoride (NSF), applied once a year to arrest caries in children. METHODS:One hundred thirt...
journal_title:Journal of dentistry
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更新日期:2014-08-01 00:00:00
abstract:OBJECTIVES:Understanding the mechanical properties of dentine is of importance as adhesive restorative materials mainly achieve their bonding to the tooth structure through dentine. The current study measures the hardness and modulus of elasticity of primary molar dentine using an Ultra-Micro-Indentation System (UMIS),...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/s0300-5712(03)00045-9
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journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/0300-5712(95)00032-1
更新日期:1996-01-01 00:00:00
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journal_title:Journal of dentistry
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更新日期:2019-06-01 00:00:00
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journal_title:Journal of dentistry
pub_type: 杂志文章,随机对照试验
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pub_type: 杂志文章
doi:10.1016/s0300-5712(02)00067-2
更新日期:2003-01-01 00:00:00
abstract:INTRODUCTION:C. tropicalis and C. krusei have emerged as virulent species causing oral infections. Both have developed resistance to commonly prescribed azole antifungal agents. OBJECTIVE:The study aimed to determine the effect of mouth rinses containing chlorhexidine digluconate (CHX), cetylpyridinium chloride (CPC) ...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2012.04.003
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVES:The demand for restoration of root dentine defects such as cervical erosion and root caries has significantly increased recently, but there is limited information on the performance of the adhesive resins to radicular dentine. The purpose of this study was to measure the regional tensile bond strength (TBS) ...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/0300-5712(95)00102-6
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVES:The study aims at demonstrating the feasibility of a novel type of coupling-agent-free resin composite based on nano-porous fillers. METHODS:The fillers were obtained by ball-milling anodic alumina membranes. Composites were prepared with standard resin at maximum loading of 50% by weight. The resin matrix ...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2013.12.001
更新日期:2014-03-01 00:00:00
abstract::The purpose was to present a descriptive report of the clinical performance of adhesive bridges fitted in a university department of restorative dentistry. The case records of 400 consecutive adhesive bridges fitted between November 1984 and June 1989 in the School of Clinical Dentistry, Queen's University, Belfast we...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/0300-5712(91)90122-f
更新日期:1991-08-01 00:00:00
abstract::Pain following removal of impacted third molar teeth has proven to be a useful clinical model for evaluating oral analgesics. Moreover, as the underlying pathophysiology becomes elucidated the model serves as a tool for monitoring the relative contributions of different pain events, including peripheral and central se...
journal_title:Journal of dentistry
pub_type: 杂志文章,评审
doi:10.1016/0300-5712(94)90084-1
更新日期:1994-12-01 00:00:00
abstract:OBJECTIVES:This study investigated whether novel liposome formulations loaded with transforming growth factor β1 (TGF-β1) could promote the odontogenic differentiation of human dental pulp stem cells (hDPSCs) for dentine-pulp regeneration. METHODS:0-100 ng/mL of liposomal TGF-β1 was prepared using the thin-film hydrat...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2020.103501
更新日期:2020-12-01 00:00:00
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journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/s0300-5712(99)00063-9
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journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/s0300-5712(96)00051-6
更新日期:1997-09-01 00:00:00
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journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/s0300-5712(02)00011-8
更新日期:2002-05-01 00:00:00
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journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/s0300-5712(98)00019-0
更新日期:1998-07-01 00:00:00
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journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2014.04.011
更新日期:2014-08-01 00:00:00
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journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2003.12.004
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVES:The objective of the study was to determine the perceptibility and acceptability thresholds for dental ceramics using CIEDE2000 (ΔE(00)) and CIELAB (ΔE(ab)(*)) color difference formulas and a novel TSK Fuzzy Approximation. METHODS:A 13-observer panel performed independent observations of perceptibility and ...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2010.07.008
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:To detect any differences in the propensity of unstimulated and stimulated, individual whole saliva to cause in vitro staining by chlorhexidine and tea. METHODS:Unstimulated and stimulated human saliva was collected on a daily basis and used to coat optically clear acrylic specimens. Specimens were subjecte...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/s0300-5712(02)00053-2
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVES:Health condition of the gingival tissues contacting the surfaces of fixed prostheses is a result of multiple etiologic factors. The aim of the investigation discussed here was to evaluate the attachment and proliferation rate of cultured human epithelial cells on three commonly used restorative materials und...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2013.11.008
更新日期:2014-01-01 00:00:00
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journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2009.11.003
更新日期:2010-03-01 00:00:00
abstract::Replacement of pin-retained amalgam restorations is complicated by the loss of prime pin sites and remaining pin sites posing anatomical problems. Self-threading dentine pins can be removed with an ultrasonic handpiece, and the pin site reused with a large pin. Retention of replacement pins is similar to original pins...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/0300-5712(93)90109-4
更新日期:1993-10-01 00:00:00
abstract:OBJECTIVES:To determine the visual 50:50% acceptability thresholds for lightness, chroma and hue for dental ceramics using CIEDE2000(K(L):K(C):K(H)) formula, and to evaluate the formula performance using different parametric factors. METHODS:A 30-observer panel evaluated three subsets of ceramic samples: lightness sub...
journal_title:Journal of dentistry
pub_type: 杂志文章
doi:10.1016/j.jdent.2011.09.007
更新日期:2011-12-01 00:00:00