The attentive focus on T cell-mediated autoimmune pathogenesis of psoriasis, lichen planus and vitiligo.

abstract：:The fluid-phase terminal complement complex (TCC), consisting of the components C5b, C6, C7, C8, C9, and the S-protein, has recently been detected in normal human plasma by using antibodies against native terminal complement components. Increased amounts of TCC were then found in several patients with in vivo activati...

journal_title：Scandinavian journal of immunology

authors： Mollnes TE,Lea T,Frøland SS,Harboe M

更新日期：1985-08-01 00:00:00

abstract：:Chlamydia pneumoniae initiates infection in humans via the mucosal epithelia of the respiratory tract; therefore, immunity at this mucosal site is believed to be important to control infection with this pathogen. We compared the protective capacity of immunization in mice with two C. pneumoniae antigens, namely the ma...

journal_title：Scandinavian journal of immunology

authors： Rodríguez A,Rottenberg M,Tjärnlund A,Fernández C

更新日期：2006-03-01 00:00:00

abstract：:Phagocytosis of Staphylococcus aureus by human polymorphonuclear leucocytes (PMN) on the surface of endothelial cells is accompanied by adherence of the PMN to the endothelial surface and detachment of the endothelial cells from the culture monolayer. We studied the role of the leucocyte adherence-related glycoprotein...

journal_title：Scandinavian journal of immunology

authors： Vandenbroucke-Grauls CM,Thijssen HM,Tetteroo PA,Rozemuller E,Verhoef J

更新日期：1989-07-01 00:00:00

abstract：:Understanding the specificity of antibody response to Neisseria meningitidis serogroup B (Men B) is a key requirement for the development of an effective vaccine. This study was designed to investigate the antigen specificity of murine IgG1 and IgG2b antibodies induced by different primary immunization schedules and t...

journal_title：Scandinavian journal of immunology

authors： Silva Junior FC,Gioia CA,Oliveira JM,Cruz SC,Frasch CE,Milagres LG

更新日期：2007-01-01 00:00:00

abstract：:The mixed lymphocyte culture (MLC) response of lymphocytes from CBA mice against C3H cells was studied after injection of spleen cells from C3H mice or C3H hybrids. Intravenous infusion of C3H cells resulted in a strongly suppressed specific MLC response, but this was not the case when cells from H-2-incompatible hybr...

journal_title：Scandinavian journal of immunology

authors： Lilliehöök B,Jacobsson H,Blomgren H

更新日期：1975-01-01 00:00:00

abstract：:The stimulation of peripheral blood mononuclear cells by purified autologous and/or allogeneic monoclonal IgG was studied in five patients with multiple myeloma (MM), nine patients with monoclonal gammopathy of undetermined significance (MGUS) and six healthy individuals. Single cells secreting IFN-gamma or IL-2 were ...

journal_title：Scandinavian journal of immunology

authors： Yi Q,Bergenbrant S,Osterborg A,Osby E,Ostman R,Björkholm M,Holm G,Lefvert AK

更新日期：1993-12-01 00:00:00

abstract：:The procoagulant activities of non-elicited mouse monocytes/macrophages from four anatomical localizations were compared. These cell populations were further examined for their ability to increase their procoagulant activity on exposure to endotoxin or phytohaemagglutinin (PHA). Peritoneal macrophages exhibited the hi...

journal_title：Scandinavian journal of immunology

authors： Lyberg T,Amlie E,Kaplun A,Prydz H

更新日期：1983-09-01 00:00:00

abstract：:CD8+ T cells are thought to play an important role in protective immunity against tuberculosis. We report the identification of three peptides derived from Rv1818c, Rv3812 and Rv3018c proteins of Mycobacterium tuberculosis that bound to HLA-A*0201 molecules and their ability to induce in vitro T-cell response in perip...

journal_title：Scandinavian journal of immunology

authors： Chaitra MG,Shaila MS,Chandra NR,Nayak R

更新日期：2008-04-01 00:00:00

abstract：:Pretreatment with D-Penicillamine of rat peritoneal macrophages markedly influences their ability to modulate Concanavalin A stimulated [3H]thymidine incorporation in non-adherent rat lymph node cells. Untreated macrophages added in high numbers to the lymphocytes (ratio lymphocytes/macrophage 7.5 : 1) depress their [...

journal_title：Scandinavian journal of immunology

authors： Binderup L,Bramm E,Arrigoni-Martelli E

更新日期：1978-04-01 00:00:00

abstract：:The lymphokine secretion patterns of seven independent 91-101.lambda 2(315)/I-Ed specific, CD4+ T-cell clones have been investigated. Six of the clones are of the Th1 type as they secrete IL2 and IFN gamma, but not IL4. Some of these six Th1 clones produce TNF alpha/beta, and some produce minor amounts of IL5 and IL6....

