Efficacy of DA-5204 (Stillen 2X) for patients with gastroesophageal reflux disease: A randomized, double-blind, placebo-controlled pilot study.

abstract：BACKGROUND:Knee osteoarthritis (KOA) is a common degenerative joint disorder that affects 250 million people globally. KOA can lead to disability and is often associated with cardiovascular disease, poor quality of life, and mortality. The most common treatment for KOA is non-steroidal anti-inflammatory drug administra...

journal_title：Medicine

authors： Wu SY,Lin CH,Chang NJ,Hu WL,Hung YC,Tsao Y,Kuo CA

更新日期：2020-03-01 00:00:00

abstract：:The goal of this study was to evaluate the potential relationship among polymorphisms of aromatic hydrocarbon receptor, aromatic hydrocarbon receptor repressor, and rheumatoid arthritis (RA) susceptibility as well as the association among the polymorphisms of aromatic hydrocarbon receptor, aromatic hydrocarbon recepto...

journal_title：Medicine

authors： Cheng L,Qian L,Wang GS,Li XM,Li XP

更新日期：2017-04-01 00:00:00

abstract：:Atrial remodeling plays a significant role during the progression of atrial fibrillation (AF). Left atrial wall thickness (LAT) is a subjective and easily acquirable indicator referring to structural remodeling. Therefore, we aimed to investigate the association between LAT and atrial remodeling substrate, and to expl...

journal_title：Medicine

authors： Zuo K,Li K,Liu M,Li J,Liu X,Liu X,Zhong J,Yang X

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:Chronic active Epstein-Barr virus (EBV) infection (CAEBV) is characterized as chronic or recurrent mononucleosis-like symptoms and elevated EBV deoxyribonucleic acid (EBV-DNA) copies. Cardiovascular complications have high morbidity and mortality. The treatment regimen for CAEBV has not been established ye...

journal_title：Medicine

authors： Jiang S,Li X,Cao J,Wu D,Kong L,Lin L,Jin Z,An J,Wang Y

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:The surgical pleth index (SPI) is proposed for titration of analgesic drugs during general anesthesia. Several reports have investigated the effect of SPI on the consumption of opioids including remifentanil, fentanyl, and sufentanil during anesthesia, but there are no reports about oxycodone. We aimed to in...

journal_title：Medicine

authors： Won YJ,Lim BG,Lee SH,Park S,Kim H,Lee IO,Kong MH

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:A possible association between metformin use and the development of prostate cancer (PCa) has been reported. However, there is limited information on the impact of long-term metformin use on serum prostate-specific antigen (PSA) levels. We investigated the association between exposure to metformin and PSA level...

journal_title：Medicine

authors： Park JS,Lee KS,Ham WS,Chung BH,Koo KC

更新日期：2017-12-01 00:00:00

abstract：INTRODUCTION:Lymphoma is the third most common cancer among children in the United States and Europe. Hemophilia is a congenital bleeding disorder characterized by deficiency of coagulation factor VIII or IX. Hemophilia B is a consequence of factor IX deficiency and has an incidence of 1 in 20,000 male births. A concur...

journal_title：Medicine

authors： Lu G,Qiao L,Li D,Liu Z,Zhao F,Yu D

更新日期：2019-05-01 00:00:00

abstract：INTRODUCTION:Acute hydrocephalus is a common complication of spontaneous or traumatic intracranial bleeding with extensive subarachnoid hemorrhage (SAH) or ventricular extension. However, it has never been reported to be secondary to pneumocephalus. PATIENT CONCERNS:A 32-year-old man was admitted following a motorcycl...

journal_title：Medicine

authors： Li G,Wang G,Luan T,Hou K,Yu J

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Early diagnosis and treatment of the osteonecrosis of the femoral head (ONFH), a refractory disease, is imperative to prevent femoral head collapse; however, the existing solutions remain controversial. This study assessed the safety and efficacy of extracorporeal shock wave therapy (ESWT) combined with mult...

journal_title：Medicine

authors： Li Q,Chen R,Yu Y,Wang X,Feng X,Jiang L,Chen B,Xin P,Li T,Shi Y,Jian Q,Jiang Z,Fan X

更新日期：2020-10-02 00:00:00

abstract：:Familial amyloid polyneuropathy (FAP) is an autosomal dominant disease associated with the mutations in the transthyretin gene. To date, the endoscopic findings of the small-bowel lesions of FAP have never been described. We report a rare case of FAP with gastrointestinal involvement. A 71-year-old woman complaining o...

journal_title：Medicine

authors： Asakura K,Yanai S,Nakamura S,Kawaski K,Eizuka M,Ishida K,Sugai T,Ueda M,Yamashita T,Ando Y,Matsumoto T

