Variations in the central corneal thickness during the menstrual cycle in Indian women.

Abstract:

Purpose:To determine the changes in central corneal thickness (CCT) during the menstrual cycle in Indian women. Methods:A prospective observational clinical study at a tertiary care center between December 2015 and December 2018. One hundred and twenty sixty women between 18 and 45 years were included. The CCT was measured using an ultrasound pachymeter at three specific timelines of the menstrual cycle: at the beginning (1st to 3rd day), during ovulation time (14th to 16th day), and at the end of the cycle (28th to 33rd day). Phases of the cycle were confirmed by the urine luteinizing hormone level. Results:The mean CCT of both eyes was 541.76 ± 4.21 μm, 559.21 ± 4.50 μm, and 544.52 ± 8.06 μm at the beginning, mid, and end of cycle, respectively. The mean CCT of the right eye was 541.68 ± 4.15 μm, 559.08 ± 4.50 μm, and 544.44 ± 8.06 μm and of the left eye was 541.84 ± 4.27 μm, 559.35 ± 4.50 μm, and 544.61 ± 8.06 μm at the beginning, mid, and end of cycle, respectively. Conclusion:The CCT value was significantly (P < 0.001) higher during ovulation compared to the beginning and end of the menstrual cycle. Our study recommends adding menstrual history in the workup of women undergoing refractive surgery as physiological variations in the CCT may result in unexpected surgical outcomes.

journal_name

Indian J Ophthalmol

authors

Mishra D,Bhushan P,Sachan S,Singh MK,Jayadev C,Kusumgar P

doi

10.4103/ijo.IJO_1207_20

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

2918-2920

issue

12

eissn

0301-4738

issn

1998-3689

pii

IndianJOphthalmol_2020_68_12_2918_301207

journal_volume

68

pub_type

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