journal_title：Scandinavian journal of immunology

authors： Lauritzsen GF,Bogen B

更新日期：1991-06-01 00:00:00

abstract：:During the germinal centre reaction (GC), B cells with non-functional or self-reactive antigen receptors are negatively selected by apoptosis to generate B cell repertoire with appropriate antigen specificities. We studied the molecular mechanism of Fas/CD95- and B cell receptor (BCR)-induced apoptosis to shed light o...

journal_title：Scandinavian journal of immunology

authors： Eeva J,Nuutinen U,Ropponen A,Mättö M,Eray M,Pellinen R,Wahlfors J,Pelkonen J

更新日期：2009-12-01 00:00:00

abstract：:Autologous and allogeneic mixed lymphocyte cultures (AMC and MLC) were assayed for blastogenesis, generation of cytotoxic potential, and the effect of interferon (IFN-alpha) on these features. The cells of the mixed cultures lysed K562, Daudi, and autologous and allogeneic phytohaemagglutinin blasts. Stimulator-specif...

journal_title：Scandinavian journal of immunology

authors： Argov S,Klein E

更新日期：1983-03-01 00:00:00

abstract：:TNF-alpha production has a central role in the development and progression of Pseudomonas aeruginosa septic shock. We have previously shown that P. aeruginosa slime-glycolipoprotein (slime-GLP) is the most potent stimulant compared to P. aeruginosa lipopolysaccharide (LPS), for TNF-alpha production and NF-kB activatio...

journal_title：Scandinavian journal of immunology

authors： Lagoumintzis G,Xaplanteri P,Dimitracopoulos G,Paliogianni F

更新日期：2008-02-01 00:00:00

abstract：:This study is to investigate the regulation of Toll-like receptor (TLR) expression in systemic immune reactions in different arthritis rat models, which will provide evidence to understand the mechanisms of rheumatoid arthritis further. Arthritis-susceptible DA rats were used to induce arthritis by pristane or collage...

journal_title：Scandinavian journal of immunology

authors： Zhu W,Meng L,Jiang C,Xu J,Wang B,Han Y,Lu S

更新日期：2012-09-01 00:00:00

abstract：:When the virus dose is increased from 10(2) (low dose) to 10(4) LD50 (high dose) a fatal lymphocytic choriomeningitis virus (LCMV) infection is changed into a subclinical one, and a selective virus-specific delayed-type hypersensitivity (DTH) unresponsiveness is induced, while the cytotoxic T-cell response remains ess...

journal_title：Scandinavian journal of immunology

authors： Marker O,Thomsen AR

更新日期：1986-08-01 00:00:00

abstract：:Two cytokines, interferon (IFN) and interleukin 2 (IL-2), activate murine natural killer (NK) cells in vitro. Together both factors synergize considerably. Antibody against IFN eliminates the response of NK cells to IFN as well as to IL-2, whereas antibody against IL-2 blocks the effect of IL-2 but not of IFN. These f...

journal_title：Scandinavian journal of immunology

authors： Chun M,Krim M,Granelli-Piperno A,Hirst JA,Hoffmann MK

更新日期：1985-10-01 00:00:00

abstract：:Antibodies to interleukin-2 (IL-2) have been reported in the sera of patients under therapies involving this cytokine and in the sera of patients infected with human immunodeficiency virus (HIV). Our study proves that auto-antibodies to IL-2 are present also, at a lower titre, in healthy individuals. These antibodies ...

journal_title：Scandinavian journal of immunology

authors： Tiberio L,Caruso A,Pozzi A,Rivoltini L,Morelli D,Monti E,Balsari A

更新日期：1993-11-01 00:00:00

abstract：:Previous investigations have indicated that C3H X CBA hybrid lymphocytes can neutralize lymphocytes which are reactive against the C3H-determined Mls antigen when injected into the H-2-compatible strain CBA. In this study we have inoculated C3H X CBA hybrids with CBA spleen cells and 2 weeks later lethally irradiated ...

journal_title：Scandinavian journal of immunology

authors： Lilliehöök B,Blomgren H

更新日期：1978-01-01 00:00:00

abstract：:Assessment of cytokine expression has become crucial to understand host responses to infections as well as autoimmunity. Several approaches including Northern blot, RNase protection assay and enzyme-linked immunosorbent assay have been used for this purpose, but they are time consuming, labour intense, and relatively ...

journal_title：Scandinavian journal of immunology

authors： Ramos-Payán R,Aguilar-Medina M,Estrada-Parra S,González-Y-Merchand JA,Favila-Castillo L,Monroy-Ostria A,Estrada-Garcia IC

更新日期：2003-05-01 00:00:00

abstract：:The production of type 1 (interferon or IFN-gamma) and type 2 (interleukin or IL-4 and IL-10) cytokines by mitogen-stimulated peripheral blood mononuclear cells (PBMCs) obtained from asymptomatic human immunodeficiency virus-seropositive (HIV+) patients untreated with any antiviral, antibacterial or antimycotic drugs,...

journal_title：Scandinavian journal of immunology

authors： Canaris AD,Caruso A,Licenziati S,Cantalamessa A,De Francesco MA,Fallacara F,Fiorentini S,Dima F,Martinelli F,Manca N,Balsari A,Turano A

