Fused placentas: Till birth do us part.

abstract：INTRODUCTION/OBJECTIVES:Recent studies suggest redness (color) discordance of the placental basal plate may be a marker for twin anemia-polycythemia sequence (TAPS), a recently described complication of diamniotic-monochorionic twinning characterized by marked intertwin hemoglobin (Hb) discordance in the absence of oli...

journal_title：Placenta

authors： De Paepe ME,Gündoğan F,Mao Q,Chu S,Shapiro S

更新日期：2017-12-01 00:00:00

abstract：:Implantation in the dusky leaf monkey, Presbytis obscura, is superficial; the placenta is of the double discoid villous haemochorial type. Immediately prior to implantation the thick endometrium contains highly active uterine glands. There is an early uterine epithelial proliferation at the implantation site but no st...

journal_title：Placenta

authors： Burton GJ

更新日期：1980-07-01 00:00:00

abstract：INTRODUCTION:Non-invasive 3D imaging that enables clear visualization of placental margins is of interest in the accurate diagnosis of placental pathologies. This study investigated if contrast-enhanced MRI performed using a liposomal gadolinium blood-pool contrast agent (liposomal-Gd) enables clear visualization of th...

journal_title：Placenta

authors： Ghaghada KB,Starosolski ZA,Bhayana S,Stupin I,Patel CV,Bhavane RC,Gao H,Bednov A,Yallampalli C,Belfort M,George V,Annapragada AV

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:Histiotrophe is now recognized as being an important feature of early human pregnancy, providing nutrients and growth factors to the developing embryo. Our aim was to examine the glycan composition of histiotrophe from first trimester decidua and to compare it with secretions present in endometrial glands fr...

journal_title：Placenta

authors： Jones CJ,Aplin JD,Burton GJ

更新日期：2010-07-01 00:00:00

abstract：:There is accumulating evidence that deficient trophoblast invasion of the placental bed spiral arteries is crucial to the pathogenesis of pre-eclampsia and intrauterine growth restriction. However, the factors which regulate the process of trophoblast invasion remain unclear. We have investigated whether extravillous ...

journal_title：Placenta

authors： Lash GE,Cartwright JE,Whitley GS,Trew AJ,Baker PN

更新日期：1999-11-01 00:00:00

abstract：INTRODUCTION:Little is known about the interaction between human placental multipotent mesenchymal stromal cell (hPMSC) and trophoblast. We hypothesize that hPMSCs produce hepatocyte growth factor (HGF) which may interact with trophoblasts and regulate their migration during placentation. METHODS:hPMSCs were isolated ...

journal_title：Placenta

authors： Chen CP,Huang JP,Chu TY,Aplin JD,Chen CY,Wu YH

更新日期：2013-10-01 00:00:00

abstract：:Human papillomavirus (HPV) are more prevalent in spontaneous abortions than elect abortions and preferentially infect the trophoblasts. Related to this, HPV type 16 has been shown to productively replicate in 3A trophoblasts in tissue culture. Extending these earlier studies, the described study addresses the issue wh...

journal_title：Placenta

authors： You H,Liu Y,Agrawal N,Prasad CK,Edwards JL,Osborne AF,Korourian S,Lowery CL,Hermonat PL

更新日期：2008-01-01 00:00:00

abstract：:Phorbol myristate acetate (PMA) and all-trans-retinal (retinal) were evaluated as possible phagocytic stimulators of cultured, post implantation, trophoblast cells. Ectoplacental cones dissected from 7.5 day-old mouse embryos provided the source of trophoblastic cells. Co-cultures were performed using stimulated and n...

journal_title：Placenta

authors： Albieri A,Bevilacqua E

更新日期：1996-09-01 00:00:00

abstract：:The proliferation and differentiation of trophoblast cells is under the control of a variety of hormones and growth factors and is influenced by nutrient availability. The intracellular signaling pathways acting downstream of these mitogenic factors and nutrients to regulate trophoblast proliferation and placental dev...

journal_title：Placenta

authors： Wen HY,Abbasi S,Kellems RE,Xia Y

更新日期：2005-04-01 00:00:00

abstract：:The placenta provides all energy and nutrient requirements for healthy fetal development. The placenta in rats is capable of storing glycogen, although the placenta cells must therefore mobilize stored glycogen to its own glucose supply. Moreover, maternal glucose and/or placental lactate furnished the fetal growth. A...

journal_title：Placenta

authors： Toledo MT,Gomes Marcondes MC

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:Maternal magnesium (Mg) deficiency has been associated with fetal growth restriction. Using a mouse model of maternal Mg deficiency-induced fetal growth restriction, we sought to investigate the effect of Mg deficiency on placental physiology and function. METHODS:In vivo: Pregnant Swiss Webster mice were fe...

