JavaCyte, a novel open-source tool for automated quantification of key hallmarks of cardiac structural remodeling.

abstract：:The negatively-charged nitrogen vacancy (NV(-)) center in diamond is of great interest for quantum information processing and quantum key distribution applications due to its highly desirable long coherence times at room temperature. One of the challenges for their use in these applications involves the requirement to...

journal_title：Scientific reports

authors： Khalid A,Chung K,Rajasekharan R,Lau DW,Karle TJ,Gibson BC,Tomljenovic-Hanic S

更新日期：2015-06-25 00:00:00

abstract：:Intermediate level radioactive waste (ILW) generally contains a heterogeneous range of organic and inorganic materials, of which some are encapsulated in cement. Of particular concern are cellulosic waste items, which will chemically degrade under the conditions predicted during waste disposal, forming significant qua...

journal_title：Scientific reports

authors： Kuippers G,Boothman C,Bagshaw H,Ward M,Beard R,Bryan N,Lloyd JR

更新日期：2018-06-08 00:00:00

abstract：:Amyloid-β (Aβ) deposition is known to starts decades before the onset of clinical symptoms of Alzheimer's disease (AD), however, the detailed pathophysiological processes underlying this preclinical period are not well understood. This study aimed to investigate functional network alterations in cognitively intact eld...

journal_title：Scientific reports

authors： Nakamura A,Cuesta P,Kato T,Arahata Y,Iwata K,Yamagishi M,Kuratsubo I,Kato K,Bundo M,Diers K,Fernández A,Maestú F,Ito K

更新日期：2017-07-26 00:00:00

abstract：:In the epoch of the Anthropocene change, complexity, and uncertainty create a demand for new systems of water management and governance. One such management model that is rapidly gaining traction amongst both scholars and practitioners is the concept of water resilience. Although increasing attention has been paid to ...

journal_title：Scientific reports

authors： Baird J,Dale G,Farhad S

更新日期：2020-04-06 00:00:00

abstract：:To meet the demand for detection of foreign genes in genetically modified (GM) sugarcane necessary for regulation of gene technology, an efficient method with high specificity and rapidity was developed for the cry1Ac gene, based on loop-mediated isothermal amplification (LAMP). A set of four primers was designed usin...

journal_title：Scientific reports

authors： Zhou D,Guo J,Xu L,Gao S,Lin Q,Wu Q,Wu L,Que Y

更新日期：2014-05-09 00:00:00

abstract：:Sepsis is associated with thrombocytopenia and microvascular thrombosis. Studies have described platelets implication in this pathology but their kinetics of activation and behavior remain poorly known. We show in a mouse model of peritonitis, the appearance of platelet-rich thrombi in organ microvessels and organ dam...

journal_title：Scientific reports

authors： Vardon Bounes F,Mémier V,Marcaud M,Jacquemin A,Hamzeh-Cognasse H,Garcia C,Series J,Sié P,Minville V,Gratacap MP,Payrastre B

更新日期：2018-09-10 00:00:00

abstract：:The TREX complex mediates the passage of bulk cellular mRNA export to the nuclear export factor TAP/NXF1 via the export adaptors ALYREF or UIF, which appear to act in a redundant manner. TREX complex recruitment to nascent RNA is coupled with 5' capping, splicing and polyadenylation. Therefore to facilitate expression...

journal_title：Scientific reports

authors： Tunnicliffe RB,Tian X,Storer J,Sandri-Goldin RM,Golovanov AP

更新日期：2018-10-09 00:00:00

abstract：:Silicon nanowires (SiNWs) attached to a wafer substrate are converted to inversely tapered silicon nanocones (SiNCs). After excitation with visible light, individual SiNCs show a 200-fold enhanced integral band-to-band luminescence as compared to a straight SiNW reference. Furthermore, the reverse taper is responsible...

journal_title：Scientific reports

authors： Schmitt SW,Sarau G,Christiansen S

更新日期：2015-11-26 00:00:00

abstract：:Pelvic recurrence of colorectal cancer is a crucial problem because radical surgery can lead to excessive invasion. Novel therapeutic strategies are required instead of surgery. However, there are few suitable models because of the difficulty in transplanting and observing tumors in the pelvis. We have established an ...

journal_title：Scientific reports

authors： Yamamoto M,Taniguchi K,Masubuchi S,Tominaga T,Inomata Y,Miyamoto A,Ishizuka TA,Murakami T,Osumi W,Hamamoto H,Tanaka K,Okuda J,Uchiyama K

更新日期：2019-12-23 00:00:00

abstract：:The mechanisms contributing to collective attention in humans remain unclear. Research indicates that pedestrians utilise the gaze direction of others nearby to acquire environmentally relevant information, but it is not known which, if any, additional social cues influence this transmission. Extending upon previous f...

