Efficacy and safety of traditional Chinese medicine for erosive oral lichen planus: A protocol for systematic review and meta analysis.

Abstract:

BACKGROUND:Oral lichen planus (OLP) is a common disease among oral mucous membrane diseases. Erosive oral lichen planus (EOLP) is a type of OLP, it has a potential tendency of cancerization. There have been some randomized controlled trials (RCTs) using Traditional Chinese Medicine (TCM) to treat EOLP. No systematic review on the RCTs of TCM for EOLP has been reported, so we would propose a study protocol that aims to evaluate the evidence the efficacy and safety of TCM for treating patients with EOLP. METHODS:The following databases from the inception to June 30, 2020 electronically, including PubMed, EMBASE, Cochrane Library, Chinese National Knowledge Infrastructure, VIP, Wanfang database, China Biomedical Literature Database will be searched. RCTs that meet the pre-specified eligibility criteria will be included. RevMan software (V5.3) will be performed data synthesis following data extraction and publication risk assessment. Subgroup and sensitivity analysis will be performed according to the condition of included RCTs. The primary outcomes include visual analogy scale, laboratory immune indicators, and scores of oral lesions and signs. Additional outcomes are clinical effective rate, adverse event rate, and recurrence rate. The Grading of Recommendations Assessment, Development and Evaluation system will be used to assess the strength of the evidence. RESULTS:This study will provide a well-reported synthesis of RCTs on the efficacy and safety of TCM in the treatment of EOLP. CONCLUSION:This systematic review protocol will be helpful for providing evidence of whether TCM is an effective and safe therapeutic approach for patients with EOLP. ETHICS AND DISSEMINATION:Ethical approval is not necessary as this protocol is only for systematic review and it does not involve privacy data or conduct an animal experiment. This protocol will be disseminated by a peer-review journal or conference presentation. SYSTEMATIC REVIEW REGISTRATION:PROSPERO CRD42020172366.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

You Y,Huang X,Chen Y,You Y

doi

10.1097/MD.0000000000023375

subject

Has Abstract

pub_date

2020-11-25 00:00:00

pages

e23375

issue

48

eissn

0025-7974

issn

1536-5964

pii

00005792-202011250-00058

journal_volume

99

pub_type

杂志文章,meta分析

相关文献

MEDICINE文献大全
  • Effect of mGluR7 on proliferation of human embryonic neural stem cells.

    abstract::This study is to investigate the effect of metabotropic glutamate receptor 7 (mGluR7) on the proliferation of human embryonic neural stem cells (NSCs) and its molecular mechanism.Human embryonic NSCs were isolated. The pCMV2-GV146-GFP-mGluR7 plasmid was transfected to over-express mGluR7 while mGluR7 siRNA was transfe...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014683

    authors: Zhang J,Zhao J,Chen Y,Shi H,Huang X,Wang Y,Wang Y,Wei Y,Xue W,Han J

    更新日期:2019-03-01 00:00:00

  • Evaluation of research topic evolution in psychiatry using co-word analysis.

    abstract::With the rapid increase in the incidence of mental disorders and mental issues, psychiatry has become one of the fastest growing clinical medical disciplines. Development priorities and research foci in this field have evolved over different periods.All the articles in 10 psychiatric journals with the highest impact f...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007349

    authors: Wu Y,Jin X,Xue Y

    更新日期:2017-06-01 00:00:00

  • Keratoacanthoma and Keratoacanthoma-Like Squamous Cell Carcinoma: Similar Morphology but Different Pathogenesis.

    abstract::Differential diagnosis between keratoacanthoma (KA) and squamous cell carcinoma (SCC) is difficult due to their similarities. The mechanisms that drive their distinct biological behavior are poorly understood. To investigate whether the assessment of microvessel density (MVD) could be helpful in KA and SCC differentia...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000000934

    authors: Watanabe IC,Magalhães RF,de Moraes AM,Stelini RF,Cintra GF,Metze K,Cintra ML

