The effects of acute hyponatraemia on bone turnover in patients with subarachnoid haemorrhage: A preliminary report.

abstract：BACKGROUND:Type 1 diabetes mellitus (T1DM) is associated with skeletal fragility. While previous meta-analyses have demonstrated an increased risk of fracture in individuals with T1DM, little is known about fracture risk in T1DM, in the absence of age-related confounders. AIMS:To determine the risk of fracture in youn...

journal_title：Clinical endocrinology

authors： Thong EP,Herath M,Weber DR,Ranasinha S,Ebeling PR,Milat F,Teede H

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:Centripetal obesity is associated with systemic low-grade inflammation and an increased cardiovascular risk. Patients in long-term remission of Cushing's syndrome (CS) report persisting abdominal fat accumulation. However, this has previously not been adequately objectified. Therefore, we investigated the adi...

journal_title：Clinical endocrinology

authors： Wagenmakers M,Roerink S,Gil L,Plantinga T,Smit J,Netea-Maier R,Hermus A

更新日期：2015-02-01 00:00:00

abstract：:A new model has been established for the perfused in situ rat lung. During perfusion with glucose at 4 mmol/l, physiological concentrations of insulin (50 mu/l) caused an initial 1.5 fold increase in lactate production; the increase being sustained at 30% for the 4 h of perfusion. The observation that the lung respond...

journal_title：Clinical endocrinology

authors： Stubbs WA,Morgan I,Lloyd B,Alberti KG

更新日期：1977-09-01 00:00:00

abstract：OBJECTIVE:The autoimmune thyroid diseases, Graves disease and autoimmune hypothyroidism, result from a complex interaction between genetic, environmental and endogenous factors. The genetic loci conferring susceptibility remain unclear. A recent report has demonstrated an association between a microsatellite polymorphi...

journal_title：Clinical endocrinology

authors： Kotsa K,Watson PF,Weetman AP

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:The prevalence of clinically silent corticotroph macroadenomas is unknown. Our aim was to determine the prevalence of clinically silent corticotroph macroadenomas among all pituitary macroadenomas. DESIGN:Patients scheduled to have transsphenoidal surgery for any sellar mass were prospectively evaluated clin...

journal_title：Clinical endocrinology

authors： Guttenberg KB,Mayson SE,Sawan C,Kharlip J,Lee JY,Martinez-Lage M,Loevner LA,Ewanichak J,Grady MS,Snyder PJ

更新日期：2016-12-01 00:00:00

abstract：:A new variant albumin with increased affinities for iodothyronines has been identified. A euthyroid woman had raised total serum concentrations of T4 (155 nmol/l), T3 (3.0 nmol/l) and rT3 (700 pmol/l) but normal levels of all three iodothyronine-binding proteins. The affinity constant for T3 binding to the albumin was...

journal_title：Clinical endocrinology

authors： Lalloz MR,Byfield PG,Himsworth RL

更新日期：1985-04-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of hyperprolactinaemia and its treatment with dopamine-agonists on bone mass and turnover in adolescent patients compared to adults. PATIENTS:Forty patients with hyperprolactinaemia (20 with disease onset during adolescence and 20 during adulthood) and 40 healthy control subjects. DES...

journal_title：Clinical endocrinology

authors： Colao A,Di Somma C,Loche S,Di Sarno A,Klain M,Pivonello R,Pietrosante M,Salvatore M,Lombardi G

更新日期：2000-03-01 00:00:00

abstract：:Serum thyroxine was consistently unmeasurable by radioimmunoassay in an elderly patient with myxoedema after successful treatment with oral thyroxine. Abnormal binding of thyroxine was suspected and shown to be due to the presence in serum of antibodies of the IgG variety. The characteristics of these antibodies with ...

journal_title：Clinical endocrinology

authors： Pearce CJ,Byfield PG,Edmonds CJ,Lalloz MR,Himsworth RL

更新日期：1981-07-01 00:00:00

abstract：BACKGROUND:Adrenal vein sampling (AVS) failure is mainly due to right adrenal vein unavailability. Multinomial regression modelling (MRM) and left adrenal vein-to-peripheral vein ratio (LAV/PV) were proposed to predict the lateralization index without the right AVS. OBJECTIVE:To assess external validity of MRM and LAV...

journal_title：Clinical endocrinology

authors： Bouchard-Bellavance R,Perrault F,Soulez G,Chagnon M,Kline GA,Bourdeau I,Lacroix A,So B,Therasse E

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Iodide (I(-)) is crucial for foetal thyroid function. Foetal iodide results from maternal circulating iodide and from deiodination of iodothyronines within the placenta. The Na(+)/I(-) symporter (NIS) localized in placental cells appears to be involved in iodide exchange. Low NIS expression has been reported...

journal_title：Clinical endocrinology

authors： Di Cosmo C,Fanelli G,Tonacchera M,Ferrarini E,Dimida A,Agretti P,De Marco G,Vitti P,Pinchera A,Bevilacqua G,Naccarato AG,Viacava P

