Abstract:
:After its introduction for scientific investigation in the 1950s, the cypriniform zebrafish, Danio rerio, has become a valuable model for the study of regenerative processes and mechanisms. Zebrafish exhibit epimorphic regeneration, in which a nondifferentiated cell mass formed after amputation is able to fully regenerate lost tissue such as limbs, heart muscle, brain, retina, and spinal cord. The process of limb regeneration in zebrafish comprises several stages characterized by the activation of specific signaling pathways and gene expression. We review current research on key factors in limb regeneration using zebrafish as a model.
journal_name
Zebrafishjournal_title
Zebrafishauthors
Lebedeva L,Zhumabayeva B,Gebauer T,Kisselev I,Aitasheva Zdoi
10.1089/zeb.2020.1926subject
Has Abstractpub_date
2020-12-01 00:00:00pages
359-372issue
6eissn
1545-8547issn
1557-8542journal_volume
17pub_type
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