    更新日期:2015-06-01 00:00:00

  • Integrated analysis of a competing endogenous RNA network reveals key lncRNAs as potential prognostic biomarkers for human bladder cancer.

    abstract::Human bladder cancer (BCa) is one of the most commonly diagnosed malignancies worldwide. It has high recurrence rates and low-grade malignancy, thus representing an important public health concern. An increasing number of studies suggest that long-noncoding RNAs (lncRNAs) play important roles in various biological pro...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011887

    authors: Zhu N,Hou J,Wu Y,Liu J,Li G,Zhao W,Ma G,Chen B,Song Y

    更新日期:2018-08-01 00:00:00

  • Association of chronic kidney disease with periprocedural myocardial injury after elective stent implantation: A single center prospective cohort study.

    abstract::Coronary artery disease (CAD) is the leading cause of mortality in patients with chronic kidney disease (CKD). Patients with CKD who undergo percutaneous coronary intervention (PCI) may have more ischemic events than patients without CKD. The aim of our study was to determine the incidence of periprocedural myocardial...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005381

    authors: Jerkic H,Letilovic T,Stipinovic M,Pocanic D,Catic J,Knotek M

    更新日期:2016-11-01 00:00:00

  • A case report of patient with severe acute cholangitis with tigecycline treatment causing coagulopathy and hypofibrinogenemia.

    abstract:RATIONALE:Tigecycline is the first member of the glycylcycline family. There are rarely reports of tigecycline causing coagulopathy and hypofibrinogenemia until now. We report a case on tigecycline-associated coagulopathy and hypofibrinogenemia and discuss the characteristics of the adverse reaction. PATIENT CONCERNS:...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000009124

    authors: Wu X,Zhao P,Dong L,Zhang X

    更新日期:2017-12-01 00:00:00

  • Discrepancy between financial disclosures of authors of clinical practice guidelines and reports by industry.

    abstract::There is a substantial effort to increase the accuracy of conflicts of interest (COI) reporting, and reduce the influence of COI between physicians and industry, especially as it relates to clinical practice guidelines.We used the newly implemented Open Payments dataset to evaluate the accuracy of COI disclosures of a...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005711

    authors: Andreatos N,Zacharioudakis IM,Zervou FN,Muhammed M,Mylonakis E

    更新日期:2017-01-01 00:00:00

  • Associations of daily sleep duration and dietary macronutrient consumption with obesity and dyslipidemia in Koreans: A cross-sectional study.

    abstract::Daily sleep duration is known to be associated with obesity and dyslipidemia.This study was performed to examine the interactions between daily sleep duration and the risks of obesity and dyslipidemia according to dietary macronutrient consumption in 14,680 Korean adults using the 5th Korean National Health and Nutrit...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005360

    authors: Doo H,Chun H,Doo M

    更新日期:2016-11-01 00:00:00

  • Recurrent Acute Liver Failure Because of Acute Hepatitis Induced by Organic Solvents: A Case Report.

    abstract::The authors present a case of recurrent acute liver failure because of occupational exposure to organic solvents. A 35-year-old man with a 3-week history of worsening jaundice and flu-like symptoms was admitted to our hospital. Viral hepatitis serology and autoimmune factors were negative. The authors considered liver...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000002445

    authors: Ito D,Tanaka T,Akamatsu N,Ito K,Hasegawa K,Sakamoto Y,Nakagawa H,Fujinaga H,Kokudo N

    更新日期:2016-01-01 00:00:00

  • Fecal microbiota transplantation therapy for Parkinson's disease: A preliminary study.

    abstract::Imbalances in the gut microbiota mediate the progression of neurodegenerative diseases such as Parkinson's disease (PD). Fecal microbiota transplantation (FMT) is currently being explored as a potential therapy for PD. The objective of this study was to assess the efficacy and safety of FMT on PD. Fifteen PD patients ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000022035

    authors: Xue LJ,Yang XZ,Tong Q,Shen P,Ma SJ,Wu SN,Zheng JL,Wang HG

    更新日期:2020-08-28 00:00:00

  • Intraocular infiltration of Philadelphia chromosome-positive acute lymphoblastic leukemia diagnosed by polymerase chain reaction from the aqueous humor: A case report.

