Abstract：
BACKGROUND AND AIMS:Narrow-band imaging with magnifying endoscopy (ME-NBI) has shown advantages in the diagnosis of early gastric cancer (EGC). However, proficiency in diagnostic algorithms requires substantial expertise and experience. In this study, we aimed to develop a computer-aided diagnostic model, EGCM, to analyze and assist in the diagnosis of EGC under ME-NBI. METHODS:A total of 1777 ME-NBI images from 295 cases were collected from 3 centers. These cases were randomly divided into a training cohort (TC, n=170), an internal test cohort (ITC, n=73), and an external test cohort (ETC, n=52). EGCM based on VGG-19 with a single fully connected 2-classification layer was developed via fine-tuning and validated on all of the cohorts. Furthermore, we compared the model with 8 endoscopists with varying experience. Primary comparison measures included accuracy (ACC), the area under the receiver operating characteristic curve (AUC), sensitivity (Sn), specificity (Sp), positive predictive value (PPV), and negative predictive value (NPV). RESULTS:EGCM acquired AUCs of 0.808 in the ITC and 0.813 in the ETC. Moreover, EGCM achieved similar predictive performance to the senior endoscopists (ACC: 0.770 vs 0.755, p=0.355; Sn: 0.792 vs 0.767, p=0.183; Sp: 0.745 vs 0.742, p=0.931), but better than the junior endoscopists (ACC: 0.770 vs 0.728, p<0.05). After referring to the results of EGCM, the average diagnostic ability of the endoscopists was significantly improved in terms of accuracy, sensitivity, PPV, and NPV (p<0.05). CONCLUSION:EGCM exhibited comparable performance to senior endoscopists in the diagnosis of EGC and showed the potential value in aiding and improving the diagnosis of EGC by endoscopists.
journal_name
Gastrointest Endoscjournal_title
Gastrointestinal endoscopyauthors
Hu H,Gong L,Dong D,Zhu L,Wang M,He J,Shu L,Cai Y,Cai S,Su W,Zhong Y,Li C,Zhu Y,Fang M,Zhong L,Yang X,Zhou P,Tian Jdoi
10.1016/j.gie.2020.11.014subject
Has Abstractpub_date
2020-11-25 00:00:00eissn
0016-5107issn
1097-6779pii
S0016-5107(20)35007-0pub_type
杂志文章abstract：BACKGROUND:Hands-on endoscopy workshops are popular and valuable sources for the continuing medical education of endoscopists. Concerns, however, exist regarding clinical outcomes of procedures performed during hands-on training of ERCP. OBJECTIVE:We compared the success rates and complications between patients in the...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章,多中心研究
doi：10.1016/j.gie.2008.05.029
更新日期：2009-02-01 00:00:00
abstract：BACKGROUND:The duodenal-jejunal bypass liner (DJBL) is a new, device-based endoscopic treatment for type 2 diabetes mellitus (T2DM) and obesity. OBJECTIVE:To report serious safety events of subjects treated with the DJBL while offering a simple guideline to mitigate risk. DESIGN:Single-center observational study. SE...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2015.03.1911
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:The aim of this study was to compare use and tolerance of transnasal and transoral diagnostic endoscopy with small-diameter endoscopes in unsedated patients. METHODS:Patients being seen for diagnostic endoscopy were randomly assigned to have an unsedated transnasal or transoral procedure. Two prototype narr...
journal_title：Gastrointestinal endoscopy
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0016-5107(99)70003-9
更新日期：1999-03-01 00:00:00
abstract：BACKGROUND:A recent American Society for Gastrointestinal Endoscopy Technology Status Evaluation Report recommended comparative studies of water-aided colonoscopy methods to refine the optimal insertion technique. OBJECTIVE:Air insufflation (AI), water immersion (WI), and water exchange (WE) were compared head-to-head...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.gie.2014.07.029
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:Endoscopic submucosal dissection (ESD) with a knife is a technically demanding procedure associated with a high complication rate. The shortcoming of this method is the difficulty of fixing the knife to the target lesion. It can lead to an unexpected incision and result in major complications, such as perfor...
journal_title：Gastrointestinal endoscopy
pub_type： 临床试验,杂志文章
doi：10.1016/j.gie.2007.12.007
更新日期：2008-06-01 00:00:00
abstract：:A study of selective sedation for colonoscopy was conducted in two parts. All procedures were performed by one experienced colonoscopist. In the first phase, 41 patients received intravenous sedation before colonoscopy and were then prospectively randomized to either a "not-reversed" group, which did not receive fluma...
