Cobalt-catalyzed deoxygenative triborylation of allylic ethers to access 1,1,3-triborylalkanes.

abstract：:An egg must be fertilized by a single sperm only. To prevent polyspermy, the zona pellucida, a structure that surrounds mammalian eggs, becomes impermeable upon fertilization, preventing the entry of further sperm. The structural changes in the zona upon fertilization are driven by the exocytosis of cortical granules....

journal_title：Nature communications

authors： Cheeseman LP,Boulanger J,Bond LM,Schuh M

更新日期：2016-12-19 00:00:00

abstract：:Germline removal provokes longevity in several species and shifts resources towards survival and repair. Several Caenorhabditis elegans transcription factors regulate longevity arising from germline removal; yet, how they work together is unknown. Here we identify a Myc-like HLH transcription factor network comprised ...

journal_title：Nature communications

authors： Nakamura S,Karalay Ö,Jäger PS,Horikawa M,Klein C,Nakamura K,Latza C,Templer SE,Dieterich C,Antebi A

更新日期：2016-03-22 00:00:00

abstract：:Natural killer (NK) cells are reported to have immunological memory, with CD49a+ liver-resident NK cells shown to confer hapten-specific memory responses, but how this memory is induced or maintained is unclear. Here we show that memory type I innate lymphoid cells (ILC1s), which express IL-7Rα, are generated in the l...

journal_title：Nature communications

authors： Wang X,Peng H,Cong J,Wang X,Lian Z,Wei H,Sun R,Tian Z

更新日期：2018-11-19 00:00:00

abstract：:Mutations in patatin-like phospholipase domain-containing 1 (PNPLA1) cause autosomal recessive congenital ichthyosis, but the mechanism involved remains unclear. Here we show that PNPLA1, an enzyme expressed in differentiated keratinocytes, plays a crucial role in the biosynthesis of ω-O-acylceramide, a lipid componen...

journal_title：Nature communications

authors： Hirabayashi T,Anjo T,Kaneko A,Senoo Y,Shibata A,Takama H,Yokoyama K,Nishito Y,Ono T,Taya C,Muramatsu K,Fukami K,Muñoz-Garcia A,Brash AR,Ikeda K,Arita M,Akiyama M,Murakami M

更新日期：2017-03-01 00:00:00

abstract：:The continued convergence of electronics and photonics on the chip scale can benefit from the voltage control of optical polarization for applications in communications, signal processing and sensing. It is challenging, however, to electrically manipulate the polarization state of light in planar optical waveguides. H...

journal_title：Nature communications

authors： Xu Q,Chen L,Wood MG,Sun P,Reano RM

更新日期：2014-11-12 00:00:00

abstract：:Solar-driven photocatalysis has attracted significant attention in water splitting, CO2 reduction and organic synthesis. The syntheses of valuable azo- and azoxyaromatic dyes via selective photoreduction of nitroaromatic compounds have been realised using supported plasmonic metal nanoparticles at elevated temperature...

journal_title：Nature communications

authors： Dai Y,Li C,Shen Y,Lim T,Xu J,Li Y,Niemantsverdriet H,Besenbacher F,Lock N,Su R

更新日期：2018-01-04 00:00:00

abstract：:Substance abuse disorders are linked to alteration of circadian rhythms, although the molecular and neuronal pathways implicated have not been fully elucidated. Addictive drugs, such as cocaine, induce a rapid increase of dopamine levels in the brain. Here, we show that acute administration of cocaine triggers reprogr...

journal_title：Nature communications

authors： Brami-Cherrier K,Lewis RG,Cervantes M,Liu Y,Tognini P,Baldi P,Sassone-Corsi P,Borrelli E

更新日期：2020-09-07 00:00:00

abstract：:The coupling of compartmentalisation with molecular replication is thought to be crucial for the emergence of the first evolvable chemical systems. Minimal artificial replicators have been designed based on molecular recognition, inspired by the template copying of DNA, but none yet have been coupled to compartmentali...