journal_title：Scientific reports

authors： Gallup AC,Chong A,Kacelnik A,Krebs JR,Couzin ID

更新日期：2014-07-23 00:00:00

abstract：:Light, as the energy source in photosynthesis, is essential for plant growth and development. Extended darkness causes dramatic gene expression changes. In this study, we applied DNase-seq (DNase I hypersensitive site sequencing) to study changes of chromatin accessibility in euchromatic and heterochromatic regions un...

journal_title：Scientific reports

authors： Liu Y,Zhang W,Zhang K,You Q,Yan H,Jiao Y,Jiang J,Xu W,Su Z

更新日期：2017-06-22 00:00:00

abstract：:Neurovascular unit (NVU) is a basic unit in the brain, including neurons, glial cells, blood vessels and extracellular matrix. This concept implies the importance of a three-dimensional (3D) culture model including these cell types for investigating brain functions. However, little is known about the construction of a...

journal_title：Scientific reports

authors： Uwamori H,Higuchi T,Arai K,Sudo R

更新日期：2017-12-11 00:00:00

abstract：:Phototherapy was introduced in the early 1950's, and is the primary treatment of severe neonatal jaundice or Crigler-Najjar syndrome. Nevertheless, the potential biological effects of the products generated from the photodegradation of bilirubin during phototherapy remain unknown. This is very relevant in light of rec...

journal_title：Scientific reports

authors： Jašprová J,Dal Ben M,Hurný D,Hwang S,Žížalová K,Kotek J,Wong RJ,Stevenson DK,Gazzin S,Tiribelli C,Vítek L

更新日期：2018-05-10 00:00:00

abstract：:Lung cancer is the leading cause of death among all malignancies due to rapid tumor progression and relapse; however, the underlying molecular mechanisms of tumor progression are unclear. In the present study, we identified ANKRD22 as a novel tumor-associated gene in non-small cell lung cancer (NSCLC). According to th...

journal_title：Scientific reports

authors： Yin J,Fu W,Dai L,Jiang Z,Liao H,Chen W,Pan L,Zhao J

更新日期：2017-06-30 00:00:00

abstract：:Viruses exploit host factors and environment for their efficient replication. The virus-host interaction mechanisms for achieving an optimal hepatitis B virus (HBV) replication have been largely unknown. Here, a single cell cloning revealed that HepAD38 cells, a widely-used HBV-inducible cell line, contain cell clones...

journal_title：Scientific reports

authors： Iwamoto M,Cai D,Sugiyama M,Suzuki R,Aizaki H,Ryo A,Ohtani N,Tanaka Y,Mizokami M,Wakita T,Guo H,Watashi K

更新日期：2017-09-06 00:00:00

abstract：:NbP is a recently realized Weyl semimetal (WSM), hosting Weyl points through which conduction and valence bands cross linearly in the bulk and exotic Fermi arcs appear. The most intriguing transport phenomenon of a WSM is the chiral anomaly-induced negative magnetoresistance (NMR) in parallel electric and magnetic fie...

journal_title：Scientific reports

authors： Niemann AC,Gooth J,Wu SC,Bäßler S,Sergelius P,Hühne R,Rellinghaus B,Shekhar C,Süß V,Schmidt M,Felser C,Yan B,Nielsch K

更新日期：2017-03-06 00:00:00

abstract：:Because of inadequate nutrient and water supply, soils are often unproductive in Northwest China. We studied the effects of manure application at low (LM 7.5  t ha(-1)), medium (MM 15 t ha(-1)), and high (HM 22.5 t ha(-1)) rates combined with fixed levels of chemical fertilizers on maize growth and rainfall use effici...

journal_title：Scientific reports

authors： Wang X,Jia Z,Liang L,Yang B,Ding R,Nie J,Wang J

更新日期：2016-02-12 00:00:00

abstract：:Herein, we propose a new strategy of maskless lithographic approach to fabricate micro/nano-porous structures by phase separation of polystyrene (PS)/Polyethylene glycol (PEG) immiscible polymer blend. Its simple process only involves a spin coating of polymer blend followed by a development with deionized water rinse...

journal_title：Scientific reports

authors： Guo X,Liu L,Zhuang Z,Chen X,Ni M,Li Y,Cui Y,Zhan P,Yuan C,Ge H,Wang Z,Chen Y

更新日期：2015-10-30 00:00:00

abstract：:Taste receptors on enteroendocrine cells sense nutrients and transmit signals that control gut hormone release. This study aimed to investigate the amino acid (AA) sensing mechanisms of the ghrelin cell in a gastric ghrelinoma cell line, tissue segments and mice. Peptone and specific classes of amino acids stimulate g...

journal_title：Scientific reports

authors： Vancleef L,Van Den Broeck T,Thijs T,Steensels S,Briand L,Tack J,Depoortere I

更新日期：2015-10-29 00:00:00

abstract：:We report low-temperature solution-processed p-CuO nanorods (NRs)/n-ZnO NRs heterojunction light emitting diode (LED), exploiting the native point defects of ZnO NRs. ZnO NRs were synthesized at 90 °C by using hydrothermal method while CuO NRs were synthesized at 100 °C by using microwave reaction system. The electric...