journal_title：Gastrointestinal endoscopy
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1994-11-01 00:00:00
abstract：:Disposable plastic biopsy forceps were compared prospectively to reusable stainless steel forceps. Thirty consecutive patients underwent a total of 249 biopsies, 124 with the disposable forceps, and 125 with reusable forceps. Biopsy locations included the esophagus, stomach, small intestine, colon, and common bile duc...
journal_title：Gastrointestinal endoscopy
pub_type： 临床试验,杂志文章
doi：10.1016/s0016-5107(90)71069-3
更新日期：1990-07-01 00:00:00
abstract：BACKGROUND:The efficient management of the endoscopy unit involves issues of scheduling. The aim of this study was to assess efficient use of an endoscopy unit and its relationship to patient waiting. METHODS:Formulas of queueing theory are applied to patient scheduling in endoscopy. The M/M/n queueing model assumes e...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1067/mge.2000.108625
更新日期：2000-10-01 00:00:00
abstract：BACKGROUND:Obesity is becoming epidemic in proportion and is leading to considerable morbidity and mortality in the community. Bariatric surgery offers one tested solution to sustained weight loss and comorbidity reduction. However, it is associated with a significant number of complications. OBJECTIVE:The objective o...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章,评审
doi：10.1016/j.gie.2009.06.025
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND AND AIMS:Pancreaticoduodenectomy is an invasive procedure, and endoscopic resection (ER) is an alternative therapy. However, details regarding the outcomes of ER are unknown, especially for superficial duodenal epithelial neoplasia (SDET). The aim of this study was to elucidate the outcomes of ER for SDET an...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2018.05.002
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:There are few data about the performance variability among endoscopists participating to nationwide or regionwide colorectal cancer screening programs. OBJECTIVE:To assess the variability of neoplasia detection rates among endoscopists participating in a regional colorectal cancer screening program based on...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2009.08.032
更新日期：2010-02-01 00:00:00
abstract：:Patients with carcinoma of the head of the pancreas will develop obstructive jaundice at some point in their course in 80% to 90% of the cases. Surgical biliary digestive anastomosis carries a high 30-day mortality (20%), and hospitalization may be prolonged for several weeks owing to postoperative morbidity. We attem...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(86)71878-6
更新日期：1986-10-01 00:00:00
abstract：BACKGROUND:A gelatinous implant containing polymethylmethacrylate (PMMA) beads is successfully used to augment the diminished thickness of the chorium in patients with skin defects and wrinkles. The aim of the present study was to determine whether submucosal injection of PMMA microspheres into the lower esophageal fol...
journal_title：Gastrointestinal endoscopy
pub_type： 临床试验,杂志文章
doi：10.1067/mge.2001.113912
更新日期：2001-04-01 00:00:00
abstract：BACKGROUND:Studies suggest that endoscopist-related factors such as colonoscopy withdrawal time are important in determining the adenoma detection rate (ADR). OBJECTIVE:To determine the importance of withdrawal technique in differentiating among endoscopists with varying ADRs. DESIGN:Prospective, multicenter study. ...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章,多中心研究
doi：10.1016/j.gie.2011.03.003
更新日期：2011-07-01 00:00:00
abstract：BACKGROUND:Initial clinical applications have shown that US elastography might be able to distinguish tissues because of their specific consistency. OBJECTIVE:(1) To investigate the feasibility of EUS elastography of the pancreas and (2) to describe elastographic patterns of the normal pancreas and the pancreas affect...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2006.12.057
更新日期：2007-06-01 00:00:00
abstract：BACKGROUND:Helicobacter Pylori is strongly associated with peptic ulcer disease. A correlation between high IgG serum antibody concentrations and a clinical diagnosis has been reported. It has been recognized that peptic ulcer disease occurs with increased frequency in cirrhosis. In this study, we attempted to establis...