journal_title：Nature communications

authors： Taylor JW,Eghtesadi SA,Points LJ,Liu T,Cronin L

更新日期：2017-08-10 00:00:00

abstract：:Current mitigation efforts and existing future commitments are inadequate to accomplish the Paris Agreement temperature goals. In light of this, research and debate are intensifying on the possibilities of additionally employing proposed climate geoengineering technologies, either through atmospheric carbon dioxide re...

journal_title：Nature communications

authors： Lawrence MG,Schäfer S,Muri H,Scott V,Oschlies A,Vaughan NE,Boucher O,Schmidt H,Haywood J,Scheffran J

更新日期：2018-09-13 00:00:00

abstract：:The discovery of superconductivity at 260 K in hydrogen-rich compounds like LaH10 re-invigorated the quest for room temperature superconductivity. Here, we report the temperature dependence of the upper critical fields μ0Hc2(T) of superconducting H3S under a record-high combination of applied pressures up to 160 GPa a...

journal_title：Nature communications

authors： Mozaffari S,Sun D,Minkov VS,Drozdov AP,Knyazev D,Betts JB,Einaga M,Shimizu K,Eremets MI,Balicas L,Balakirev FF

更新日期：2019-06-07 00:00:00

abstract：:In November 2013, a series of earthquakes began along a mapped ancient fault system near Azle, Texas. Here we assess whether it is plausible that human activity caused these earthquakes. Analysis of both lake and groundwater variations near Azle shows that no significant stress changes were associated with the shallow...

journal_title：Nature communications

authors： Hornbach MJ,DeShon HR,Ellsworth WL,Stump BW,Hayward C,Frohlich C,Oldham HR,Olson JE,Magnani MB,Brokaw C,Luetgert JH

更新日期：2015-04-21 00:00:00

abstract：:Tuning the thermodynamic state of a material has a tremendous impact on its performance. In the case of polymers placed in proximity of a solid wall, this is possible by annealing above the glass transition temperature, Tg, which induces the formation of an adsorbed layer. Whether heating to higher temperatures would ...

journal_title：Nature communications

authors： Monnier X,Napolitano S,Cangialosi D

更新日期：2020-08-28 00:00:00

abstract：:The mid-Pliocene Warm Period (mPWP) offers an opportunity to understand a warmer-than-present world and assess the predictive ability of numerical climate models. Environmental reconstruction and climate modelling are crucial for understanding the mPWP, and the synergy of these two, often disparate, fields has proven ...

journal_title：Nature communications

authors： Haywood AM,Dowsett HJ,Dolan AM

更新日期：2016-02-16 00:00:00

abstract：:The rapidly increasing use of sensors throughout different research disciplines and the demand for more efficient devices with less power consumption depends critically on the emergence of new sensor materials and novel sensor concepts. Atomically thin transition metal dichalcogenides have a huge potential for sensor ...

journal_title：Nature communications

authors： Feierabend M,Berghäuser G,Knorr A,Malic E

更新日期：2017-03-15 00:00:00

abstract：:Covalent functionalization tailors carbon nanotubes for a wide range of applications in varying environments. Its strength and stability of attachment come at the price of degrading the carbon nanotubes sp2 network and destroying the tubes electronic and optoelectronic features. Here we present a non-destructive, cova...

journal_title：Nature communications

authors： Setaro A,Adeli M,Glaeske M,Przyrembel D,Bisswanger T,Gordeev G,Maschietto F,Faghani A,Paulus B,Weinelt M,Arenal R,Haag R,Reich S

更新日期：2017-01-30 00:00:00

abstract：:Genetic heterogeneity between and within tumours is a major factor determining cancer progression and therapy response. Here we examined DNA sequence and DNA copy-number heterogeneity in colorectal cancer (CRC) by targeted high-depth sequencing of 100 most frequently altered genes. In 97 samples, with primary tumours ...

