Abstract:
:The need for reliable results in Toxicological Analysis is recognized and required worldwide. The analytical validation ensures that a method will provide trustworthy information about a particular sample when applied in accordance with a predefined protocol, being able to determine a specific analyte at a distinct concentration range for a well-defined purpose. The driving force for developing method validation for bioanalytical projects comes from the regulatory agencies. Thus, the approach of this work is to present theoretical and practical aspects of method validation based on the analysis objective, whether for prevention or diagnosis. Although various legislative bodies accept differing interpretations of requirements for validation, the process for applying validation criteria should be adaptable for each scientific intent or analytical purpose.
journal_name
Toxicol Mech Methodsjournal_title
Toxicology mechanisms and methodsauthors
Abrão LCC,Silveira AT,de Faria HD,Machado SC,Mendes TV,Plácido RV,Marciano LPA,Martins Idoi
10.1080/15376516.2020.1839612subject
Has Abstractpub_date
2021-01-01 00:00:00pages
18-32issue
1eissn
1537-6516issn
1537-6524journal_volume
31pub_type
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