Abstract：
:Chronic otitis media with cholesteatoma can cause erosion of the dense labyrinthine bone overlying the inner ear organs, and this labyrinthine fistula allows pressure or mass-induced motion of the underlying perilymphatic and endolymphatic compartment, evoking vestibular symptoms. While the mechanism of a positive fistula test, which is conducted by increasing or decreasing the external auditory canal pressure, has been well established, the mechanism underlying positional nystagmus in labyrinthine fistula has not been discussed yet. In the present study, we propose a new hypothesis accounting for positional nystagmus in labyrinthine fistula involving the lateral semicircular canal (LSCC), i.e., the change in intracranial cerebrospinal fluid pressure by position change is transmitted to the perilymphatic space, causing ampullopetal (excitatory) or ampullofugal (inhibitory) deflection of the LSCC cupula.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Jeong H,Lee DH,Shin JE,Kim CHdoi
10.1016/j.mehy.2020.110223subject
Has Abstractpub_date
2020-11-01 00:00:00pages
110223eissn
0306-9877issn
1532-2777pii
S0306-9877(20)32159-9journal_volume
144pub_type
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