journal_title：Nature communications

authors： Mamlouk S,Childs LH,Aust D,Heim D,Melching F,Oliveira C,Wolf T,Durek P,Schumacher D,Bläker H,von Winterfeld M,Gastl B,Möhr K,Menne A,Zeugner S,Redmer T,Lenze D,Tierling S,Möbs M,Weichert W,Folprecht G,Blanc E,

更新日期：2017-01-25 00:00:00

abstract：:Pollinators tend to be preferentially attracted to large floral displays that may comprise more than one plant in a patch. Attracting pollinators thus not only benefits individuals investing in advertising, but also other plants in a patch through a 'magnet' effect. Accordingly, there could be an indirect fitness adva...

journal_title：Nature communications

authors： Torices R,Gómez JM,Pannell JR

更新日期：2018-05-22 00:00:00

abstract：:Zika virus (ZIKV) is an emerging mosquito borne flavivirus and a major public health concern causing severe disease. Due to the presence of a lipid membrane and structural heterogeneity, attaining an atomic resolution structure is challenging, but important to understand virus assembly and life cycle mechanisms that o...

journal_title：Nature communications

authors： DiNunno NM,Goetschius DJ,Narayanan A,Majowicz SA,Moustafa I,Bator CM,Hafenstein SL,Jose J

更新日期：2020-10-02 00:00:00

abstract：:ASXL2 is frequently mutated in acute myeloid leukaemia patients with t(8;21). However, the roles of ASXL2 in normal haematopoiesis and the pathogenesis of myeloid malignancies remain unknown. Here we show that deletion of Asxl2 in mice leads to the development of myelodysplastic syndrome (MDS)-like disease. Asxl2-/- m...

journal_title：Nature communications

authors： Li J,He F,Zhang P,Chen S,Shi H,Sun Y,Guo Y,Yang H,Man N,Greenblatt S,Li Z,Guo Z,Zhou Y,Wang L,Morey L,Williams S,Chen X,Wang QT,Nimer SD,Yu P,Wang QF,Xu M,Yang FC

更新日期：2017-06-08 00:00:00

abstract：:Efficient organic light-emitting diodes have been developed using emitters containing rare metals, such as platinum and iridium complexes. However, there is an urgent need to develop emitters composed of more abundant materials. Here we show a thermally activated delayed fluorescence material for organic light-emittin...

journal_title：Nature communications

authors： Kaji H,Suzuki H,Fukushima T,Shizu K,Suzuki K,Kubo S,Komino T,Oiwa H,Suzuki F,Wakamiya A,Murata Y,Adachi C

更新日期：2015-10-19 00:00:00

abstract：:Polar van der Waals chalcogenophosphates exhibit unique properties, such as negative electrostriction and multi-well ferrielectricity, and enable combining dielectric and 2D electronic materials. Using low temperature piezoresponse force microscopy, we revealed coexistence of piezoelectric and non-piezoelectric phases...

journal_title：Nature communications

authors： Dziaugys A,Kelley K,Brehm JA,Tao L,Puretzky A,Feng T,O'Hara A,Neumayer S,Chyasnavichyus M,Eliseev EA,Banys J,Vysochanskii Y,Ye F,Chakoumakos BC,Susner MA,McGuire MA,Kalinin SV,Ganesh P,Balke N,Pantelides ST,Morozo

更新日期：2020-07-17 00:00:00

abstract：:The separation of immiscible liquids has significant implications for magma evolution and the formation of magmatic ore deposits. We combine high-resolution imaging and electron probe microanalysis with the first use of atom probe tomography on tholeiitic basaltic glass from Hawaii, the Snake River Plain, and Iceland,...

journal_title：Nature communications

authors： Honour VC,Holness MB,Charlier B,Piazolo SC,Namur O,Prosa TJ,Martin I,Helz RT,Maclennan J,Jean MM