journal_title：Scientific reports

authors： Biswas P,Baek SD,Lee SH,Park JH,Lee SJ,Lee TI,Myoung JM

更新日期：2015-12-09 00:00:00

abstract：:New plant protection strategies focus on minimizing chemical pesticide use and increasing their compatibility with biological control agents. The objective was to evaluate the side-effects of glyphosate, diflubenzuron, malathion, tebuconazole and triflumuron (at 720, 45, 400, 150 and 20 g ai ha-1, respectively), pesti...

journal_title：Scientific reports

authors： Cruz RA,Zanuncio JC,Lacerda MC,Wilcken CF,Fernandes FL,Tavares WS,Soares MA,Sediyama CS

更新日期：2017-08-30 00:00:00

abstract：:Ornamental plants represent a major pathway of invasion for alien pests worldwide. Commodity risk analyses are carried out to assess the risk posed by a new trade in a commodity, but they are restricted by our limited knowledge of the pests carried by traded plants. We used the sentinel nursery technique to identify i...

journal_title：Scientific reports

authors： Kenis M,Li H,Fan JT,Courtial B,Auger-Rozenberg MA,Yart A,Eschen R,Roques A

更新日期：2018-07-25 00:00:00

abstract：:Kinase inhibitors are often used as cancer targeting agents for their ability to prevent the activation of cell growth and proliferation signals. Cardiotoxic effects have been identified for some marketed kinase inhibitors that were not detected during clinical trials. We hypothesize that more predictive cardiac funct...

journal_title：Scientific reports

authors： Conant G,Ahadian S,Zhao Y,Radisic M

更新日期：2017-09-18 00:00:00

abstract：:Profiling immune repertoires by high throughput sequencing enhances our understanding of immune system complexity and immune-related diseases in humans. Previously, cloning and Sanger sequencing identified limited numbers of T cell receptor (TCR) nucleotide sequences in rhesus monkeys, thus their full immune repertoir...

journal_title：Scientific reports

authors： Li Z,Liu G,Tong Y,Zhang M,Xu Y,Qin L,Wang Z,Chen X,He J

更新日期：2015-05-11 00:00:00

abstract：:Droplet microfluidics has attracted significant interests in functional microcapsule synthesis, pharmaceuticals, fine chemicals, cosmetics and biomedical research. The low variability of performing chemical reactions inside droplets could benefit from improved homogeneity and reproducibility. Therefore, accurate and c...

journal_title：Scientific reports

authors： Zhu X,Su S,Fu M,Liu J,Zhu L,Yang W,Jing G,Guo Y

更新日期：2018-07-02 00:00:00

abstract：:Zika virus infection and dengue and chikungunya fevers are emerging viral diseases that have become public health threats. Their aetiologic agents are transmitted by the bite of genus Aedes mosquitoes. Without effective therapies or vaccines, vector control is the main strategy for preventing the spread of these disea...

journal_title：Scientific reports

authors： Lopez SBG,Guimarães-Ribeiro V,Rodriguez JVG,Dorand FAPS,Salles TS,Sá-Guimarães TE,Alvarenga ESL,Melo ACA,Almeida RV,Moreira MF

更新日期：2019-03-11 00:00:00

abstract：:Human epididymis protein 4 (HE4) has been used as a biomarker of endometrial cancer (EC) in clinical practice. However, there remains a lack of systemic research on the critical values of HE4 for diagnosing different clinical stages and pathological types of EC. This study investigated the accuracy of human epididymis...

journal_title：Scientific reports

authors： Liu J,Han L,Jiao Z

更新日期：2021-01-12 00:00:00

abstract：:The widespread use of electric light and electronic devices has resulted in an excessive exposure to light during the late-evening and at night. This late light exposure acutely suppresses melatonin and sleepiness and delays the circadian clock. Here we investigate whether the acute effects of late-evening light expos...

journal_title：Scientific reports

authors： Te Kulve M,Schlangen LJM,van Marken Lichtenbelt WD

更新日期：2019-11-05 00:00:00

abstract：:HOX proteins interact with PBX and MEIS cofactors, which belong to the TALE-class of homeodomain (HD)-containing transcription factors. Although the formation of HOX-PBX complexes depends on a unique conserved HOX motif called hexapeptide (HX), the additional presence of MEIS induces a remodeling of the interaction, l...

journal_title：Scientific reports

authors： Dard A,Jia Y,Reboulet J,Bleicher F,Lavau C,Merabet S

更新日期：2019-04-05 00:00:00

abstract：:Granule cells at the input layer of the cerebellum comprise over half the neurons in the human brain and are thought to be critical for learning. However, little is known about granule neuron signaling at the population scale during behavior. We used calcium imaging in awake zebrafish during optokinetic behavior to re...

journal_title：Scientific reports

authors： Sylvester SJG,Lee MM,Ramirez AD,Lim S,Goldman MS,Aksay ERF

更新日期：2017-11-24 00:00:00