journal_title：Placenta

authors： Rosner JY,Gupta M,McGill M,Xue X,Chatterjee PK,Yoshida-Hay M,Robeson W,Metz CN

更新日期：2016-03-01 00:00:00

abstract：:The visceral yolk sac (VYS) is responsible for a major part of the amino acid nutrition of the early post-implantation rat embryo and possibly also at the fetal stage of gestation. The mechanism involves endocytic uptake of proteins by the tissue's epithelial cells followed by intralysosomal digestion to amino acids. ...

journal_title：Placenta

authors： Pratten MK,Lloyd JB

更新日期：1997-09-01 00:00:00

abstract：OBJECTIVE:Pregestational maternal obesity (PGMO) associates with foetoplacental vascular endothelial dysfunction and higher risk for insulin resistance in the neonate. We characterised the PGMO consequences on the insulin response of the human foetoplacental vasculature. METHODS:Umbilical veins were from pregnancies w...

journal_title：Placenta

authors： Villalobos-Labra R,Westermeier F,Pizarro C,Sáez PJ,Toledo F,Pardo F,Kusanovic JP,Mardones F,Poblete JA,Sobrevia L,Farías M

更新日期：2019-10-01 00:00:00

abstract：:The sites of localization of luteinizing hormone (LH), follicle-stimulating hormone (FSH), growth hormone (GH), adrenocorticotrophic hormone (ACTH) and prolactin (PRL) within placental tissues have been studied by an immunoperoxidase technique. The syncytiotrophoblast is the sole significant site of localization of LH...

journal_title：Placenta

authors： Al-Timimi A,Fox H

更新日期：1986-03-01 00:00:00

abstract：:Human trophoblast research relies on a combination of in vitro models, including isolated primary cultures, explant cultures, and trophoblast cell lines. In the present study, we have utilized the rotating wall vessel (RWV) bioreactor to generate a three-dimensional (3-D) model of human placentation for the study of c...

journal_title：Placenta

authors： LaMarca HL,Ott CM,Höner Zu Bentrup K,Leblanc CL,Pierson DL,Nelson AB,Scandurro AB,Whitley GS,Nickerson CA,Morris CA

更新日期：2005-11-01 00:00:00

abstract：:The uterine endometrium responds to blastocyst implantation with extensive proliferation and differentiation of stromal cells into decidual cells, forming the antimesometrial and mesometrial decidua. These undergo regression by apoptosis but as this process occurs at different time periods suggest that there is spatia...

journal_title：Placenta

authors： Correia-da-Silva G,Bell SC,Pringle JH,Teixeira NA

更新日期：2005-11-01 00:00:00

abstract：:The binding of oestradiol in human placental tissue obtained from spontaneous and caesarean deliveries was investigated. Villous tissue was homogenized and the 800 g 'cytosol' supernatant treated with ammonium sulphate. The precipitate was redissolved and the preparation then equilibrated with [3H]oestradiol. After se...

journal_title：Placenta

authors： Laminski NA,Hammond KD

更新日期：1985-09-01 00:00:00

abstract：INTRODUCTION:The decidual reaction and the formation of new vessels in the uterus are two crucial processes during embryo implantation. Previously, we observed that lysophosphatidic acid (LPA) increases cyclooxygenase-2 derived - prostaglandin E2 production during implantation in the rat uterus and that it augments the...

journal_title：Placenta

authors： Beltrame JS,Sordelli MS,Cella M,Perez Martinez S,Franchi AM,Ribeiro ML

更新日期：2013-09-01 00:00:00

abstract：:Maternal and fetal cellular relationships in the normal human term placental basal plate were investigated by single and double immunohistochemical labelling techniques. Extravillous fetal trophoblast in the basal plate was uniformly reactive with markers of low-molecular-weight cytokeratins. The predominant maternal ...

journal_title：Placenta

authors： Bulmer JN,Smith J,Morrison L,Wells M

更新日期：1988-05-01 00:00:00

abstract：:We present a mathematical model for maternal blood flow in a placental circulatory unit (a placentone), describing flow of maternal blood via Darcy's law and steady advective transport of a dissolved nutrient. The method of images and computational integration along streamlines are employed to find flow and solute con...