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:To explore that if mid-regional sequence of pro-A-type natriuretic peptide (MR-proANP) may have a good value of diagnosis in heart failure with preserved ejection fraction (HFpEF) compared with N-terminal pro-B-type natriuretic peptide (NT-proBNP). METHODS:Participants with cardiovascular disease who were e...

journal_title：Medicine

authors： Cui K,Huang W,Fan J,Lei H

更新日期：2018-09-01 00:00:00

abstract：:Mastocytosis is a rare disease characterized by clonal neoplastic proliferation of mast cells (MCs). It ranges from skin lesions as cutaneous mastocytosis (CM) which may spontaneously regress to highly aggressive neoplasms with multiorgan involvement corresponding to some aggressive systemic mastocytosis (ASM), mast c...

journal_title：Medicine

authors： Russano de Paiva Silva G,Tournier E,Sarian LO,Bulai-Livideanu C,Delsol G,Lamant L,Vassallo J,Brousset P,Laurent C

更新日期：2018-05-01 00:00:00

abstract：:Autoimmune myelofibrosis is a distinct clinicopathologic entity that occasionally occurs with autoimmune disorders such as systemic lupus erythematosus (SLE) and rheumatoid arthritis. Most cases of autoimmune myelofibrosis have been reported in female patients with a known history of SLE. We report a case of a middle-...

journal_title：Medicine

authors： Pundole X,Konoplev S,Oo TH,Lu H

更新日期：2015-05-01 00:00:00

abstract：RATIONALE:Intraductal papillary and mucinous neoplasms of the pancreas (IPMN) are preneoplastic lesions diagnosed with an increasing incidence. Recently, several groups have described, in up to 70% of IPMN, activating mutations of the G-protein alpha stimulatory sub-unit (Gsα subunit) gene (GNAS). GNAS-activating somat...

journal_title：Medicine

authors： Gaujoux S,Pasmant E,Silve C,Mehsen-Cetre N,Coriat R,Rouquette A,Douset B,Prat F,Leroy K

更新日期：2019-12-01 00:00:00

abstract：RATIONALE:Henoch-Schönlein purpura (HSP) is a small-vessel vasculitis that has been extensively studied in children, but little is known about its natural history in adults. There is no consensus regarding the treatment of glucocorticosteroids use for HSP. The efficacy of glucocorticoid for preventing from severe compl...

journal_title：Medicine

authors： Yi F,Bai Z,Li Y,Xu X,Guo X,Qi X

更新日期：2020-01-01 00:00:00

abstract：RATIONALE:Frontometaphyseal dysplasia (FMD) is a dominant X-linked rare disease caused by mutations of FLNA. The distinctive features of FMD include skeletal dysplasia, facial dysmorphism, extremities anomalies, deafness, cleft palate and eye anterior segment anomalies, yet none of the complications, such as acro-osteo...

journal_title：Medicine

authors： Xie H,Xue L,Hua W,Jia B,Zhang L,Li L

更新日期：2018-07-01 00:00:00

abstract：:Early life family relationships affect the sexuality in adulthood, and these influences might be reflected in sexual dreams. The present study was designed to investigate the exact associations between family relationships and sexual dream experience. We therefore invited 62 frequent sexual dreamers (dreamers) and 104...

journal_title：Medicine

authors： Shao X,Wang C,Jia Y,Wang W

更新日期：2020-09-04 00:00:00

abstract：:The public sector scale-up of antiretroviral therapy (ART) in South Africa commenced in 2004. We aimed to describe the hospital-level disease burden and factors contributing to morbidity and mortality among hospitalized HIV-positive patients in the era of widespread ART availability. Between June 2012 and October 2013...

journal_title：Medicine

authors： Meintjes G,Kerkhoff AD,Burton R,Schutz C,Boulle A,Van Wyk G,Blumenthal L,Nicol MP,Lawn SD

更新日期：2015-12-01 00:00:00

abstract：INTRODUCTION:Amyotrophic lateral sclerosis (ALS) is the most common cause of motor neuron disease, and effective treatment for ALS is still lacking. Transactive response (TAR) -DNA-binding protein-43 (TDP-43) is aggregated in the neurons of ALS patients. Animal studies shown TDP-43 aggregation can be attenuated by enha...

journal_title：Medicine

authors： Chen PC,Hsieh YC,Huang CC,Hu CJ

更新日期：2020-05-29 00:00:00

abstract：INTRODUCTION:Arginine is an essential amino acid that plays an important role in various body functions including cell division, wound healing, removal of ammonia, immune function, and release of hormones. Hyperargininemia, an autosomal recessive genetic disorder, is considered one of the least common urea cycle disord...