journal_title：Gastrointestinal endoscopy
pub_type： 临床试验,杂志文章
doi：10.1053/ge.1999.v50.98595
更新日期：1999-09-01 00:00:00
abstract：BACKGROUND:Silastic rings are used in gastric bypass procedures for the treatment of obesity, but ring slippage may lead to gastric pouch outlet stenosis (GPOS). Conventional management has been ring removal through abdominal surgery. OBJECTIVE:To describe a novel, safe, minimally invasive, endoscopic technique for th...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.gie.2010.01.057
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:There is increasing interest in the use of propofol, an ultrashort-acting hypnotic agent, for sedation during endoscopic examinations. A protocol was developed for administration of propofol, combined with small doses of midazolam and meperidine, for endoscopic sedation under the direction of a gastroenterol...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(03)02010-8
更新日期：2003-11-01 00:00:00
abstract：BACKGROUND:Jackson Pratt (JP) drain fluid bilirubin levels may be assayed in the evaluation of possible bile leaks. Although fluid color and bilirubin level may prompt additional evaluation, there are no reference data available. OBJECTIVE:To assess the JP drain fluid-to-serum bilirubin ratio in patients with document...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2009.08.015
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND AND AIMS:Endoscopic hand-suturing (EHS) provides secure intraluminal mucosal closure and should decrease the risk of adverse events after gastric endoscopic submucosal dissection (ESD). We prospectively investigated the feasibility and safety of EHS after gastric ESD, particularly for preventing post-ESD ble...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2019.12.046
更新日期：2020-05-01 00:00:00
abstract：BACKGROUND AND AIMS:Roux-en-Y gastric bypass (RYGB) is refractory to lifestyle and pharmacotherapy measures, requiring reversal of the patient's bariatric surgery. Reversal can lead to weight regain and recrudescence of their comorbidities. Our aim was to report a multicenter experience on the endoscopic management of ...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2020.02.029
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:Unsedated esophagoscopy with ultrathin endoscopes is a valuable screening modality for Barrett's esophagus, but the stomach and the duodenum cannot be examined completely with the smallest and best tolerated of these endoscopes. There are no data as to how often disease in the stomach and the duodenum would ...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(03)02714-7
更新日期：2004-03-01 00:00:00
abstract：BACKGROUND:EUS provides excellent imaging of the gastric wall. The utility of EUS imaging in guiding the placement of a gastric pacemaker was investigated. METHODS:Fourteen patients underwent gastric pacemaker implantation for refractory gastroparesis at laparotomy. Placement of the lead into the muscle layer of the a...
journal_title：Gastrointestinal endoscopy
pub_type： 临床试验,杂志文章
doi：10.1067/mge.2002.123275
更新日期：2002-05-01 00:00:00
abstract：BACKGROUND:Complications with EUS-guided fine needle aspiration cytology (EUS-guided FNA) are rare and include perforation, infection, pancreatitis, and intraluminal bleeding. To date, the ultrasound appearance and clinical significance of perilesional bleeding during EUS-guided FNA have not been described. The aim of ...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1067/mge.2001.111391
更新日期：2001-02-01 00:00:00
abstract：OBJECTIVE:Open-access endoscopy allows physicians who are not gastroenterologists to directly schedule patients for endoscopic procedures without having them first seen in the gastrointestinal clinic. We sought to determine the prevalence of open-access endoscopy in the United States and to examine endoscopists' attitu...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(97)70204-9
更新日期：1997-07-01 00:00:00
abstract：BACKGROUND:Increasing reports suggest that endoscopic removal of benign ampullary and duodenal polyps is safe and frequently definitive; however, most reported polyps have been small in size (<3 cm). We have developed experience with endoscopic removal of increasingly large and complex polyps. PATIENTS:Fifty-one cases...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2006.06.018
更新日期：2006-12-01 00:00:00
abstract：BACKGROUND:The pharyngoesophageal segment commonly referred to as the upper esophageal sphincter (UES) generates a high-pressure zone (HPZ) between the pharynx and the esophagus. However, the exact anatomical components of the UES-HPZ remain incompletely determined. OBJECTIVE:To systematically define the US signature ...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2010.04.029
更新日期：2010-09-01 00:00:00
abstract：:A technique for expeditious and safe placement of nasoenteric feeding tubes under direct vision is described. Adult patients undergo feeding tube placement with intravenous sedation and topical anesthesia. Endoscopic tube placement requires an average of 10 min and eliminates many risks associated with blind passage. ...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(86)71882-8
更新日期：1986-10-01 00:00:00
abstract：BACKGROUND:Recent studies highlight the role of duodenal bulb biopsy in the diagnosis of celiac disease. OBJECTIVE:To determine whether a targeted duodenal bulb biopsy in addition to distal duodenal biopsies is the optimal strategy to identify villous atrophy. DESIGN:Prospective cohort study. SETTING:Tertiary-care r...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/j.gie.2012.02.025
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:The role of Helicobacter pylori in patients with cirrhosis and increased prevalence of peptic ulcers is still poorly defined. The objective is to evaluate the effect of H pylori eradication on ulcer recurrence in patients with cirrhosis. METHODS:The study was conducted at a single, tertiary, referral hospit...
journal_title：Gastrointestinal endoscopy
pub_type： 杂志文章
doi：10.1016/s0016-5107(05)01633-0
更新日期：2005-09-01 00:00:00