journal_title：Placenta

authors： Chernyavsky IL,Jensen OE,Leach L

更新日期：2010-01-01 00:00:00

abstract：:We investigated the localization of the three subtypes of (Fc gamma R) in the normal human placenta using immunohistochemical and immunocytochemical techniques with specific monoclonal antibodies. The analysis revealed that Fc gamma RI was expressed on Hofbauer cells, that Fc gamma RII was expressed on Hofbauer cells ...

journal_title：Placenta

authors： Kameda T,Koyama M,Matsuzaki N,Taniguchi T,Saji F,Tanizawa O

更新日期：1991-01-01 00:00:00

abstract：INTRODUCTION:Infection accounts for over 40% of preterm premature rupture of the fetal membranes (PPROM), a major cause of preterm birth. Toll-like receptors (TLR) play key roles in pathogen surveillance but their expression and function in amnion mesenchymal cells (AMC) is unclear. The aims of this study were to deter...

journal_title：Placenta

authors： Sato BL,Collier ES,Vermudez SA,Junker AD,Kendal-Wright CE

更新日期：2016-08-01 00:00:00

abstract：:ED(27) trophoblast-like cells were prepared from human chorionic villus samples obtained at 9 weeks gestation and have been grown continuously in vitro without phenotypic drift for nearly a decade. These cells express many trophoblast markers, including cytokeratin, placental alkaline phosphatase (PLAP), secretion of ...

journal_title：Placenta

authors： Kniss DA,Xie Y,Li Y,Kumar S,Linton EA,Cohen P,Fan-Havard P,Redman CW,Sargent IL

更新日期：2002-01-01 00:00:00

abstract：:Accumulation of advanced oxidation protein products (AOPPs) is prevalent in obesity, advanced maternal age, diabetes mellitus, and polycystic ovary syndrome. Alterations in the regulation and signaling of angiogenic pathways have been recognized as a link between these conditions and pre-eclampsia. To investigate the ...

journal_title：Placenta

authors： Huang QT,Wang SS,Zhang M,Huang LP,Tian JW,Yu YH,Wang ZJ,Zhong M

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are small single-stranded RNA molecules working as post-transcriptional modulators of gene expression. Trophoblast cells are a heterogenous group of fetal cells forming the feto-maternal interface and displaying a wide spectrum of functions. The regulation of their behavior may partly unde...

journal_title：Placenta

authors： Morales-Prieto DM,Chaiwangyen W,Ospina-Prieto S,Schneider U,Herrmann J,Gruhn B,Markert UR

更新日期：2012-09-01 00:00:00

abstract：:Marijuana is one of the most abused drugs among pregnant women leading to maternal and fetal abnormalities. Cannabinoids are the active ingredients of marijuana, which interact with cannabinoid receptors such as CNR1 and CNR2 to activate cellular signaling pathways. Human endometrium and placenta are known to express ...

journal_title：Placenta

authors： Neradugomma NK,Drafton K,O'Day DR,Liao MZ,Han LW,Glass IA,Mao Q

更新日期：2018-06-01 00:00:00

abstract：INTRODUCTION:Air pollution has significant negative health impacts, particularly on the cardiovascular system. The aims of this narrative review were to identify whether there is an association between air pollution and the incidence of pre-eclampsia, and the potential mechanisms by which any effects may be mediated. ...

journal_title：Placenta

authors： Bearblock E,Aiken CE,Burton GJ

更新日期：2020-12-18 00:00:00

abstract：:The ANP knockout mouse is reported to exhibit pregnancy-associated hypertension, proteinuria and impaired placental trophoblast invasion and spiral artery remodeling, key features of pre-eclampsia (PE). We hypothesized that these mice may provide a relevant model of human PE with associated fetal growth restriction (F...

journal_title：Placenta

authors： Finn-Sell SL,Renshall LJ,Cowley EJ,Dilworth MR,Wareing M,Greenwood SL,Sibley CP,Cottrell EC

更新日期：2016-06-01 00:00:00

abstract：:Dynamics of genome multiplication during establishment of interrelations between trophoblast and glandular epithelium of the endometrium has been studied in the course of formation of placenta in the silver fox. During formation of the placenta, penetration of the trophoblast into the zone of the endometrial glandular...

journal_title：Placenta

authors： Zybina TG,Zybina EV,Kiknadze II,Zhelezova AI

更新日期：2001-05-01 00:00:00

abstract：:Eighty-one placentae from women with leprosy and 17 placentae from healthy controls were subjected to a detailed macroscopic, light microscopic, ultrastructural, immunopathological, microbiological and biochemical study. The placental morphology and immunohistology were normal, and there was no morphological evidence ...

journal_title：Placenta

authors： Duncan ME,Fox H,Harkness RA,Rees RJ

更新日期：1984-05-01 00:00:00