journal_title：Medicine

authors： Bakhiet M,AlAwadi AMI,AlHammadi MM,Ali MF,Butti N

更新日期：2018-05-01 00:00:00

abstract：RATIONALE:Immunosuppressive agents such as tacrolimus (TAC) and cyclosporin might cause glycemic disorders by suppressing insulin production. However, only a few cases of diabetic ketoacidosis (DKA) with longitudinal evaluation of endogenous insulin secretion related to TAC administration have been reported. PATIENT C...

journal_title：Medicine

authors： Maruyama K,Chujo D

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:To determine the efficacy of magnetic stimulation (MS) in female patients with stress urinary incontinence (SUI) by performing a meta-analysis on peer-reviewed randomized controlled trails (RCTs). METHODS:PubMed, Embase, and Cochrane library were retrieved for any peer-reviewed original articles in English....

journal_title：Medicine

authors： Peng L,Zeng X,Shen H,Luo DY

更新日期：2019-05-01 00:00:00

abstract：:Maternal bacterial sepsis during pregnancy and the postpartum period is a common cause of maternal mortality and fetal morbidity and mortality. This study was performed to analyze perinatal prognosis and related factors of maternal bacterial sepsis in west China.We conducted a cross-sectional study of pregnant women w...

journal_title：Medicine

authors： Duan R,Xu X,Wang X,Yu H

更新日期：2019-11-01 00:00:00

abstract：:Tuberculosis (TB) disease may be transmitted to close contacts of index cases, causing physical illness. No studies have investigated the risk of developing depressive disorder among TB contacts in a TB-endemic area.Adult participants with a new diagnosis of TB contact (ICD-9-CM codes V01.1 plus chest radiographic ord...

journal_title：Medicine

authors： Pan SW,Yen YF,Feng JY,Su VY,Kou YR,Su WJ

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Breast cancer survivors experience various symptoms associated with their cancer interventions, and the benefits of acupuncture for these symptoms have been evaluated in clinical trials worldwide. The purpose of this review was to discuss the current status of clinical research regarding the use of acupunctu...

journal_title：Medicine

authors： Kim TH,Kang JW,Lee MS

更新日期：2018-08-01 00:00:00

abstract：:To evaluate the utility of blood pressure variability (BPV) calculated using previously published and newly introduced indices using the variables falls and age as comparators.While postural hypotension has long been considered a risk factor for falls, there is currently no documented evidence on the relationship betw...

journal_title：Medicine

authors： Goh CH,Ng SC,Kamaruzzaman SB,Chin AV,Poi PJH,Chee KH,Imran ZA,Tan MP

更新日期：2016-05-01 00:00:00

abstract：:Although published studies have reported the association between MTHFR C677T (rs 1801133), A1298C (rs 1801131), and MTRR A66G (rs1801394) polymorphisms and male infertility in Asian populations, the results are conflicting. In order to accurately evaluate the relevance, a meta-analysis was performed.We searched for po...

journal_title：Medicine

authors： Shi TL,Wu Y,Li Y,Chen ZF,Ma YN,Zhang ZT,Zhang YH,Zhang L

更新日期：2019-02-01 00:00:00

abstract：RATIONALE:Traumatic bilateral facet dislocation in the lumbar (L) spine has rarely been reported. All reported cases were presented with acute facet dislocation. However, we present the first case of delayed bilateral facet dislocation at L4-5. PATIENT CONCERNS:A 34-year-old woman presented with back pain after a head...

journal_title：Medicine

authors： Park HY,Ha KY,Kim YH,Kim SI,Min HK,Oh IS,Seo JY,Chang DG,Alhazmi MA,Cho JH

更新日期：2018-09-01 00:00:00

abstract：:This study aims to explore the effect of oxycodone hydrochloride injection on the immune function of patients who underwent radical resection of rectal cancer under general anesthesia.Eighty patients were enrolled and randomly divided into group A and B (n = 40, each). All patients underwent general intravenous anesth...

journal_title：Medicine

authors： Cui JH,Jiang WW,Liao YJ,Wang QH,Xu M,Li Y

更新日期：2017-08-01 00:00:00

abstract：:In a retrospective analysis of 40 hospitalized patients with the Guillain-Barré syndrome (GBS), we related the use and outcome of assisted ventilation to specific quantitative details of the neurologic illness. Two patients had an unusually prolonged course: they were ventilated for 374 and 396 days before successful ...

journal_title：Medicine

authors： Sunderrajan EV,Davenport J

更新日期：1985-09-01 00:00:00