Abstract:
BACKGROUND:The scale of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among health care workers (HCWs), particularly in resource-limited settings, remains unclear. To address this concern, universal (non-symptom-based) screening of HCWs was piloted to determine the proportion of SARS-CoV-2 infection and the associated epidemiological and clinical risk factors at a large public health care facility in Egypt. METHODS:Baseline voluntary screening of 4040 HCWs took place between 22 April and 14 May 2020 at 12 hospitals and medical centres in Cairo. Epidemiological and clinical data were collected using an online survey. All participants were tested for SARS-CoV-2 using reverse transcription polymerase chain reaction (RT-PCR) and rapid IgM and IgG serological tests. RESULTS:Of the 4040 HCWs screened, 170 [4.2%; 95% confidence interval (CI): 3.6-4.9] tested positive for SARS-CoV-2 by either of the three tests (i.e. infected); 125/170 (73.5%) tested PCR-positive. Most infected HCWs were nurses (97/170, 57.5%). Median age of infected HCWs was 31.5 [interquartile range (IQR): 27.0-41.3] years. Of infected HCWs, 78 (45.9%) reported contact with a suspected case and 47 (27.6%) reported face-to-face contact within 2 m with a confirmed case. The proportion of infection among symptomatic HCWs (n = 54/616) was 8.8% (95% CI: 6.7-11.3); 6/54 (11.1%) had fever ≥38°C and 7/54 (13.0%) reported severe symptoms. Most infected HCWs were asymptomatic (116/170, 68.2%). The proportion of infection among asymptomatic HCWs (n = 116/3424) was 3.4% (95% CI: 2.8-4.0). CONCLUSIONS:The high rate of asymptomatic infections among HCWs reinforces the need for expanding universal regular testing. The infection rate among symptomatic HCWs in this study is comparable with the national rate detected through symptom-based testing. This suggests that infections among HCWs may reflect community rather than nosocomial transmission during the early phase of the COVID-19 epidemic in Egypt.
journal_name
Int J Epidemioljournal_title
International journal of epidemiologyauthors
Mostafa A,Kandil S,El-Sayed MH,Girgis S,Hafez H,Yosef M,Saber S,Ezzelarab H,Ramadan M,Afifi I,Hassan F,Elsayed S,Reda A,Fattuh D,Mahmoud A,Mansour A,Sabry M,Habeb P,Ebeid FS,Saleh A,Mansour O,Omar A,El-Meteinidoi
10.1093/ije/dyaa173subject
Has Abstractpub_date
2020-10-23 00:00:00eissn
0300-5771issn
1464-3685pii
5936053pub_type
杂志文章abstract::The familial aggregation of chronic bronchitis and obstructive airways disease was investigated in a propositus population of 430 persons aged 45-54 years and 1340 of their first (1 degree), second (2degrees) and third (3 degrees ) order relatives. All subjects were screened in their homes using a modified British MRC...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/7.1.55
更新日期:1978-03-01 00:00:00
abstract:BACKGROUND:In Switzerland, assisted suicide is legal but there is concern that vulnerable or disadvantaged groups are more likely to die in this way than other people. We examined socio-economic factors associated with assisted suicide. METHODS:We linked the suicides assisted by right-to-die associations during 2003-0...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyu010
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:A number of studies have reported that increased consumption of natural products reduced the risk of cancer. Our previous case-control studies have shown a significant reduction in the risk of cancer development among those who regularly consumed ginseng. We conducted a prospective cohort study to evaluate t...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/27.3.359
更新日期:1998-06-01 00:00:00
abstract::The area under the receiver operating characteristic (ROC) curve (AUC) is commonly used for assessing the discriminative ability of prediction models even though the measure is criticized for being clinically irrelevant and lacking an intuitive interpretation. Every tutorial explains how the coordinates of the ROC cur...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyz274
更新日期:2020-08-01 00:00:00
abstract::This paper provides a brief overview to four major types of causal models for health-sciences research: Graphical models (causal diagrams), potential-outcome (counterfactual) models, sufficient-component cause models, and structural-equations models. The paper focuses on the logical connections among the different typ...
