Abstract:
:Cyanobacteria are Gram-negative photoautotrophic prokaryotes and have shown great importance to the Earth's ecology. Based on their capability in oxygenic photosynthesis and genetic merits, they can be engineered as microbial chassis for direct conversion of carbon dioxide to value-added biofuels and chemicals. In the last decades, attempts have given to the application of synthetic biology tools and approaches in the development of cyanobacterial cell factories. Despite the successful proof-of-principle studies, large-scale application is still a technical challenge due to low yields of bioproducts. Therefore, recent efforts are underway to characterize and develop genetic regulatory parts and strategies for the synthetic biology applications in cyanobacteria. In this review, we present the recent advancements and application in cyanobacterial synthetic biology toolboxes. We also discuss the limitations and future perspectives for using such novel tools in cyanobacterial biotechnology.
journal_name
Bioengineeredjournal_title
Bioengineeredauthors
Wang F,Gao Y,Yang Gdoi
10.1080/21655979.2020.1837458subject
Has Abstractpub_date
2020-12-01 00:00:00pages
1208-1220issue
1eissn
2165-5979issn
2165-5987journal_volume
11pub_type
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