更新日期：2019-10-23 00:00:00

abstract：:Broomcorn millet (Panicum miliaceum L.) has strong tolerance to abiotic stresses, and is probably one of the oldest crops, with its earliest cultivation that dated back to ca. ~10,000 years. We report here its genome assembly through a combination of PacBio sequencing, BioNano, and Hi-C (in vivo) mapping. The 18 super...

journal_title：Nature communications

authors： Shi J,Ma X,Zhang J,Zhou Y,Liu M,Huang L,Sun S,Zhang X,Gao X,Zhan W,Li P,Wang L,Lu P,Zhao H,Song W,Lai J

更新日期：2019-01-25 00:00:00

abstract：:Plasmodium vivax poses unique challenges for malaria control and elimination, notably the potential for relapses to maintain transmission in the face of drug-based treatment and vector control strategies. We developed an individual-based mathematical model of P. vivax transmission calibrated to epidemiological data fr...

journal_title：Nature communications

authors： White MT,Walker P,Karl S,Hetzel MW,Freeman T,Waltmann A,Laman M,Robinson LJ,Ghani A,Mueller I

更新日期：2018-08-17 00:00:00

abstract：:Many cancer cells display enhanced glycolysis and suppressed mitochondrial metabolism. This phenomenon, known as the Warburg effect, is critical for tumor development. However, how cancer cells coordinate glucose metabolism through glycolysis and the mitochondrial tricarboxylic acid (TCA) cycle is largely unknown. We ...

journal_title：Nature communications

authors： Nie H,Ju H,Fan J,Shi X,Cheng Y,Cang X,Zheng Z,Duan X,Yi W

更新日期：2020-01-07 00:00:00

abstract：:Nanofabricated and nanopatterned surfaces have revealed the sensitivity of cell adhesion to nanoscale variations in the spacing of adhesive ligands such as the tripeptide arginine-glycine-aspartic acid (RGD). To date, surface characterisation and cell adhesion are often examined in two separate experiments so that the...

journal_title：Nature communications

authors： Lu X,Nicovich PR,Zhao M,Nieves DJ,Mollazade M,Vivekchand SRC,Gaus K,Gooding JJ

更新日期：2018-08-20 00:00:00

abstract：:Influenza viruses annually kill 290,000-650,000 people worldwide. Antivirals can reduce death tolls. Baloxavir, the recently approved influenza antiviral, inhibits initiation of viral mRNA synthesis, whereas oseltamivir, an older drug, inhibits release of virus progeny. Baloxavir blocks virus replication more rapidly ...

journal_title：Nature communications

authors： Du Z,Nugent C,Galvani AP,Krug RM,Meyers LA

更新日期：2020-06-02 00:00:00

abstract：:Glucagon is released from pancreatic α-cells to activate pathways that raise blood glucose. Its secretion is regulated by α-cell-intrinsic glucose sensing and paracrine control through insulin and somatostatin. To understand the inadequately high glucagon levels that contribute to hyperglycemia in type-2 diabetes (T2D...

journal_title：Nature communications

authors： Omar-Hmeadi M,Lund PE,Gandasi NR,Tengholm A,Barg S

更新日期：2020-04-20 00:00:00

abstract：:Inspired by mammalian skins, soft hybrids integrating the merits of elastomers and hydrogels have potential applications in diverse areas including stretchable and bio-integrated electronics, microfluidics, tissue engineering, soft robotics and biomedical devices. However, existing hydrogel-elastomer hybrids have limi...

journal_title：Nature communications

authors： Yuk H,Zhang T,Parada GA,Liu X,Zhao X

更新日期：2016-06-27 00:00:00

abstract：:The interaction of lipids and proteins plays an important role in plasma membrane bioactivity, and much can be learned from their diffusion characteristics. Here we present the combination of super-resolution STED microscopy with scanning fluorescence correlation spectroscopy (scanning STED-FCS, sSTED-FCS) to characte...

journal_title：Nature communications

authors： Honigmann A,Mueller V,Ta H,Schoenle A,Sezgin E,Hell SW,Eggeling C

更新日期：2014-11-20 00:00:00