更新日期：1998-02-01 00:00:00

abstract：:The lectins from Datura stramonium, Lycopersicon esculentum, and Solanum tuberosum are structurally related and possess a similar carbohydrate specificity, yet the Datura lectin is mitogenic for human lymphocytes while the other two are not. However, the Datura lectin was found to antagonize blast transformation induc...

journal_title：Scandinavian journal of immunology

authors： McCurrach PM,Kilpatrick DC

更新日期：1988-01-01 00:00:00

abstract：:Passive antibody can both suppress and augment immune responses. Until recently, there was virtual unanimity on the importance of the interaction of the Fc portion of modulating antibody with Fc-receptors (Fc-signalling), especially in experiments involving the suppression by antibody. Experiments reported in the last...

journal_title：Scandinavian journal of immunology

authors： Sinclair NR

更新日期：2001-04-01 00:00:00

abstract：:Human lymphocytes were cultured under different conditions to determine the effects of technical variations on the response to pokeweed mitogen (PWM) and Staphylococcus aureus as measured by (a) quantitation of immunoglobulins (Ig) in the culture supernatants and (b) enumeration of Ig-secreting cells (ISC) by a revers...

journal_title：Scandinavian journal of immunology

authors： Munoz J,Pryjma J,Fudenberg HH,Virella G

更新日期：1980-01-01 00:00:00

abstract：:Foot-and-mouth disease (FMD) caused by FMD virus (FMDV) is a major health and economic problem in the farming industry. Vaccination of livestock against this highly infectious viral disease is crucial, and inactivated FMD vaccine has been effective at controlling infection. However, accumulated data show that the inac...

journal_title：Scandinavian journal of immunology

authors： Kang J,Zuo Y,Guo Q,Wang H,Liu Q,Liu Q,Xia G,Kang Y

更新日期：2015-11-01 00:00:00

abstract：:Cockroaches have been identified as one of the major indoor allergens inducing perennial rhinitis and asthma. Per a 1s are a group of the major allergens from American cockroach. Although Per a 1s are major allergens from American cockroach, factors contributing to the allergenicity of Per a 1s are still poorly define...

journal_title：Scandinavian journal of immunology

authors： He S,Zhang Z,Zhang H,Wei J,Yang L,Yang H,Sun W,Zeng X,Yang P

更新日期：2011-09-01 00:00:00

abstract：:To delineate accurately the IgG subclass distribution of thyroid auto-antibodies, sera from nine patients with Hashimoto's thyroiditis were fractionated into IgG subclasses by complete depletion of the other IgG subclasses on affinity columns. All IgG subclass fractions contained thyroglobulin and microsomal (or thyro...

journal_title：Scandinavian journal of immunology

authors： Weetman AP,Black CM,Cohen SB,Tomlinson R,Banga JP,Reimer CB

更新日期：1989-07-01 00:00:00

abstract：:Histoplasma capsulatum is a fungus found intracellularly in neutrophils and peripheral blood mononuclear cells (PBMCs), suggesting that it is capable of evading damage and survives inside these cells. In this study, we report that neutrophils from H. capsulatum-infected mice, and human neutrophils and mononuclear cell...

journal_title：Scandinavian journal of immunology

authors： Medeiros AI,Bonato VL,Malheiro A,Dias AR,Silva CL,Faccioli LH

更新日期：2002-10-01 00:00:00

abstract：:The immune response of adult BALB/c mice against the bacterial antigen dextran B1355S (Dex) is well characterized as thymus independent (TI type 2) and Igha linked. The antisera consist of mainly IgM/lambda antibodies directed against the alpha(1-->3) glucosidic linkage. This study describes the immune response agains...

journal_title：Scandinavian journal of immunology

authors： Willers J,Weiler E,Kolb C

更新日期：1995-09-01 00:00:00

abstract：:Proteins secreted by Mycobacterium tuberculosis are targets of host immune responses and as such are investigated for vaccine and immunodiagnostics development. Computer-driven searches of the M. tuberculosis H37Rv genome had previously identified 45 novel secreted proteins. Here, we report the characterization of the...

journal_title：Scandinavian journal of immunology

authors： Ben Amor Y,Shashkina E,Johnson S,Bifani PJ,Kurepina N,Kreiswirth B,Bhattacharya S,Spencer J,Rendon A,Catanzaro A,Gennaro ML

更新日期：2005-02-01 00:00:00

abstract：:Direct contact between lymphokine-activated killer (LAK) cells and tumour cells is believed to be imperative for initiating tumour cell lysis in vitro as well as in vivo. In order to optimize adoptive immunotherapy (AIT) it is therefore desirable to identify the LAK cell subtype, which ensures maximal infiltration of ...

journal_title：Scandinavian journal of immunology

authors： Kjaergaard J,Hokland M,Nannmark U,Hokland P,Basse P

更新日期：1998-06-01 00:00:00