更新日期：2006-10-01 00:00:00

abstract：DESIGN:Prevalence of type 2 diabetes and glucose intolerance increase with age. It has been demonstrated that beta cell function declines at about 1% per year in glucose tolerant Caucasians. However, this relationship is not known to exist in other ethnic groups. SUBJECTS AND MEASUREMENTS:We investigated the relations...

journal_title：Clinical endocrinology

authors： Chiu KC,Martinez DS,Chu A

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVES:Papillary thyroid microcarcinoma (PTMC) has an excellent prognosis with an indolent disease course. However, some PTMCs have an aggressive course with lateral cervical lymph node (LCLN) metastasis or distant metastasis. This study aimed to evaluate the pre-operative features of PTMC associated with LCLN meta...

journal_title：Clinical endocrinology

authors： Jeon MJ,Chung MS,Kwon H,Kim M,Park S,Baek JH,Song DE,Sung TY,Hong SJ,Kim TY,Kim WB,Shong YK,Lee JH,Kim WG

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVES:Plasma C-reactive protein (CRP) is associated with cardiovascular disease (CVD), but effects may vary by gender and degree of CVD risk. Whether CRP has value as a CVD risk marker in type-2 diabetes (T2DM) is unclear. We examined whether CRP has gender differences in association with coronary artery calcium (...

journal_title：Clinical endocrinology

authors： Qasim AN,Budharaju V,Mehta NN,St Clair C,Farouk S,Braunstein S,Schutta M,Iqbal N,Rader DJ,Reilly MP

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To explore vitamin D status in relation to diabetes, based on data from a national health examination survey in Thailand. DESIGN AND METHODS:A total of 2641 adults, aged 15-98 years, were randomly selected according to geographical region from the Thai 4th National Health Examination Survey sample. Logistic ...

journal_title：Clinical endocrinology

authors： Chailurkit LO,Aekplakorn W,Ongphiphadhanakul B

更新日期：2012-11-01 00:00:00

abstract：:We describe a 40-year-old male with acromegaly, multiple and recurrent cutaneous myxomas, spotty cutaneous pigmentation, a mammary myxoma, a large-cell calcifying Sertoli cell tumour of the testis, and an unusual calcifying pigmented neuroectodermal tumour. He presented a combination of clinical and histological featu...

journal_title：Clinical endocrinology

authors： Leedman PJ,Cohen AK,Matz LR

更新日期：1986-11-01 00:00:00

abstract：OBJECTIVE:We wished to develop optimal criteria for interpreting the single-dose overnight metyrapone test and to compare the diagnostic efficiency of the overnight and the standard 6-dose metyrapone tests for the differential diagnosis of ACTH-dependent Cushing's syndrome. DESIGN:Retrospective pilot study based on al...

journal_title：Clinical endocrinology

authors： Avgerinos PC,Nieman LK,Oldfield EH,Cutler GB Jr

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:Little is known about the relationships of dietary factors, physical activity and sedentary behaviour to dehydroepiandrosterone sulphate (DHEAS) and insulin-like growth factor-1 (IGF-1) concentrations among prepubertal children. Therefore, we studied the associations of these lifestyle factors with serum DHEA...

journal_title：Clinical endocrinology

authors： Mäntyselkä A,Jääskeläinen J,Eloranta AM,Väistö J,Voutilainen R,Ong K,Brage S,Lakka TA,Lindi V

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:Human resistin gene (RETN) polymorphisms have been found to be associated with type 2 diabetes (T2DM), insulin resistance and/or obesity. We evaluated, in a 5-year prospective study, whether RETN polymorphisms could predict the progression of glycaemia in southern Chinese. DESIGN AND PATIENTS:We conducted a ...

journal_title：Clinical endocrinology

authors： Xu JY,Sham PC,Xu A,Tso AW,Wat NM,Cheng KY,Fong CH,Janus ED,Lam KS

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVE:The protein-tyrosine-phosphate nonreceptor 22 gene (PTPN22) has recently been identified as a susceptibility locus for a number of autoimmune diseases including Graves' disease (GD). PTPN21 is another member of the PTPN family and its gene PTPN21 maps to the first reported region of genetic linkage to GD, GD-...

journal_title：Clinical endocrinology

authors： Zeitlin AA,Heward JM,Brand OJ,Newby PR,Franklyn JA,Gough SC,Simmonds MJ

更新日期：2006-09-01 00:00:00

abstract：:In order to investigate the endocrine requirements for induction of follicle maturation, ovulation and luteal function we have measured plasma LH and FSH concentrations in 109 cycles induced by treatment with LHRH in 25 women with amenorrhoea of diverse aetiology. The major clinical and endocrine subgroupings were pol...