    abstract:RATIONALE:Intraocular manifestation of hematopoietic tumors is rare and often difficult to distinguish from inflammation. We report a patient with acute lymphoblastic leukemia (ALL) who developed intraocular infiltration during the remission period. PATIENT CONCERNS:A 40-year-old man presented with hypopyon in his rig...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000018872

    authors: Hiraoka M,Ohguro H,Ikeda H,Furuya D,Takahashi S

    更新日期:2020-01-01 00:00:00

  • Therapeutic effect of enterprise stent-assisted embolization for very small ruptured intracranial aneurysms.

    abstract::Enterprise stent has been widespread used in wide-necked intracranial aneurysms and good efficacy has been achieved, but there are few reports on its applications in very small ruptured intracranial aneurysms in literatures. This study aimed to evaluate the safety and efficacy of Enterprise stent-assisted coiling embo...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007832

    authors: Qin F,Li Z,Fang X,Zhao X,Liu J,Wu D,Lai N

    更新日期:2017-08-01 00:00:00

  • Treatment of atypical gouty arthritis of the hip using total hip arthroplasty: A case report.

    abstract:RATIONALE:Gout and gouty arthritis typically involve peripheral and monoarticular joints, especially the first metatarsophalangeal joint and knees. Hip involvement in patients with gout is rare, and its diagnosis is very difficult, especially in the late stages of the disease. Total hip arthroplasty could be a surgical...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000023027

    authors: Huang Y,Huang J,Luo C,Chen L,Huang B

    更新日期:2020-10-30 00:00:00

  • A case report of infectious scleritis with corneal ulcer caused by Scedosporium aurantiacum.

    abstract:RATIONALE:Scedosporium species is rare pathogen of ocular infection. The accurate diagnosis is delaying in many cases and the clinical prognosis is poor due to its resistance to antifungal agents. This report describes a patient with infectious scleritis and corneal ulcer caused by Scedosporium auranticum infection who...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000016063

    authors: Kim H,Ahn JY,Chung IY,Seo SW,Yoo WS,Shin JH,Kim SJ

    更新日期:2019-07-01 00:00:00

  • Mutation Changes in the preC/Core Promoter in HBeAg-Positive Patients With Chronic Hepatitis B During Interferon Therapy.

    abstract::To study the changes in 3 mutations related with hepatitis B e antigen (HBeAg) in patients with HBeAg-positive chronic hepatitis B (CHB) during interferon therapy.HBeAg seroconversion is a major therapeutic milestone for patients with HBeAg-positive CHB. The precore mutation G1896A and the basal core promoter mutation...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000002657

    authors: Geng Y,Wang X,Lu X,Wu X,Xu N,Han L,Xu J

    更新日期:2016-02-01 00:00:00

  • Clinical utilization of serum- or plasma-based miRNAs as early detection biomarkers for pancreatic cancer: A meta-analysis up to now.

    abstract:BACKGROUND:Pancreatic cancer (PC) is a lethal disease, however current screening methods unable to achieve early diagnosis. Blood-based microRNAs (miRNAs) are promising molecular biomarkers for detecting PC. This meta-analysis summaries studies identifying serum- or plasma-based miRNAs dysregulated in PC patients compa...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000012132

    authors: Wei L,Yao K,Gan S,Suo Z

    更新日期:2018-08-01 00:00:00

  • Regulation of podocyte lesions in diabetic nephropathy via miR-34a in the Notch signaling pathway.