journal_title:International journal of epidemiology
pub_type: 杂志文章,评审
doi:10.1093/ije/31.5.1030
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:Maternal mortality from complications of unsafe abortion constitutes a serious problem in several developing countries. There is, however, a paucity of well-designed and implemented studies in this area, especially in Latin America. The aim of this paper is to present the findings on the determinants and med...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/27.5.833
更新日期:1998-10-01 00:00:00
abstract:BACKGROUND:The objective of the study was to estimate the prevalence of gonorrhoea and chlamydial infections and to determine sexual and demographic correlates for these sexually transmitted diseases (STD) among visitors of an STD clinic. METHODS:In 1994, a cross-sectional study was carried out among 2984 consecutive ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/26.6.1373
更新日期:1997-12-01 00:00:00
abstract:BACKGROUND:There is considerable interest in the possible role of nitrate in gastric carcinogenesis, but little information on nitrate intake around the world. This is the first study to give comprehensive standardised data on nitrate excretion as a marker of intake, using 48 worldwide population samples. METHODS:Urin...
journal_title:International journal of epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1093/ije/25.3.505
更新日期:1996-06-01 00:00:00
abstract::Aboriginal communities have a high prevalence of upper and lower respiratory tract disease. One thousand two hundred and eighty seven West Australian Aborigines and 265 non-Aborigines were examined. Twenty nine per cent of Aborigines had lower respiratory tract abnormalities. Amongst 635 Aboriginal children less than ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/12.1.105
更新日期:1983-03-01 00:00:00
abstract:Background:Acute rheumatic fever (ARF) has largely disappeared from high-income countries. However, in New Zealand (NZ) rates remain high in indigenous (Māori) and Pacific populations. In 2011, NZ launched an intensive and unparalleled primary Rheumatic Fever Prevention Programme (RFPP). We evaluated the impact of the ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyy150
更新日期:2018-10-01 00:00:00
abstract::Mortality rates from ischaemic heart disease (IHD) in Australia for the period 1969-78 have been analysed by place of residence, occupation and country of birth. Large variations were found among subpopulations. Throughout the period IHD mortality was lowest among professional and farming occupations and highest among...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/13.1.25
更新日期:1984-03-01 00:00:00
abstract::The relationship of parents' cigarette smoking to outcome of pregnancy-implications as to the problem of inferring causation from observed associations. Amer J Epidem 1971;93:443-456. Nearly 10,000 white and more than 3000 black women were interviewed early in pregnancy on a variety of medical, genetic, environmental,...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyu160
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Although the Expanded Programme on Immunization (EPI) cluster survey methodology has been successfully used for assessing levels of immunization programme coverage in developing country settings, certain features of the methodology, as it is usually carried out, make it less-than-optimal choice for large, na...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/25.1.198
更新日期:1996-02-01 00:00:00
abstract:BACKGROUND:A recent monograph by the International Agency for Research on Cancer (IARC) has identified indoor air pollution from coal usage as a known human carcinogen, while that from biomass as a probable human carcinogen. Although as much as 74% of the Indian population relies on solid fuels for cooking, very little...
journal_title:International journal of epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1093/ije/dym261
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Second-hand smoke is associated with adverse health effects. Many countries have extended smoke-free policies to public buildings and workplaces such as hospitals, but mental health units have usually been exempted from complete smoke-free bans. The objective of this study was to evaluate second-hand smoke l...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyt014
更新日期:2013-06-01 00:00:00
abstract::This study gives results for comparisons between dietary history interviews repeated at short-term (4-8 months) and long-term (4-7 years) intervals in conjunction with the Finnish Mobile Clinic Health Examination Survey. Interviews surveying the whole range of consumable foods over the preceding year were completed in...