journal_title：Clinical endocrinology

authors： Abdulwahid NA,Adams J,van der Spuy ZM,Jacobs HS

更新日期：1985-12-01 00:00:00

abstract：:Alopecia is a frequent feature in hereditary resistance to (1,25(OH)2D). We sought insight into this feature by analysing data from affected members of 30 kindreds. We assessed indices of mineral metabolism in one group with normal hair compared with a group with alopecia. Hereditary resistance to 1,25(OH)2D was diagn...

journal_title：Clinical endocrinology

authors： Marx SJ,Bliziotes MM,Nanes M

更新日期：1986-10-01 00:00:00

abstract：:Bilateral, selective and simultaneous catheterization of the inferior petrosal sinus with measurements of ACTH after stimulation with ovine corticotrophin-releasing factor (CRF) is now frequently used to establish the differential diagnosis in patients with Cushing's disease and to determine the side of the microadeno...

journal_title：Clinical endocrinology

authors： Schulte HM,Allolio B,Günther RW,Benker G,Winkelmann W,Ohnhaus EE,Reinwein D

更新日期：1988-03-01 00:00:00

abstract：:In 63 consecutive patients with primary hyperparathyroidism (HPT) a prospective screening study was undertaken for coexistent multiple endocrine neoplasma-(MEN)-syndrome type 1. The screening consisted of a clinical examination, a radiological examination of the sella turcica with skeletal tomography (and in equivocal...

journal_title：Clinical endocrinology

authors： Muhr C,Ljunghall S,Akerstrom G,Palmér M,Bergström K,Enoksson P,Lundqvist G,Wide L

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:Mutations in PROP1, HESX1 and LHX3 are associated with combined pituitary hormone deficiency (CPHD) and orthotopic posterior pituitary lobe (OPP). OBJECTIVE:To identify mutations in PROP1, HESX1 and LHX3 in a large cohort of patients with CPHD and OPP (35 Brazilian, two Argentinian). DESIGN AND METHODS:We ...

journal_title：Clinical endocrinology

authors： Madeira JL,Nishi MY,Nakaguma M,Benedetti AF,Biscotto IP,Fernandes T,Pequeno T,Figueiredo T,Franca MM,Correa FA,Otto AP,Abrão M,Miras MB,Santos S,Jorge AA,Costalonga EF,Mendonca BB,Arnhold IJ,Carvalho LR

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:Women with Turner's syndrome (TS) have recently been shown to be at an increased risk of developing chronic liver disease. There has been some concern that oestrogen replacement therapy may exacerbate hepatic dysfunction. The aim of this study was to assess hepatic function in women with TS and to determine t...

journal_title：Clinical endocrinology

authors： Elsheikh M,Hodgson HJ,Wass JA,Conway GS

更新日期：2001-08-01 00:00:00

abstract：:Twenty women, who had been randomly selected from women with subclinical hypothyroidism identified in a population study were treated with L-thyroxine and placebo in a double-blind cross-over design during 2 x 6 months. Three women did not complete the study, one because she moved to another part of the country, and t...

journal_title：Clinical endocrinology

authors： Nyström E,Caidahl K,Fager G,Wikkelsö C,Lundberg PA,Lindstedt G

更新日期：1988-07-01 00:00:00

abstract：:Recombinant human TSH (rhTSH) has revolutionized the care of patients with differentiated thyroid cancer. Since its approval for clinical use in 2001 in Europe (1998 in the USA), rhTSH has greatly enhanced the surveillance of these patients by allowing the avoidance of hypothyroidism for TSH stimulation. Previously, a...

journal_title：Clinical endocrinology

authors： Woodmansee WW,Haugen BR

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:Whether nonalcoholic fatty liver disease (NAFLD) can predict atherosclerosis in obese patients remains unclear. The aim of our study was to investigate the usefulness of NAFLD and other cardiometabolic parameters in predicting subclinical atherosclerosis in obese patients. DESIGN, PATIENTS AND MEASUREMENTS:W...

journal_title：Clinical endocrinology

authors： Puig J,Blasco G,Daunis-I-Estadella J,Loshuertos E,Codina J,Cuba V,Ortiz R,Xifra G,Ricart W,Pedraza S,Federici M,Fernández-Real JM

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Iodide organification defects are frequently but not always associated with mutations in the thyroid peroxidase (TPO) gene and characterized by a positive perchlorate discharge test. These mutations phenotypically produce a congenital goitrous hypothyroidism, with an autosomal recessive mode of inheritance. ...

journal_title：Clinical endocrinology

authors： Rivolta CM,Louis-Tisserand M,Varela V,Gruñeiro-Papendieck L,Chiesa A,González-Sarmiento R,Targovnik HM

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:Appropriate replacement doses of glucocorticoid are important to determine in primary and secondary adrenal deficiency in children, both to avoid the risks of hypoglycaemia and adrenal crisis associated with undertreatment, and to avoid growth suppression and reduced final height potential associated with ste...

journal_title：Clinical endocrinology

authors： DeVile CJ,Stanhope R

更新日期：1997-07-01 00:00:00