    abstract:BACKGROUND:The activation of the Notch signaling pathway has been shown to play an important role in diabetic nephropathy (DN) development. Besides, Notch-1 is a target gene in miR-34a. However, the regulation of the podocyte lesions involved in DN by miR-34a has not been identified. METHODS:This study utilized miR-34...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005050

    authors: Zhang X,Song S,Luo H

    更新日期:2016-11-01 00:00:00

  • Case report: acute demyelinating encephalomyelitis following viper bite.

    abstract::The most serious complications of the central nervous system that occur after venomous snake bite are intracranial hemorrhage and ischemic stroke.We present a rarely seen central nervous system complication, acute demyelinating encephalomyelitis, after a treated Deinagkistrodon's viper bite.On April 5, 2015, a 50-year...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005310

    authors: Xu A,Shan R,Huang D,Zhou J,Keenoo A,Qin J

    更新日期:2016-11-01 00:00:00

  • Quality of life in patients who undergo conventional or robotic-assisted total laparoscopic hysterectomy: Protocol for a systematic review of randomized controlled trials.

    abstract:BACKGROUND:Hysterectomy for benign gynecologic diseases, especially dysfunctional uterine bleeding, is one of the most common gynecologic interventions. The uterus can be removed using abdominal, vaginal, laparoscopic, or robotic-assisted laparoscopic hysterectomy. In a robotic-assisted procedure, the surgeon directs t...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000015974

    authors: Rodrigues RC,Rodrigues MRK,Freitas NO,Rudge MVC,Lima SAM

    更新日期:2019-06-01 00:00:00

  • Bee venom acupuncture for adhesive capsulitis: A protocol for systematic review and meta-analysis.

    abstract:BACKGROUND:Bee venom acupuncture has been used in treating patients with shoulder adhesive capsulitis, yet the effectiveness and safety remains unclear. Therefore, this systematic review will aim to assess the effectiveness and safety of bee venom acupuncture for shoulder adhesive capsulitis. METHODS:Electronic databa...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000019975

    authors: Chen X,Fan H,Chen J,Fan H,Wu P

    更新日期:2020-05-01 00:00:00

  • Neutropenia following intravenous immunoglobulin therapy in adult patients with immune thrombocytopenic purpura: A single center experience and literature review.

    abstract::The purpose of this study was to evaluate neutropenia following intravenous immunoglobulin (IVIG) therapy in adults with immune thrombocytopenic purpura (ITP).Our analysis included 88 patients with ITP, who received IVIG from January 2006 to March 2016, at Pusan National University Hospital in Korea. Their white blood...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000018624

    authors: Oh SB,Shin HJ

    更新日期:2020-01-01 00:00:00

  • Fibrosing mediastinitis: clinical presentation, therapeutic outcomes, and adaptive immune response.

    abstract::Fibrosing mediastinitis (FM) is a rare disorder characterized by the invasive proliferation of fibrous tissue within the mediastinum. FM frequently results in the compression of vital mediastinal structures and has been associated with substantial morbidity and mortality. Its pathogenesis remains unknown. However, in ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0b013e318237c8e6

    authors: Peikert T,Colby TV,Midthun DE,Pairolero PC,Edell ES,Schroeder DR,Specks U

    更新日期:2011-11-01 00:00:00

  • Relationship between ataxia and inferior cerebellar peduncle injury in patients with cerebral infarct.

    abstract:INTRODUCTION:The inferior cerebellar peduncle (ICP) is a major neural tract in the cerebellum and is involved in coordination of movement and proprioceptive; therefore, ICP injury can be accompanied by poor coordination of movement, including ataxia. In this study, using diffusion tensor tractography (DTT), we investig...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019344

    authors: Jang SH,Lee HD

    更新日期:2020-02-01 00:00:00

  • The spectrum of invasive pneumococcal disease at an adult tertiary care hospital in the early 21st century.