journal_title:International journal of epidemiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/ije/22.3.520
更新日期:1993-06-01 00:00:00
abstract::The STEPS Study aims to search for the precursors and causes of problems in child health and well-being by using a multidisciplinary approach. The cohort consists of all mothers (Finnish or Swedish speaking) who had live deliveries in the Hospital District of Southwest Finland from January 2008 to April 2010 and their...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dys150
更新日期:2013-10-01 00:00:00
abstract::Few data on birthweight distributions are available for Zimbabwe. This paper reports a study of 2140 births in Harare, Zimbabwe, occurring in April 1986. Births took place in public facilities, which are estimated to serve 85% of the urban population. Mean birthweight for the entire sample is 2970 g, and for singleton...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/19.1.98
更新日期:1990-03-01 00:00:00
abstract::The Ballabgarh Health and Demographic Surveillance System (HDSS), also known as the Comprehensive Rural Health Services Project (CRHSP) Ballabgarh, is located in north India and was established in 1961 to develop a model for rural health-care practice in India. In addition to demographic surveillance and community-bas...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyt055
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:The incidence rates of childhood onset type 1 diabetes are almost universally increasing across the globe but the aetiology of the disease remains largely unknown. We investigated whether birth order is associated with the risk of childhood diabetes by performing a pooled analysis of previous studies. METHO...
journal_title:International journal of epidemiology
pub_type: 杂志文章,meta分析,评审
doi:10.1093/ije/dyq207
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:While dietary patterns that are both predictive of chronic disease and mortality have been identified, the confounding effects of cardiorespiratory fitness have not been properly addressed. The primary objective was to assess the relation between dietary patterns with all-cause mortality, while controlling f...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyp191
更新日期:2010-02-01 00:00:00
abstract::Geographical variations in the declining rates of ischaemic heart disease (IHD) mortality may provide clues about various environmental risk factors responsible as a mass influence on the population IHD rate. The rate of IHD decline in 18 of 21 NJ counties was 2 to 45% less than the USA national rate of decline. The o...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/19.1.26
更新日期:1990-03-01 00:00:00
abstract::Socioeconomic conditions are important in explaining variation in cardiovascular morbidity in advanced societies. To analyse whether cardiovascular risk factors vary according to socioeconomic status in a developing country, and more specifically, in an urban area of China, we compared data from structured interviews ...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/19.4.905
更新日期:1990-12-01 00:00:00
abstract::Seemingly contradictory data support controversies concerning the relationships between food intake and illnesses. The present study of 1035 adults, aged 30-39 years, shows that (1) daily energy intake is not higher in obese than in non-obese people, (2) obesity is more prevalent in social groups where energy intake i...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/19.3.571
更新日期:1990-09-01 00:00:00
abstract:BACKGROUND:The significance of persistent or recurrent respiratory infections in adult life for the development of chronic obstructive pulmonary disease (COPD) is still to a large extent unknown. A few clinical and experimental animal studies suggest that peripheral airways diseases may be due to the cumulative effects...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/25.3.658
更新日期:1996-06-01 00:00:00
abstract::The Shahroud Eye Cohort Study was set up to determine the prevalence and incidence of visual impairment and major eye conditions in the 40-64-year-old population of Shahroud as a Middle Eastern population. The first phase of the study was conducted in 2009-10. Using random cluster sampling, 6311 Shahroud inhabitants w...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dys161
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Several studies have shown that inactivated, whole-cell oral cholera vaccines (OCVs) confer both direct protection on vaccinees and herd protection on populations. Because our earlier cluster-randomized effectiveness trial (CRT) in urban Bangladesh failed to detect OCV herd protection, we reanalysed the tria...
journal_title:International journal of epidemiology
pub_type: 杂志文章,随机对照试验
doi:10.1093/ije/dyz060
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:France has the second highest number of variant Creutzfeldt-Jakob disease (vCJD) cases worldwide. Imports of bovine carcasses from the UK probably constituted the main source of exposure of the French population to the bovine spongiform encephalopathy (BSE) agent. Meat products consumed whilst visiting the U...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyh374
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:A growing body of literature suggests that physical activity may be a protective factor against hip fracture. METHODS:To study the association between hip fracture risk and recreational physical activity at various ages, changes in activity during adult life, occupational physical activity and how risks var...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/29.2.308
更新日期:2000-04-01 00:00:00
abstract::Chronic diseases are a global problem, yet information on their determinants is generally scant in low- and middle-income countries. The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) aims to contribute relevant information regarding the development and progression of clinical and subclinical chronic disea...
journal_title:International journal of epidemiology
pub_type: 杂志文章
doi:10.1093/ije/dyu027
更新日期:2015-02-01 00:00:00