    abstract::Despite widespread pneumococcal vaccination of children and adults, invasive pneumococcal disease (IPD) remains prominent. Using our database of all Streptococcus pneumoniae infections at the Veterans Affairs Medical Center, Houston, Texas, since 2000, we reviewed cases of IPD, defined as the isolation of pneumococci ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0b013e3181f2b824

    authors: Rueda AM,Serpa JA,Matloobi M,Mushtaq M,Musher DM

    更新日期:2010-09-01 00:00:00

  • Fractional curve progression with maintenance of fusion mass in congenital scoliosis: An 18-year follow-up of a case report.

    abstract:RATIONALE:The management of congenital scoliosis concentrates on early diagnosis and proper surgical treatment before the development of severe deformities. Decision making regarding the appropriate fusion levels, proper surgical treatment, and reduction amount of kyphoscoliosis is very important but difficult in the t...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000007746

    authors: Chang DG,Yang JH,Suk SI,Suh SW,Kim JH,Lee SJ,Na KH,Lee JH

    更新日期:2017-09-01 00:00:00

  • The association between normal-range admission potassium levels in Israeli patients with acute coronary syndrome and early and late outcomes.

    abstract::Abnormal serum potassium levels are associated with an increased risk of ventricular arrhythmias and mortality in patients with acute myocardial infarction (AMI). The aim of the present study was to evaluate whether different levels of serum potassium, within the normal range, are associated with worse outcomes. The p...

    journal_title:Medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1097/MD.0000000000003778

    authors: Shlomai G,Berkovitch A,Pinchevski-Kadir S,Bornstein G,Leibowitz A,Goldenberg I,Grossman E

    更新日期:2016-06-01 00:00:00

  • A Case Report of Renal Sympathetic Denervation for the Treatment of Polymorphic Ventricular Premature Complexes: Expanding Horizons.

    abstract::Premature ventricular complexes are very common, appearing most frequently in patients with hypertension, obesity, sleep apnea, and structural heart disease. Sympathetic hyperactivity plays a critical role in the development, maintenance, and aggravation of ventricular arrhythmias. Recently, Armaganijan et al reported...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000002287

    authors: Kiuchi MG,Vitorio FP,Silva GRD,Paz LMR,Souto GLL

    更新日期:2015-12-01 00:00:00

  • Neonatal pulmonary sequestration (PS) with rhabdomyomas-like hyperplasia: A case report.

    abstract:INTRODUCTION:Pulmonary sequestration (PS) is a rare pulmonary congenital malformation characterized by disconnection with the tracheobronchial tree or the pulmonary arterial blood supply thus impeding the connection to the arterial blood supply from systemic circulation, ultimately resulting in a non-functional lung. ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000020052

    authors: Liu XM,Yuan LM,Wu YR,Zhou CJ

    更新日期:2020-05-01 00:00:00

  • Examination of pain relief effect of Goreisan for glossodynia.

    abstract:BACKGROUND:Pain in glossodynia may be severe; it may prevent patients from working, interfere with daily life activities, and necessitate a patient's visit to a medical institution for consultation and treatment. The pain may be described as persistent and burning (tingling, tingling) or stinging. Patients may complain...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021536

    authors: Ayuse T,Okayasu I,Tachi-Yoshida M,Sato J,Saisu H,Shimada M,Yamazaki Y,Imura H,Hosogaya N,Nakashima S

    更新日期:2020-08-14 00:00:00

  • Application of MR diffusion imaging for non-invasive assessment of acute kidney injury after lung transplantation.

    abstract::To assess whether MR diffusion imaging may be applied for non-invasive detection of renal changes correlating with clinical diagnosis of acute kidney injury (AKI) in patients after lung transplantation (lutx).Fifty-four patients (mean age 49.6, range 26-64 years) after lutx were enrolled in a prospective clinical stud...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000022445

    authors: Derlin K,Hellms S,Gutberlet M,Peperhove M,Jang MS,Greite R,Hartung D,Derlin T,Fegbeutel C,Tudorache I,Jüttner B,Wiese B,Lichtinghagen R,Haller H,Haverich A,Wacker F,Warnecke G,Gueler F

    更新日期:2020-12-04 00:00:00